JP2022070954A - 医療デバイスの複数の電極間のインピーダンスを測定するためのシステム - Google Patents
医療デバイスの複数の電極間のインピーダンスを測定するためのシステム Download PDFInfo
- Publication number
- JP2022070954A JP2022070954A JP2022019596A JP2022019596A JP2022070954A JP 2022070954 A JP2022070954 A JP 2022070954A JP 2022019596 A JP2022019596 A JP 2022019596A JP 2022019596 A JP2022019596 A JP 2022019596A JP 2022070954 A JP2022070954 A JP 2022070954A
- Authority
- JP
- Japan
- Prior art keywords
- electrodes
- drive signals
- frequency
- electronic control
- control device
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 230000004044 response Effects 0.000 claims abstract description 52
- 238000000034 method Methods 0.000 claims abstract description 45
- 230000001360 synchronised effect Effects 0.000 claims abstract description 25
- 238000005259 measurement Methods 0.000 claims description 22
- 238000005070 sampling Methods 0.000 claims description 15
- 239000002131 composite material Substances 0.000 claims description 4
- 238000012545 processing Methods 0.000 abstract description 8
- 230000008569 process Effects 0.000 description 13
- 238000001514 detection method Methods 0.000 description 10
- 230000005284 excitation Effects 0.000 description 10
- 238000013507 mapping Methods 0.000 description 10
- 238000002679 ablation Methods 0.000 description 9
- 239000000463 material Substances 0.000 description 9
- 230000006870 function Effects 0.000 description 8
- 230000005684 electric field Effects 0.000 description 7
- 239000012530 fluid Substances 0.000 description 7
- 238000010586 diagram Methods 0.000 description 6
- 230000000694 effects Effects 0.000 description 6
- 238000002955 isolation Methods 0.000 description 6
- 230000008901 benefit Effects 0.000 description 5
- 230000007246 mechanism Effects 0.000 description 5
- 238000006243 chemical reaction Methods 0.000 description 4
- 239000004020 conductor Substances 0.000 description 4
- 238000011156 evaluation Methods 0.000 description 4
- 230000003187 abdominal effect Effects 0.000 description 3
- 239000008280 blood Substances 0.000 description 3
- 210000004369 blood Anatomy 0.000 description 3
- 238000004364 calculation method Methods 0.000 description 3
- 230000000747 cardiac effect Effects 0.000 description 3
- 230000008878 coupling Effects 0.000 description 3
- 238000010168 coupling process Methods 0.000 description 3
- 238000005859 coupling reaction Methods 0.000 description 3
- 230000007423 decrease Effects 0.000 description 2
- 230000003247 decreasing effect Effects 0.000 description 2
- 238000000605 extraction Methods 0.000 description 2
- 230000014509 gene expression Effects 0.000 description 2
- 239000000523 sample Substances 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 238000003860 storage Methods 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 102100026816 DNA-dependent metalloprotease SPRTN Human genes 0.000 description 1
- 101710175461 DNA-dependent metalloprotease SPRTN Proteins 0.000 description 1
- 230000002776 aggregation Effects 0.000 description 1
- 238000004220 aggregation Methods 0.000 description 1
- 210000003484 anatomy Anatomy 0.000 description 1
- 238000010009 beating Methods 0.000 description 1
- 230000006399 behavior Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000003990 capacitor Substances 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 238000005352 clarification Methods 0.000 description 1
- 230000008094 contradictory effect Effects 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 238000002405 diagnostic procedure Methods 0.000 description 1
- 230000003292 diminished effect Effects 0.000 description 1
- 230000009977 dual effect Effects 0.000 description 1
- 230000005484 gravity Effects 0.000 description 1
- 230000002452 interceptive effect Effects 0.000 description 1
- 230000002262 irrigation Effects 0.000 description 1
- 238000003973 irrigation Methods 0.000 description 1
- 210000004072 lung Anatomy 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000008447 perception Effects 0.000 description 1
- 239000002504 physiological saline solution Substances 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 210000005166 vasculature Anatomy 0.000 description 1
- 238000012800 visualization Methods 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/06—Devices, other than using radiation, for detecting or locating foreign bodies ; determining position of probes within or on the body of the patient
- A61B5/061—Determining position of a probe within the body employing means separate from the probe, e.g. sensing internal probe position employing impedance electrodes on the surface of the body
- A61B5/063—Determining position of a probe within the body employing means separate from the probe, e.g. sensing internal probe position employing impedance electrodes on the surface of the body using impedance measurements
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
- A61B5/6847—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
- A61B5/6852—Catheters
- A61B5/6856—Catheters with a distal loop
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
- A61B18/14—Probes or electrodes therefor
- A61B18/1492—Probes or electrodes therefor having a flexible, catheter-like structure, e.g. for heart ablation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B34/00—Computer-aided surgery; Manipulators or robots specially adapted for use in surgery
- A61B34/20—Surgical navigation systems; Devices for tracking or guiding surgical instruments, e.g. for frameless stereotaxis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
- A61B5/053—Measuring electrical impedance or conductance of a portion of the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
- A61B5/053—Measuring electrical impedance or conductance of a portion of the body
- A61B5/0538—Measuring electrical impedance or conductance of a portion of the body invasively, e.g. using a catheter
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
- A61B5/25—Bioelectric electrodes therefor
- A61B5/279—Bioelectric electrodes therefor specially adapted for particular uses
- A61B5/28—Bioelectric electrodes therefor specially adapted for particular uses for electrocardiography [ECG]
- A61B5/282—Holders for multiple electrodes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6846—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive
- A61B5/6847—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be brought in contact with an internal body part, i.e. invasive mounted on an invasive device
- A61B5/6852—Catheters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
- A61B5/7225—Details of analog processing, e.g. isolation amplifier, gain or sensitivity adjustment, filtering, baseline or drift compensation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00053—Mechanical features of the instrument of device
- A61B2018/0016—Energy applicators arranged in a two- or three dimensional array
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00053—Mechanical features of the instrument of device
- A61B2018/00214—Expandable means emitting energy, e.g. by elements carried thereon
- A61B2018/00267—Expandable means emitting energy, e.g. by elements carried thereon having a basket shaped structure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00315—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
- A61B2018/00345—Vascular system
- A61B2018/00351—Heart
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00571—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for achieving a particular surgical effect
- A61B2018/00577—Ablation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00636—Sensing and controlling the application of energy
- A61B2018/00773—Sensed parameters
- A61B2018/00839—Bioelectrical parameters, e.g. ECG, EEG
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00636—Sensing and controlling the application of energy
- A61B2018/00773—Sensed parameters
- A61B2018/00845—Frequency
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00636—Sensing and controlling the application of energy
- A61B2018/00773—Sensed parameters
- A61B2018/00875—Resistance or impedance
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00636—Sensing and controlling the application of energy
- A61B2018/00773—Sensed parameters
- A61B2018/00892—Voltage
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
- A61B18/1206—Generators therefor
- A61B2018/128—Generators therefor generating two or more frequencies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
- A61B18/14—Probes or electrodes therefor
- A61B2018/1405—Electrodes having a specific shape
- A61B2018/1435—Spiral
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B34/00—Computer-aided surgery; Manipulators or robots specially adapted for use in surgery
- A61B34/20—Surgical navigation systems; Devices for tracking or guiding surgical instruments, e.g. for frameless stereotaxis
- A61B2034/2046—Tracking techniques
- A61B2034/2051—Electromagnetic tracking systems
- A61B2034/2053—Tracking an applied voltage gradient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
- A61B2562/02—Details of sensors specially adapted for in-vivo measurements
- A61B2562/0209—Special features of electrodes classified in A61B5/24, A61B5/25, A61B5/283, A61B5/291, A61B5/296, A61B5/053
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/06—Devices, other than using radiation, for detecting or locating foreign bodies ; determining position of probes within or on the body of the patient
- A61B5/065—Determining position of the probe employing exclusively positioning means located on or in the probe, e.g. using position sensors arranged on the probe
- A61B5/068—Determining position of the probe employing exclusively positioning means located on or in the probe, e.g. using position sensors arranged on the probe using impedance sensors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
- A61B5/7221—Determining signal validity, reliability or quality
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Surgery (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Pathology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Signal Processing (AREA)
- Cardiology (AREA)
- Radiology & Medical Imaging (AREA)
- Physiology (AREA)
- Power Engineering (AREA)
- Otolaryngology (AREA)
- Artificial Intelligence (AREA)
- Computer Vision & Pattern Recognition (AREA)
- Plasma & Fusion (AREA)
- Psychiatry (AREA)
- Robotics (AREA)
- Human Computer Interaction (AREA)
- Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
- Surgical Instruments (AREA)
- Measurement Of Resistance Or Impedance (AREA)
Abstract
Description
本出願は2017年10月24日に出願された米国仮出願第62/576,447号の優先権を主張するものであり、その内容はその全体が参考として本明細書に組み込まれる。
Claims (23)
- 接続された医療デバイスの電極の間のインピーダンスを測定するための電子制御装置であって、
コントローラであって、
共通ベース周波数の高調波である固有変調周波数をそれぞれ有している複数の駆動信号を生成し、
前記複数の駆動信号のそれぞれを、前記医療デバイスの個々の電極対間に同時に印加するように構成されている、コントローラと、
前記医療デバイスの複数の個々の電極対に印加される前記複数の駆動信号の合成応答信号を測定するための測定回路と、
復調器であって、
前記固有変調周波数ごとに、前記合成応答信号を同期復調するように構成されており、
前記固有変調周波数ごとに、当該固有変調周波数と同一の周波数と、当該固有変調周波数の位相からオフセットした既知の位相と、を有している変調信号を、前記合成応答信号に乗算する、復調器と、を備えており、
前記コントローラは、前記合成応答信号の前記同期復調に基づいて、前記電極のそれぞれのインピーダンス値を出力する、電子制御装置。 - 前記インピーダンス値は、レジスタンス(resistive)・インピーダンスおよびリアクタンス(reactive)・インピーダンスを有する複素インピーダンス値を含む、請求項1に記載の電子制御装置。
- 前記復調器は、前記共通ベース周波数に対して、整数回のサイクルを有するサンプリング期間にわたってサンプリングを行う、請求項1に記載の電子制御装置。
- 前記コントローラは、前記複数の駆動信号が前記複数の個々の電極対に印加される前に、前記複数の駆動信号を複数のデジタル駆動信号から複数のアナログ駆動信号に変換するための少なくとも1つのデジタル-アナログ変換器(DAC)をさらに備えている、請求項1に記載の電子制御装置。
- 前記複数のデジタル駆動信号を生成するための少なくとも1つの第1の数値制御発振器(NCO)をさらに備え、
前記複数のデジタル駆動信号は、前記少なくとも1つのDACによって受信される、請求項4に記載の電子制御装置。 - 前記復調器は、複数の復調信号を生成するための少なくとも1つの第2の数値制御発振器(NCO)をさらに備える、請求項5に記載の電子制御装置。
- 前記コントローラと、前記第1のNCOと、前記第2のNCOと、前記復調器は、共通のフィールドプログラマブルゲートアレイ(FPGA)の要素である、請求項5に記載の電子制御装置。
- 前記コントローラは、前記第1のNCOおよび前記第2のNCOに、前記固有変調周波数のそれぞれを入力するようにさらに構成されている、請求項6に記載の電子制御装置。
- 前記コントローラは、前記固有変調周波数ごとに、前記第1のNCOおよび前記第2のNCOに、所定のランダムな位相オフセットを入力するようにさらに構成されている、請求項8に記載の電子制御装置。
- 前記コントローラは、
前記医療デバイスの個々の電極対の数を特定し、
前記個々の電極対の数に基づいて、前記複数の駆動信号の電流レベルを調整するようにさらに構成されている、請求項1に記載の電子制御装置。 - 前記コントローラは、前記個々の電極対の数の2乗平均平方根に前記電流レベルを乗じた値に応じて、前記複数の駆動信号の合成電流レベルを所定の電流しきい値未満に維持する、請求項10に記載の電子制御装置。
- 前記コントローラは、前記個々の電極対のうちの1つまたは複数を選択的に無効にするように構成されている、請求項10に記載の電子制御装置。
- 前記コントローラは、少なくとも50個の前記駆動信号を生成するように構成されており、
前記少なくとも50個の駆動信号のそれぞれが、前記固有変調周波数と、20マイクロアンペア未満の駆動電流と、を有している、請求項1に記載の電子制御装置。 - 接続された医療デバイスの電極の間のインピーダンスを測定するための電子制御装置であって、
共通ベース周波数の高調波である固有変調周波数をそれぞれ有している複数のデジタル駆動信号を生成するように構成されている周波数ソースと、
前記複数のデジタル駆動信号を受信し、複数のアナログ駆動信号を出力するように構成されている少なくとも1つの第1のデジタル-アナログ変換器であって、
前記複数のアナログ駆動信号は、前記医療デバイスの対応する複数の個々の電極対間に同時に印加される、デジタル-アナログ変換器と、
複数の前記電極から複数のアナログ応答を受信し、前記個々の電極対に同時に印加される前記複数の駆動信号の合成デジタル応答信号を生成するように構成されている、少なくとも1つの第1のアナログ-デジタル変換器と、
前記固有変調周波数ごとに、前記合成応答信号を同期復調し、前記複数の電極に対するインピーダンス値を出力するように構成されている復調回路と、を備えている、電子制御装置。 - 前記周波数ソースは、前記複数の駆動信号を生成するための少なくとも1つの第1の数値制御発振器(NCO)をさらに含む、請求項14に記載の電子制御装置。
- 前記復調回路は、複数の復調信号を生成するための少なくとも1つの第2の数値制御発振器(NCO)をさらに備え、
前記復調信号のそれぞれは、
前記複数の駆動信号のうち対応する1つ駆動信号の前記固有変調周波数と同一の周波数と、
当該固有変調周波数の位相からオフセットした既知の位相と、を有している、請求項15に記載の電子制御装置。 - 前記第1のNCOと前記第2のNCOは、共通のフィールドプログラマブルゲートアレイ(FPGA)の要素である、請求項16に記載の電子制御装置。
- 前記周波数ソースは、少なくとも50個の前記デジタル駆動信号を生成するように構成されており、
前記少なくとも50個のデジタル駆動信号それぞれが、前記固有変調周波数と、20マイクロアンペア未満の駆動電流と、を有している、請求項14に記載の電子制御装置。 - 医療デバイスの複数の個々の電極対の間のインピーダンスを測定するために使用する方法であって、
共通ベース周波数の高調波である固有変調周波数をそれぞれ有する複数の駆動信号を生成することと、
前記複数の駆動信号のそれぞれを、前記医療デバイスの個々の電極対間に同時に印加することと、
前記医療デバイスの複数の個々の電極対間に印加される前記複数の駆動信号の合成応答信号を測定することと、
前記固有変調周波数ごとに、前記合成応答信号を同期復調することと、
前記電極のそれぞれに対して、インピーダンス値を出力することと、を備えている、方法。 - 前記同期復調することは、前記共通ベース周波数に対して、整数回のサイクルを有する期間にわたって前記合成応答信号をサンプリングすることをさらに含んでいる、請求項19に記載の方法。
- 前記医療デバイスの個々の電極対の数を特定することと、
前記個々の電極対の数に基づいて、前記複数の駆動信号の電流値を調整することと、をさらに備えている、請求項19に記載の方法。 - 前記個々の電極対の数の2乗平均平方根に電流レベルを乗じた値に応じて、前記複数の駆動信号の電流レベルの合計を所定の電流しきい値未満に維持することをさらに備えている、請求項19に記載の方法。
- 前記複数の駆動信号を生成することは、少なくとも50個の駆動信号を生成することを含んでおり、
前記少なくとも50個の駆動信号のそれぞれが、20マイクロアンペア未満の駆動電流を有している、請求項19に記載の手法。
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201762576447P | 2017-10-24 | 2017-10-24 | |
US62/576,447 | 2017-10-24 | ||
PCT/US2018/057100 WO2019083999A1 (en) | 2017-10-24 | 2018-10-23 | SYSTEM FOR MEASURING IMPEDANCE BETWEEN A PLURALITY OF ELECTRODES OF A MEDICAL DEVICE |
JP2020522839A JP7025541B2 (ja) | 2017-10-24 | 2018-10-23 | 医療デバイスの複数の電極間のインピーダンスを測定するためのシステム |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2020522839A Division JP7025541B2 (ja) | 2017-10-24 | 2018-10-23 | 医療デバイスの複数の電極間のインピーダンスを測定するためのシステム |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2022070954A true JP2022070954A (ja) | 2022-05-13 |
JP7432632B2 JP7432632B2 (ja) | 2024-02-16 |
Family
ID=64557111
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2020522839A Active JP7025541B2 (ja) | 2017-10-24 | 2018-10-23 | 医療デバイスの複数の電極間のインピーダンスを測定するためのシステム |
JP2022019596A Active JP7432632B2 (ja) | 2017-10-24 | 2022-02-10 | 医療デバイスの複数の電極間のインピーダンスを測定するためのシステム |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2020522839A Active JP7025541B2 (ja) | 2017-10-24 | 2018-10-23 | 医療デバイスの複数の電極間のインピーダンスを測定するためのシステム |
Country Status (5)
Country | Link |
---|---|
US (3) | US10750974B2 (ja) |
EP (2) | EP3881788B1 (ja) |
JP (2) | JP7025541B2 (ja) |
CN (1) | CN111246816B (ja) |
WO (1) | WO2019083999A1 (ja) |
Families Citing this family (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8449599B2 (en) | 2009-12-04 | 2013-05-28 | Edwards Lifesciences Corporation | Prosthetic valve for replacing mitral valve |
EP2961351B1 (en) | 2013-02-26 | 2018-11-28 | Mitralign, Inc. | Devices for percutaneous tricuspid valve repair |
WO2015059699A2 (en) | 2013-10-23 | 2015-04-30 | Valtech Cardio, Ltd. | Anchor magazine |
WO2016090308A1 (en) | 2014-12-04 | 2016-06-09 | Edwards Lifesciences Corporation | Percutaneous clip for repairing a heart valve |
WO2016183485A1 (en) | 2015-05-14 | 2016-11-17 | Edwards Lifesciences Corporation | Heart valve sealing devices and delivery devices therefor |
US10799675B2 (en) | 2016-03-21 | 2020-10-13 | Edwards Lifesciences Corporation | Cam controlled multi-direction steerable handles |
US10905554B2 (en) | 2017-01-05 | 2021-02-02 | Edwards Lifesciences Corporation | Heart valve coaptation device |
US10675017B2 (en) | 2017-02-07 | 2020-06-09 | Edwards Lifesciences Corporation | Transcatheter heart valve leaflet plication |
MX2019010326A (es) | 2017-04-18 | 2019-10-21 | Edwards Lifesciences Corp | Dispositivos de sellado de valvula cardiaca y dispositivos de suministro para los mismos. |
US11224511B2 (en) | 2017-04-18 | 2022-01-18 | Edwards Lifesciences Corporation | Heart valve sealing devices and delivery devices therefor |
US11051940B2 (en) | 2017-09-07 | 2021-07-06 | Edwards Lifesciences Corporation | Prosthetic spacer device for heart valve |
US11040174B2 (en) | 2017-09-19 | 2021-06-22 | Edwards Lifesciences Corporation | Multi-direction steerable handles for steering catheters |
CA3086678A1 (en) | 2018-01-09 | 2019-07-18 | Edwards Lifesciences Corporation | Native valve repair devices and procedures |
US10231837B1 (en) | 2018-01-09 | 2019-03-19 | Edwards Lifesciences Corporation | Native valve repair devices and procedures |
WO2019215721A1 (en) * | 2018-05-06 | 2019-11-14 | Navix International Limited | Measuring electrical impedance, contact force, and tissue properties |
US10945844B2 (en) | 2018-10-10 | 2021-03-16 | Edwards Lifesciences Corporation | Heart valve sealing devices and delivery devices therefor |
BR122021018592A2 (pt) | 2019-02-14 | 2021-10-13 | Edwards Lifesciences Corporation | Fecho de dispositivo de reparo de válvula para reparar uma válvula nativa de um paciente |
US20200383599A1 (en) * | 2019-06-07 | 2020-12-10 | Lake Region Manufacturing, Inc. | Basket-type ep catheter with electrode polling for sequential electrode sampling |
WO2021011685A1 (en) * | 2019-07-18 | 2021-01-21 | St. Jude Medical, Cardiology Division, Inc. | System and method for noise tolerant cardiac localization, navigation and mapping |
US20230190364A1 (en) | 2020-05-20 | 2023-06-22 | St. Jude Medical, Cardiology Division, Inc. | Systems and methods for monitoring return patch impedances |
US20220233230A1 (en) * | 2021-01-27 | 2022-07-28 | NovaScan, Inc. | Impedance-calibrated diagnostic medical devices |
CN113995501A (zh) | 2021-05-25 | 2022-02-01 | 圣犹达医疗用品心脏病学部门有限公司 | 用于配设有网篮和球囊的电穿孔设备的系统和方法 |
WO2022266043A1 (en) | 2021-06-14 | 2022-12-22 | St. Jude Medical, Cardiology Division, Inc. | Systems and methods for isolating wires in electroporation devices |
US20230052114A1 (en) | 2021-08-12 | 2023-02-16 | St. Jude Medical, Cardiology Division, Inc. | Systems and methods for electroporation using asymmetric waveforms and waveforms with reduced burst duration |
CN114305380A (zh) * | 2021-12-02 | 2022-04-12 | 四川锦江电子科技有限公司 | 阻抗网络检测装置与方法 |
US20230240745A1 (en) | 2022-01-28 | 2023-08-03 | St. Jude Medical, Cardiology Division, Inc. | Systems and methods for electroporation using waveforms that reduce electrical stimulation |
US20230329769A1 (en) | 2022-04-19 | 2023-10-19 | St. Jude Medical, Cardiology Division, Inc. | Systems and methods for electroporation using arbitrary electrode addressing |
WO2024086033A1 (en) | 2022-10-17 | 2024-04-25 | St. Jude Medical, Cardiology Division, Inc. | Systems and methods for monitoring pulsed field ablation generator output |
US20240164834A1 (en) | 2022-11-18 | 2024-05-23 | St. Jude Medical, Cardiology Division, Inc. | Systems and methods for catheters having combined mapping and ablation capabilities |
US11931095B1 (en) | 2023-01-12 | 2024-03-19 | St. Jude Medical, Cardiology Division, Inc. | Method and system for determining baseline electrode impedance for tissue contact detection |
US11950833B1 (en) | 2023-01-12 | 2024-04-09 | St. Jude Medical, Cardiology Division, Inc. | Method and system for detecting contact status using electrode |
US11969261B1 (en) | 2023-01-12 | 2024-04-30 | St. Jude Medical, Cardiology Division, Inc. | Method and system for modifying contact status of an electrode |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2006501903A (ja) * | 2002-10-09 | 2006-01-19 | クイーンスランド ユニバーシティー オブ テクノロジー | 高分解能生体インピーダンス装置 |
WO2016081786A1 (en) * | 2014-11-19 | 2016-05-26 | Stereotaxis, Inc. | Inter-electrode impedance for detecting tissue distance, orientation, contact and contact quality |
JP2016524480A (ja) * | 2013-06-11 | 2016-08-18 | セント・ジュード・メディカル・エイトリアル・フィブリレーション・ディヴィジョン・インコーポレーテッド | マルチ電極インピーダンス・センシング |
WO2016153561A1 (en) * | 2015-03-25 | 2016-09-29 | Advanced Cardiac Therapeutics, Inc. | Contact sensing systems and methods |
JP2016187720A (ja) * | 2010-11-08 | 2016-11-04 | バイオセンス・ウエブスター・(イスラエル)・リミテッドBiosense Webster (Israel), Ltd. | 複数電極による同時アブレーション |
Family Cites Families (49)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4587975A (en) | 1984-07-02 | 1986-05-13 | Cardiac Pacemakers, Inc. | Dimension sensitive angioplasty catheter |
US5341807A (en) | 1992-06-30 | 1994-08-30 | American Cardiac Ablation Co., Inc. | Ablation catheter positioning system |
SE9300825D0 (sv) | 1993-03-12 | 1993-03-12 | Siemens Elema Ab | Anordning foer maetning av elektrisk aktivitet i hjaertat |
US5836990A (en) | 1997-09-19 | 1998-11-17 | Medtronic, Inc. | Method and apparatus for determining electrode/tissue contact |
US6129669A (en) | 1998-05-22 | 2000-10-10 | Scimed Life Systems, Inc. | Systems and methods for assessing stability of an ablation electrode in contact with heart tissue |
US7263397B2 (en) | 1998-06-30 | 2007-08-28 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Method and apparatus for catheter navigation and location and mapping in the heart |
US6391024B1 (en) | 1999-06-17 | 2002-05-21 | Cardiac Pacemakers, Inc. | RF ablation apparatus and method having electrode/tissue contact assessment scheme and electrocardiogram filtering |
US6471693B1 (en) * | 1999-09-10 | 2002-10-29 | Cryocath Technologies Inc. | Catheter and system for monitoring tissue contact |
US6569160B1 (en) | 2000-07-07 | 2003-05-27 | Biosense, Inc. | System and method for detecting electrode-tissue contact |
US6546270B1 (en) | 2000-07-07 | 2003-04-08 | Biosense, Inc. | Multi-electrode catheter, system and method |
US8905937B2 (en) | 2009-02-26 | 2014-12-09 | Integrated Vascular Systems, Inc. | Methods and apparatus for locating a surface of a body lumen |
CA2516559C (en) | 2003-02-21 | 2016-09-27 | Electro-Cat, Llc | System and method for measuring cross-sectional areas and pressure gradients in luminal organs |
US9277955B2 (en) * | 2010-04-09 | 2016-03-08 | Vessix Vascular, Inc. | Power generating and control apparatus for the treatment of tissue |
EP1754441B1 (en) * | 2005-08-17 | 2008-01-09 | Osypka Medical GmbH | Method and apparatus for digital demodulation in the measurement of electrical bioimpedance or bioadmittance |
US7885707B2 (en) | 2005-09-15 | 2011-02-08 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Method of scaling navigation signals to account for impedance drift in tissue |
US8672936B2 (en) | 2005-10-13 | 2014-03-18 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Systems and methods for assessing tissue contact |
US8162935B2 (en) | 2005-10-27 | 2012-04-24 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Systems and methods for electrode contact assessment |
US8696656B2 (en) | 2005-11-18 | 2014-04-15 | Medtronic Cryocath Lp | System and method for monitoring bioimpedance and respiration |
US8403925B2 (en) | 2006-12-06 | 2013-03-26 | St. Jude Medical, Atrial Fibrillation Division, Inc. | System and method for assessing lesions in tissue |
CA2631940C (en) | 2005-12-06 | 2016-06-21 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Assessment of electrode coupling for tissue ablation |
US8406866B2 (en) | 2005-12-06 | 2013-03-26 | St. Jude Medical, Atrial Fibrillation Division, Inc. | System and method for assessing coupling between an electrode and tissue |
US9788750B2 (en) * | 2007-04-30 | 2017-10-17 | Medtronic, Inc. | Seizure prediction |
US8160690B2 (en) | 2007-06-14 | 2012-04-17 | Hansen Medical, Inc. | System and method for determining electrode-tissue contact based on amplitude modulation of sensed signal |
US8211102B2 (en) | 2007-12-21 | 2012-07-03 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Contact sensing flexible conductive polymer electrode |
US20100010612A1 (en) | 2008-07-09 | 2010-01-14 | Daniel Gelbart | Lumen diameter and stent apposition sensing |
JP5649573B2 (ja) | 2008-08-22 | 2015-01-07 | コーニンクレッカ フィリップス エヌ ヴェ | 対象物を検知するための検知装置 |
US8700129B2 (en) | 2008-12-31 | 2014-04-15 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Devices and methods for catheter localization |
US8556850B2 (en) | 2008-12-31 | 2013-10-15 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Shaft and handle for a catheter with independently-deflectable segments |
JP5755234B2 (ja) * | 2009-11-18 | 2015-07-29 | インぺディメッド リミテッドImpedimed Limited | 患者−電極間測定のための装置およびシステム |
CN102939051A (zh) | 2010-06-13 | 2013-02-20 | 安吉奥梅特里克斯公司 | 用于确定血管体腔的信息并引导医疗设备的方法和系统 |
EP2433564A1 (de) | 2010-09-23 | 2012-03-28 | BIOTRONIK SE & Co. KG | Positionierung von Kathetern mittels Impedanzmessung |
US9005193B2 (en) * | 2010-11-08 | 2015-04-14 | Biosense Webster (Israel) Ltd. | Multichannel ablation with frequency differentiation |
US9113807B2 (en) | 2010-12-29 | 2015-08-25 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Dynamic adaptive respiration compensation with automatic gain control |
US9687289B2 (en) | 2012-01-04 | 2017-06-27 | Biosense Webster (Israel) Ltd. | Contact assessment based on phase measurement |
CN104582619B (zh) | 2012-04-26 | 2018-12-04 | 麦德托尼克消融前沿有限公司 | 用于检测消融期间组织接触的系统 |
US20130296840A1 (en) | 2012-05-01 | 2013-11-07 | Medtronic Ablation Frontiers Llc | Systems and methods for detecting tissue contact during ablation |
US9213010B2 (en) * | 2012-06-08 | 2015-12-15 | Medtronic Minimed, Inc. | Application of electrochemical impedance spectroscopy in sensor systems, devices, and related methods |
US9498275B2 (en) * | 2013-03-14 | 2016-11-22 | Covidien Lp | Systems and methods for arc detection and drag adjustment |
US20150157240A1 (en) * | 2013-12-06 | 2015-06-11 | General Electric Company | Electrical impedance imaging systems |
EP3082575A2 (en) * | 2013-12-19 | 2016-10-26 | Cardiac Pacemakers, Inc. | System and method for locating neural tissue |
US9901385B2 (en) * | 2014-01-13 | 2018-02-27 | Covidien Lp | Systems and methods for multifrequency cable compensation |
DE102014206311B3 (de) * | 2014-04-02 | 2015-10-08 | Siemens Aktiengesellschaft | Empfangssystem für Lokalspulen eines Magnetresonanztomographiesystems |
WO2016081650A1 (en) | 2014-11-19 | 2016-05-26 | Advanced Cardiac Therapeutics, Inc. | Ablation devices, systems and methods of using a high-resolution electrode assembly |
US10631913B2 (en) * | 2014-12-31 | 2020-04-28 | St. Jude Medical, Cardiology Division, Inc. | Filter circuit for electrophysiology system |
US20160242667A1 (en) | 2015-02-20 | 2016-08-25 | Boston Scientific Scimed Inc. | Tissue contact sensing using a medical device |
US10182742B2 (en) | 2015-04-02 | 2019-01-22 | Medtronic Ablation Frontiers Llc | Tissue contact sensing with a multi electrode ablation catheter |
JP7013023B2 (ja) * | 2015-05-21 | 2022-01-31 | イービーティー メディカル,インコーポレイテッド | 膀胱機能障害の治療のためのシステム及び方法 |
US20170007157A1 (en) * | 2015-07-08 | 2017-01-12 | Rainbow Medical Ltd. | Electrical-signal-based electrode-tissue contact detection |
US10384062B2 (en) * | 2016-11-03 | 2019-08-20 | Calmare Therapeutics Incorporated | Pain management system, method and device using analytics driven random electrical stimuli |
-
2018
- 2018-10-23 JP JP2020522839A patent/JP7025541B2/ja active Active
- 2018-10-23 US US16/168,423 patent/US10750974B2/en active Active
- 2018-10-23 EP EP21173084.1A patent/EP3881788B1/en active Active
- 2018-10-23 WO PCT/US2018/057100 patent/WO2019083999A1/en unknown
- 2018-10-23 CN CN201880067880.0A patent/CN111246816B/zh active Active
- 2018-10-23 EP EP18811388.0A patent/EP3668432B1/en active Active
-
2020
- 2020-07-16 US US16/930,905 patent/US11439319B2/en active Active
-
2022
- 2022-02-10 JP JP2022019596A patent/JP7432632B2/ja active Active
- 2022-08-10 US US17/884,758 patent/US20230077196A1/en active Pending
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2006501903A (ja) * | 2002-10-09 | 2006-01-19 | クイーンスランド ユニバーシティー オブ テクノロジー | 高分解能生体インピーダンス装置 |
JP2016187720A (ja) * | 2010-11-08 | 2016-11-04 | バイオセンス・ウエブスター・(イスラエル)・リミテッドBiosense Webster (Israel), Ltd. | 複数電極による同時アブレーション |
JP2016524480A (ja) * | 2013-06-11 | 2016-08-18 | セント・ジュード・メディカル・エイトリアル・フィブリレーション・ディヴィジョン・インコーポレーテッド | マルチ電極インピーダンス・センシング |
WO2016081786A1 (en) * | 2014-11-19 | 2016-05-26 | Stereotaxis, Inc. | Inter-electrode impedance for detecting tissue distance, orientation, contact and contact quality |
WO2016153561A1 (en) * | 2015-03-25 | 2016-09-29 | Advanced Cardiac Therapeutics, Inc. | Contact sensing systems and methods |
Also Published As
Publication number | Publication date |
---|---|
EP3881788A1 (en) | 2021-09-22 |
US10750974B2 (en) | 2020-08-25 |
CN111246816A (zh) | 2020-06-05 |
WO2019083999A1 (en) | 2019-05-02 |
JP7025541B2 (ja) | 2022-02-24 |
US20190117113A1 (en) | 2019-04-25 |
JP2021500153A (ja) | 2021-01-07 |
CN111246816B (zh) | 2023-07-14 |
EP3881788B1 (en) | 2022-11-16 |
US20230077196A1 (en) | 2023-03-09 |
US20200345264A1 (en) | 2020-11-05 |
EP3668432B1 (en) | 2021-06-16 |
EP3668432A1 (en) | 2020-06-24 |
US11439319B2 (en) | 2022-09-13 |
JP7432632B2 (ja) | 2024-02-16 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JP7025541B2 (ja) | 医療デバイスの複数の電極間のインピーダンスを測定するためのシステム | |
JP7106644B2 (ja) | 複素インピーダンス測定を用いて、電極と組織との間の接触を評価する方法 | |
EP3753479B1 (en) | Extension of electrocardiography (ecg) acquisition capabilities of catheter-based cardiac system | |
JP6234795B2 (ja) | マルチチャンネルecg測定 | |
WO2014201113A1 (en) | Multi-electrode impedance sensing | |
CA2719329A1 (en) | Intra-cardiac tracking system | |
EP1648297A2 (en) | Noninvasive multi-channel monitoring of hemodynamic parameters | |
EP3209197B1 (en) | Simultaneous impedance testing method and apparatus | |
ES2731331T3 (es) | Sistema y método para procesar señales de catéteres intracardiacos | |
EP3449816B1 (en) | Medical system comprising a patch for simultaneously sensing ecg signals and impedance-indicative electrical signals | |
US20220296309A1 (en) | System and method for noise tolerant cardiac localization, navigation and mapping | |
RU2422084C2 (ru) | Устройство слежения за электродами внутри тела пациента и способ его реализации | |
CN111214229A (zh) | 补偿跟踪体内探头期间的人工痕迹 | |
CN110623656A (zh) | 通过主动断开未使用的连接来改善多路复用系统中的信号质量 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20220310 |
|
A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20220310 |
|
A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20230110 |
|
A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20230407 |
|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20230612 |
|
A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20231003 |
|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20231222 |
|
TRDD | Decision of grant or rejection written | ||
A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20240109 |
|
A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20240205 |
|
R150 | Certificate of patent or registration of utility model |
Ref document number: 7432632 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R150 |