JP2021533166A5 - - Google Patents
Info
- Publication number
- JP2021533166A5 JP2021533166A5 JP2021506492A JP2021506492A JP2021533166A5 JP 2021533166 A5 JP2021533166 A5 JP 2021533166A5 JP 2021506492 A JP2021506492 A JP 2021506492A JP 2021506492 A JP2021506492 A JP 2021506492A JP 2021533166 A5 JP2021533166 A5 JP 2021533166A5
- Authority
- JP
- Japan
- Prior art keywords
- component
- target ligand
- car
- payload drug
- drug
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862715666P | 2018-08-07 | 2018-08-07 | |
| US62/715,666 | 2018-08-07 | ||
| PCT/US2019/042726 WO2020033129A1 (en) | 2018-08-07 | 2019-07-21 | Rejuvenation of car t cell |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021533166A JP2021533166A (ja) | 2021-12-02 |
| JP2021533166A5 true JP2021533166A5 (enExample) | 2022-07-28 |
| JP7623935B2 JP7623935B2 (ja) | 2025-01-29 |
Family
ID=69415080
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021506492A Active JP7623935B2 (ja) | 2018-08-07 | 2019-07-21 | Ｃａｒ ｔ細胞の若返り |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US20210308267A1 (enExample) |
| EP (1) | EP3833400A4 (enExample) |
| JP (1) | JP7623935B2 (enExample) |
| KR (1) | KR20210042125A (enExample) |
| CN (2) | CN116763943A (enExample) |
| AU (1) | AU2019317278B2 (enExample) |
| CA (1) | CA3108710A1 (enExample) |
| SG (1) | SG11202100616VA (enExample) |
| WO (1) | WO2020033129A1 (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2934532B1 (en) | 2012-12-20 | 2019-10-23 | Purdue Research Foundation | Chimeric antigen receptor-expressing t cells as anti-cancer therapeutics |
| CA3019835A1 (en) | 2016-04-08 | 2017-10-12 | Purdue Research Foundation | Methods and compositions for car t cell therapy |
| CN110582288B (zh) | 2017-02-28 | 2024-09-20 | 恩多塞特公司 | 用于car t细胞疗法的组合物和方法 |
| WO2019144095A1 (en) | 2018-01-22 | 2019-07-25 | Seattle Children's Hospital (dba Seattle Children's Research Institute) | Methods of use for car t cells |
| JP7568224B2 (ja) | 2018-02-23 | 2024-10-16 | エンドサイト・インコーポレイテッド | Ｃａｒ ｔ細胞療法のための配列決定法 |
| SG11202009975TA (en) | 2018-04-12 | 2020-11-27 | Umoja Biopharma Inc | Viral vectors and packaging cell lines |
| AU2019317278B2 (en) | 2018-08-07 | 2025-05-22 | Purdue Research Foundation | Rejuvenation of CAR T cell |
| IL295063A (en) | 2020-02-04 | 2022-09-01 | Seattle Childrens Hospital Dba Seattle Childrens Res Inst | Chimeric antigen receptors (car) against dinitrophenol |
| US20240058458A1 (en) * | 2020-03-06 | 2024-02-22 | Purdue Research Foundation | Methods, compounds, and compositions for modifying car-t cell activity |
| AU2021246112A1 (en) * | 2020-04-03 | 2022-11-10 | Cellvie Inc. | Enhancement of adoptive cell transfer |
| US20240293456A1 (en) * | 2020-11-30 | 2024-09-05 | Purdue Research Foundation | Combinations of small molecule drug conjugate and car-expressing cytotoxic lymphocytes and methods of treating cancer using the same |
| CN118139627A (zh) * | 2021-08-30 | 2024-06-04 | 普渡研究基金会 | 使car t细胞恢复活力的缀合物、组合物和方法 |
| WO2023156510A1 (en) * | 2022-02-18 | 2023-08-24 | F. Hoffmann-La Roche Ag | Method for detecting an analyte of interest in a sample |
Family Cites Families (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6093382A (en) | 1998-05-16 | 2000-07-25 | Bracco Research Usa Inc. | Metal complexes derivatized with folate for use in diagnostic and therapeutic applications |
| EP2371854B1 (en) | 2001-03-09 | 2014-05-07 | Board Of Regents, The University Of Texas System | Induction of tumor immunity by variants of folate binding protein |
| WO2005103250A1 (ja) | 2004-04-26 | 2005-11-03 | Takami Matsuyama | 葉酸リセプターベータ（FR-β）に対する単クローン抗体を含有する治療薬 |
| CA2695374A1 (en) * | 2007-08-15 | 2009-02-19 | Amunix, Inc. | Compositions and methods for modifying properties of biologically active polypeptides |
| WO2010118169A2 (en) | 2009-04-08 | 2010-10-14 | The Regents Of The University Of California | Human protein scaffold with controlled serum pharmacokinetics |
| US20120258905A1 (en) | 2009-12-23 | 2012-10-11 | Endocyte, Inc. | Vitamin receptor drug delivery conjugates for treating inflammation |
| EP2934532B1 (en) | 2012-12-20 | 2019-10-23 | Purdue Research Foundation | Chimeric antigen receptor-expressing t cells as anti-cancer therapeutics |
| AU2014337385B2 (en) * | 2013-10-15 | 2020-04-30 | The Scripps Research Institute | Chimeric antigen receptor T cell switches and uses thereof |
| AU2014337367B2 (en) * | 2013-10-15 | 2020-04-30 | The Scripps Research Institute | Peptidic chimeric antigen receptor T cell switches and uses thereof |
| ES2918501T3 (es) * | 2013-12-19 | 2022-07-18 | Novartis Ag | Receptores de antígenos quiméricos de mesotelina humana y usos de los mismos |
| WO2015092024A2 (en) * | 2013-12-20 | 2015-06-25 | Cellectis | Method of engineering multi-input signal sensitive t cell for immunotherapy |
| CN122399016A (zh) * | 2014-03-15 | 2026-07-17 | 诺华股份有限公司 | 使用嵌合抗原受体治疗癌症 |
| US20170158749A1 (en) | 2014-04-23 | 2017-06-08 | Board Of Regents, The University Of Texas System | Chimeric antigen receptors (car) and methods for making and using the same |
| WO2016098078A2 (en) | 2014-12-19 | 2016-06-23 | Novartis Ag | Dimerization switches and uses thereof |
| US10683506B2 (en) | 2015-04-10 | 2020-06-16 | The Methodist Hospital System | CD117 ligand-drug conjugates for targeted cancer therapy |
| WO2017035117A1 (en) * | 2015-08-24 | 2017-03-02 | University Of Houston System | Combination therpay combining car + t cells with appropriately timed immunodulatory antibodies |
| AU2017248259A1 (en) * | 2016-04-07 | 2018-10-25 | Bluebird Bio, Inc. | Chimeric antigen receptor T cell compositions |
| CA3019835A1 (en) * | 2016-04-08 | 2017-10-12 | Purdue Research Foundation | Methods and compositions for car t cell therapy |
| CN109475558A (zh) * | 2016-05-25 | 2019-03-15 | 普渡研究基金会 | 通过靶向骨髓衍生的抑制细胞而治疗癌症的方法 |
| JP7162592B2 (ja) * | 2016-12-14 | 2022-10-28 | パーデュー・リサーチ・ファウンデイション | 線維芽細胞活性化タンパク質（ｆａｐ）標的イメージングおよび治療 |
| ES3024357T3 (en) * | 2017-02-17 | 2025-06-04 | Purdue Research Foundation | Targeted ligand-payload based drug delivery for cell therapy |
| CN110582288B (zh) | 2017-02-28 | 2024-09-20 | 恩多塞特公司 | 用于car t细胞疗法的组合物和方法 |
| WO2019144095A1 (en) | 2018-01-22 | 2019-07-25 | Seattle Children's Hospital (dba Seattle Children's Research Institute) | Methods of use for car t cells |
| JP7568224B2 (ja) | 2018-02-23 | 2024-10-16 | エンドサイト・インコーポレイテッド | Ｃａｒ ｔ細胞療法のための配列決定法 |
| AU2019317278B2 (en) | 2018-08-07 | 2025-05-22 | Purdue Research Foundation | Rejuvenation of CAR T cell |
| US20240058458A1 (en) | 2020-03-06 | 2024-02-22 | Purdue Research Foundation | Methods, compounds, and compositions for modifying car-t cell activity |
| CN120390641A (zh) | 2022-10-19 | 2025-07-29 | 西雅图儿童医院（Dba西雅图儿童研究所） | 采用靶向小分子和抗靶向car t细胞的治疗方法 |
-
2019
- 2019-07-21 AU AU2019317278A patent/AU2019317278B2/en active Active
- 2019-07-21 CN CN202310525133.XA patent/CN116763943A/zh active Pending
- 2019-07-21 EP EP19847190.6A patent/EP3833400A4/en active Pending
- 2019-07-21 CA CA3108710A patent/CA3108710A1/en active Pending
- 2019-07-21 JP JP2021506492A patent/JP7623935B2/ja active Active
- 2019-07-21 SG SG11202100616VA patent/SG11202100616VA/en unknown
- 2019-07-21 US US17/266,509 patent/US20210308267A1/en not_active Abandoned
- 2019-07-21 WO PCT/US2019/042726 patent/WO2020033129A1/en not_active Ceased
- 2019-07-21 CN CN201980052586.7A patent/CN112543651B/zh active Active
- 2019-07-21 KR KR1020217006445A patent/KR20210042125A/ko not_active Ceased
-
2023
- 2023-12-21 US US18/392,939 patent/US12622973B2/en active Active
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