JP2022117831A - Fundus imaging apparatus - Google Patents

Abstract

To provide a fundus imaging apparatus which can acquire an excellent image correspondingly to each operation of fundus observation, fluorescent observation and fluorescent photography with infrared light.SOLUTION: A fundus imaging apparatus 200 that projects illumination light to a fundus EB of a subject eye EY via scanning devices 30, 50 and an objective lens system 60, and receives emission light from the fundus EB via the objective lens system 60 comprises: an infrared light source 10b which emits infrared light as the illumination light; a light receiving element 70b for infrared light which receives infrared fluorescent light excited by infrared reflection light or infrared light as emission light; a first optical filter F1 which is provided in a light reception path of the infrared light in an insertable/detachable manner and selectively transmits the infrared fluorescent light; and a photography preparation light shielding member 92 which is provided in the light reception path of the infrared light and is configured to be movable between the light shielding position of locally shielding harmful light and the non-light shielding position having the lower light shielding degree than that of the light shielding position.SELECTED DRAWING: Figure 2

Description

The present invention relates to a fundus photographing apparatus for photographing a fundus image of an eye to be examined, and more particularly to a fundus photographing apparatus capable of obtaining a good image depending on whether observation light is non-fluorescent or fluorescent.

In a scanning laser ophthalmoscope (SLO), harmful light is blocked by a light blocking member (specifically, a dot-shaped light blocking body, hereinafter also referred to as a black dot) placed in the common light receiving optical path for visible light and infrared light. Then, observation of the fundus and photographing of color images are performed. In SLO, when performing fluorescence imaging, alignment is performed using a fundus observation image using infrared light, and then imaging is performed by inserting an optical filter that selectively transmits fluorescence into the light receiving optical path (for example, See Patent Document 1).

However, the light blocking member not only blocks harmful light, but also partially blocks light such as fluorescent light that should be used for photographing. For this reason, in the above SLO, light is blocked by the optical filter and the light shielding member in a double manner during fluorescence imaging, resulting in a problem that the amount of light is insufficient and the image becomes dark.

JP 2020-157098 A

SUMMARY OF THE INVENTION The present invention has been made in view of the problems of the above-described background art, and provides a fundus photographing capable of obtaining good images corresponding to each operation of fundus observation using infrared light, fluorescence observation, and fluorescence photographing. The purpose is to provide an apparatus.

In order to achieve the above object, a fundus imaging apparatus according to the present invention projects illumination light onto the fundus of a subject's eye via a scanning optical system and an objective lens, and receives light emitted from the fundus via the objective lens. A fundus imaging device, comprising: an infrared light source emitting infrared light as illumination light; and an infrared light receiving element receiving reflected infrared light as emitted light or infrared fluorescence excited by the infrared light; a first optical filter that is detachably provided in an infrared light receiving optical path and that selectively transmits infrared fluorescence; and a light shielding position that is provided in the infrared light receiving optical path and locally shields harmful light. and a photographing preparation light-shielding member configured to be movable between a non-light-shielding position having a lower degree of light-shielding than a light-shielding position. Here, the photographing preparation light shielding member may be arranged on the light receiving optical path or outside the light receiving optical path at the non-light blocking position.

The fundus imaging apparatus includes the imaging preparation light shielding member and the first optical filter, the imaging preparation light shielding member is configured to be movable between the light shielding position and the non-light shielding position, and the first optical filter is inserted into and removed from the light receiving optical path. possible configuration, and by appropriately changing the arrangement of the imaging preparation light shielding member and the first optical filter corresponding to each operation of infrared observation, infrared fluorescence observation, and infrared fluorescence imaging, reflected infrared light or infrared light The amount of fluorescent light can be adjusted appropriately. Accordingly, it is possible to obtain a good image corresponding to each motion.

According to a specific aspect of the present invention, in the fundus imaging apparatus described above, when the infrared fluorescence imaging mode is selected, the first optical filter is retracted from the infrared light receiving optical path during image detection before imaging. controls the imaging preparation light shielding member to be placed at the light shielding position, and when an infrared fluorescence imaging trigger is recognized, the first optical filter is inserted into the infrared light receiving optical path, and the imaging preparation light shielding member is shielded. It further comprises a control unit that controls movement from the position to the non-light blocking position. In this case, during image detection before photographing in the infrared fluorescence photographing mode, a clear infrared image can be obtained by removing harmful light by the photographing preparation light shielding member provided at the light shielding position. Further, during infrared fluorescence imaging, the imaging preparation light shielding member is moved to the non-light shielding position, harmful light is removed using only the first optical filter, and a sufficient amount of light necessary for good image imaging is ensured. It is possible to obtain clear and bright fluorescence images.

According to another aspect of the present invention, a visible light source that emits visible light as illumination light, a visible light receiving element that receives visible reflected light as emitted light or visible fluorescence excited by visible light, and infrared light and visible light, and is movable along the common light receiving optical path between a light blocking position that locally blocks harmful light and a non-light blocking position that blocks less light than the light blocking position. and a configured visible light blocking member. Here, the visible light shielding member is arranged on the light receiving optical path at the non-shielding position. In this case, for example, in a color photographing mode using visible light, a clear color image can be obtained by removing harmful light by providing the visible light blocking member at the blocking position.

According to still another aspect of the present invention, when the infrared fluorescence imaging mode is selected, the visible light shielding member is moved while the first optical filter is retracted from the infrared light receiving optical path during image detection before imaging. A control unit is further provided for performing control for moving the photographing preparation light shielding member from the light shielding position to the non-light shielding position and placing the photographing preparation light shielding member at the light shielding position. In this case, even if the visible light shielding member is retracted to the non-shielding position during image detection before photographing in the infrared fluorescence photographing mode, harmful light is removed by the photographing preparation light shielding member in the light shielding position to obtain a clean infrared image. Images can be acquired.

According to still another aspect of the present invention, it further comprises a second optical filter that is detachably provided in the light receiving optical path of visible light and that selectively transmits visible fluorescence, and the imaging preparation light shielding member is configured to block infrared light. Provided in a dedicated light receiving optical path, when a visible fluorescence photographing mode is selected, the visible light shielding member is moved from the light shielding position to the non-shielding position during image detection before photographing, and the photographing preparation light shielding member is arranged at the light shielding position. The apparatus further includes a control unit that performs control and performs control to insert the second optical filter into the light receiving optical path of visible light before or after the imaging trigger of visible fluorescence is recognized. In this case, during image detection before photography in the visible fluorescence photography mode, the visible light blocking member is retracted to the non-light blocking position, and then harmful light is removed by the photography preparation light blocking member at the light blocking position to obtain a clear infrared light. A fundus image can be acquired. Further, during visible fluorescence imaging, the imaging preparation light shielding member disposed outside the optical path for receiving visible light does not affect the optical path for receiving visible light, and only the second optical filter is used to remove harmful light. A clear and bright fluorescence image can be obtained by securing a sufficient amount of light necessary for taking a good image. Here, visible fluorescence is not limited to visible fluorescence emitted by fluorescein, which is a contrast agent, but also includes visible autofluorescence mainly emitted by lipofuscin in the retinal pigment epithelium.

According to still another aspect of the present invention, the photographing preparation light shielding member includes a first photographing preparation light shielding member that is detachably provided in a light receiving optical path dedicated to infrared light. In this case, the first photographing preparation light shielding member moves in the direction perpendicular to the optical path between the light shielding position and the non-light shielding position while the position on the light receiving optical path is fixed.

According to still another aspect of the present invention, the imaging preparation light shielding member includes a second imaging preparation light shielding member provided movably along a light receiving optical path dedicated to infrared light. In this case, the second photographing preparation light shielding member is variable in its position on the light receiving optical path, and moves in the direction along the optical path between the light shielding position and the non-light shielding position.

According to still another aspect of the present invention, it further comprises a second optical filter that is detachably provided in the light receiving optical path of visible light and that selectively transmits visible fluorescence, and the photographing preparation light shielding member is placed in the common light receiving optical path. When the visible fluorescence imaging mode is selected, the visible light shielding member is moved from the shielding position to the non-shielding position during image detection before photographing, and the imaging preparation shielding member is placed in the shielding position. When the fluorescence imaging trigger is recognized, control is performed to move the imaging preparation light shielding member from the light shielding position to the non-light shielding position, and before or after the visible fluorescence imaging trigger is recognized, the second optical filter is turned on for the visible light. It further comprises a control unit that controls insertion into the light receiving optical path. In this case, during image detection before photography in the visible fluorescence photography mode, the visible light blocking member is retracted to the non-light blocking position, and then harmful light is removed by the photography preparation light blocking member at the light blocking position to obtain a clear infrared light. A fundus image can be acquired. Further, during visible fluorescence imaging, by moving the imaging preparation light-shielding member to the non-light-shielding position and using only the second optical filter to remove harmful light, a sufficient amount of light necessary for good image imaging can be ensured. , a clear and bright fluorescence image can be obtained.

According to still another aspect of the present invention, the photographing preparation light shielding member includes a third photographing preparation light shielding member which is detachably provided in the common light receiving optical path. In this case, the third photographing preparation light blocking member moves in the direction perpendicular to the optical path between the light blocking position and the non-light blocking position while the position on the light receiving optical path is fixed.

According to still another aspect of the present invention, the moving time of the photographing preparation light blocking member from the light blocking position to the non-light blocking position is shorter than the moving time of the visible light blocking member from the light blocking position to the non-light blocking position. In this case, it is possible to shorten the light amount adjustment time between infrared observation and fluorescence observation or fluorescence imaging by the imaging preparation light-shielding member that quickly switches between the light-shielding position and the non-light-shielding position.

According to still another aspect of the present invention, the light shielding position of the visible light shielding member is changed according to the diopter of the subject's eye. In this case, for example, in a color photographing mode using visible light, the visible light shielding member can be arranged at a light shielding position, which is a position suitable for shielding according to the diopter of the subject's eye, in accordance with diopter correction.

In order to achieve the above object, a fundus imaging apparatus according to the present invention projects illumination light onto the fundus of a subject's eye via a scanning optical system and an objective lens, and receives light emitted from the fundus via the objective lens. A fundus imaging device comprising a visible light source that emits visible light as illumination light, a visible light receiving element that receives visible reflected light as emitted light or visible fluorescence excited by visible light, and a visible light receiving optical path. A second optical filter that is detachably provided to selectively transmit visible fluorescence, a light shielding position that is provided in the light receiving optical path of visible light and locally shields harmful light, and a light shielding degree lower than that of the light shielding position. a photographing preparation light shielding member that is configured to be insertable and removable in the light receiving optical path between the light shielding position and the non-light shielding position.

The fundus imaging apparatus includes the imaging preparation light shielding member and the second optical filter, the imaging preparation light shielding member is configured to be insertable and removable in the light receiving optical path between the light shielding position and the non-light shielding position, and the second optical filter receives the light. The amount of visible reflected light or visible fluorescent light can be reduced by appropriately changing the arrangement of the imaging preparation light-shielding member and the second optical filter corresponding to each operation of visible observation, visible fluorescence observation, and imaging. can be adjusted appropriately. Accordingly, it is possible to obtain a good image corresponding to each motion.

1 is a side view for explaining the fundus imaging device of the first embodiment; FIG. FIG. 2 is a conceptual diagram mainly explaining the optical structure of the fundus imaging apparatus shown in FIG. 1; FIG. 3 is a conceptual diagram mainly explaining an imaging preparation light shielding member and a visible light shielding member in the optical structure of the fundus imaging apparatus shown in FIG. 2 ; (A) is a conceptual diagram illustrating the arrangement of an imaging preparation light shielding member and a visible light shielding member during image detection before imaging of the fundus imaging apparatus shown in FIG. 2, and (B) is an infrared fluorescence imaging mode selection; FIG. 11 is a conceptual diagram illustrating the arrangement of a post-imaging preparation light shielding member and a visible light shielding member. 3A is a conceptual diagram illustrating the arrangement of an imaging preparation light shielding member, a visible light shielding member, and a first optical filter during infrared fluorescence imaging in an infrared fluorescence imaging mode of the fundus imaging apparatus shown in FIG. 2; (B) is a conceptual diagram illustrating the arrangement of an imaging preparation light shielding member, a visible light shielding member, and a second optical filter during visible fluorescence imaging in a visible fluorescence imaging mode. 4 is a flowchart for explaining the operation of the fundus imaging device; FIG. 10 is a conceptual diagram for explaining a fundus imaging device of a second embodiment; FIG. 8A is a conceptual diagram illustrating the arrangement of an imaging preparation light shielding member and a visible light shielding member during image detection before imaging of the fundus imaging apparatus shown in FIG. 7, and FIG. 8B is an infrared fluorescence imaging mode selection; FIG. 11 is a conceptual diagram illustrating the arrangement of a post-imaging preparation light shielding member and a visible light shielding member. 8A is a conceptual diagram illustrating the arrangement of an imaging preparation light shielding member, a visible light shielding member, and a first optical filter during infrared fluorescence imaging in an infrared fluorescence imaging mode of the fundus imaging apparatus shown in FIG. 7; (B) is a conceptual diagram illustrating the arrangement of an imaging preparation light shielding member, a visible light shielding member, and a second optical filter during visible fluorescence imaging in a visible fluorescence imaging mode. FIG. 8 is a conceptual diagram illustrating a modification of the fundus imaging device shown in FIG. 7;

[First embodiment]
A fundus imaging apparatus 200 according to a first embodiment of the present invention will be described below with reference to FIG. 1 and the like.

The fundus imaging device 200 includes an optical unit section 201 , a chinrest section 203 and a pedestal section 205 . The optical unit section 201 has a fundus photographing system 100 for observing the fundus of the subject's eye EY, as well as various mechanisms such as a control circuit and a driving device (not shown) incorporated in a housing 201a. The optical unit section 201 is supported by a stage 301 , and the stage 301 is three-dimensionally movable together with the optical unit section 201 by a driving mechanism 302 .

In the optical unit section 201, a monitor 201c is provided on the upper side of the operator's side so that the operator can view the fundus and other observation images, control information related to the imaging operation, and the like with the naked eye.

The chinrest section 203 is attached to face the side surface of the optical unit section 201 on the subject side. Although the detailed description is omitted, the chin rest section 203 has a plurality of contact sections for fixing the chin and forehead of the subject. The height of the subject's eye can be adjusted and fixed relative to the optical unit section 201 so as to face the objective lens section 201 e of the fundus imaging system 100 .

The mount section 205 supports the optical unit section 201 and the jaw rest section 203 . An operation unit 205i including operation keys and levers is provided on the upper surface of the operator side portion of the pedestal unit 205, and the operator can control the operating state of the fundus imaging apparatus 200 while observing the monitor 201c. It is possible.

FIG. 2 is a diagram for explaining the internal structure of the fundus imaging device 200 shown in FIG. The fundus imaging device 200 includes a fundus imaging system 100 as a main optical system and a control device 80 as an operation control system. The fundus imaging system 100 is a main part that enables observation and imaging of the fundus EB of the subject's eye EY using scanning light. The control device 80 performs various controls regarding the imaging operation and measurement operation of the fundus imaging device 200 for each unit that configures the fundus imaging device 200 . The fundus imaging device 200 can capture a fundus image using the fundus imaging system 100 or the like, and display the fundus image on the monitor 201c shown in FIG. Note that the fundus imaging apparatus 200 may be integrated with other ophthalmologic apparatus such as an optical coherence tomograph and a perimeter.

The fundus imaging system 100 is a scanning fundus imaging unit, and has a light projecting optical system 100a and a light receiving optical system 100b. The fundus imaging system 100 scans the fundus EB with a laser beam that is projected light ML (illumination light), and photographs a fundus image based on the reflected light RL (emission light) from the fundus EB. The fundus imaging system 100 of the present embodiment performs wide-angle imaging with an angle of view of 60° or more, for example. Here, for example, the angle of view of 60° means the maximum angle of view at which the fundus EB can be photographed, and corresponds to the maximum scanning angle of the projected light ML rotating on the pupil plane PS of the eye EY to be examined. The fundus imaging system 100 has a fundus observation mode for capturing a moving image of an object when obtaining a fundus image, a color imaging mode for capturing a single color image, and a visible autofluorescence imaging mode for capturing a single visible autofluorescence image. , a visible fluorescence imaging mode that captures one visible fluorescence image or a moving image, and a near-infrared fluorescence imaging mode that captures one near-infrared fluorescence image or a moving image. It's becoming Here, the fundus observation mode is used for alignment for position adjustment of the eye EY or fundus EB to be examined and focus adjustment for image formation.

A projection optical system 100 a of the fundus imaging system 100 includes a light source unit 10 , a central reflecting mirror 20 , a first scanning device 30 , a scanning relay lens system 40 , a second scanning device 50 , and an objective lens system 60 . have The light receiving optical system 100 b includes an objective lens system 60 , a second scanning device 50 , a scanning relay lens system 40 , a first scanning device 30 , a central reflection mirror 20 and a light receiving section 70 . The objective lens system 60, the first scanning device 30, the scanning relay lens system 40, the second scanning device 50, and the central reflecting mirror 20 function both as part of the projecting optical system 100a and as part of the receiving optical system 100b. do.

The light source unit 10 of the light projecting optical system 100a includes a red laser 11 that emits red light, a green laser 12 that emits green light, a blue laser 13 that emits blue light, and a near-infrared laser 14 that emits near-infrared light. , a first dichroic mirror 15, a second dichroic mirror 16, a third dichroic mirror 17, a projection lens 18, a projection focus lens 19, and a projection pinhole P1. The red laser 11, the green laser 12, and the blue laser 13 in the light source unit 10 constitute a visible light source 10a that emits visible light. Also, the near-infrared laser 14 constitutes an infrared light source 10b that emits near-infrared light. The infrared light source 10b may emit infrared light other than near-infrared light.

The red light emitted from the red laser 11 passes through the first dichroic mirror 15, the second dichroic mirror 16, and the third dichroic mirror 17, passes through the projection lens 18 and the projection focus lens 19, and reaches the central reflection mirror 20. Incident. The green light emitted from the green laser 12 is reflected by the first dichroic mirror 15, passes through the second dichroic mirror 16 and the third dichroic mirror 17, passes through the projection lens 18 and the projection focus lens 19, and reaches the center. Incident on the reflecting mirror 20 . The blue light emitted from the blue laser 13 is reflected by the second dichroic mirror 16, passes through the third dichroic mirror 17, passes through the projection lens 18 and the projection focus lens 19, and enters the central reflection mirror 20. . The near-infrared light emitted from the near-infrared laser 14 is reflected by the third dichroic mirror 17 , passes through the projection lens 18 and the projection focus lens 19 , and enters the central reflection mirror 20 .

Near-infrared light is used in a fundus observation mode, a near-infrared fluorescence imaging mode for still photography, and a near-infrared fluorescence imaging mode for continuous photography, which will be described later. Red light included in visible light is used in a color photography mode. Green light included in visible light is used in color imaging mode and visible autofluorescence imaging mode, and blue light included in visible light is used in color imaging mode, visible autofluorescence imaging mode, visible fluorescence imaging mode for still imaging, and in the visible fluorescence imaging mode for continuous imaging.

In this embodiment, the peak wavelength of the red light emitted from the red laser 11 is, for example, 650 nm, and is preferably set within the range of 650 nm±10 nm. The peak wavelength of green light emitted from the green laser 12 is, for example, 561 nm, and is preferably set within the range of 560 nm±10 nm. The peak wavelength of green light is, for example, 532 nm as a second candidate, but is preferably set within the range of 530 nm±10 nm. The peak wavelength of blue light emitted from the blue laser 13 is, for example, 488 nm, and is preferably set within the range of 490 nm±10 nm. The peak wavelength of the near-infrared light emitted from the near-infrared laser 14 is, for example, 785 nm, and is preferably set within the range of 785 nm±10 nm. The peak wavelength of the near-infrared light is, for example, 760 nm as a second candidate, but is preferably set within the range of 760 nm±10 nm.

The light projection focus lens 19 is movable along the direction of the optical axis AX1 of the light source unit 10, and focuses the laser light as the projection light ML emitted from each of the lasers 11 to 14 onto the fundus EB of the eye EY to be examined. adjust for. That is, by adjusting the position of the light projection focus lens 19, the projected light beam is focused on the fundus oculi EB in accordance with the diopter of the eye EY to be examined. Thereby, the position where the projected light ML is condensed can be adjusted to the observation site (for example, the surface of the retina, etc.) of the fundus oculi EB. The light projection focus lens 19 is interlocked with the operation of the light reception focus lens 78 of the light reception optical system 100b, which will be described later. The light projection pinhole P1 is provided between the light projection lens 18 and the light projection focus lens 19 and at a position conjugate with the fundus EB, and serves as a confocal diaphragm to remove unnecessary light from the light projection ML. . After passing through the projection lens 18, the projection light ML is focused on the opening of the projection pinhole P1 and enters the projection focus lens 19. When the beam is ejected from the collimated state, it undergoes a slight change so that it becomes a divergent state or a converged state close to the collimated state.

The central reflecting mirror 20 has a reflecting portion in the central portion through which the optical axis AX1 passes. Bend. The projected light ML redirected by the central reflecting mirror 20 is incident on the first scanning device 30 . Note that the peripheral portion of the central reflecting mirror 20 is a transmitting portion, and in the light receiving optical system 100b, the reflected light RL reflected by the fundus EB of the eye EY to be examined travels backward through the objective lens system 60 and the like, and reaches the central reflecting mirror 20. , and enters the light-receiving unit 70, which will be described in detail later.

In order to scan the fundus EB with the projected light ML, the first scanning device 30 changes the advancing direction of the projected light ML with respect to the horizontal lateral direction corresponding to main scanning. The first scanning device 30 is composed of, for example, a polygon mirror. The first scanning device 30 is rotationally driven at a predetermined number of rotations by the driving section 82 of the control device 80, and main-scans the projected light ML in the lateral direction or the horizontal direction (X direction) at high speed with the periphery of the optical axis AX2 as the base point. The projected light ML scanned by the first scanning device 30 enters the scanning relay lens system 40 . The polygon mirror, which is the first scanning device 30, performs continuous scanning, for example, 7500 times per second.

The scanning relay lens system 40 relays the projected light ML scanned in the horizontal lateral direction by the first scanning device 30 to the second scanning device 50 . The projected light ML that has passed through the scanning relay lens system 40 is focused on the second scanning device 50 . A fundus conjugate plane EC is arranged in the middle of the scanning relay lens system 40 .

In order to scan the fundus EB with the projected light ML, the second scanning device 50 changes the advancing direction of the projected light ML with respect to the vertical direction corresponding to sub-scanning. The second scanning device 50 is composed of, for example, a galvanomirror. The second scanning device 50 is reciprocatingly driven at a predetermined cycle by the driving unit 82 of the control device 80, and the projected light ML is directed vertically or in a direction orthogonal to the main scanning direction of the first scanning device 30 ( (Y direction) at a low speed. The projected light ML scanned by the second scanning device 50 enters the objective lens system 60 as scanning light. Between the second scanning device 50 and the pupil plane PS of the eye EY to be inspected, the principal rays of the projected light beams at different scanning angles do not intersect on the optical axis AX2. In other words, between the second scanning device 50 and the pupil plane PS of the eye EY to be inspected, the chief rays of the scanning light beams or projected light beams having different scanning angles are separated from each other. As a result, imaging accuracy can be improved with a simple lens configuration. The galvanomirror, which is the second scanning device 50, continuously scans 13 times per second in the fundus observation mode using near-infrared light, for example. Color photography mode using red, green, and blue light, visible autofluorescence photography mode using green or blue light, or visible fluorescence photography mode using blue light, or near-infrared photography using near-infrared light During single image photography in the external fluorescence photography mode, one scan is performed in 0.4 seconds. Further, during moving image capturing in the visible fluorescence capturing mode using blue light or moving image capturing in the near-infrared fluorescence capturing mode using near-infrared light, scanning is continuously performed 10 times per second.

By scanning the projection light ML using two scanning devices, the first scanning device 30 and the second scanning device 50, the projection light ML two-dimensionally scans the fundus EB of the subject's eye EY in the XY directions. It will be. At this time, if the alignment is appropriately performed, the placement of the fundus imaging system 100 with respect to the eye to be examined EY is appropriate, and the projected light ML passes through the pupil of the pupil plane PS of the eye to be examined EY regardless of the scanning angle. is scanned to In FIG. 2, the two scanning devices, the first scanning device 30 and the second scanning device 50, appear to generate scanning light by transmission, but this is for illustrative purposes only and is actually a reflection, i.e. a reflection mirror. Scanning light is generated by rotation and tilt.

The objective lens system 60 relays the projected light ML scanned in the horizontal and vertical directions (XY directions) by the first and second scanning devices 30 and 50 to the pupil plane PS of the eye EY to be examined. In the example shown in the embodiment, the objective lens system 60 has a front group Gr1 and a rear group Gr2 in order from the pupil plane PS side of the subject's eye EY with the fundus conjugate plane EC as a boundary. By constructing the objective lens system 60 with two groups, the front group Gr1 and the rear group Gr2, the power distribution of the lens can be dispersed between the front group Gr1 and the rear group Gr2. , the amount of movement of the projected light flux on the pupil plane PS due to different scanning angles can be suppressed. Further, by dividing the objective lens system 60 into two groups, a front group Gr1 and a rear group Gr2, with the fundus conjugate plane EC interposed therebetween, the distance from the fundus conjugate plane EC to the adjacent lens is increased, and the reflection of the objective lens surface It is possible to prevent the harmful light generated by the reflection from being reflected in the photographed image of the fundus EB.

In the fundus imaging system 100 , the diopter differs depending on the subject, so the fundus conjugate plane EC moves within the objective lens system 60 when focusing by diopter correction. Here, as described above, the objective lens system 60 has a two-group lens configuration, and even if the fundus conjugate plane EC moves, the lens groups Gr1 and Gr2 do not come close to the lens surfaces located on the fundus conjugate plane EC side. As a result, it is possible to prevent unnecessary reflected light RL and the like from the lens surface of the objective lens system 60 from passing through a light receiving pinhole P2, which will be described later. From this background, the distance between the inner lens surface of the front group Gr1 and the inner lens surface of the rear group Gr2 must be 0.5 times or more the sum of the focal lengths of the front group Gr1 and the rear group Gr2. Preferably, it is desirable to be 0.7 times.

The rear group Gr2 arranges the principal rays having different scanning angles for the projected light ML from the second scanning device 50 so as to be parallel to or nearly parallel to the optical axis AX2, and the front group Gr1 arranges the projection light ML from the rear group Gr2. For the light projection ML, principal rays having different scanning angles are made to intersect at or near the pupil plane PS of the eye EY to be examined. That is, the projected light ML that has passed through the objective lens system 60 is condensed on the pupil plane PS (more precisely, the pupil) of the eye EY to be examined and projected onto the fundus EB. The projected light ML is in a collimated state or a nearly collimated state before entering the eye EY to be examined, but is brought into focus at the fundus EB after passing through the constituent elements of the eye EY to be examined, such as the lens and cornea.

The objective lens system 60 forms a turning point Q on the optical axis AX2 on the side of the eye to be inspected EY, at which the projected light ML that has passed through the first and second scanning devices 30 and 50 turns as a projected light flux by scanning. . The pivot point Q corresponds to the pupil plane PS or the pupil, and is formed on the optical axis AX2 of the objective lens system 60 and optically conjugate with the first and second scanning devices 30 and 50 . The projection light beams that have passed through the first and second scanning devices 30 and 50 pass through the objective lens system 60, and are irradiated onto the fundus EB via the turning point Q. As shown in FIG. That is, the principal ray of the projected light beam that has passed through the objective lens system 60 rotates about the rotation point Q as the first and second scanning devices 30 and 50 are operated, and the incident angle changes. As a result, the projected light flux is two-dimensionally scanned on the fundus EB. By aligning the fundus imaging system 100 with respect to the eye EY to be inspected, the projected light flux is converged on the pupil of the pupil plane PS and the turning point Q is placed within the pupil of the pupil plane PS. As a result, vignetting of the projected light flux and projected light ML is suppressed, and appropriate fundus observation or fundus photographing becomes possible.

The light receiving optical system 100b will be described below. In the light receiving optical system 100b, the reflected light RL reflected by the fundus oculi EB travels in the opposite direction to the central reflecting mirror 20 along the same optical path as that of the light projecting optical system 100a. That is, the reflected light RL from the fundus oculi EB passes through the objective lens system 60, the second scanning device 50, the scanning relay lens system 40, and the first scanning device 30, enters the central reflecting mirror 20, and passes through the transmitting portion of the central reflecting mirror 20. passes through and enters the light receiving section 70 . In the light-receiving optical system 100b, the reflected light RL from the fundus oculi EB is collimated by the objective lens system 60 in cooperation with elements of the eye to be examined EY, such as the crystalline lens, or in a state close to this state. The light travels backward along the same optical path as 100 a and enters the light receiving section 70 .

The light-receiving unit 70 of the light-receiving optical system 100b includes a red light-receiving sensor 71 having a light-receiving element for receiving red light contained in the reflected light RL, and a green light-receiving sensor having a light-receiving element for receiving green light contained in the reflected light RL. 72, a blue light receiving sensor 73 having a light receiving element for receiving blue light contained in the reflected light RL, a near infrared light receiving sensor 74 having a light receiving element for receiving near infrared light contained in the reflected light RL, 4 dichroic mirror 75, fifth dichroic mirror 76, sixth dichroic mirror 77, light receiving focus lens 78, light receiving lens 79, light receiving pinhole P2, visible light blocking member 91, photographing preparation light blocking member 92 , a first optical filter F1 and a second optical filter F2. The red light receiving sensor 71, the green light receiving sensor 72, and the blue light receiving sensor 73 of the light receiving unit 70 are light receivers for visible light for receiving visible reflected light from the fundus oculi EB or visible fluorescence excited by visible light. The element 70a is constructed. Here, visible fluorescence is not limited to visible fluorescence emitted by fluorescein, which is a contrast agent, but also includes visible autofluorescence mainly emitted by lipofuscin in the retinal pigment epithelium. The near-infrared light receiving sensor 74 constitutes an infrared light receiving element 70b for receiving near-infrared reflected light from the fundus EB or near-infrared fluorescence excited by the near-infrared light. The infrared light receiving element 70b may receive infrared reflected light or infrared fluorescence caused by infrared light other than near-infrared light. The light-receiving pinhole P2 becomes confocal in a conjugate relationship with the fundus EB. Condensing lenses 71a to 74a and light receiving pinholes 71b to 74b are arranged on the optical paths of the red light receiving sensor 71, the green light receiving sensor 72, the blue light receiving sensor 73, and the near-infrared light receiving sensor 74, respectively.

A portion of the reflected light RL (specifically, near-infrared light) from the fundus EB that has entered the light receiving unit 70 is reflected by the fourth dichroic mirror 75 and condensed by the condensing lens 74a to reach the light receiving pinhole. The reflected light RL that has passed through 74 b enters the near-infrared light receiving sensor 74 . Further, part of the reflected light RL (specifically, blue light) passes through the fourth dichroic mirror 75, is reflected by the fifth dichroic mirror 76, and is condensed by the condensing lens 73a into a light-receiving pinhole. The reflected light RL that has passed through 73 b enters the blue light receiving sensor 73 . Part of the reflected light RL (specifically, green light) passes through the fourth dichroic mirror 75 and the fifth dichroic mirror 76, is reflected by the sixth dichroic mirror 77, and is collected by the condenser lens 72a. The reflected light RL that has passed through the light receiving pinhole 72 b while being illuminated is incident on the green light receiving sensor 72 . Part of the reflected light RL (specifically, red light) passes through the fourth dichroic mirror 75, the fifth dichroic mirror 76, and the sixth dichroic mirror 77, and is condensed by the condensing lens 71a. The reflected light RL that has passed through the light receiving pinhole 71 b enters the red light receiving sensor 71 . The light-receiving pinholes 71b, 72b, 73b, and 74b are arranged in front of the light-receiving sensors 71, 72, 73, and 74, respectively. It is preferable to make the size optically larger than the pinhole P2.

In the light receiving unit 70, the light receiving pinholes 71b, 72b, 73b, and 74b are arranged at positions that are conjugate with the fundus EB of the eye EY to be examined. By guiding the reflected light RL to the light-receiving pinholes 71b, 72b, 73b, and 74b that are in a conjugate relationship with the eye to be examined EY, stray light, which is unnecessary light for measurement and is generated at a site away from the fundus EB, reaches the light-receiving pinhole 71b. , 72b, 73b, and 74b, so that a high-contrast fundus image can be captured.

The red light receiving sensor 71, the green light receiving sensor 72, and the blue light receiving sensor 73 are composed of, for example, band-pass filters and light receiving elements that cut wavelengths of the reflected light RL other than the light to be received. For example, a high-sensitivity photodiode or the like is used as the light receiving element. Brightness information can be obtained in the visible region for each point on the fundus EB by the light receiving sensors 71, 72, and 73. FIG. Based on the obtained luminance information (specifically, the output intensity of each of the light receiving sensors 71, 72, and 73) and the scanning position information of the first scanning device 30 and the second scanning device 50, a photographed image of the fundus oculi EB is obtained. can be formed by synthesizing the red photographed image data obtained by the red light receiving sensor 71, the green photographed image data obtained by the green light receiving sensor 72, and the blue photographed image data obtained by the blue light receiving sensor 73, Color image data can be generated by applying gamma processing or the like. In the visible autofluorescence photography mode using green light, the red photographed image data obtained by the red light receiving sensor 71 and the green photographed image data obtained by the green light receiving sensor 72 are combined and subjected to gamma processing or the like. Visible autofluorescence image data can be generated. In the visible autofluorescence imaging mode using blue light, gamma processing or the like can be applied to green photoimage data obtained by the green light receiving sensor 72 to generate visible autofluorescence image data. In the visible fluorescence photography mode using blue light, the green photography image data obtained by the green light receiving sensor 72 can be subjected to gamma processing or the like to generate visible fluorescence image data. Depending on the characteristics of the dichroic mirror, each light-receiving sensor can be constructed without providing a band-pass filter for cutting the wavelength band.

The near-infrared light receiving sensor 74 is composed of, for example, a band-pass filter that cuts a wavelength band other than the near-infrared light in the reflected light RL, and a light receiving element. For example, a high-sensitivity photodiode or the like is used as the light receiving element. The near-infrared light receiving sensor 74 can obtain luminance information in the near-infrared region for each point on the fundus EB. Based on the obtained luminance information (specifically, the output intensity of the near-infrared light receiving sensor 74) and the scanning position information of the first scanning device 30 and the second scanning device 50, a photographed image of the fundus EB is formed. can do. Depending on the characteristics of the dichroic mirror, the light receiving sensor can be constructed without providing the band-pass filter for cutting the wavelength band.

As described above, the captured image data of the fundus EB captured in the near-infrared range and the captured image data of the fundus EB captured in other wavelength ranges are stored in the storage unit 83 of the control device 80 or displayed on the monitor 201c. Although it is displayed, if a printer is provided, it can be printed.

The light receiving focus lens 78 is movable along the optical axis AX3 direction of the light receiving unit 70, and adjusts the focus of the reflected light RL from the fundus oculi EB. That is, by adjusting the position of the light-receiving focus lens 78, the focus deviation of the fundus observed image due to the diopter of the eye EY to be examined is corrected. Thereby, the position where the reflected light RL is condensed can be adjusted on each of the light receiving sensors 71-74. As already described, the light receiving focus lens 78 is linked with the operation of the light projecting focus lens 19 of the light projecting optical system 100a. The light-receiving pinhole P2 is provided between the light-receiving focus lens 78 and the light-receiving lens 79 and at a position conjugate with the fundus EB, and serves as a confocal diaphragm to remove unnecessary light from the reflected light RL. The reflected light RL that has passed through the light receiving focus lens 78 is focused on the opening of the light receiving pinhole P2 on the optical path and enters the light receiving lens 79 .

The visible light blocking member 91 is arranged on a common optical path for all wavelengths, specifically, a common light receiving optical path U1 for visible light and near-infrared light. In the example of FIGS. 2 and 3, the visible light shielding member 91 is composed of a front first visible light shielding member 91a and a rear second visible light shielding member 91b. The first visible light blocking member 91a is arranged on the optical axis AX3 between the light receiving focus lens 78 and the light receiving pinhole P2, and the second visible light blocking member 91b is arranged between the light receiving pinhole P2 and the light receiving lens 79. is arranged on the optical axis AX3. The first visible light shielding member 91 a and the second visible light shielding member 91 b remove harmful light (unnecessary light) generated by reflection on the lens surfaces of the front group Gr<b>1 or the rear group Gr<b>2 of the objective lens system 60 . The first visible light shielding member 91a positioned on the side of the subject's eye EY with respect to the light-receiving pinhole P2 serves mainly for shielding harmful light generated in the front group Gr1, and is located on the side opposite to the subject's eye EY with respect to the light-receiving pinhole P2. The second visible light shielding member 91b positioned at is useful for shielding harmful light mainly generated in the rear group Gr2. In the present embodiment, the fundus imaging system 100 is configured so that the fundus conjugate plane EC is located on the inner lens surface of the front group Gr1 and the rear group Gr2 when the diopter correction range of the subject's eye EY is ±25 diopters. Designed not to come close. Therefore, in the diopter correction range of ±25 diopters, the blocking of the harmful light described above is effective. The size or diameter of the first and second visible light shielding members 91a and 91b is determined in consideration of the balance between the effect of shielding harmful light and the shielding (sacrificing) of the reflected light RL from the fundus oculi EB. .

As shown in FIG. 3, the visible light blocking member 91 has a common light receiving optical path U1 between a blocking position A1 that locally blocks harmful light and a non-blocking position A2 that blocks a lower degree of blocking than the blocking position A1. It is configured to be movable along the optical axis AX3. Here, the light shielding position A1 means a position in which harmful light of visible wavelength or near-infrared wavelength is shielded. The non-light shielding position A2 means a position where the visible light shielding member 91 is displaced from the harmful light shielding position and the light shielding function is lower than that of the light shielding position A1 to increase the light amount of the observation light. The visible light shielding member 91 is configured such that the light shielding portion is locally arranged in the optical path of the harmful light at the light shielding position A1. At the non-light shielding position A2, the ratio of the area of the light shielding portion of the visible light shielding member 91 to the beam diameter decreases. Also, the visible light shielding member 91 is arranged on the light receiving optical path U1 at the non-shielding position A2. The harmful light is visible light or near-infrared light reflected by the objective lens system 60 or the like. The visible light blocking member 91 partially blocks not only harmful light but also visible light or near-infrared light reflected by the fundus EB and visible fluorescence or infrared fluorescence from the fundus EB. The visible light shielding member 91 is set in a moving mechanism 93, and its movement is controlled by a driving section 82 of a control device 80, which is a control section. The moving mechanism 93 is, for example, a slide moving mechanism using a stepping motor or the like, but is not limited to this. The visible light shielding member 91 is arranged at an appropriate position of the shielding position A1 or the non-shielding position A2 corresponding to the operation mode of the fundus imaging device 200 by movement control under the control of the control device 80 . The fundus imaging system 100 focuses by moving the light receiving focus lens 78 in the direction of the optical axis AX3 in accordance with the diopter of the eye EY to be examined. A visible light shielding member 91 is arranged at the shielding position A1 corresponding to the diopter. The visible light shielding member 91 has its shielding position A1 on the optical path changed according to the diopter of the eye EY to be inspected in the color photographing mode. Accordingly, for example, in a color photographing mode using visible light, the visible light shielding member 91 can be arranged at the light shielding position A1, which is a position suitable for shielding according to the diopter of the subject's eye EY, in accordance with the diopter correction. can. In the example of FIG. 2, as the diopter of the subject's eye EY becomes negative (myopia), the first visible light blocking member 91a moves closer to the light receiving pinhole P2, and the second visible light blocking member 91b moves closer to the light receiving pinhole P2. Move away from P2. On the other hand, as the diopter of the subject's eye EY becomes positive (hyperopia), the first visible light blocking member 91a moves away from the light receiving pinhole P2, and the second visible light blocking member 91b moves toward the light receiving pinhole P2. move to The visible light shielding member 91 changes its position in the direction along the optical axis AX3 according to the diopter of the subject's eye EY as described above in the color imaging mode, and is fixed at the shielding position A1 during color imaging. Although the details will be described later, in each fluorescence imaging mode, the visible light shielding member 91 does not need to shield the visible light. move. In the fundus observation mode, the visible light shielding member 91 may be placed at the light shielding position A1 if the required amount of observation light can be ensured in combination with the photographing preparation light shielding member 92, which will be described later.

In this embodiment, the imaging preparation light shielding member 92 is arranged on the optical path of the near-infrared wavelength, specifically, on the light-receiving optical path U2 dedicated to the near-infrared light. Two or one imaging preparation light shielding members 92 are provided in the diopter range of the subject's eye EY. In the example of FIGS. 2 and 3, the photographing preparation light shielding member 92 is composed of a front first photographing preparation light shielding member 92a and a rear second photographing preparation light shielding member 92b. The first photographing preparation light shielding member 92a and the second photographing preparation light shielding member 92b remove harmful near-infrared light generated by reflection on the lens surface of the front group Gr1 or the rear group Gr2 of the objective lens system 60. FIG. The first photographing preparation light shielding member 92a positioned on the side of the condenser lens 74a mainly serves to shield harmful near-infrared light generated in the rear group Gr2, and the second photographing preparation light shielding member positioned on the light receiving pinhole 74b side. 92b serves mainly for shielding harmful near-infrared light generated in the front group Gr1. Regarding the light shielding size or diameter of the first and second imaging preparation light shielding members 92a and 92b, the balance between the effect of shielding harmful light and the shielding (sacrificing) of the reflected light RL of the near-infrared light from the fundus oculi EB is taken into account. Decide after consideration. In this embodiment, the shielding of the reflected light RL from the fundus oculi EB is minimized instead of completely shielding the harmful light. The imaging preparation light shielding member 92 is configured to exert a light shielding function on the optical path mainly during image detection with near-infrared light before fluorescence imaging, and therefore may have a lower light shielding accuracy than the visible light shielding member 91 .

As shown in FIG. 3, the photographing preparation light shielding member 92 is configured to be movable between a light shielding position B1 that locally shields harmful light and a non-light shielding position B2 that has a lower degree of light shielding than the light shielding position B1. . Here, the shielding position B1 means a position in which harmful light of near-infrared wavelength is shielded. The non-light shielding position B2 means a position where the photographing preparation light shielding member 92 is shifted from the harmful light shielding position and the light shielding function is lower than that of the light shielding position B1 to increase the amount of detected light. At the non-light-shielding position B2, if there is no barrier filter for near-infrared fluorescence (first optical filter F1 to be described later), harmful light of near-infrared wavelengths is allowed to pass. The photographing preparation light-shielding member 92 has a light-shielding portion located locally in the optical path of the harmful light at the light-shielding position B1. At the non-light-shielding position B2, the ratio of the area of the light-shielding portion of the imaging preparation light-shielding member 92 to the beam diameter decreases. Further, the photographing preparation light blocking member 92 may be arranged on the light receiving optical path U2 or may be arranged outside the light receiving optical path U2 at the non-light blocking position B2. The imaging preparation light shielding member 92 partially shields not only harmful light but also near-infrared light reflected by the fundus EB and infrared fluorescence from the fundus EB. The photographing preparation light shielding member 92 is set in a moving mechanism 94, and its movement is controlled by a driving section 82 of a control device 80, which is a control section. The moving mechanism 94 is, for example, a slide moving mechanism using a motor or the like, but is not limited to this. The movement control under the control of the control device 80 places the imaging preparation light shielding member 92 at an appropriate position, either the light shielding position B1 or the non-light shielding position B2, corresponding to the operation mode of the fundus imaging device 200 . The photographing preparation light shielding member 92 is arranged at the light shielding position B1, which is the light shielding position, during image detection before photographing in each fluorescence photographing mode. On the other hand, during fluorescence imaging, the imaging preparation light blocking member 92 moves to the non-light blocking position B2, which is the non-light blocking position. The imaging preparation light shielding member 92 may always be arranged at the light shielding position B1, which is the light shielding position, in the fundus observation mode, the color imaging mode, the visible spontaneous fluorescence imaging mode, and the visible fluorescence imaging mode.

The first photographing preparation light shielding member 92a is inserted into and removed from the optical path U2 dedicated to near-infrared light, specifically, between the condenser lens 74a leading to the near-infrared light receiving sensor 74 and the light receiving pinhole 74b. possible. The first photographing preparation light shielding member 92a moves in the direction perpendicular to the light path between the light shielding position B1 and the non-light shielding position B2 while the position on the light receiving optical path U2 is fixed.

The second photographing preparation light shielding member 92b is provided along the light receiving optical path U2 dedicated to near-infrared light, specifically, between the condenser lens 74a leading to the near-infrared light receiving sensor 74 and the light receiving pinhole 74b. It is provided movably. The second photographing preparation light shielding member 92b is arranged between the front first photographing preparation light shielding member 92a and the light receiving pinhole 74b. The second photographing preparation light shielding member 92b is variable in its position on the light receiving optical path U2, and moves along the light path between the light shielding position B1 and the non-light shielding position B2.

The moving time of the photographing preparation light blocking member 92 from the light blocking position B1 to the non-light blocking position B2 is shorter than the moving time of the visible light blocking member 91 from the light blocking position A1 to the non-light blocking position A2. The imaging preparation light-shielding member 92 that quickly switches between the light-shielding position B1 and the non-light-shielding position B2 can shorten the light amount adjustment time between infrared observation using near-infrared light and fluorescence observation or fluorescence imaging.

The relationship between the visible light shielding member 91 and the photographing preparation light shielding member 92 will be described below. The visible light shielding member 91 is placed at the shielding position A1 when observing the fundus by alignment or the like in the near-infrared fluorescence imaging mode, for example, so that the harmful light that causes bright spots to appear in the observed fundus image. can be blocked. On the other hand, when capturing a near-infrared fluorescence image, the harmful light is removed by the first optical filter F1, which is a barrier filter for infrared fluorescence inserted at the time of capturing. When the visible light shielding member 91 is at the shielding position A1, the amount of light required for good photographing is reduced. The amount of light can be ensured by moving the visible light shielding member 91 from the light shielding position A1 to a position that does not affect fluorescence imaging at the moment of infrared fluorescence imaging, or by retracting it from the optical path. The mechanism to make it becomes complicated. Further, if the visible light shielding member 91 is retracted from the shielding position A1 in advance when detecting an image before photographing, the observation image of the fundus oculi becomes difficult to see due to harmful light. Therefore, the visible light shielding member 91 is moved to the non-shielding position A2 in advance during image detection before photographing, and harmful light is shielded during image detection by the separately provided photographing preparation light shielding member 92 . Since the imaging preparation light shielding member 92 is used only during image detection and is less likely to affect fluorescence imaging, the imaging preparation light shielding member 92 is configured not to move at a position on the optical axis AX3 according to the diopter of the subject's eye EY. ing. The photographing preparation light shielding member 92 is momentarily removed only at the time of photographing. By adopting a configuration in which the photographing preparation light shielding member 92 is moved in one direction from the optical path, the switching mechanism can be simplified. It should be noted that, depending on the design of the visible light shielding member 91, the photographing preparation light shielding member 92 may not be necessary during color photography.

The first optical filter F1 is a barrier filter that selectively transmits infrared fluorescence excited by near-infrared light. The first optical filter F1 selectively transmits infrared fluorescence with a wavelength of 830 nm excited by near-infrared light with a wavelength of 760 nm emitted from the near-infrared laser 14, for example, and emits it to the near-infrared light receiving sensor 74 side. Let The first optical filter F1 is detachably provided in the light receiving optical path U2 for near-infrared light, and is inserted in the light receiving optical path U2 for near-infrared light only when capturing a near-infrared fluorescence image. In the example of FIG. 2, the first optical filter F1 is arranged between the fourth dichroic mirror 75 and the condenser lens 74a. Although illustration is omitted, the first optical filter F1 is set in a switching mechanism (not shown), and is switched and controlled by a driving section 82 of a control device 80, which is a control section.

The second optical filter F2 is a barrier filter that selectively transmits visible light, specifically visible fluorescence excited by green light or blue light. The second optical filter F2 is detachably provided in the light receiving optical path U3 for visible light, and is inserted in the light receiving optical path U3 for visible light only when capturing an autofluorescence image or when capturing a visible fluorescence image. In the example of FIG. 2, the second optical filter F2 is arranged between the fourth dichroic mirror 75 and the fifth dichroic mirror . The second optical filter F2 is configured to be switchable between the green optical filter F2a and the blue optical filter F2b. The optical filter for green F2a transmits only the fluorescence wavelength for visible autofluorescence image capturing with green light in the autofluorescence image capturing mode with green light. The optical filter for blue F2b transmits only the fluorescence wavelength for visible autofluorescence imaging with blue light or the fluorescence wavelength for visible fluorescence imaging in the autofluorescence imaging mode or visible fluorescence imaging mode using blue light. Although illustration is omitted, the second optical filter F2 is set in a switching mechanism (not shown), and is switched and controlled by a driving section 82 of a control device 80, which is a control section.

The control device 80 has an electronic circuit or the like that performs control processing of each part of the fundus imaging device 200 and arithmetic processing. The control device 80 has a processing section (CPU: Central Processing Unit) 81 , a driving section 82 , a storage section 83 and an image generating section 84 . The control device 80 is also provided with an input unit 85 and the like.

The processing unit 81 comprehensively controls the driving unit 82, the storage unit 83, the image generation unit 84, and the like. The drive unit 82 controls the operations of the lasers 11 to 14, the light receiving sensors 71 to 74, the first and second scanning devices 30 and 50, and changes the traveling direction of the projected light ML. Further, the driving unit 82 controls the operation of adjusting the arrangement of the light projecting lens 18 and the light projecting focus lens 19, the light receiving focus lens 78 and the light receiving lens 79, and the focus of the light projecting optical system 100a and the light receiving optical system 100b is controlled by the operator. or automatic focus detection. Further, the drive unit 82 controls the operation of adjusting the arrangement of the visible light shielding member 91, the photographing preparation light shielding member 92, the first optical filter F1, and the second optical filter F2. The drive unit 82 controls the operating state of the drive mechanism 302 under the operation of the operator or the control of the processing unit 81, and arranges the fundus imaging system 100 at a three-dimensional appropriate position with respect to the eye EY to be examined. be able to. The storage unit 83 stores control programs for each unit, fixed data, temporary data, and the like. Further, the storage unit 83 stores image data obtained by the light receiving sensors 71 to 74 and combined data thereof, and stores alignment information obtained by adding additional information to the image data obtained by the light receiving sensors 71 to 74 . The image generator 84 generates received light signal color image data output from the light receiving sensors 71-74. In addition, the image generator 84 generates color image data and visible autofluorescence image data by synthesizing the image data of each color acquired by the light receiving sensors 71 to 73 corresponding to visible light. The monitor 201c displays information to be presented to the operator, generated fundus image data, alignment state, and the like. The input unit 85 operates in cooperation with the operation unit 205i shown in FIG. 1, and allows the operator to set each unit of the fundus imaging device 200, switch the fundus imaging mode, and perform alignment and focus adjustment. It enables setting, operation, etc.

As shown in FIG. 4A, before the photographing mode is selected, the visible light shielding member 91 and the photographing preparation light shielding member 92 are arranged at the light shielding positions A1 and B1 on the light receiving optical paths U1 and U2, respectively. The first and second optical filters F1, F2 are retracted from the light receiving optical paths U2, U3. When the infrared fluorescence imaging mode is selected, the controller 80 sets the first optical filter F1 out of the near-infrared light receiving optical path U2 during image detection before imaging, as shown in FIG. 4B. Then, the visible light shielding member 91 is moved from the light shielding position A1 to the non-light shielding position A2, and the photographing preparation light shielding member 92 is placed at the light shielding position B1. After that, when the infrared fluorescence imaging trigger is recognized, the control device 80 inserts the first optical filter F1 into the near-infrared light receiving optical path U2 as shown in FIG. Control is performed to move the light blocking member 92 from the light blocking position B1 to the non-light blocking position B2. As a result, during image detection before photographing in the infrared fluorescence photographing mode, the visible light shielding member 91 is retracted to the non-shielding position A2, and harmful light is removed by the photographing preparation light shielding member 92 at the light shielding position B1. It is possible to obtain a clear (clear) infrared fundus image. Further, during infrared fluorescence photography, the photographing preparation light blocking member 92 is retracted to the non-light blocking position B2, harmful light is removed using only the first optical filter F1, and the amount of light necessary for good image photography is sufficiently obtained. By ensuring this, a clean (clear) and bright fluorescent image can be obtained.

Further, when the visible fluorescence imaging mode or the visible autofluorescence imaging mode is selected, the control device 80 causes the second optical filter F2 to set the light receiving optical path of visible light during image detection before imaging, as shown in FIG. 4B. In a state out of U3, the visible light blocking member 91 is moved from the blocking position A1 to the non-blocking position A2, and control is performed to place the photographing preparation blocking member 92 at the blocking position B1. Thereafter, when the visible fluorescence imaging trigger is recognized, the control device 80 inserts the second optical filter F2 into the visible light receiving optical path U3 as shown in FIG. 5B. As a result, when detecting an image before photographing in a visible fluorescence photographing mode or the like, after retracting the visible light shielding member 91 to the non-shielding position A2, harmful light is removed by the photographing preparation light shielding member 92 at the light shielding position B1. It is possible to obtain a clear (clear) infrared fundus image. Further, during visible fluorescence imaging, the imaging preparation light shielding member 92 disposed outside the visible light receiving optical path U3 does not affect the visible light receiving optical path U3, and only the first optical filter F1 is used to filter out harmful light. A clean (clear) and bright fluorescence image can be obtained by removing the light and securing a sufficient amount of light necessary for taking a good image.

In this embodiment, the second optical filter F2 is inserted into the light receiving optical path U3 after the imaging trigger is recognized. However, unlike this embodiment, the second optical filter F2 may be inserted into the light receiving optical path U3 before the imaging trigger is recognized.

The fundus photographing by the fundus photographing device 200 will be described below with reference to FIG. 6 and the like.

<Initial alignment (normal infrared fundus observation mode)>
First, an initial alignment of the fundus observation image is performed in the fundus observation mode under the control of the control device 80 (step S01). In the initial alignment, auto-alignment is performed to three-dimensionally position the fundus imaging system 100 in the XYZ directions during fundus observation. The fundus imaging system 100 is operated under the control of the control device 80, and the fundus image for alignment obtained by the fundus imaging system 100 is displayed as a moving image on the monitor 201c. Align with Note that focus adjustment may be performed in the initial alignment. In the infrared fundus observation mode before the photographing mode is selected, the visible light shielding member 91 and the photographing preparation light shielding member 92 are arranged at the light shielding positions A1 and B1 on the light receiving optical paths U1 and U2, respectively. The two optical filters F1 and F2 are retracted from the light receiving optical paths U2 and U3 (see FIG. 4A). If the amount of observation light is insufficient, the visible light shielding member 91 or the photographing preparation light shielding member 92 may be retracted from the optical path.

<Mode selection for shooting>
Next, under the control of the control device 80, the operator operates the operation unit 205i through the input unit 85 to select the fundus photographing mode (step S11). The selected fundus photographing mode is recorded in the storage unit 83 . In the mode selection, a desired mode is selected from color photography mode, visible autofluorescence photography mode, visible fluorescence photography mode, and near-infrared fluorescence photography mode. In the visible autofluorescence imaging mode, the light source used for imaging is further selected from green light and blue light. In the visible fluorescence photography mode and the near-infrared fluorescence photography mode, one-frame photography or moving image photography is selected. When the control device 80 recognizes the selection of the infrared fluorescence imaging mode, the visible spontaneous fluorescence imaging mode, and the visible fluorescence imaging mode, it moves the visible light shielding member 91 to the non-shielding position A2. At this time, the photographing preparation light shielding member 92 remains arranged at the light shielding position B1 (see FIG. 4B). When the control device 80 recognizes the selection of the color photographing mode, the control device 80 keeps the visible light blocking member 91 at the blocking position A1. In the color photographing mode, when the amount of observation light is insufficient when the visible light shielding member 91 and the photographing preparation light shielding member 92 are used together for the next alignment and focus adjustment, the photographing preparation light shielding member 92 is placed in the optical path. may be evacuated from

When the visible autofluorescence imaging mode is selected and green light is selected as the light source used, the green optical filter F2a (second optical filter F2) is inserted between the fourth dichroic mirror 75 and the fifth dichroic mirror 76. Further, when blue light is selected as the light source to be used, a blue optical filter F2b (second optical filter F2) is inserted. When the visible fluorescence imaging mode is selected, the blue optical filter F2b is inserted between the fourth dichroic mirror 75 and the fifth dichroic mirror . When the near-infrared fluorescence imaging mode is selected, the first optical filter F1 is inserted between the fourth dichroic mirror 75 and the condenser lens 74a. Although the first optical filter F1 is inserted after recognition of the shooting trigger, the second optical filter F2 may be inserted before recognition of the shooting trigger.

<Alignment and focus adjustment (infrared fundus observation mode before photographing)>
Next, under the control of the control device 80, alignment and focus adjustment of the fundus observation image are performed (step S21). During alignment and focus adjustment, near-infrared light is emitted from the near-infrared laser 14 while the first scanning device 30 and the second scanning device 50 are continuously scanning, and a near-infrared fundus observation image is monitored. 201c is displayed live. Alignment and focus adjustment of the fundus oculi observation image may be performed manually by the operator using the operation unit 205i, or may be automated under the control of the control device 80. FIG. Alignment and focus adjustment may be performed simultaneously with each image capturing mode described later, or may be omitted.

After confirming the alignment state manually or automatically, the operator presses a photographing button (not shown) constituting the operation unit 205i to select the above mode from the state of alignment and focus adjustment under the control of the control device 80. Switching to the selected shooting mode is performed.

<Color shooting mode>
In the color photographing mode, under the control of the control device 80, the fundus EB is irradiated with red light, green light, and blue light at the same time, and the reflected light RL of each color is received at the same time for photographing. The control device 80 generates color image data by synthesizing the obtained red photographed image data, green photographed image data, and blue photographed image data.

The control device 80 keeps the visible light shielding member 91 at the shielding position A1 even after recognizing the photographing trigger.

When the shooting button of the operation unit 205i is pressed so as to shift to the selected shooting mode, the continuous scanning of the second scanning device 50 is temporarily stopped and the second scanning device 50 moves to the shooting start position. Next, the near-infrared laser 14 is turned off, the red laser 11, the green laser 12, and the blue laser 13 are turned on at the same time, the second scanning device 50 is operated again, and color image capturing is started ( step S31). In one shooting of a color image, for example, image data of 3000×3000 pixels are simultaneously obtained for each of red light, green light, and blue light by vertical scanning for 0.4 seconds. The obtained red fundus image data, green fundus image data, and blue fundus image data are synthesized by the image generator 84 of the control device 80, and gamma processing or the like is performed to generate color image data (step S32). The generated color image data is stored in the storage unit 83 (step S71) and displayed on the monitor 201c (step S81).

When the color image is captured, the red laser 11, the green laser 12, and the blue laser 13 are turned off, and the driving of the first scanning device 30 and the second scanning device 50 is stopped (step S91).

<Near-infrared fluorescence photography mode>
In the near-infrared fluorescence imaging mode, under the control of the control device 80, the fundus EB is irradiated with near-infrared light, and the reflected light RL is received and photographed. The controller 80 generates near-infrared fluorescence image data from the obtained near-infrared photographed image data.

A contrast agent (indocyanine green (ICG)) is injected into the subject prior to infrared fluorescence imaging. It takes about 10 seconds after the injection of the contrast medium until it reaches the fundus EB.

In the near-infrared fluorescence photography mode, the first optical filter F1 is retracted from the light receiving optical path U2 of the near-infrared light during image detection before photography, and the photography preparation light blocking member 92 is arranged at the light blocking position B1. After recognizing the imaging trigger, the control device 80 inserts the first optical filter F1 into the light receiving optical path U2. At this time, the control device 80 operates the moving mechanism 93 to move the photographing preparation light blocking member 92 from the light blocking position B1 to the non-light blocking position B2 (see FIG. 5A).

When the photographing button of the operation unit 205i is pressed so as to shift to the selected photographing mode, the first optical filter F1 is inserted, the continuous scanning of the second scanning device 50 is temporarily stopped, and the second scanning device 50 moves to the shooting start position. Next, the output of the near-infrared laser 14 is increased, the second scanning device 50 is operated again, and capturing of the near-infrared fluorescence image is started (step S41). In the case of capturing a near-infrared fluorescence image once, for example, image data of 3000×3000 pixels are obtained by vertical scanning for 0.4 seconds. In the case of continuous shooting, for example, 10 vertical scans are performed per second, and image data of 700×700 pixels are obtained for each scan. The image generating unit 84 of the control device 80 performs gamma processing or the like on the obtained near-infrared fundus image data to generate near-infrared fluorescence image data (step S42). The generated near-infrared fluorescence image data is stored in the storage unit 83 (step S71) and displayed on the monitor 201c (step S81).

After the near-infrared fluorescence image is captured, the near-infrared laser 14 is turned off, and the driving of the first scanning device 30 and the second scanning device 50 is stopped (step S91).

<Visible autofluorescence photography mode (FAF: fundus autofluorescence)>
In the visible autofluorescence photographing mode, under the control of the control device 80, light from a light source selected in mode selection from among green light and blue light is applied to the fundus EB, and the reflected light RL is received and photographed. In the case of green light, the control device 80 generates visible autofluorescence image data by synthesizing the obtained red-captured image data and green-captured image data. In the case of blue light, the controller 80 generates visible autofluorescence image data from the obtained green captured image data.

In the visible spontaneous fluorescence photographing mode, the photographing preparation light shielding member 92 is arranged at the light shielding position B1 with the second optical filter F2 retracted from the light receiving optical path U3 of the visible light during image detection before photographing. After recognizing the imaging trigger, the control device 80 inserts the second optical filter F2 into the light receiving optical path U3 (see FIG. 5B). At this time, the photographing preparation light shielding member 92 that is not on the light receiving optical path U3 of the visible light may remain arranged at the light shielding position B1.

When the shooting button of the operation unit 205i is pressed so as to shift to the selected shooting mode, the second optical filter F2 is inserted, the continuous scanning of the second scanning device 50 is temporarily stopped, and the second scanning device 50 moves to the shooting start position. Next, the near-infrared laser 14 is turned off, the selected green laser 12 or blue laser 13 is turned on, the second scanning device 50 is operated again, and the photographing of the autofluorescent fundus image is started (step S51). For one photographing of the autofluorescent fundus image, for example, image data of 3000×3000 pixels are acquired by vertical scanning for 0.4 seconds. In the case of green light, the image generating unit 84 of the control device 80 synthesizes the obtained red fundus image data and green fundus image data, and performs gamma processing or the like to generate autofluorescent fundus image data (step S52). In the case of blue light, gamma processing or the like is performed on the obtained green fundus image data to generate autofluorescent fundus image data (step S52). The generated autofluorescent fundus image data is stored in the storage unit 83 (step S71) and displayed on the monitor 201c (step S81).

When the visible autofluorescence image is captured, the green laser 12 and blue laser 13 are turned off, and the driving of the first scanning device 30 and the second scanning device 50 is stopped (step S91).

<Visible fluorescence photography mode (FAG: fluorescein angiography)>
In the visible fluorescence imaging mode, under the control of the control device 80, the fundus oculi EB is irradiated with blue light, and the reflected light RL is received for imaging. The controller 80 generates visible fluorescence image data from the obtained green photographed image data.

For visible fluorescence imaging, a contrast medium (fluorescein) is injected into the subject prior to visible fluorescence imaging. It takes about 10 seconds after the injection of the contrast medium until it reaches the fundus EB.

In the visible fluorescence photographing mode, the photographing preparation light shielding member 92 is arranged at the light shielding position B1 with the second optical filter F2 retracted from the light receiving optical path U3 of the visible light during image detection before photographing. After recognizing the imaging trigger, the control device 80 inserts the second optical filter F2 into the light receiving optical path U3 (see FIG. 5B). At this time, the photographing preparation light shielding member 92 that is not on the light receiving optical path U3 of the visible light may remain arranged at the light shielding position B1.

When the shooting button of the operation unit 205i is pressed so as to shift to the selected shooting mode, the second optical filter F2 is inserted, the controller 80 temporarily stops the continuous scanning of the second scanning device 50, The second scanning device 50 moves to the imaging start position. Next, in the case of capturing a visible fluorescence image once, the near-infrared laser 14 is turned off, the blue laser 13 is turned on, the second scanning device 50 operates again, and the visible fluorescence image capturing is started. (Step S61). For example, image data of 3000×3000 pixels are obtained by vertical scanning for 0.4 seconds. In the case of continuous imaging, the blue laser 13 is turned on while the near-infrared laser 14 is kept turned on, the second scanning device 50 is operated again, and the near-infrared fundus image and visible fluorescence image for alignment are started to be photographed. (step S61). For example, vertical scanning is performed 10 times per second, and image data of 700×700 pixels is acquired per scanning. The image generating unit 84 of the control device 80 performs gamma processing or the like on the obtained green fundus image data to generate visible fluorescence image data (step S62). In the case of continuous photography, near-infrared fundus image data is also generated (step S62). The generated visible fluorescence image data and near-infrared fundus image data are stored in the storage unit 83 (step S71) and displayed on the monitor 201c (step S81).

After the visible fluorescence image is captured, the blue laser 13 is turned off. In the case of continuous photographing, the driving of the first scanning device 30 and the second scanning device 50 is stopped after the near-infrared laser 14 is also turned off (step S91).

The fundus imaging apparatus 200 described above includes the imaging preparation light shielding member 92 and the first optical filter F1. The optical filter F1 is configured to be insertable/removable in the light receiving optical path U2, and the photographing preparation light shielding member 92 and the first optical filter F1 are appropriately arranged corresponding to each operation of infrared observation, infrared fluorescence observation, and infrared fluorescence photographing. By changing, the amount of reflected infrared light or infrared fluorescent light can be appropriately adjusted. Accordingly, it is possible to obtain a good image corresponding to each motion.

[Second embodiment]
A fundus imaging apparatus according to the second embodiment will be described below. Note that the fundus imaging apparatus of the second embodiment is a modification of the fundus imaging apparatus of the first embodiment, and items that are not particularly described are the same as those of the first embodiment.

As shown in FIG. 7, in the present embodiment, the photographing preparation light shielding member 92 is provided as a third photographing preparation light shielding member 95 so as to be insertable and removable in a common light receiving optical path U1 common to visible light and near-infrared light. ing. The third photographing preparation light blocking member 95 moves in the direction perpendicular to the optical path between the light blocking position B1 and the non-light blocking position B2 while the position on the common light receiving optical path U1 is fixed. The visible light shielding member 91 and the third photographing preparation light shielding member 95 are arranged so as not to interfere with each other. In the example of FIG. 7, the third photographing preparation light shielding member 95 is arranged between the first visible light shielding member 91a and the second visible light shielding member 91b. It is composed of a 3-1 light blocking member 95a on the side of the light blocking member 91a and a 3-2 light blocking member 95b on the side of the second visible light blocking member 91b.

The arrangement of each member in each imaging mode of the fundus imaging apparatus 200 of this embodiment will be described below.

<Initial alignment (normal infrared fundus observation mode)>
In the infrared fundus observation mode, which is before the photographing mode is selected, the visible light shielding member 91 is arranged at the shielding position A1 on the light receiving optical path U1, and the photographing preparation light shielding member 92, that is, the third photographing preparation light shielding member 95 is positioned at the light shielding position A1. , and the first and second optical filters F1 and F2 are retracted from the light receiving optical paths U2 and U3 (see FIG. 8A).

<Mode selection for shooting>
When the controller 80 recognizes the selection of the infrared fluorescence imaging mode, the visible spontaneous fluorescence imaging mode, and the visible fluorescence imaging mode, the control device 80 moves the visible light shielding member 91 to the non-shielding position A2 for image detection before imaging, The photographing preparation light shielding member 92, that is, the third photographing preparation light shielding member 95 is moved to the light shielding position B1 (see FIG. 8B). When the control device 80 recognizes that the color photographing mode has been selected, the control device 80 keeps the visible light blocking member 91 at the blocking position A1.

<Color shooting mode>
The control device 80 keeps the visible light shielding member 91 at the shielding position A1 even after recognizing the photographing trigger.

<Near-infrared fluorescence photography mode>
In the near-infrared fluorescence photography mode, the first optical filter F1 is retracted from the light receiving optical path U2 of the near-infrared light during image detection before photography, and the photography preparation light blocking member 92 is arranged at the light blocking position B1. After recognizing the imaging trigger, the control device 80 inserts the first optical filter F1 into the light receiving optical path U2. At this time, the control device 80 operates a moving mechanism (not shown) to move the photographing preparation light blocking member 92 from the light blocking position B1 to the non-light blocking position B2 (see FIG. 9A).

<Visible autofluorescence photography mode>
In the visible spontaneous fluorescence photographing mode, the photographing preparation light shielding member 92 is arranged at the light shielding position B1 with the second optical filter F2 retracted from the light receiving optical path U3 of the visible light during image detection before photographing. After recognizing the shooting trigger, the control device 80 inserts the second optical filter F2 into the light receiving optical path U3 (see FIG. 9B). At this time, the control device 80 operates a moving mechanism (not shown) to move the photographing preparation light blocking member 92 from the light blocking position B1 to the non-light blocking position B2 (see FIG. 9B).

<Visible fluorescence photography mode>
In the visible fluorescence photographing mode, the photographing preparation light shielding member 92 is arranged at the light shielding position B1 with the second optical filter F2 retracted from the light receiving optical path U3 of the visible light during image detection before photographing. After recognizing the shooting trigger, the control device 80 inserts the second optical filter F2 into the light receiving optical path U3 (see FIG. 9B). At this time, the control device 80 operates a moving mechanism (not shown) to move the photographing preparation light blocking member 92 from the light blocking position B1 to the non-light blocking position B2 (see FIG. 9B).

As described above, the present invention has been described in accordance with the embodiments, but the present invention is not limited to the above-described embodiments and the like. For example, although the photographing preparation light shielding member 92 is composed of two light shielding members 92a and 92b (or light shielding members 95a and 95b), one of the light shielding members 92a and 92b (or light shielding members 95a and 95b) is omitted. It may be composed of one light shielding member. Also, the visible light shielding member 91 may be configured by one shielding member according to the configuration of the objective lens system 60 .

In the above embodiment, the fundus imaging apparatus uses the visible light source 10a and the infrared light source 10b, but the fundus imaging apparatus may use the visible light source 10a and the infrared light source 10b independently. For example, as shown in FIG. 10, in the case of a fundus imaging apparatus using only the visible light source 10a, a visible light shielding member 91 is provided in the light receiving optical path U4 so as to be movable along the optical path, and an imaging preparation light shielding member 96 is inserted into the optical path. It is configured to be detachable. The photographing preparation light shielding member 96 corresponds to the photographing preparation light shielding member described in the second embodiment, and is composed of two light shielding members 96a and 96b. After the fluorescence photography mode is selected, the visible light shielding member 91 is arranged at the non-shielding position A2, and the photographing preparation light shielding member 96 is arranged at the shielding position B1 during image detection before photographing. After the control device 80 recognizes the fluorescence imaging trigger, the second optical filter F2 is inserted, and the imaging preparation light blocking member 96 is moved to the non-light blocking position B2.

In the above embodiment, in the color photographing mode and the fundus observation mode, the photographing preparation light shielding member 92 may be at the light shielding position B1 or at the non-light shielding position B2.

In the above embodiment, the lens configuration shown in FIG. 2 is an example of the objective lens system 60, and various lens configurations are possible.

In the above embodiment, the configurations of the light source unit 10, the first scanning device 30, the second scanning device 50, the light receiving unit 70, and the like illustrated in FIG. 2 are merely examples, and can be changed as appropriate.

In the above-described embodiment, the light source unit 10 of the fundus imaging device 200 is composed of four-wavelength lasers, but the number and combination of wavelengths can be changed as appropriate. Further, although the light source unit 10 is configured with a laser, it may be configured with an LED (light emitting diode).

In the above embodiment, a polygon mirror is used as the first scanning device 30 and a galvanometer mirror is used as the second scanning device 50, but other scanning devices such as a resonant scanner and a MEMS mirror may be used.

In the above-described embodiment, in addition to the fundus imaging system 100, another optical system such as an anterior segment observation system provided around the objective lens system 60 is separately provided, and alignment using an anterior segment observation image is performed at the initial stage. It may be used together at the time of alignment.

In the above embodiment, in each operation mode, the brightness of the fundus image may be adjusted by inserting an ND filter or switching between a plurality of ND filters in order to facilitate observation and detection.

11, 12, 13, 14... Laser 10... Light source unit 10a... Visible light source 10b... Infrared light source 15, 16, 17, 75, 76, 77... Dichroic mirror 18... Projection lens 19... Projection Optical focus lens 20... Central reflecting mirror 30, 50... Scanning device 40... Scanning relay lens system 60... Objective lens system 70... Light receiving part 70a... Light receiving element for visible light 70b... Light receiving for infrared light Elements 71, 72, 73, 74 Light-receiving sensors 71a, 72a, 73a, 74a Collecting lenses 71b, 72b, 73b, 74b Light-receiving pinholes 78 Light-receiving focus lenses 79 Light-receiving lenses 80 Control device 81 Processing unit 82 Driving unit 83 Storage unit 84 Image generation unit 85 Input unit 91, 91a, 91b, 95, 95a, 95b Visible light blocking member 92, 92a, 92b, 96, 96a, 96b Photographing preparation light shielding member 93 Moving mechanism 94 Moving mechanism 100 Fundus photographing system 100a Projecting optical system 100b Light receiving optical system 200 Fundus photographing device 201 Optical unit section 201a Housing 201c Monitor 201e Objective lens section 203 Chin rest section 205 Base section 205i Operation section 301 Stage 302 Drive mechanism AX1, AX2, AX3 Light Axis, A1, B1... Shading position A2, B2... Non-shading position EB... Fundus EC... Fundus conjugate plane EY... Eye to be examined F1, F2, F2a, F2b... Optical filter Gr1... Front group Gr2... Rear group ML... Light emitting P1... Light emitting pinhole P2... Light receiving pinhole PS... Pupil plane RL... Reflected light U1... Common light receiving optical path U2... Light receiving optical path U3... Light receiving optical path U4... Light receiving light path

Claims (12)

A fundus photographing apparatus for projecting illumination light onto the fundus of an eye to be inspected via a scanning optical system and an objective lens, and for receiving light emitted from the fundus via the objective lens,
an infrared light source that emits infrared light as the illumination light;
an infrared light receiving element that receives reflected infrared light as the emitted light or infrared fluorescence excited by the infrared light;
a first optical filter that is detachably provided in a light receiving optical path of the infrared light and that selectively transmits the infrared fluorescence;
A photographing preparation light shielding member provided in the light receiving optical path of the infrared light and configured to be movable between a light shielding position for locally shielding harmful light and a non-light shielding position having a lower degree of light shielding than the light shielding position. When,
A fundus imaging device comprising: When an infrared fluorescence photography mode is selected, control for arranging the photography preparation light blocking member at the light blocking position in a state where the first optical filter is retracted from the light receiving optical path of the infrared light during image detection before photography. and when the infrared fluorescence imaging trigger is recognized, the first optical filter is inserted into the light receiving optical path of the infrared light, and the imaging preparation light shielding member is moved from the light shielding position to the non-light shielding position. The fundus imaging apparatus according to claim 1, further comprising a control unit that controls movement. a visible light source that emits visible light as the illumination light;
a light-receiving element for visible light that receives visible reflected light as the emitted light or visible fluorescence excited by the visible light;
provided on a common light receiving optical path common to the infrared light and the visible light, the common light receiving between a light blocking position that locally blocks harmful light and a non-light blocking position that blocks a lower degree of light blocking than the light blocking position; a visible light blocking member configured to be movable along an optical path;
The fundus imaging device according to any one of claims 1 and 2, further comprising: When the infrared fluorescence imaging mode is selected, the visible light shielding member is moved from the shielding position to the non-shielding position while the first optical filter is retracted from the light receiving optical path of the infrared light during image detection before photographing. 4. The fundus photographing apparatus according to claim 3, further comprising a control unit that moves the imaging preparation light shielding member to a position and controls the light shielding member for photographing preparation to be placed at the light shielding position. Further comprising a second optical filter that is detachably provided in the light receiving optical path of the visible light and selectively transmits the visible fluorescence,
The photographing preparation light shielding member is provided in a light receiving optical path dedicated to the infrared light,
When the visible fluorescence imaging mode is selected, the visible light shielding member is moved from the light shielding position to the non-light shielding position and the photographing preparation light shielding member is placed at the light shielding position during image detection before photographing. , further comprising a control unit that performs control to insert the second optical filter into the light receiving optical path of the visible light before or after the imaging trigger of the visible fluorescence is recognized. 3. The fundus imaging device according to . The fundus imaging apparatus according to any one of claims 1 to 5, wherein said imaging preparation light shielding member includes a first imaging preparation light shielding member which is detachably provided in a light receiving optical path dedicated to said infrared light. The fundus imaging apparatus according to any one of claims 1 to 6, wherein said imaging preparation light shielding member includes a second imaging preparation light shielding member provided movably along a light receiving optical path dedicated to said infrared light. Further comprising a second optical filter that is detachably provided in the light receiving optical path of the visible light and selectively transmits the visible fluorescence,
The photographing preparation light shielding member is provided in the common light receiving optical path,
When the visible fluorescence imaging mode is selected, the visible light shielding member is moved from the light shielding position to the non-light shielding position and the photographing preparation light shielding member is placed at the light shielding position during image detection before photographing. and performing control to move the imaging preparation light shielding member from the light shielding position to the non-light shielding position when the visible fluorescence imaging trigger is recognized, and before or after the visible fluorescence imaging trigger is recognized, the The fundus imaging apparatus according to any one of claims 3 and 4, further comprising a control unit that performs control to insert a second optical filter into the light receiving optical path of the visible light. 9. The fundus imaging apparatus according to claim 8, wherein said imaging preparation light shielding member includes a third imaging preparation light shielding member which is detachably provided in said common light receiving optical path. 3, 4, 5, wherein the moving time of the photographing preparation light blocking member from the light blocking position to the non-light blocking position is shorter than the moving time of the visible light blocking member from the light blocking position to the non-light blocking position. 9. The fundus imaging device according to any one of 8 and 9. 11. The fundus imaging apparatus according to any one of claims 3, 4, 5, 8, 9 and 10, wherein said light shielding position of said visible light shielding member is changed according to the diopter of said eye to be examined. A fundus photographing apparatus for projecting illumination light onto the fundus of an eye to be inspected via a scanning optical system and an objective lens, and for receiving light emitted from the fundus via the objective lens,
a visible light source that emits visible light as the illumination light;
a light-receiving element for visible light that receives visible reflected light as the emitted light or visible fluorescence excited by the visible light;
a second optical filter that is detachably provided in the light receiving optical path of the visible light and that selectively transmits the visible fluorescence;
provided in the light-receiving optical path of the visible light, and configured to be insertable/removable in the light-receiving optical path between a light-shielding position for locally shielding harmful light and a non-light-shielding position having a lower degree of light-shielding than the light-shielding position. a photographing preparation light shielding member;
A fundus imaging device comprising:

Images