JP2022096014A - Agrochemical granular composition and method for producing the same - Google Patents

Abstract

To provide an agrochemical granular composition with the granules less prone to flying up and consolidation even when stored for a long time.SOLUTION: An agrochemical granular composition contains an agrochemical active ingredient, a solid carrier, a surfactant and a water-soluble organic solvent. A method for producing the agrochemical granular composition includes mixing a composition containing an agrochemical active ingredient, a solid carrier and a surfactant and granulating and drying the mixture, and then impregnating the dried granules with a water-soluble organic solvent.SELECTED DRAWING: None

Description

The present invention relates to a pesticide granular composition containing a pesticide active ingredient, and more specifically, the pesticide granular composition has a hardness suitable for storage, transportation, and mechanical power spraying of a product, and powdering is suppressed, and the manufacturability is good. Pesticide granular composition. The present invention also relates to a method for producing the pesticide granular composition.

In recent years, the use of pesticide granular compositions has been increasing in agricultural settings. The pesticide granular composition has a larger apparent specific gravity than the powdered pesticide preparation, so it is not bulky, and since the scattering of fine powder is extremely small at the time of spraying, there is no concern that the operator is exposed to the pesticide, and it is easy to measure. It is a formulation type that has advantages and is easy to handle for pesticide users. On the other hand, if the hardness of granular pesticide preparations is low, pulverization occurs due to deterioration during granulation manufacturing, deterioration during product storage, vibration during transportation, etc. It causes. Since the granular pesticide preparation is sprayed as it is without diluting it with water or the like, it is often required to suppress powdering during the production of granules, the storage of the product, the transportation of the product, and the spraying by a machine.

Examples of attempts to solve the above problems include Japanese Patent Application Laid-Open No. 05-09292 (Patent Document 1) and Japanese Patent Application Laid-Open No. 2002-255703 (Patent Document 2).

Patent Document 1 relates to a pesticide granular wettable powder composition. The pesticide granular wettable powder composition is a pesticide granular composition containing one or more kinds of pesticide active ingredients and a surfactant, with an object of reducing pulverizability without lowering the disintegration property in water. , Ethylene glycol, propylene glycol, or polyethylene glycol or polypropylene glycol having a molecular weight of 1000 or less is disclosed.

Patent Document 2 relates to a pesticide granular composition. Mixing of pesticide active ingredient, dextrin, and water or water-water-soluble organic solvent with the task of improving hydration and dispersibility with less powdering without solidification even after long-term storage. A pesticide granular composition containing a solvent and coated with diatomaceous earth, and a method for producing the same are disclosed.

Japanese Unexamined Patent Publication No. 05-09292 Japanese Unexamined Patent Publication No. 2002-255703

The Pesticide Manual 8th Edition (British Crop Production Council, 2018)

If the hardness of the pesticide granular composition is low, pulverization will occur due to deterioration during granulation manufacturing, product storage, vibration during transportation, etc., and the generated fine powder will cause drift during spraying and exposure of pesticides to workers. Will be. In response to these problems, Patent Document 1 attempts to suppress the powdering of the granular preparation by preliminarily adding a water-soluble organic solvent such as ethylene glycol during the granulation and production of the hydrating pesticide granular composition. ing. However, by adding a water-soluble organic solvent such as ethylene glycol during the granulation production, it is difficult to adjust the amount of water added during the granulation, and there are problems in the manufacturability of the granule and the drying efficiency after the granulation.

In the prior document 2, a pesticide is prepared by adding a mixed solution of dextrin and water and a water-soluble organic solvent in advance at the time of granulation and production of a pesticide granular composition, granulating the granule, and then covering the surface of the granule with diatomaceous earth. We are trying to suppress the powdering of the granular composition. However, although the granulation property is excellent, the dispersibility is improved, so that the powdering of the granules cannot be completely suppressed. Therefore, it has been desired to develop a technique for producing a pesticide granular composition that is easy to dry in the heat-drying step, is safe and inexpensive, and suppresses powdering. An object of the present invention is to provide a pesticide granular composition having excellent manufacturability in which powdering is suppressed during granulation production, product storage, product transportation, and mechanical power spraying, and a method for producing the same. It is in.

As a result of various studies to solve the above problems, the present inventors have found that pesticide active ingredients, solid carriers, and the like.
When producing a pesticide granular composition containing a surfactant and a water-soluble organic solvent, the composition containing the pesticide active ingredient, a solid carrier and a surfactant is first kneaded, granulated and dried to form a granule base. By producing granules and then impregnating the granule base with a water-soluble organic solvent, powdering during granulation production, product storage, product transportation, and mechanical spraying was suppressed. The present invention has been completed by finding that a pesticide granular composition having good manufacturability can be obtained.

That is, the present invention
[1] A pesticide granular composition containing a pesticide active ingredient, a solid carrier, a surfactant, a water-soluble organic solvent,
[2] One or two selected from the group consisting of binders, tackifiers, colorants, anti-caking agents, disintegrants, antioxidants, defoamers, pH regulators and light stabilizers. The pesticide granular composition according to [1], which further comprises the above agents.
[3] The pesticide granular composition according to [1] or [2], wherein the pesticide active ingredient is one or more selected from ipfencarbazone, imazosulfone, penokislam, benzobicyclon, oxadichromephone and pyracronyl. object,
[4] The pesticide granular composition according to any one of [1] and [3], wherein the pesticide active ingredient is one or more selected from penoxyslam and benzobicyclon.
[5] The pesticide granular composition according to any one of [1] and [3], wherein the pesticide active ingredient is one or more selected from oxadichromephon and pyracronyl.
[6] The pesticide granular composition according to any one of [1] and [3], wherein the pesticide active ingredient is one or more selected from ipfencarbazone, imazosulfuron and benzobicyclon. ,
[7] The pesticide granular composition according to any one of [1] and [6], wherein the solid carrier is one or more selected from calcium carbonate, hydrous silicic acid, calcined diatomaceous earth and clay.
[8] Surfactants are alkyl sulfates, formalin condensates of alkylnaphthalene sulfonates, polyoxyethylene alkyl ether phosphate potassium salts, polyoxyethylene allylphenyl ether phosphate amine salts, dialkyl sulfosuccinates, polycarboxylate metals. The pesticide granular composition according to any one of [1] and [7], which is one or more selected from a salt and sodium alphaolein sulfonate.
[9] The pesticide granular composition according to any one of [1] and [8], wherein the water-soluble organic solvent is ethylene glycol, propylene glycol, polyethylene glycol, or polypropylene glycol.
[10] The composition comprising a pesticide active ingredient, a solid carrier and a surfactant is kneaded, granulated and dried, and then the granulated product is impregnated with a water-soluble organic solvent. [1] ] And [9] The method for producing a pesticide granular composition according to any one of the above,
[11] The method for producing a pesticide granular composition according to [10], wherein the content of the water-soluble organic solvent is 0.5 to 10% by mass of the total amount of the pesticide granular composition.
Regarding.

The present invention provides a pesticide granular composition having good manufacturability, in which powdering is suppressed during granulation production, product storage, product transportation, and mechanical power spraying.

The pesticide granulation of the pesticide granular composition of the present invention is, for example, a stirring granulation method, a rolling granulation method and a fluidized layer granulation method among the granulation methods used for producing a normal pesticide granulation. It can be manufactured by a granulation method using a stirring and mixing machine or a granulation method using an extrusion granulation machine such as an extrusion granulation method (for example, Patent Office Standard Technology Collection-Agricultural Pharmaceutical Formulation Technology-Database "Mixing / Kneading". "Technology", "Granulation technology", "Granulation / molding technology"; Internet <URL: https://warp.da.ndl.go.jp/info:ndljp/pid/10342974/www.jpo.go.jp/ See shiryou / s_sonota / hyoujun_gijutsu / nouyaku / tt1302-061_nouyaku.htm>).

In the present invention, the "hardness" of the "pesticide granular composition" indicates, for example, the strength of the granules against impact, friction, etc. It is an important factor that determines the underwater disintegration property.

In the present invention, "mechanical power spraying" means, for example, a punkle sprayer, a manned helicopter, a radiocon helicopter, a radiocon boat, a drone, a one-shot sprayer, a power spreader, a carry type (manual or automatic) manual or automatic power sprayer. , A backpack type (manual or automatic) power sprayer, a helicopter granule sprayer, a manual sprayer, etc.

In the granulation and production of the pesticide granular composition of the present invention, usually, 0.5 to 30% by mass of water can be used for granulation in the composition mixture for pesticide granules. Specifically, first, a pesticide active ingredient, a surfactant, a solid substance, and other necessary ingredients are added and uniformly mixed in a stirring mixer to produce a granulated material as a granule base. ,dry. At this time, when the solid component is like a lump, it is preferable to pulverize it into an appropriate powder in advance to facilitate the mixing operation. The particle size of the appropriate powder is about 0.5 to 1000 μm. Next, an appropriate amount of a water-soluble organic solvent or a water-water-soluble organic solvent mixed solvent is added to the granulated granule base in the range of 0.5 to 15% by mass, impregnated, and further mixed in a stirring mixer. Stir and mix until smooth rolling. When the mixture becomes smooth, it is taken out and sieved to the required particle size classification to make pesticide granules. In the present invention, "% by mass" means weight percent (w / w%) with respect to the total composition.

The pesticide active ingredients of the granular pesticide composition of the present invention, ipfencarbazone, imazosulfone, penoxthram, benzobicyclon, oxadichromephone, and pyracronyl are known compounds sold as pesticide herbicides (eg, non-patent literature). See 1). In addition, polyoxyethylene alkyl ether phosphate potassium salt, polycarboxylic acid metal salt, sodium alphaolein sulfonate, glycols, polyethylene glycol, polypropylene glycol, calcium carbonate, hydrous silicate, which are auxiliary materials used in the present invention, Calcined diatomaceous earth and clay are known products and are commonly used in Japan and overseas as auxiliary materials for pesticide formulation (for example, "solid carrier" in the Patent Office Standard Technology Collection (Agricultural Chemicals Technology) database. Internet <URL: https://warp.da.ndl.go.jp/info:ndljp/pid/10342974/www.jpo.go.jp/shiryou/s_sonota/hyoujun_gijutsu/nouyaku/tt1302-061_nouyaku.htm> reference).

In the present invention, agricultural and horticultural fungicides, agricultural and horticultural insecticides, and agricultural and horticultural herbicides can be used as pesticide active ingredients. Examples of agricultural and horticultural fungicides include aureofungin, azaconazole, azithiram, acypetacs, acibenzolar, acibenzolar-S-methyl, and azoxy. Azoxystrobin, anilazine, amisulbrom, compound 1 (pyrapropoyne), ampropylfos, ametoctradin, allyl alcohol, aldimorph, ambam , Isotianil, isovaledione, isopyrazam, isofetamid, isoflucypram, isoprothiolane, ipconazole, ipfentrifluconazole, ipfentrifluconazole (ipflufenoquin), iprodione, iprovalicarb, iprobenfos, imazalil, iminoctadine, metam, iminoctadine albesilate (iminoctadine-albesilate), iminoctadine-albesilate -triacetate, imibenconazole, impyrfluxam, uniconazole, uniconazole-P, echlomezole, edifenphos, etaconazole, etaconazole, etaconazole. ethaboxam), ethirimol, etem, ethoxyquin, etridiazole, enestroburin, enoxastrobin (enoxastrobin), epoxiconazole, oxadixyl, oxathiapiprolin, oxycarboxin, copper-8-quinolinolate, oxytetracycline, oxytetracycline (copper-oxinate), oxpoconazole, oxpoconazole-fumarate, oxolinic acid, octhilinone, ofurace, orysastrobin, carbam (carbam, metam-sodium), kasugamycin, carbamorph, carpropamid, carbendazim, carboxin, carvone, quinazamid, quinacetol, Kinoxyfen, quinofumelin, quinomethionat, quinomethionate, captafol, captan, kiralaxyl, quinconazole, quintozene, guazatine, guazatine Cufraneb, cuprobam, coumoxystrobin, glyodin, griseofulvin, climbazole, cresol, kresoxim-methyl, clotrimate (chlozolinate) ), Clotrimazole, chlobenthiazone, chloraniformethan, chloranil, chlorquinox, ku Chlorothalonil, chlorfenazole, chlorodinitronaphthalene, chlorothalonil, chloroneb, salicylanilide, zarilamid, cyazofamid, diethylpyropamid (Diethyl pyrocarbonate), diethofencarb, cyclafuramid, diclocymet, dichlozoline, dichlobutrazol, dichlofluanid, cycloheximide, cycloheximide dichlobentiazox, dichlomezine, dichloran, dichlorophen, dichlone, disulfiram, ditalimfos, dithianon, diniconazole-din M), zineb, dinocap, dinocton, dinosulfon, dinoterbon, dinobuton, dinopenton, dipymetitrone, dipyrithione diphenylamine, diphenoconazole, cyflufenamid, diflumetorim, cyproconazole, cyprodinil, cyprofuram, cypendazole, cypendazole, simeconazole Dimethomorph, Simoxani Cymoxanil, dimoxystrobin, ziram, silthiofam, streptomycin, streptomycin, sultropen, sedaxane, zoxamide, dazomet (zoxamide) dazomet, thiadiazin, tiadinil, thiadifluor, thiabendazole, tioxymid, thiochlorfenphim, thiophanate, thiophanate-methyl, Thiofluzamide, thicyofen, thioquinox, thiram, decafentin, tecnazene, tecloftalam, tecoram, tetraconazole, tetraconazole debacarb, dehydroacetic acid, tebuconazole, tebufloquin, dodicin, dodine, dodecylbenzenesulfonate bisethylenediamine copper complex salt (II) (DBEDC), dodemorph, Drazoxolon, triadimenol, triadimefon, triazbutil, triazoxide, triamiphos, triarimol, trichlamide, triclopyricarb , Tricyclazole, triticonazole, tridemorph, tributyltin oxide, triflumizole, Trifloxystrobin, triforine, tolylfluanid, tolclofos-methyl, tolprocarb, natamycin, nabam, nitrostyrene, nitro Tasal-isopropyl, nuarimol, copper nonylphenol sulfonate, halacrinate, validamycin, valifenalate, harpin protein, picalbut Razox (picarbutrazox), bixafen (bixafen), picoxystrobin, picobenzamide, pydiflumetofen, bithionol, bitertanol, hydroxyisoxazole, Hydroisoxazole-potassium, binapacryl, biphenyl, piperalin, hymexazol, pyraoxystrobin, pyracarbolid, pyraclostrobin. ), Compound 1 (pyrapropoyne), pyraziflumid, pyrazophos, pyrametostrobin, pyriofenone, pyridinitrile, pyridiflumetofen, pyrisoxazole, pyrisoxazole Methyl (pyridachlometyl), pyrifenox, pyribencarb, pyriminostrobin ), Pyrimethanil, pyroxychlor, pyroxyfur, pyroquilon, vinclozolin, ferbam, famoxadone, fenapanil, fenaminodone ), Fenaminstrobin, fenarimol, fenitropan, fenoxanil, ferimzone, ferbam, fentin, fenpiclonil, fenpiclonil (fenpiclonil) fenpicoxamid, fenpyrazamine, fenbuconazole, fenfuram, fenpropidin, fenpropimorph, fenhexamid, phthalide, buthiobate , Butylamine, bupirimate, fuberidazole, blasticidin-S, furametpyr, furalaxyl, fluacrypyrim, fluazinam, fluindap ), Fluoxastrobin, fluoxapiprolin, fluotrimazole, fluopicolide, fluopimomide, fluopyram, fluoroimide, furcarbanil. , Fluxapyroxad, fluquinconazole, furconazole, furconazol e-cis, fludioxonil, flusilazole, flusulfamide, flutianil, flutolanil, flutriafol, flufenoxystrobin, furfural, Flubeneteram, furmecyclox, flumetover, flumorph, proquinazid, prochloraz, procymidone, prothiocarb, prothioconazole, Pronitridine, propamocarb, propiconazole, propineb, furophanate, probenazole, bromuconazole, florylpicoxamid, hexachlorobutadiene. (Hexachlorobutadiene), hexaconazole, hexylthiofos, bethoxazin, benaraxyl, benaraxyl-M, benodanil, benomyl, benomyl, pefrazoate Benquinox, penconazole, benzamorf, pencicuron, benzohydroxamic acid, benzovindiflupyr, bentaluron, benthiazole, bencha Bali Calve (
benthiavalicarb), Benthiavalicarb-isopropyl, penthiopyrad, penflufen, boscalid, phosdiphen, fosetyl, fosetyl-Al, polyoxin (Polyoxins), polyoxorim, polycarbamate, folpet, formaldehyde, machine oil, maneb, mancozeb, mandipropamid, mandest Robin (mandestrobin), microzoline (myclozolin), microbutanil (myclobutanil), mildiomycin (mildiomycin), milneb (milneb), mecarbinzid (mecarbinzid), metasulfocarb (methasulfocarb), metazoxolon (metam), meta Metam-sodium, metalaxyl, metalaxyl-M, metiram, methyl isothiocyanate, mepthyldinocap, metyltetraprole , Metconazole, metsulfovax, methfuroxam, metminostrobin, metrafenone, mepanipyrim, mefenoxam, mefentrifluconazole, mefentrifluconazole. Meptyldinocap, mepronil, mebenil, iodomethane, rabenzazole, methyl bromide, benzalco chloride Inorganic bactericides such as benzalkonium chloride, basic copper chloride, basic copper sulfate, silver metallic silver, sodium hypochlorote, and hydroxylated sulphate. Cupric hydroxide, wettable sulfur, calcium polysulfide, potassium hydrogen carbonate, sodium hydrogen carbonate, inorganic sulfur, anhydrous Copper-based compounds such as copper sulfate anhydride, nickel dimethyldithiocarbamate, 8-hydroxyquinoline copper, zinc sulfate, copper sulfate pentahydrate. ) Etc. can be exemplified.

For example, 3,5-xylyl methylcarbamate (XMC), Bacillus thuringiensis aizawai, Bacillus thuringiensis israelensis, Bacillus thuringiensis japonensis, Bacillus thuringiensis kurstaki, Bacillus thuringiensis , Bacillus thuringiensis-produced crystalline protein toxin, BPMC, Bt toxin insecticidal compound, CPCBS (chlorfenson), DCIP (dichlorodiisopropyl ether), DD (1, 3-Dichloropropene), DDT, NAC, O-4-dimethylsulfamoylphenyl O, O-diethyl phosphorothioate (DSP), O-ethyl O-4-nitrophenyl phenylphosphonothioate (EPN), tripropylisocyanurate (TPIC), acrinathrin, acynonapyr, azadirachtin, azinphos-methyl ), Acequinocyl, acetamiprid, acetoprole, acephate, abamectin, afidopyropen, avelmectin-B, amidoflumet, amitras , Alanycarb, aldicarb, aldoxycarb, aldrin, alpha-endosulfan, alpha-cypermethrin, albendazole, alleslin allethrin), isazofos, isamidofos, isoamidephos (iso) amidofos, isoxathion, isocycloseram, isofenphos, isoprocarb (MIPC), epsilon-metofluthrin, epsilon-monfluthrin (epsilon-momfluorothrin), emamectin Imiciafos, imidac1oprid, imiprotrin, indoxacarb, esfenvalerate, ethiofencarb, etion, ethiprole, ethiprole, ethiprole, ethiprole Ethofenprox, ethoprophos, etrimfos, emamectin, emamectin-benzoate, endosulfan, empentthrin, oxazosulfyl, oxazosulfyl. oxamyl, oxydemeton-methyl, oxydeprofos (ESP), oxibendazole, oxfendazole, potassium oleate, sodium oleate ), Cadusafos, kappa-bifenthrin, cartap, carbary1, carbosulfan, carbofuryl, gamma-cyhalothrin, xylylcarb. ), Quinalphos, kinoprene, chinomethionat, cloethocarb, clothianidin, croff Clofentezine, chromafenozide, chlorantraniliprole, chlorethoxyfos, chlordimeform, chlordane, chlorpyrifos, chlorpyrifos-methyl chlorpy Chlorphenapyr, chlorfenson, ch1orfenvinphos, chlorfluazuron, chlorobenzilate, chlorobenzoate, chloroprallethrin, kersen ( Dicofol, salithion, cyhalodiamide, cyanophos: CYAP, diafenthiuron, diamidafos, cyantraniliprole, theta-cypermethrin. cypermethrin, cyetpyrafen, dienochlor, cyenopyrafen, dioxabenzofos, diofenolan, sigma-cypermethrin, cyclaniliprole dichlofenthion: ECP, cyclobutrifluram, cycloprothrin, dichlorvos (DDVP), dicloromezotiaz, disulfoton, dinotefuran, cyhalodiamide, Cyhalothrin, cyphenothrin, cyfluthrin, Diflubenzuron, cyflumetofen, cyproflanilide, diflovidazin, cyhexatin, dimpropyridaz, cypermethrin, cypermethrin, dimethylbinphos dimefluthrin, silafluofen, cyromazine, spinetoram, spinosad, spirodiclofen, spiropidion, spirotetramat, spiromesifen (sulfluramid), sulprofos, sulfoxaflor, zeta-cypermethrin, diazinon, tau-fluvalinate, dazomet, thiacloprid, Thiamethoxam, tioxazafen, thiodicarb, thiocyclam, thiosultap, thiosultap-sodium, thionazin, thiometon, thiometon ), Deet, dieldrin, tetrachlorantraniliprole, tetrach1orvinphos, tetradifon, tetraniliprole, tetramethylfluthrin, Tetramethrin, tebupirimfos, tebufenozide ozide, tebufenpyrad, tefluthrin, teflubenzuron, demeton-S-methyl, temephos, deltamethrin, terbufos, doramectin , Tralopyril, tralomethrin, transfluthrin, triazamate, triazuron, trichlamide, trichlorphon (DEP), triflumezopyrim, triflumezopyrim, triflumezopyrim ), Tolfenpyrad, naled: BRP, nicofluprole, nithiazine, nitenpyram, novaluron, noviflumuron, hydroprene, vanilip ), Vamidothion, parathion, parathion-methyl, halfenprox, halofenozide, bistrifluron, bisultap, hydramethylnon ), Hydroxy propyl starch, binapacryl, pyflubumide, bifenazate, bifenthrin, pymetrozine, pyraclorfos, pyrafluprole, pyridafen pyridafenthion), pyridaben, pyridalyl, pyrifluquinazon, pyriprol (p) yriprole, pyriproxyfen, pyrimicarb, pyrimidifen, pyriminostrobin, pyrimiphos-methy1, pyrethrins, fiproni1 and fenazaquin. Fenamiphos, bromopropylate, fenitrothion (MEP), fenoxycarb, fenothiocarb, phenothrin, fenobucarb, fensulfothion, fenthion fenthion: MPP, phenthoate (PAP), fenvalerate, fenpyroximate, fenpropathrin, fenbendazole, fosthiazate, formetanate, butatiophos (butathiofos), buprofezin, furathiocarb, prallethrin, fluacrypyrim, fluazaindolizine, flupyrimin, fluazinam, fluazuron, fluazuron fluensulfone), fluxametamide, flucycloxuron, flucythrinate, fluvalinate, flufiprole, flupyradifurone, flupyrazofos, flupyrazofos, flupyrazofos , Flufenoxystrobin, flufenoxron uron, flufenzine, flufenoprox, fluproxyfen, flubrocythrinate, fluhexafon, flubendiamide, flupentiofenox, Flumethrin, flurimfen, prothiofos, protrifenbute, flonicamid, propaphos, propargite (BPPS), profenofos, broflanilide , Profluthrin, propoxur (PHC), fromometoquin, alpha-bromadiolone, bromopropylate, beta-cyfluthrin, hexaflumuron ), Hexythiazox, heptafluthrin, heptenophos, permethrin, benclothiaz, bendiocarb, benzpyrimoxan, benzpyrimoxan, bensu1tap (benzoximate), benfuracarb, phoxim, phosalone, fosthietan, phosphamidon, phosphocarb, phosmet (PMP), polynactins, holmotion formothion, phorate, machine oil, malathion, milbemycin, milbemycin-A, milbemectin bemectin, mecarbam, mesulfenfos, methomyl, metaldehyde, metaflumizone, metamidophos, metam-ammonium, metam-sodium ), Methiocarb, methidathion (DMTP), methylisothiocyanate, methylneodecanamide, methylparathion, metoxadiazone, methoxychlor, methoxyfenozide. Metofluthrin, metoprene, metolcarb, meperfluthrin, mevinphos, monocrotophos, monosultap, momfluorothrin, lambda-cyhalothrin ), Ryanodine, lufenuron, rescalure, resmethrin, lepimectin, rotenone, levamisol hydrochloride, fenbutatin oxide, morantel tartrate. tartarate, methyl bromide, cyhexatin hydroxide, calcium cyanamide, calcium polysulfide, sulfur, and nicotine-sulfate, etc. Can be exemplified.

As agricultural and horticultural herbicides used for the same purpose, for example, 1-naphthylacetamide, 2,4-PA, 2,3,6-TBA, 2,4,5-T, 2,4,5-TB, 2 , 4-D, 2,4-DB, 2,4-DEB, 2,4-DEP, 3,4-DA, 3,4-DB, 3,4-DP, 4-CPA, 4-CPB, 4 -CPP, MCP, MCPA, MCPA thioethyl, MCPB, ioxynil, aclonifen, azafenidin, acifluorfen, aziprotryne, azimsulfuron, ashlam , Acetochlor, atrazine, atraton, anisuron, anilofos, aviglycine, abscisic acid, amiclabazone, amidosulfuron , Amitrole, aminocyclopyrachlor, aminopyralid, amibuzin, amiprophos-methyl, ametridione, ametridine, alachlor, Allidochlor, alloxydim, alorac, iofensulfuron, isouron, isocarbamid, isoxachlortole, isoxapyrifop, iso Xaflutole, isoxaben, isoxaben, isocil, isonorruron, isoproturon, isopropalin, isopolinate, isomethiozin, inabenfide, inabenfide. ipazine), i Ipfencarbazone, iprymidam, imazaquin, imazapic, imazapyr, imazamethapyr, imazamethabenz, imazamethabenz, imazamethabenz-methyl ), Imazethapyr, imazosulfuron, indaziflam, indanofan, indolebutyric acid, uniconazole-P, eglinazine, esprocarb Ethametsulfuron, ethametsulfuron-methyl, ethalfluralin, ethiolate, ethychlozate-ethyl, ethidimuron, etinofen, etinofen ), ethoxysulfuron, ethoxyfen, etnipromid, ethofumesate, etobenzanid, epyrifenacil, epronaz, erbon, endtal , Oxadiazon, oxadiargyl, oxaziclomefone, oxasulfuron, oxapyrazon, oxyfluorfen, oryzalin, orthosulfamuron, orthosulfamuron ), Cafenstrole, cambendichlor, carbasulam, calf Entrazone, carfentrazone-ethyl, carbutilate, carbetamide, carboxazole, quizalofop, quizalofop-P, quizalofop- Ethyl (quizalofop-ethyl), xylachlor, quinoclamine, quinonamid, quinclorac, quinmerac, cumyluron, clacyfos, cliodinate, Glyphosate, glufosinate, glufosinate-P, credazine, clethodim, cloxyfonac, clodinafop, clodinafop-propargyl Chlotoluron, clopyralid, cloproxydim, cloprop, chlorbromuron, clofop, clomazone, clomethoxyni1, chlomethoxyfen, Clomeprop, chlorazifop, chlorazine, chloranocryl, chloramben, cloransulam, cloransulam-methyl, chloridazon, chlorimuron, chlorimuron -Ethyl (chlorimuron-ethyl), chlorsulfuron, chlorthal, chlorthiamid, chlorturlon (chlor) toluron, chlornitrofen, chlorfenac, chlorfenprop, chlorbufam, chlorphthalim, chlorflurazole, chlorflurenol, chlorflurenol (chlorflurenol) chlorprocarb, chlorpropham, chlormequat, chloreturon, chloroxynil, chloroxuron, chlorotoluron, chloropon, saflufenacil, cyanazine Cyanatryn, diallate, diuron, diethamquat, dicamba, cycluron, cycloate, cycloxydim, diclosulam, cyclosulfamron (diclosulam) cyclosulfamuron, cyclopyranil, cyclopyrimorate, dichlorprop, dichlorprop-P, dichlorprop-P, dichlobenil, dichlobenz-methyl, dicroofop , Dichlorofop-methyl, dichlormate, dichloralurea, diquat, cisanilide, disul, siduron, dithiopyr, dinitramine , Cinidon-ethyl, dinosam, cinosulfuron, dinoseb, dinoterb, dinophenat e), dinoprop, cyhalofop-butyl, diphenamid, difenoxuron, difenopenten, difenzoquat, cybutryne, cyprazine, Cyprazole, diflufenican, diflufenzopyr, dipropetryn, cypromid, cyperquat, gibberellin, simazine, dimexano dimesulfazet, dimethachlor, dimidazon, dimethametryn, dimethenamid, simetryn, simeton, dimepiperate, dimepiperate, dimefuron, dimefuron swep, sulglycapin, sulcotrione, sulfallate, sulfentrazone, sulfosulfuron, sulfometuron, sulfometuron-methyl (Secbumeton), sethoxydim, sebuthylazine, terbacil, daimuron, dazomet, dalapon, thiazafluron, thiazopyr, tiafenacil (Thiencarbazone), thiencarbazone-methyl, thiocarbazil, thioclorim, thibencarb (thi) obencarb, thidiazimin, thidiazuron, thifensulfuron, thifensulfuron-methyl, desmedipham, desmetryn, tetflupyrolimet , Tetrafluron, thenylchlor, tebutam, tebuthiuron, terbumeton, tepraloxydim, tefuryltrione, tembotrione, delacrol Terbacil, terbucarb, terbuchlor, terbuthylazine, terbutryn, topramezone, tralkoxydim, triaziflam, triasulfuron ), Triallate, trietazine, tricamba, triclopyr, tridiphane, tritac, tritosulfuron, trifludimoxazin, triflus Triflusulfuron, triflusulfuron-methyl, trifluralin, trifloxysulfuron, tripropindan, tribenuron, tribenuron-methyl, Trifop, trifopsime, trimeturon, tolpyralate, naptalam, naproanili Do (naproanilide), napropamide, nicosulfuron, nitralin, nitrofen, nitrofluorfen, nipyraclofen, neburon, norflurazon, norlon (norflurazon) noruron, barban, paclobutrazol, paraquat, parafluron, haloxydine, halauxifen, haloxyfop, haloxyfop-P, Haloxyfop-methyl, halosafen, halosulfuron, halosulfuron-methyl, bilanafos, bixlozone, picloram, picolinafen, picolinafen, Bicyclopyrone, bispyribac, bispyribac-sodium, pydanon, pinoxaden, bifenox, piperophos, hymexazol, pyraclonil Pyrasulfotole, pyrazoxifen, pyrazosulfuron, pyrazosulfuron-ethyl, pyrazolate, biranafos, pyraflufen, pyraflufen-ethyl Pyriclor, pyridafol, pyrithiobac, pyrithiobac-sodium, pyridate, pyrif Pyriftalid, pyribticarb, pyribenzoxim, pyrimisulfan, primisulfuron, pyriminobac-methyl, pyroxasulfone, pyroxsulam , Fenasulam, phenisopham, fenuron, fenoxasulfone, fenoxaprop, fenoxaprop-P, fenoxaprop-ethyl. ), Phenothio1, fenoprop, phenobenzuron, fenquinotrione, fenthiaprop, fenteracol, fentrazamide, fenmedifam (), phenothio1 phenmedipham), phenmedipham-ethyl, butachlor, butafenacil, butamifos, buthiuron, buthidazole, butylate, buturon, butenachlor (Butenachlor), butroxydim, butralin, butroxydim, flazasulfuron, flamprop, furyloxyfen, prynachlor, primisulfuronmethyl (butenachlor), butroxydim, butralin, butroxydim, flazasulfuron. primisulfuron-methyl, fluazifop, fluazifop-P, fluazifop-butyl, fluazolate, fluroxypyr, fluothiur on), fluometuron, fluoroglycofen, flurochloridone, fluorodifen, fluoronitrofen, fluoromidine, flucarbazone, flucarbazone-sodium (on) flucarbazone-sodium, fluchloralin, flucetosulfuron, fluthiacet, fluthiacet-methyl, flupyrsulfuron, flufenacet, flufenican ), Flufenpyr, flupropacil, flupropanate, flupoxam, flumioxazin, flumiclorac, flumiclorac-pentyl, flumiclorac-pentyl flumipropyn, flumezin, fluometuron, flumetsulam, fluridone, flurtamone, fluroxypyr, pretilachlor, proxan, proxan, proxan procyazine, prodiamine, prosulfalin, prosulfuron, prosulfocarb, propaquizafop, propachlor, propazine, propanil ), Propyzamide, propisochlor, prohydrojasmon, propyrisulfuro n), propham, profluazol, profluuralin, prohexadione-calcium, propoxycarbazone, propoxycarbazone-sodium, propoxycarbazone-sodium (Prooxydim), bromacil, brompyrazon, prometryn, prometon, bromoxynil, bromofenoxim, bromobutide, bromobonil, florasulam , Florpyrauxifen, hexachloroacetone, hexazinone, petthoxamid, benazolin, penoxsulam, pebulate, beflubutamid, beflubutamid-M -M, vernolate, perfluidone, bencarbazone, benzadox, benzipram, benzylaminopurine, benzthiazuron, benzfendizone , Bensulide, bensulfuron-methyl, benzoylprop, benzobicyclon, benzofenap, benzofluor, bentazone, pentanochlor (Pentanochlor), Benthiocarb, pendimethalin, pentoxazone, benfluralin, Benf Benfuresate, fosamine, fomesafen, foramsulfuron, forchlorfenuron, maleic hydrazide, mecoprop, mecoprop-P (mecoprop-P) P), medinoterb, mesosulfuron, mesosulfuron-methyl, mesotrione, mesoprazine, mesoprotryne, metazachlor, methazole, metazosulfuron. metazosulfuron, metabenzthiazuron, metamitron, metamifop, metam, methalpropalin, methiuron, methiozolin, methiobencarb, Methyldymron, metoxuron, metosulon, metsulfuron, metsulfuron-methyl (metsu1furon-methy1), metflurazon, metflurazon, metobromlon (metobromuron), metobromlon (metobromuron) Methyl chlor, metribuzin, mepiquat-chloride, mefenacet, mefluidide, monalide, monisouron, monuron, monochloroacetic acid acid), monolinuron, molinate, morfamquat, iodosulfuron, yo Dosulfuron-methyl-sodium, iodobonil, iodomethane, lactofen, lancotrione, linuron, rimsulfuron, lenacil, Examples thereof include rhodethanil, calcium peroxide, and methyl bromide. Ipfencarbazone, imazosulfuron, penokislam, benzobicyclon, oxadichromephone, pyracronyl are preferred, and in particular, penokislam and benzobicyclon, oxadichromephon and pyracronyl, or a combination of ipfencarbazone and imazosulfone and benzobicyclon are preferred. ..

In addition, as a drug damage reducing agent (also referred to as safener), for example, 1,8-naphthalic anhydride, isoxadifen-ethyl, furilazole, cyprosulfamide ( cyprosulfamide, cyometrinil, dichlormid, dimepiperate, thiencarbazone-methyl, fenchlorazole-ethyl, fenclorim, fluxofenim, fluxofenim It is also possible to use (flurazole), benoxacor, metcamifen, mefenpyr-diethyl and the like in combination.

In addition to the above-mentioned pesticide active ingredients, further biopesticides can be used or used. Specific examples thereof include, for example, Agrobacterium radiobacter strain K84 (for example, "Galltrol &#8722; A (registered trademark)" manufactured by "AgBioChem, CA"), Agrobacterium radiobacter. ) Strain K1026 (for example, "Nogall (registered trademark)" manufactured by "Becker Underwood, US"), Agrobacterium radiobacter strain 84 (for example, "Bacte" manufactured by "Nippon Agricultural Chemicals Co., Ltd.") Agrobacterium spp. Such as "Rose (registered trademark)"; Ampelomyces quisqualis strain AQ10 (for example, "AQ 10 (registered trademark)" manufactured by "Intrachem Bio Italia & Co. KG"), etc. Ampelomyces sp.; Aspergillus flavus (eg, "Afla-Guard®" from "Syngenta"), Aspergillus flavus strain AF36 (eg, "Arizona Cotton") A mixture of sprouting spores of Aureobasidium pullulans strain DSM14940 and sprouting spores of strain DSM14941; (For example, "Botector®" from "bio-ferm, GmbH"), etc. Aureobasidium spp.; Bacillus amyloliquefaciens strain AT-332 (eg, for example. "Impression Clear (registered trademark)" manufactured by "Idemitsu Agri Co., Ltd."), B246 (for example, "Avogreen (registered trademark)" manufactured by "UnIVersity of Pretoria"), Bacillus amyloliquefaciens. Bacillus amilolikue Bacillus amyloliquefaciens strain D747 (eg, "Bacstar®" from "Etec Crop Solutions, NZ"), Bacillus amyloliquefaciens strain DB101 (eg, "Dagutat Bio lab, ZA") "Shelter®"), Bacillus amyloliquefaciens strain DB102 (eg "Artemis®" from "Dagutat Bio lab, ZA"), Bacillus amyloliquefaciens (Bacillus amyloliquefaciens) FZB42 (eg, "RhizoVital®" from "ABiTEP, DE"), Bacillus amyloliquefaciens strain GB03 (eg, "Bayer Crop Science AG, DE") "Kodiak®"), Bacillus amyloliquefaciens strain MBI600 (eg "Subtilex®" from "Becker Underwood, US"), Bacillus cepacia (eg) , "Deny Stine®" from "Microbial Products"), Bacillus cereus strain BP01 (eg "Mepichlor®" from "Arysta, US"), Bacillus firmus) strain I-1582 (eg, "BioNeem®" from "AgoGreen"), Bacillus laterosporus (eg, "Bio-Tode®" from "Agro-Organics, SA") ”), Bacillus licheniformis strain SB3086 (eg,“ EcoGuard Biofungicide® ”manufactured by“ Novozymes ”), Bacillus maroccanus (eg,“ Micro Flo Company ”). , Bacillus megaterium strain YFM3.25 (eg, "Bioarc®" from "BioArc"), Bacillus metiens ("Micro Flo Company"), Bacillus. Bacillus mycoides isolate J. (eg, "BmJ®" from "Certis USA"), Bacillus popilliae (eg, "Cronox" from "Bio-Crop, CO" (registered) Trademark) "), Bacillus pumilus strain BU F-33 (eg," Integral F-33® "manufactured by" Becker Underwood, US "), Bacillus pumilus strain GB34 (eg) For example, "Yield Shield®" from "Bayer CropScience AG, DE"), QST2808 from Bacillus pumilus (eg, "Sonata®" from "Bayer CropScience LP, US"). , Bacillus simplex strain CGF2856 ("Momihope wettable powder (registered trademark)" manufactured by "Arista Life Sciences Co., Ltd."), Bacillus sphaericus, in particular, antigen-type H5a5b strain 2362 (eg, for example. , "VectoLex®" manufactured by "Valent BioSciences, US"), Bacillus subtilis (eg "Botkiller wettable powder (registered trademark)" manufactured by "Idemitsu Agri Co., Ltd."), Bacillus subtilis. Bacillus subtilis var. Amyloliquefaciens strain FZB24 (eg, "Taegro®" from "Novozyme Biologicals, Inc. US"), Bacillus subtilis strain QST713 / AQ713 ( For example, "SERENADE MAX (registered trademark)" made by "Bayer Crop Science LP, US"), Bacillus subtilis. Stock AQ30002 (for example, "Serenade-DPZ®"), Bacillus subtilis strain D747 (for example, "Ecoshot (registered trademark)" manufactured by "Kumiai Chemical Co., Ltd."), Bacillus subtilis (Bacillus subtilis) strain HAI-0404 (for example, "Agrocare wettable powder (registered trademark)" manufactured by "Nisso Green Co., Ltd."), Bacillus subtilis strain MBI600 (for example, "Idemitsu Kosan Co., Ltd." Bacillus subtilis strain Y1336 (for example, "Bacillus wettable powder (registered trademark)" manufactured by "Arista Life Science Co., Ltd."), Bacillus subtilis Bacillus thuringiensis strain AM65-52 (eg, "VectoBac®" from "Valent BioSciences, US"), Bacillus thuringiensis israelensis strain BMP144 (eg, " Bacillus thuringiensis subspec. Kurstaki strain BMP 123 (Becker Microbial Products, IL), Bacillus thuringiensis (registered trademark), Bacillus thuringiensis subspec. Bacillus thuringiensis Kurstaki strain HD-1 (for example, "Dipel ES®" from "Valent BioSciences, US"), Bacillus thuringiensis subsp.aizawai strain ABTS-1857 (for example) SD-1372, eg "XenTari®" from "Bayer Crop Science AG, DE"), Bacillus thuringiensis subsp.aizawai antigen type H-7 (eg, "Valent BioSciences") , US "" Florbac WG (registered trademark) "), Bacillus Bacillus thuringiensis subsp.aizawai strain GC-91, Bacillus thuringiensis subspecies. Aegypti (eg, "Agerin®"), Bacillus thuringiensis subspecies Bacillus thuringiensis subsp.tenebrionis strain NB 176 (SD-5428, for example, "Novodor FC®" from "BioFa DE"), Bacillus thuringiensis variant 7216 (Bacillus thuringiensis var. 7216) (for example). , "Amactic" and "Pethian"), Bacillus thuringiensis var. T36 (eg "Cahat"), Bacillus thuringiensis var. Colmeri (eg "Changzhou") "TianBaoBTc®" manufactured by Jianghai Chemical Factory), "M-One (registered trademark)" manufactured by "Bacillus thuringiensis var. San diego" (for example, "Bacillus thuringiensis var. San diego") Bacillus spp., Etc.; Bacillus bassiana strain (for example, "Naturalis (registered trademark)" manufactured by "Intrachem Bio Italia"), Beauveria bassiana strain CG716 ( For example, "BoveMax (registered trademark)" manufactured by "Novozymes"), F-263 (for example, "Biolisa Madara (registered trademark)" manufactured by "Idemitsu Kosan Co., Ltd."), Beauveria bassiana stock. Beauveria bassiana strain GHA (for example, "Botaniguard wettable powder (registered trademark)" manufactured by "ARYSTA"), Beauveria br ongniartii) (eg, "Beaupro®" from "Andermatt Biocontrol AG"), etc. (Beauveria spp.); Bradyrhizobium japonicum (eg, "Novozymes" from "Novozymes" Optimize®) ”); Burkholderia spp. Strain A396 (eg,“ MBI-206 TGAI® ”from“ Marrone Bio Innovations ”); Candida oleophila Strain I- 82 (eg, "Aspire®" from "Ecogen Inc., US"), Candida oleophila O strain (eg, "Nexy®" from "BioNext"), Candida. Candida saitoana (eg, "Biotechnology Research And Development Corporation"), Candida saitoana (eg, "Micro Flo Company, US (BASF SE)", "BIOCURE®" ) Etc. Candida spp.; Chaetomium cupreum (eg, "BIOKUPRUM TM (registered trademark)" from "AgriLife"), Chaetomium globosum (eg, "RIVale") "RIVadiom®"), etc. Chaetomium sp.; Chromobacterium subtsugae strain PRAA4-1T (MBI-203, eg, "Grandevo" from "Marrone Bio Innovations""Chromo-bacteriumsp.",Etc.; Cladosporium cladosporioides (eg, "Cladosporium cladosporioides"); chys rosea f. Catenulate strain J1446 (eg, "PRESTOP®" from "Verdera, Finland"); Colletotrichum gloeosporioides (eg, "Collego" from "Agriultural Research Initiat IVes") Coniothyrium spp., Such as Coniothyrium minitans strain CON / M / 91-08 (eg, "Contans®" from "Encore Technologies, LLC"); Cryptococcus albidus (eg, "Yield Plus®" from "Anchor Bio &#8722; Technologies, ZA"); Delftia acidovorans strain RAY209 (eg, "Brett Young Seeds") "BioBoost®"); Dilophosphora alopecuri (eg, "Twist Fungus®"); Drechsrela monoceras strain MTB-951 (eg, "Mitsui Kagaku Agro Co., Ltd." ) ”, Etc.,“ Drechsrela sp. ”); Entomophthora virulenta (eg,“ Ecomic ”,“ Vektor® ”); Fusarium oxysporum strain 101-2 (for example, "Marcarite" manufactured by "Esai Biosciences"), Fusarium oxysporum strain Fo47 (for example, "Fusaclean (registered trademark)" manufactured by "Natural Plant Protection") ) "), Etc. Fusarium spp.; Gliocladium catenulatum strain J1446 (eg," Prestop® "manufactured by" AgBio Inc. "), Gliocladium ro. Gliocladium roseum strain 321U (manufactured by "WF Stoneman Company LLC"), etc. Gliocladium sp.; Hirsutella thompsonii (eg, "Agro Bio &#8722; tech Research Center, IN""Mycohit®" and "ABTEC®"); Lactobacillus acidophilus (eg, "Fruitsan®" from "Inagrosa &#8722; Industrias Agrobiologicas, SA") , Lactobacillus plantarum strain BY (eg, "Lactobacillus wettable powder" manufactured by "Meiji Seika Pharma Co., Ltd."), Lactobacillus sp. Lactoplant®), etc. Lactobacillus sp.; Lecanicillium lecanii strain KV01 sprouting (eg, "Mycotal®" from "Koppert / Arysta"); Metalhizium anisopliae strain F52 (for example, "BIO 1020 (registered trademark)" manufactured by "Bayer Crop Science"), Metalhizium anisopliae strain SMZ-2000 ("Arista Life Science Co., Ltd.""PiratesGranules®"), Metalhizium anisopliae var. Acridum (eg, "Green Muscle®" from "Biological Control Products"), Metalhizium variant Acridum (Metarhizium) Anisopliae var. Acridum) (eg, "Green Guard®" from "Becker Underwood, US"), etc. Metalhizium spp.; Metschnikowia fructicola (eg, "Shemer®" from "Bayer Crop Science"); Microdochium dimerum (eg, "ANTIBOT®" from "Agrauxine, France") Microsphaeropsis ochracea (eg, "Microx®" from "Prophyta"); Monacrosporium phymatopagum from "Tomoe Chemical Industry Co., Ltd." (Registered Trademark) "); Mucor haemelis (eg," BioAvard® "from" Indore Biotech Inputs & Research "); Myrothecium verrucaria strain AARC-0255 (eg,""DiTeraTM®" from Valent Biosciences); Ophiostoma piliferum strain D97 (eg "Sylvanex"); Paecilomyces fumosoroseus strain apopka 97 (eg "Biobest""PreFeRal®WG"), Paecilomyces fumosoroseus strain FE 9901 (eg "No Fly®" from "Natural Industries Inc. (Novozymes company)"), Paecilomyces fumosoroseus) (for example, "Preferred Wettable Powder" manufactured by Tokai Bussan Co., Ltd.), Paecilomyces lilacinus strain 251 (for example, "BioAct WG (registered trademark)" manufactured by "Prophyta"), Paecilomyces Compositions containing Paecilomyces lilacinus (eg, "MELOCON®"), Paecilomyces te nuipes strain T1 (for example, "Gots A (registered trademark)" manufactured by "Idemitsu Kosan Co., Ltd."), Paecilomyces variotii strain Q-09 (for example, "Nemaquim" manufactured by "Quimia, MX") Paecilomyces spp., Etc.; Paenibacillus polymyxa strain AC-1 (“Topseed®” manufactured by “Green Biotech Company Ltd.”), Paenibacils popiliae (registered trademark) ”), etc. Paenibacillus poppiliae) (eg, "Milky spore disease®" from "St. Gabriel Laboratories"), etc. Paenibacillus spp.; Pasteuria nishizawa ("ClarIVa®" ), Pasteuria nishizawae (eg, "oyacyst LF / ST®" from "Pasteuria Bioscience"), Pasteuria penetrans (eg, "Pasteuria®" from "Pasteuria Bioscience") ) ”), Etc. Pasteuria spp.; Pectobacterium carotovorum (for example,“ Biokeeper® ”manufactured by Nissan Chemical Co., Ltd.), Pectobacterium carotovorum. (Pectobacterium carotovorum) CGE234M403 strain (eg, "Ecomate®" from "Kumiai Kagaku"); Pectobacterium spp.; Penicillium bilaii strain (eg, "Novozymes") "Jump Start®"); FOC PG B22 / SP1190 / 3.2 from Phlebiopsis gigantea (eg, "ROTSOP®" from "Verdera, Finland"); Homa Macrostroma ( Phoma macrostroma ) Strain 94-44B (eg, "Phoma H®" from "Scotts, US"); Pochonia chlamydosporia var. Catenulata (eg, "The National Center of Animal and Plant Health" (eg, "The National Center of Animal and Plant Health") CENSA); "KlamiC®" manufactured by CU "; Pseudomonas aureofaciens strain TX-1 (eg," Spot-Less Biofungicide® "manufactured by" Eco Soils Systems, CA " Pseudomonas chlororaphis strain 63-28 (eg, "ATEze®" from "EcoSoil Systems"), Pseudomonas chlororaphis strain MA 342 (eg, "Bioagri,""Cedomon®" made by "S"), Pseudomonas fluorescens strain 1629RS (eg "Frostban D®" made by "Frost Technology Corp"), Pseudomonas fluorescens (eg Pseudomonas fluorescens strain A506 (for example, "Blightban®" manufactured by "Blightban"), Pseudomonas fluorescens strain FPT-9601 ("Sanae Fuku" manufactured by "Taki Kagaku Co., Ltd." Sat (registered trademark) "), a mixture of Pseudomonas fluorescens strain FPT-9601 and strain FPH-9601 ("Cell seedling Genki (registered trademark) "manufactured by" Taki Kagaku Co., Ltd. ") , Pseudomonas fluorescens strain G7090 (eg, "Veggie Keeper®" from "Arista Life Sciences, Inc."), Pseudomonas proradix (eg, "Sourcon Padena") [Proradix®]), Pseudomo nas resinovorans (eg, "Solanacure®" from "Agricultural Research Council, SA"), Pseudomonas syringae strain MA-4 (eg, "Biosave®" from "EcoScience, US") ) "), Pseudomonas syringae strain 742RS (for example," Frost Technology Corp® "manufactured by" Frostban C "), Pseudomonas rhodesiae HAI-0804 strain ("Nippon Soda Co., Ltd. ) ”), Pseudomonas sp. Co., Ltd. CAB-02 (for example,“ Momigenki wettable powder ”manufactured by“ Nissan Chemical Industry Co., Ltd. ”), etc. Pseudomonas spp.; Pseudozyma aphidis (eg, "Yissum Research Development Company of the Hebrew UnIVersity of Jerusalem"), Pseudozyma flocculosa strain PF-A22 UL (eg, "Plant Products") "Sporodex L®" from "Co. Ltd, CA"), etc. Pseudozyma sp.; Pythium oligandrum strain DV74 or M1 (eg, "Bioprepraty, CZ" from "Bioprepraty, CZ"Polyversum®)); Reynoutria sachlinensis (eg, REGALIA® from Marrone Bio Innovations, US); Rhizopogon amylopogon (eg, Helena Chemical Company) "Myco-Sol®" manufactured by "Myco-Sol®"), Rhizopogon fulvigleba (for example, "Myco-Sol®" manufactured by "Helena Chemical Company" ) Etc. Rhizopogon spp.; Saccharomyces cerevisiae strain (eg, "Lesaffre et Compagnie, FR"); Streptomyces minor (eg, "Agrium Advanced Technologies"Sarritor®)); Serratia entomophila (eg, "Invade®" from "Wrightson Seeds"); Sporothrix insectorum (eg, "Biocerto;BR""SporothrixEs®"); Stagonospora phaseoli (commercially available from "Syngenta"); Streptomyces acidis cabies strain RL-110T (eg "Marrone") "MBI-005EP®" from Bioinnovations, CA "), Streptomyces candidus strain Y21007-2 (eg" BioBac® "from" Biontech, TW "), Streptomyces Streptomyces galbus strain K61 (eg, "Mycostop® from" Verdera "), Streptomyces lydicus strain WYEC108 (eg," Natural Industries, US "" ACTINOVATE®), Streptomyces saraceticus (eg, Streptomyces from A & A Group (Agro Chemical Corp.), Clanda®), etc. spp.); Talaromyces flavus strain B-422 (for example, "Momikeeper (registered trademark)" manufactured by "Central Glass Co., Ltd."), Talaromyces flavus strain. SAY-Y-94-01 (for example, "Tough Block (registered trademark)" manufactured by "Idemitsu Kosan Co., Ltd."), "PROTUS" manufactured by Talaromyces flavus strain V117b (for example, "Prophyta, DE") (Registered Trademark) WG "), etc. Talaromyces spp.; Thiobacillus sp. (For example," Cropaid® "manufactured by" Cropaid Ltd, UK "); Trichoderma album. ) (For example, a product known as "Bio-Zeid"), Trichoderma asperellum strain ICC 012 (manufactured by "Isagro"), Trichoderma asperellum strain T34 (eg, "Bioncontrol Technologies,""T34 Biocontrol (registered trademark)" manufactured by ES "), Trichoderma asperellum strain SKT-1 (for example," ECO-HOPE® "manufactured by" Kumiai Chemical Industry Co., Ltd. "), Trichoderma Trichoderma atroviride strain (eg, "EsquIVe® WP" from "Agrauxine, FR"), Trichoderma atroviride strain LC52 (eg, "Tenet" from "Agrimm Technologies Ltd, NZ") (Registered Trademark) ”), Trichoderma atroviride Co., Ltd. SKT-1 (for example,“ Eco Hope DJ® ”manufactured by“ Kumiai Chemical Industry Co., Ltd. ”), Trichoderma gamsii Co., Ltd. ICC 080 (For example, "BIO-TAMTM (registered trademark)" made by "Bayer Crop Science LP, US"), Trichoderma harzianum strain DB 103 (for example, "T-Gro 7456 (registered trademark) made by" Dagutat Biolab ") Trademark) ”), Trichoderma harzianum strain ITEM908 (eg,“ Ko ” "Trianum-P®" from "ppert"), Trichoderma harzianum strain KD (eg "Trichoplus®" from "Biological Control Products, SA"), Trichoderma harzianum) stock TH-35 (eg, "ROOT PRO®" from "Mycontrol Ltd."), Trichoderma harzianum rifai stock T-22 (KRL &#8722; AG2), for example, ""PLANT SHIELD T-22G (registered trademark)" manufactured by Firma BioWorks Inc. US), "TRICHODEX (registered trademark) manufactured by Trichoderma harzianum rifai" (for example, "Makhteshim Ltd, US") ) ”), Trichoderma lignorum strain TL-0601 (eg,“ Mycotric® ”manufactured by“ Futureco Bioscience, ES ”), Trichoderma polysporum strain (eg,“ BINAB Bio- "Binab TF WP®" from Innovation AB, Sweden), Trichoderma stromaticum (eg "TRICOVAB®" from "Ceplac;Brazil"), Trichoderma virens ) (Also known as "Gliocladium virens") Strain GL-21 (eg, "SOILGARD®" from "Certis LLC, US"), Trichoderma viride ) Stock ICC080 (for example, "REMEDIER® WP" manufactured by "Isagro Ricerca, ITALIA"
), Trichoderma viride strain TV1 (eg, "Trianum &#8722;P®" from "Koppert"), etc. Trichoderma spp.; Tsukamurella paurometabola Strain C-924 (eg, "HeberNem®"); Ulocladium oudemansii Strain HRU3 (eg, "Botry-Zen®" from "Botry-Zen Ltd, NZ"); Vario Variovorax paradoxus strain CGF4526 (for example, "Fieldkeeper wettable powder (registered trademark)" manufactured by "Central Glass"); VA ((Vesicular-Arbuscular Mycorrhiza) mycorrhiza (manufactured by "Idemitsu Agri") "Dr Kincon®"); Verticillium alboatrum strain WCS850 (eg, "Dutch Trig®" from "Tree Care Innovations"), Verticillium lecanii IMI 179172 (for example, "Verticillium lecanii" manufactured by "Arista Life Science Co., Ltd."), Verticillium lecanii stock IMI 263817 (for example, "Arista Life Science Co., Ltd.""Mycotal®"), etc., Verticillium spp.; Xanthomonas campestris (available from Camperico Liquid (registered trademark) Taki Kagaku); etc. may be used in combination. It is possible.

The pesticide active ingredient used in the pesticide granular composition of the present invention is in a proportion of 0.01 to 50.0% by mass, preferably 0.2 to 10.0% by mass, based on the total weight of the pharmaceutical product. It can be appropriately selected from the ratio.

The surfactant suitable for use in the present invention can be any known in the art. Examples of the surfactant used as a dispersant / wetting agent / spreading agent / spreading agent include nonionic surfactants; polyoxyethylene lauryl ether, polyoxyethylene cetyl ether, polyoxyethylene stearyl ether, and the like. Polyoxyethylene oleyl ether, polyoxyethylene myristyl ether, polyoxyethylene octyldodecyl ether, polyoxyethylene tridecyl ether, polyoxyethylene isodecyl ether, polyoxyethylene naphthyl ether, polyoxyethylene isostearyl ether, polyoxyethylene phenyl Ether, polyoxyethylene behenyl ether, polyoxyethylene cholesteryl ether, polyoxyethylene polyoxypropylene butyl ether, polyoxyethylene polyoxypropylene lauryl ether, polyoxyethylene polyoxypropylene cetyl ether, polyoxyethylene polyoxypropylene stearyl ether, poly Polyoxy such as oxyethylene polyoxypropylene decyltetradecyl ether, polyoxypropylene butyl ether, polyoxypropylene myristyl ether, polyoxypropylene cetyl ether, polyoxypropylene stearyl ether, polyoxypropylene lanolin alcohol ether, polyoxyethylene oleylcetyl ether, etc. Polyoxyalkylene alkyl ethers such as alkylene branched decyl ethers, polyoxyalkylene tridecyl ethers, polyoxyalkylene lauryl ethers; special formulations of alkylene oxide derivatives; polyether polyols; phenoxyethanol; acetylene diols; polyoxyalkylene-added acetylene diols; sorbitan Fatty acid ester, polyoxyethylene sorbitan fatty acid ester, sucrose fatty acid ester, polyoxyethylene fatty acid ester, polyoxyethylene fatty acid diester, polyoxyalkylene sorbitol fatty acid ester (for example, polyoxyethylene sorbitol fatty acid ester, etc.), sorbitan sesquiolate, sorbitan mono Fatty acid esters such as oleate, polyoxyethylene sorbitan monococoate, polyoxyethylene sorbitan monostearate, polyoxyethylene sorbitan monooleate, glycerin fatty acid esters; polyoxyethylene resin acid esters; polyoxyethylene distearate esthetics Le; Polyoxyethylene oleic acid ester; Polyoxyethylene glyceryl isostearate; Polyoxyethylene alkylaryl ether; Polyoxyethylene alkylphenyl ether such as polyoxyethylene styrenated phenyl ether; Polyoxyethylene dialkylphenyl ether; Polyoxybisphenyl Ether; Polyoxyethylene polyoxypropylene glycol, polyoxyethylene polyoxypropylene block copolymer, polystyrene polyoxyethylene block polymer, alkylpolyoxyethylene / polyoxypropylene block polymer ether, alkylpolyoxyethylene / polypropylene block copolymer ether, alkylphenyl Polyoxyethylene / polyoxypropylene block polymer type nonionic surfactant such as polyoxyethylene / polyoxypropylene block polymer ether; polyoxyethylene alkylamine; alkylphenylpolyoxyethylene / polyoxypropylene block polymer ether, polyoxy Polymer surfactants such as ethylene alkylphenyl ether formalin condensates; octylpolyglucoside; butylpolyglucoside; sucrose benzoic acid ester; sucrose acetate: polyoxyethylene alkylamine; polyoxyethylene fatty acid amide; polyoxyethylene fatty acid Bisphenyl ether; Polyaromatic ring-type nonionic surfactant such as polyoxyalkylene benzyl phenyl ether and polyoxyalkylene styryl phenyl ether; Acetylene diol; Polyoxyalkylene-added acetylene diol such as polyoxyethylene alkane diol; Fatty acid glycol ether Polyalkylene polyamine alkylene oxide adduct; Polyalkylene polyimine alkylene oxide adduct; Polyvinylpyrrolidone; Silicone-type nonionic surfactants such as polyoxyethylene ether-type silicones and polyoxyethylene ester-type silicones; Fluorine-based surfactants ; Hardened castor oil; Polyoxyalkylene castor oil such as polyoxyethylene castor oil; Palm oil fatty acid diethanolamide; Polyoxyalkylene cured castor oil such as polyoxyethylene cured castor oil.

As an ionic surfactant suitable for use in the present invention, anionic surfactants include, for example, alkyl sulfates such as lauryl sulfate; sodium polyoxyalkylene branched decyl ether sulfate, polyoxyethylene isodecyl ether ammonium sulfate, and poly. Polyoxyalkylene alkyl ether sulfates such as sodium oxyethylene tridecyl ether sulfate, sodium polyoxyethylene lauryl ether sulfate, ammonium polyoxyethylene lauryl ether sulfate, sodium polyoxyethylene alkyl ether sulfate, sodium polyoxyethylene oleylcetyl ether sulfate; Polyoxyalkylene alkylphenyl ether sulfates such as polyoxyethylene alkylphenyl ether sulfates, polyoxyethylene styrene phenyl ether ammonium sulfates, and polyoxyethylene styrylphenyl ether sulfates; sulfuric acids such as alkyl sulfates and alkyl ether sulfates. Ester-type anionic surfactant; polyoxyalkylene alkyl ether acetate such as polyoxyethylene lauryl ether acetate; sodium linear alkylbenzene sulfonate, sodium alphaolefin sulfonate, sodium decylbenzene sulfonate, undecylbenzene sulfonic acid Sodium, sodium dodecylbenzene sulfonate, sodium tridecylbenzene sulfonate, sodium tetradecylbenzene sulfonate, calcium decylbenzene sulfonate, calcium undecylbenzene sulfonate, calcium dodecylbenzene sulfonate, calcium tridecylbenzene sulfonate, tetradecyl Alkylbenzene sulfonate anionic surfactants such as calcium benzene sulfonate; linear alkylbenzene sulfonic acid, alkylaryl sulfonate, lignin sulfonate, phenol sulfonic acid, naphthalene sulfonate; monoalkyl naphthalene sulfonate, Alkylnaphthalene sulfonate such as dialkylnaphthalene sulfonate; salt of formalin condensate of naphthalene sulfonic acid; formalin condensate of alkylnaphthalene sulfonate; alkyldiphenyl ether dissulfonate; polyoxyethylene alkyl ether phosphate potassium salt, polyoxy Polyoxyethylene alkyl ethers such as ethylene alkyl ether phosphate sodium salt Phosphate; polyoxyethylene dialkylphenyl ether phosphate, alpha olefin sulfonate, alkylnaphthalene sulfonate, alkyldiphenyl ether disulfonate, alkane sulfonate, paraffin sulfonate, other sulfonic acid type anionic surface activity Agents; Dialkyl sulfosuccinate; Alkyl sulfosuccinates; Dialkyl sulfosuccinates such as sodium dioctyl sulfosuccinate; Phenol sulfonic acid; Alkyl sulfates such as sodium lauryl sulfate; Triethanolamine uryl sulfate; Ammonium lauryl sulfate; Polyoxyethylene alkyl Polyoxyalkylene alkyl ether phosphoric acid esters such as ether phosphoric acid ester, polyoxyethylene lauryl ether phosphoric acid ester, polyoxyethylene tridecyl ether phosphoric acid ester; polyoxyethylene alkyl ether phosphoric acid ester / monoethanolamine salt, polyoxy Ethylene lauryl ether phosphoric acid ester / monoethanolamine salt; polyoxyalkylene alkyl phenyl ether phosphoric acid ester such as polyoxyethylene styrene phenyl ether phosphoric acid ester; polyoxyethylene dialkyl phenyl ether phosphoric acid ester; polyoxyethylene styryl phenyl ether Phosphate ester; Polyoxyethylene / polyoxypropylene block polymer Phosphate ester; Alkyl phosphate ester salt; Polydialyldimethylammonium chloride; Phosphate-type anionic surfactant; Disodium lauryl sulfosuccinate, Polyoxyethylene sulfosuccinate lauryl Disodium, polyoxyethylene alkyl sulfosuccinate lauryl disodium, polyoxyethylene alkyl sulfosuccinate disodium, other carboxylic acid type anionic surfactants; alkyl phosphates sodium, alkyl phosphates / monoethanolamine salts; poly Polyoxyalkylene alkyl phenyl ether phosphates such as oxyethylene styrylphenyl ether phosphate; polyoxyethylene / polyoxypropylene block polymer phosphate; polyoxyethylene / polyoxypropylene block polymer sulfate; sodium fatty acid, potassium fatty acid, ammonium fatty acid Ethereal salts such as; resin acid salts such as sodium resinate and potassium resinate; polycarboxylic Acid metal salt; styrene-maleic acid copolymer ammonium salt; styrene-maleic acid half ester copolymer ammonium salt; sodium carboxymethyl cellulose; sodium polyacrylate, polyacrylic acid salt such as ammonium polyacrylate; N-methyl-fatty acid sarcosinate; etc. Can be mentioned. In particular, alkyl sulfates, formalin condensates of alkylnaphthalene sulfonates, polyoxyethylene alkyl ether phosphate potassium salts, polyoxyethylene allylphenyl ether phosphate amine salts, dialkyl sulfosuccinates, polycarboxylic acid metal salts, alpha olein sulfonic acid. Sodium is preferred.

For cationic surfactants, for example, alkylamine salts such as laurylamine hydrochloride, stearylamine hydrochloride, oleylamine hydrochloride; alkylamine acetates such as rustearylamine acetate and stearylaminopropylamine acetate; octyldimethylethylammonium ethyl. Alkyldimethylethylammonium sulfates such as sulfates, lauryldimethylethylammonium ethyl sulfates, palmityldimethylethylammonium ethyl sulfates; monoalkylmethylated ammonium chlorides, dialkylmethylated ammonium chlorides, lauryltrimethylammonium chlorides, cetyltrimethylammoniums. Alkylmethylammonium chlorides such as chlorides, stearyltrimethylammonium chlorides, didecyldimethylammonium chlorides, lauryldimethylbenzylammonium chlorides; alkylpentamethylpropylenediamine chlorides; methylpolyoxyethylenealkylammonium chlorides; octylphenoxy. Ethoxyethyldimethylbenzylammonium chloride; alkyl N-methylpyridinium bromide; stearyldimethylhydroxyethylammonium paratoluenesulfonate; stearyldimethylaminopropylamide; other alkylamine salts; alkylpentamethylpropylenediamine chloride; lauryldimethylaminoacetic acid betaine; coconut oil Fatty acid amide propyl betaine; octanoic acid amide propyl betaine; lauryl dimethylamine oxide; alkyldimethylbenzalconium chloride, benzethonium chloride, octylphenoxyethoxyethyldimethylbenzylammonium chloride, tributylbenzylammonium chloride, benzethonium chloride and other benzalconium-type cationic properties. Examples include surfactants.

Examples of the amphoteric surfactant such as amino acid type or betaine type include dialkyldiaminoethyl betaine, alkyldimethylbenzyl betaine, alkyldimethylaminoacetic acid betaine, coconut oil fatty acid amide propyl betaine, octanoic acid amide propyl betaine, and alkyldimethylamine oxide. Can be mentioned. These surfactants may be used alone or in combination of two or more.

The surfactant used in the pesticide granular composition of the present invention has a ratio of 0.10 to 20.0% by mass, preferably 0.5 to 10.0% by mass, based on the total weight of the pharmaceutical product. Can be appropriately selected from.

Secondary materials used in the pesticide granular composition of the present invention include solid carriers, binders, tackifiers, colorants, anti-caking agents, disintegrants, decomposition inhibitors, defoamers, pH adjusters, and light. Examples include agents such as stabilizers. In addition, if necessary, preservatives, fungicides, plant pieces and the like may be used as additive components. These additive components may be used alone or in combination of two or more.

The solid support suitable for use in the present invention is an inert carrier and can be any known in the art. For example, alumina, zirconia, sardine clay, acidic white clay, kaolinite, kaolin, calcium bentonite, chromite sand, silica sand, silica sand silica, zirconium silicate, silicate powder, diatomaceous soil, aluminum nitride, barium carbonate, saponite, choremanite, calcined diatomaceous soil, Natural minerals such as diatomaceous soil, silas, silus balloon, silicon carbide, zircon sand, zircon, zircon flower, aluminum hydroxide, zeolite, quartz, quartz glass powder, sodium bentnite, sodium montmorillonite, long stone powder, pottery stone , Halosite, borosand, magnesia, wood knot clay, wax stone, pearlite, cement, mica, clay, kaolin clay, talc, stone brush stone, soap stone, glass beads, alumina, calcium carbonate, silica ash stone, wallastnite, light Calcium carbonate, synthetic hydrotalcite, synthetic mica, calcium carbonate (heavy calcium carbonate, light calcium carbonate), calcined clay, silk powder, slaked lime, kaolinite, serinite, ultrafine zinc oxide, precipitated barium sulfate, dolomite powder, Inorganic salts such as nylon powder, ammonium sulfate, sodium sulfate, barium sulfate, fine particle aluminum hydroxide, polyethylene wax, organic bentnite, molten silica, brazing stone, pyrophyllite, talc, attapulsite, potassium chloride, hydrous silicic acid (synthetic silicic acid, Organic solid carriers such as synthetic silicate), starch, cellulose, plant powder (eg, shavings, coconut husks, corn stalks, tobacco stalks, etc.), plastic carriers such as polyethylene, polypropylene, polystyrene, polyvinyl chloride, polyethylene terephthalatene, etc. Examples include urea, inorganic hollow body, plastic hollow body, fumed silica (white carbon) and the like. These may be used alone or in combination of two or more. In particular, calcium carbonate, hydrous silicic acid, calcined diatomaceous earth, and clay are preferable. The solid carrier used in the pesticide granular composition of the present invention can be appropriately selected from a ratio of 0.50 to 98.0% by mass based on the total weight of the pharmaceutical product.

The water-soluble organic solvent used in the pesticide granular composition of the present invention is a water-soluble organic solvent usually used for pesticide preparations, and it is preferable that the solvent is hard to volatilize by itself. For example, alcohols such as polyhydric alcohols such as ethylene glycol, diethylene glycol, propylene glycol, glycerin, hexylene glycol, 2-ethylhexyl diglycol, polyethylene glycol, polypropylene glycol, glycerin; polyhydric alcohol compounds such as propylene glycol ether. Classes; ketones such as acetone, methyl ethyl ketone, methyl isobutyl ketone, diisobutyl ketone, cyclohexanone; ethers such as ethyl ether, dioxane, ethylene glycol monoethyl ether, dipropyl ether, tetrahydrofuran; non-polyoxyalkylene-added acetylene diols. Ionic surfactants; N-methyl-2-pyrrolidone, dimethylsulfoxide, formamide, dimethylformamide, dimethylacetamide, dimethylacrylamide and the like can be mentioned. Ethylene glycol, diethylene glycol, propylene glycol, glycerin, 2-ethylhexyl diglycol, polyethylene glycol, or N-methyl-2-pyrrolidone is preferable, and ethylene glycol and propylene glycol are particularly preferable. These may be used alone or in combination of two or more. The water-soluble organic solvent preferably impregnates the granulated body after mixing, kneading, granulating and drying a composition containing a pesticide active ingredient, a solid carrier, and a surfactant. The water-soluble organic solvent used is used alone or as a mixed solvent with water, and the mixing ratio of the water-soluble organic solvent: water when used as a mixed solvent is 100: 0 to 75:25. Any amount of the water-soluble organic solvent can be added to the molded granulation body, and the addition ratio of the water-soluble organic solvent to the granulation body is the total weight of the pesticide granular composition of the present application. It is 0.2 to 15% by mass, and particularly preferably 0.5 to 10% by mass.

Examples of the binder or tackifier include carboxymethyl cellulose and its salts, dextrin, water-soluble starch, xanthan gum, guar gum, citrus sugar, polyvinylpyrrolidone, arabic rubber, polyvinyl alcohol, polyvinylacetate, sodium polyacrylate, and an average molecular weight of 6000 to 20000. Polyethylene glycol, polyethylene oxide with an average molecular weight of 100,000 to 5 million, phospholipids (eg, cephalin, lecithin, etc.), cellulose powder, dextrin, processed starch, polyaminocarboxylic acid chelate compound, crosslinked polyvinylpyrrolidone, maleic acid and styrenes. Polymer, (meth) acrylic acid-based copolymer, half-ester of polymer composed of polyhydric alcohol and dicarboxylic acid anhydride, water-soluble salt of polystyrene sulfonic acid, paraffin, terpene, polyamide resin, polyacrylic acid salt, poly Examples thereof include oxyethylene, wax, polyvinylalkyl ether, alkylphenol formalin condensate, synthetic resin emulsion and the like. These may be used alone or in combination of two or more.

Examples of the colorant include inorganic pigments such as iron oxide, titanium oxide and Prussian blue, organic dyes such as alizarin dyes, azo dyes and metallic phthalocyanine dyes, and organic pigments such as phthalocyanine blue and permanent red. Be done.

Auxiliary agents for preventing caking and promoting disintegration include, for example, polysaccharides such as starch, alginic acid, mannose, and galactose, polyvinylpyrrolidone, fumed silica (white carbon), ester gum, petroleum resin, and sodium tripolyphosphate. , Sodium hexametaphosphate, metal stearate, cellulose powder, dextrin, copolymer of methacrylic acid ester, polyvinylpyrrolidone, polyaminocarboxylic acid chelate compound, sulfonated styrene / isobutylene / maleic anhydride copolymer, starch / polyacrylonitrile graft Examples thereof include copolymers. These may be used alone or in combination of two or more.

Examples of the decomposition inhibitor include desiccants such as zeolite, raw lime and magnesium oxide, antioxidants such as phenol compounds, amine compounds, sulfur compounds and phosphoric acid compounds, salicylic acid compounds and ultraviolet absorbers of benzophenone compounds. Be done. Examples of the preservative include potassium sorbate, 1,2-benzothiazolin-3-one and the like. These may be used alone or in combination of two or more.

Antifoaming agents include silica, silicone (oil type, oil compound type, self-emulsifying type, emulsion type, solution type), polydialkylsiloxane, polydimethylsiloxane, fluoroaliphatic ester, perfluoroalkylphosphonic acid / perfluoroalkylphosphonic acid. Or their salts and mixtures thereof, etc. These may be used alone or in combination of two or more.

Examples of the pH adjusting agent include various inorganic acids and organic acids such as hydrochloric acid, sulfuric acid, phosphoric acid, sulfonic acid and carboxylic acid, and a method of adding a predetermined amount of salts and esters thereof to the composition of the present invention. Specific examples of the organic acid include acidic phosphoric acid ester, citric acid, maleic acid, sorbic acid, lactic acid and tartaric acid. In addition, various buffer solutions such as hydrogen phosphate 2 sodium-citric acid aqueous solution, sodium acetate-hydrochloric acid aqueous solution, formic acid-sodium formate aqueous solution, lactic acid-sodium lactate aqueous solution, tartrate acid-sodium tartrate aqueous solution and sodium citrate-hydrochloric acid aqueous solution are placed. The pH can be controlled by adding a fixed amount.

Examples of the light stabilizer include titanium oxide, yellow iron oxide, brown iron oxide, iron sesquioxide (ferrous oxide), yellow iron sesquioxide, and the like.

Further, if necessary, a functional spreading agent, an activity enhancer such as a metabolic decomposition inhibitor such as piperonyl butoxide, an epoxidized animal oil or vegetable oil such as epoxidized soybean oil, an antioxidant such as BHT, and an ultraviolet absorber. Other auxiliaries such as etc. can also be used.

Next, a method of applying the granular pesticide composition of the present invention will be described. The pesticide granular composition of the present invention is used for controlling pests or controlling the growth of plants depending on the pesticide active ingredient contained. When the pesticide active ingredient contained in the granular composition of the pesticide of the present invention is for paddy rice, it can be used as, for example, a fungicide for paddy rice, an insecticide for paddy rice, and a herbicide for paddy rice.

When the pesticide granular composition of the present invention is applied to paddy rice, it may be applied to rice seeds, a seedling raising medium, or a paddy field or a dry field. The rice seeds referred to here mean rice seeds in a state before sowing in soil such as paddy fields. Examples of the paddy field include a paddy field that is flooded or flooded, and a paddy field that is flooded is a state in which water is cultivated, watered, puddled, etc., and then further watered as necessary. Refers to the paddy field. Further, the paddy field in a flooded state means a paddy field in which the water content is maintained at the same level as the flooded state by performing a waterfall treatment from the flooded state and the soil surface is exposed.

The rice seeds to which the pesticide granular composition of the present invention is applied can be cultivated by directly sowing in dry fields, wet fields, and paddy fields, or may be sown and cultivated in a nursery medium such as a nursery box. The seedling raising medium is not particularly limited as long as it is a soil for raising rice seedlings, and a seedling raising mat seedling raising box, a paddy rice seedling raising tray or a nursery bed other than the soil may be used, or the seedlings may be cultivated by pool raising.

When the pesticide granular composition of the present invention is applied to a nursery box for paddy rice, it can also be applied by mixing with hilling soil, and can be mixed with floor soil, covered soil, or mixed with the entire hilling soil. The time of application at the time of sowing may be before, at the same time, or after sowing, or may be applied after soil covering. In the field of paddy fields, water surface application such as granules to paddy fields is often used. The time of application is not particularly limited as long as it is the period from the time of sowing to the time of transplantation. Examples include bed soil mixing treatment, soil covering mixing treatment at the time of sowing, greening period treatment, transplantation day treatment, and transplantation simultaneous treatment. It may be applied from 7 days before transplantation to the day before transplantation, and can be applied at any time during the period from seeding to transplantation. The period from sowing to transplantation depends on the seedlings (seedlings around the 2.5 leaf stage), medium seedlings (seedlings around the 3.5 leaf stage) or adult seedlings (seedlings around the 4.5 leaf stage). The seedling raising period varies depending on the weather conditions, but it can be applied in any case.

As a method of applying the pesticide granular composition of the present invention to paddy fields, a method of applying it to paddy fields as it is or by formulating it, a method of applying it to paddy soil during direct sowing cultivation, and a flooded state. The method of applying to the water surface of the paddy field can be mentioned. When it is applied to the leaves of rice stalks, it may be applied at any time from the seedling raising period to the harvest. The method of application to paddy fields is not particularly limited, but it is usually sprayed to paddy fields that are flooded.

The pesticide granular composition of the present invention is used, for example, by directly spraying it on a water surface application in a paddy field, soil mixing in a field, a nursery box or the like using a power sprayer or the like. Power spreaders can be particularly commonly used equipment, such as punkle sprayers, manned helicopters, radio-controlled helicopters, radio-controlled boats, drones, one-shot spreaders, power (manual or automatic) spreaders, carry-type power spreaders, A backpack type power spreader, a manual type spreader, etc. can be used. Alternatively, it may be sprayed by hand without using a device. The application rate of the pesticide granular composition of the present invention is, for example, in the range of 0.5 to 4.0 kg per 10 ares.

As a method of applying the pesticide granular composition of the present invention to paddy soil, a method of treating the entire surface of paddy soil (full surface treatment), a method of treating a groove provided when sowing rice (sowing groove treatment), and a method of treating rice Examples thereof include a method of treating directly above (0 to 10 cm) or directly below (0 to 10 cm) of the seed, a method of treating the rice plant or the vicinity of the seed in a streak or dot shape (side-row treatment), and the like. When applied to paddy soil, it can be mixed with agricultural materials such as paste fertilizer and granular fertilizer, or applied at the same time. The time to apply this composition may be before sowing or transplanting of rice, at the same time as sowing or transplanting, or immediately after sowing or immediately after transplanting. When it is applied at the same time as seeding or transplanting, it may be applied using an attachment attached to the seeding machine or the transplanting machine, or may be applied by other methods. Further, in the case of full-scale treatment, the period from sowing or transplanting to water injection, the mid-drying period, or the intermittent irrigation period may be used. When the pest control agent composition of the present invention is used, the soil surface of the paddy field may be dry, or the soil surface is moist but not flooded (water depth 0 cm). May be good. When applied to the surface of a flooded paddy field, it may be applied at any time during the period from sowing or transplanting to harvesting, as long as the water depth is maintained by normal rice management.

When the pesticide granular composition of the present invention is used for herbicidal treatment, it can be treated on the target crop and / or in the vicinity where the target crop is cultivated. Therefore, the composition of the present invention may be applied, for example, to a region where useful plants grow, and may be applied by a commonly used method such as foliage application, soil application, or the like. The application time is not particularly limited as long as it does not interfere with the effect of the present invention, and may be from before the emergence of useful plants to the growing season, before the emergence of weeds, the germination stage, the growing season and the like. For spraying on the soil (soil application), spray on the soil surface before the emergence of useful plants and before the emergence of weeds, and spray on the soil surface from above after the emergence of useful plants and before the emergence of weeds. Specific examples thereof include spraying on the soil surface between furrows or between strains after germination and before weeds, or spraying on the soil surface from above after germination of useful plants and after weeds emerge. In addition, in order to spray the composition of the present invention on the plants of weeds to be controlled (application of foliage), it is sprayed on the foliage of weeds from above before the emergence of useful plants and after the emergence of weeds, or the emergence of useful plants. Specific examples thereof include spraying the weeds on the foliage of the weeds from above after the weeds have sprung up.

The pesticide granular composition of the present invention can exhibit a desired pest control effect even when a preparation containing a single active ingredient is mixed in the field and treated by the above-mentioned treatment method. Further, even if the individual formulations are treated by the above-mentioned treatment method at the same time, the desired pest control effect can be exhibited. Here, the same period does not only mean that the processes are performed at exactly the same time, but it can be regarded as the same period within a period of about one week, and different processing methods can be adopted for each. Furthermore, the desired pest control effect can also be exhibited by treating each of the individual formulations by the above-mentioned treatment method at intervals. The treatment interval at this time is not particularly limited as long as the effect of the present invention can be exhibited, but in general, it is preferably within 3 months, and particularly preferably within 2 months from the treatment of each individual pharmaceutical product. .. At this time, either active ingredient may be treated first, or different treatment methods may be adopted for each.

The pesticide granular composition of the present invention can also be used as a pest control agent other than farmland, for example, cutting traces, fallow fields, ridges, farm roads, waterways, pastures, graveyards, parks, roads. It can also be used for the extermination of general weeds such as athletic fields, vacant lots around buildings, cleared land, railroad ends, or forests. In this case, it is economically most effective to treat the weeds by the beginning of the outbreak, but the present invention is not limited to this, and it is possible to control weeds and the like in the growing season.

Representative examples and test examples of the present invention are shown below, but the present invention is not limited thereto. In the examples, "parts" means "parts by mass" (that is, W / W%).

Example 1. Granules-1
0.51 parts of penox slam, 2.02 parts of benzobicyclon, 0.69 parts of POE alkyl ether phosphate potassium salt, 3.96 parts of polycarboxylic acid metal salt, 92.32 parts of calcium carbonate, 0.50 parts of hydrous silicic acid. Granules used as a base were prepared by uniformly mixing and granulating. 1.00 part of propylene glycol was impregnated into 99.00 parts of the granule base, and the granules were sized to obtain the granule of the present invention.

Example 2. Granules-2
Pyracronyl 1.52 parts, oxadichromephone 0.31 parts, sodium alphaolein sulfonate 0.50 parts, polycarboxylic acid metal salt 3.70 parts, dialkylsulfosuccinate 0.02 parts, polyoxyethylene allylphenyl ether phosphate amine salt 0.04 parts, 93.41 parts of calcium carbonate, and 0.50 parts of hydrous sulfonic acid were uniformly mixed and granulated to prepare a granule as a base. The granules were impregnated with 99.00 parts of the granule base and 1.00 parts of propylene glycol, and the granules were sized to obtain the granules of the present invention.

Example 3. Granules-3
0.51 parts of penox slam, 2.02 parts of benzobicyclon, 0.69 parts of POE alkyl ether phosphate potassium salt, 3.96 parts of polycarboxylic acid metal salt, 92.32 parts of calcium carbonate, 0.50 parts of hydrous silicic acid. Granules used as a base were prepared by uniformly mixing and granulating. 98.00 parts of the granule base was impregnated with 2.00 parts of propylene glycol and sized to obtain the granule of the present invention.

Example 4. Granules-4
2.54 parts of ipphencarbazone, 0.91 part of imazosulfone, 2.02 parts of benzobicyclon, 0.50 part of sodium alphaolein sulfonate, 3.66 parts of polycarboxylic acid metal salt, 0.13 part of dialkylsulfosuccinate. Part, 1.00 part of alkyl sulfate, 7.92 part of calcined diatomaceous soil, 80.82 part of calcium carbonate, and 0.50 part of hydrous silicate were uniformly mixed and granulated to prepare a granule as a base. The granules were impregnated with 99.00 parts of the granule base, 0.95 parts of propylene glycol and 0.05 parts of water, and the granules were sized to obtain the granules of the present invention.

Example 5. Granules-5
0.51 parts of penox slam, 2.02 parts of benzobicyclon, 0.69 parts of POE alkyl ether phosphate potassium salt, 3.96 parts of polycarboxylic acid metal salt, 92.32 parts of calcium carbonate, 0.50 parts of hydrous silicic acid. Granules used as a base were prepared by uniformly mixing and granulating. 99.50 parts of the granule base was impregnated with 0.50 part of propylene glycol and granulated to obtain the granule of the present invention.

As Comparative Example 1, a granulated granule composition containing no propylene glycol was prepared.
0.51 parts of penox slam, 2.02 parts of benzobicyclon, 0.69 parts of POE alkyl ether phosphate potassium salt, 3.96 parts of polycarboxylic acid metal salt, 92.32 parts of calcium carbonate, 0.50 parts of hydrous silicic acid. Granules used as a base were prepared by uniformly mixing and granulating.

As Comparative Example 2, a granulated granule composition containing no propylene glycol was prepared.
Pyracronyl 1.52 parts, oxadichromephone 0.31 parts, sodium alphaolein sulfonate 0.50 parts, polycarboxylic acid metal salt 3.70 parts, dialkylsulfosuccinate 0.02 parts, polyoxyethylene allylphenyl ether phosphate amine salt 0.04 part, 93.41 part of calcium carbonate and 0.50 part of hydrous sulfonic acid were uniformly mixed and granulated to prepare a granule as a base.

Test Example 1 (Comparative test of powdering property)
In this test, 5 g of the sample was placed in a glass bottle having a capacity of 100 mL, covered, and vigorously shaken up and down 20 times and allowed to stand. Then, the state of the planktonic particles was visually confirmed, and the powdering was evaluated depending on the addition ratio of the water-soluble organic solvent. Table 1 shows the criteria for the powdering test with the naked eye, and Table 2 shows the test results. As is understood from the test results, the powdering property of Examples 1 to 3 was reduced.

Claims (11)

A pesticide granular composition containing a pesticide active ingredient, a solid carrier, a surfactant, and a water-soluble organic solvent. One or more agents selected from the group consisting of binders, tackifiers, colorants, anti-caking agents, disintegrants, antioxidants, defoamers, pH regulators and light stabilizers. The pesticide granular composition according to claim 1, further comprising. The pesticide granular composition according to claim 1 or 2, wherein the pesticide active ingredient is one or more selected from ipfencarbazone, imazosulfuron, penokislam, benzobicyclon, oxadichromephone and pyracronyl. The pesticide granular composition according to any one of claims 1 to 3, wherein the pesticide active ingredient is one or more selected from penoxislam and benzobicyclon. The pesticide granular composition according to any one of claims 1 to 3, wherein the pesticide active ingredient is one or more selected from oxadichromephon and pyracronyl. The pesticide granular composition according to any one of claims 1 to 3, wherein the pesticide active ingredient is one or more selected from ipfencarbazone, imazosulfuron and benzobicyclon. The pesticide granular composition according to any one of claims 1 to 6, wherein the solid carrier is one or more selected from calcium carbonate, hydrous silicic acid, calcined diatomaceous earth and clay. Surfactants are alkyl sulfates, formalin condensates of alkylnaphthalene sulfonates, polyoxyethylene alkyl ether phosphate potassium salts, polyoxyethylene allylphenyl ether phosphate amine salts, dialkyl sulfosuccinates, polycarboxylic acid metal salts and alpha. The pesticide granular composition according to any one of claims 1 to 7, which is one or more selected from sodium oleinsulfonate. The pesticide granular composition according to any one of claims 1 to 8, wherein the water-soluble organic solvent is ethylene glycol, propylene glycol, polyethylene glycol or polypropylene glycol. Claims 1 to 9 include a step of kneading, granulating, and drying a composition containing a pesticide active ingredient, a solid carrier, and a surfactant, and then impregnating the granulated product with a water-soluble organic solvent. The method for producing a pesticide granular composition according to any one of the above items. The method for producing a pesticide granular composition according to claim 10, wherein the content of the water-soluble organic solvent is 0.5 to 10% by mass of the total amount of the pesticide granular composition.