JP2021533913A - 脈波伝播速度測定を実行するためのシステム及び方法 - Google Patents
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Abstract
Description
パルス起点において、血管に沿って導かれる複数の血管内超音波パルスを生成するステップと、
各超音波パルスに対して、血管の中心軸に沿った複数の距離から複数のエコーを受信するステップと、
パルス起点から第1の距離からの第1の超音波ドップラ信号と、パルス起点から第2の距離からの第2の超音波ドップラ信号とを取得するステップと、
第1の超音波ドップラ信号及び第2の超音波ドップラ信号に基づいて時間遅延を計算するステップと、
時間遅延に基づいて脈波伝播速度を計算するステップと
を有する。
第1の超音波ドップラ信号に基づいて第1の流速メトリックを取得することと、
第2の超音波ドップラ信号に基づいて第2の流速メトリックを取得することと、
第1の流速メトリック及び第2の流速メトリックに基づいて時間遅延を計算することと
を含む。
流速の第1の分布及び流速の第2の分布の各速度値に対して、個々の時間遅延を計算することと、
個々の時間遅延に基づいて平均時間遅延を計算することと
を含む。
流速の第1の分布の第1の特徴を抽出することと、
流速の第2の分布の第2の特徴を抽出することと、
第1の特徴及び第2の特徴に基づいて時間遅延を計算することと
を含む。
瞬間ピーク速度、
脈拍開始、
ピーク時間、
最大加速度、及び
瞬間平均速度
のうちの1つ又は複数を含む。
血管内超音波ユニットは、
パルス起点において、血管に沿って導かれる複数の血管内超音波パルスを生成し、
各超音波パルスに対して、血管の中心軸に沿った複数の距離から複数のエコーを受信するように構成され、
プロセッサは、
パルス起点から第1の距離からの第1の超音波ドップラ信号と、パルス起点から第2の距離からの第2の超音波ドップラ信号とを取得し、
第1の超音波ドップラ信号及び第2の超音波ドップラ信号に基づいて時間遅延を計算し、
時間遅延に基づいて脈波伝播速度を計算するように構成される。
単一の超音波トランスデューサ要素、
超音波トランスデューサ要素のアレイ、又は
互いに空間的に独立している第1の血管内超音波要素及び第2の血管内超音波要素
を含む。
Δtmin≫1/fPRF
ここで、fPRFは、超音波トランスデューサのパルスレート周波数、すなわち、毎秒生成される超音波パルスの数である。
Claims (15)
- 血管内脈波伝播速度測定を実行するためのシステムであって、前記システムは、血管内超音波デバイスとプロセッサとを含み、
前記血管内超音波デバイスは、
パルス起点において、血管に沿って導かれる複数の血管内超音波パルスを生成し、
各超音波パルスに対して、前記血管に沿った複数の距離から複数のエコーを受信し、
前記プロセッサは、
前記パルス起点から第1の距離からの第1の超音波ドップラ信号と、前記パルス起点から第2の距離からの第2の超音波ドップラ信号とを取得し、
取得された前記第1及び第2の超音波ドップラ信号に基づいて、前記第1の距離における速度特性の変異が前記第2の距離に伝播するのに要する時間遅延を把握し、
前記時間遅延に基づいて前記脈波伝播速度を計算する、
システム。 - 前記血管内超音波デバイスが、単一の超音波トランスデューサ要素、又は超音波トランスデューサ要素のアレイを含む、請求項1に記載のシステム。
- 前記時間遅延を把握することが、前記第1の超音波ドップラ信号と前記第2の超音波ドップラ信号との間の相互相関を実行することを含む、請求項1又は2に記載のシステム。
- 前記時間遅延を把握することが、前記第1及び前記第2の超音波ドップラ信号に基づいて第1及び第2の流速メトリックを取得することを含む、請求項1又は2に記載のシステム。
- 前記第1の流速メトリックが第1の平均速度を含み、前記第2の流速メトリックが第2の平均速度を含む、請求項4に記載のシステム。
- 前記第1の流速メトリックが流速の第1の分布を含み、前記第2の流速メトリックが流速の第2の分布を含む、請求項4に記載のシステム。
- 前記流速の第1の分布が第1の周波数スペクトルを含み、前記流速の第2の分布が第2の周波数スペクトルを含む、請求項6に記載のシステム。
- 前記時間遅延を把握することが、
前記流速の第1の分布及び前記流速の第2の分布の各速度値に対して、個々の時間遅延を計算することと、
前記個々の時間遅延に基づいて平均時間遅延を計算することと
を含む、請求項6又は7に記載のシステム。 - 前記時間遅延を把握することが、
前記流速の第1の分布の第1の特徴を抽出することと、
前記流速の第2の分布の第2の特徴を抽出することと、
前記第1の特徴及び前記第2の特徴に基づいて時間遅延を計算することと
を含む、請求項6又は7に記載のシステム。 - 前記第1及び第2の特徴が、
瞬間ピーク速度、
脈拍開始、
ピーク時間、
最大加速度、及び
瞬間平均速度
のうちの1つ又は複数を含む、請求項9に記載のシステム。 - 前記時間遅延を把握することが、前記流速の第1の分布と前記流速の第2の分布との間の相互相関を実行することを含む、請求項6又は7に記載のシステム。
- 前記システムが、さらに、圧力メトリックを取得し、前記脈波伝播速度の計算が、前記時間遅延及び前記圧力メトリックに基づく、請求項1から11のいずれか一項に記載のシステム。
- 前記血管に沿って前記複数の血管内超音波パルスを導くことが、電子的ビームステアリング及び/又は電子的ビーム焦点合せを含む、請求項1に記載のシステム。
- 脈波伝播速度を計算する方法であって、前記方法が、
パルス起点において、血管に沿って導かれる複数の血管内超音波パルスを生成するステップと、
各超音波パルスに対して、前記血管に沿った複数の距離から複数のエコーを受信するステップと、
前記パルス起点から第1の距離からの第1の超音波ドップラ信号と、前記パルス起点から第2の距離からの第2の超音波ドップラ信号とを取得するステップと、
取得された前記第1及び第2の超音波ドップラ信号に基づいて、前記第1の距離における速度特性の変異が前記第2の距離に伝播するのに要する時間遅延を把握するステップと、
前記時間遅延に基づいて前記脈波伝播速度を計算するステップと
を有する、方法。 - コンピュータプログラムがコンピュータで実行されるとき、請求項1から13のいずれか一項に記載のシステムで請求項14に記載の方法を実施するために適合されたコンピュータプログラムコード手段を含む、コンピュータプログラム。
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EP18189871.9A EP3613350A1 (en) | 2018-08-21 | 2018-08-21 | Systems and method for performing pulse wave velocity measurements |
PCT/EP2019/071634 WO2020038757A1 (en) | 2018-08-21 | 2019-08-13 | Systems and method for performing pulse wave velocity measurements |
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CN111227867B (zh) * | 2020-03-10 | 2021-01-12 | 云南大学 | 一种超声多普勒血流成像方法及系统 |
CN115844452B (zh) * | 2022-12-26 | 2024-05-24 | 北京翌影科技有限公司 | 一种脉搏波检测方法、装置和存储介质 |
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WO2020038757A1 (en) | 2020-02-27 |
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