JP2021533166A5 - - Google Patents

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Publication number
JP2021533166A5
JP2021533166A5 JP2021506492A JP2021506492A JP2021533166A5 JP 2021533166 A5 JP2021533166 A5 JP 2021533166A5 JP 2021506492 A JP2021506492 A JP 2021506492A JP 2021506492 A JP2021506492 A JP 2021506492A JP 2021533166 A5 JP2021533166 A5 JP 2021533166A5
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JP
Japan
Prior art keywords
component
target ligand
car
payload drug
drug
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2021506492A
Other languages
English (en)
Japanese (ja)
Other versions
JP7623935B2 (ja
JP2021533166A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2019/042726 external-priority patent/WO2020033129A1/en
Publication of JP2021533166A publication Critical patent/JP2021533166A/ja
Publication of JP2021533166A5 publication Critical patent/JP2021533166A5/ja
Application granted granted Critical
Publication of JP7623935B2 publication Critical patent/JP7623935B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2021506492A 2018-08-07 2019-07-21 Car t細胞の若返り Active JP7623935B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862715666P 2018-08-07 2018-08-07
US62/715,666 2018-08-07
PCT/US2019/042726 WO2020033129A1 (en) 2018-08-07 2019-07-21 Rejuvenation of car t cell

Publications (3)

Publication Number Publication Date
JP2021533166A JP2021533166A (ja) 2021-12-02
JP2021533166A5 true JP2021533166A5 (enExample) 2022-07-28
JP7623935B2 JP7623935B2 (ja) 2025-01-29

Family

ID=69415080

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021506492A Active JP7623935B2 (ja) 2018-08-07 2019-07-21 Car t細胞の若返り

Country Status (9)

Country Link
US (2) US20210308267A1 (enExample)
EP (1) EP3833400A4 (enExample)
JP (1) JP7623935B2 (enExample)
KR (1) KR20210042125A (enExample)
CN (2) CN112543651B (enExample)
AU (1) AU2019317278B2 (enExample)
CA (1) CA3108710A1 (enExample)
SG (1) SG11202100616VA (enExample)
WO (1) WO2020033129A1 (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4282419A1 (en) 2012-12-20 2023-11-29 Purdue Research Foundation Chimeric antigen receptor-expressing t cells as anti-cancer therapeutics
EP3439675A4 (en) 2016-04-08 2019-12-18 Purdue Research Foundation METHOD AND COMPOSITIONS FOR CAR-T CELL THERAPY
WO2018160622A1 (en) 2017-02-28 2018-09-07 Endocyte, Inc. Compositions and methods for car t cell therapy
US11311576B2 (en) 2018-01-22 2022-04-26 Seattle Children's Hospital Methods of use for CAR T cells
AU2019225174B2 (en) 2018-02-23 2025-11-20 Endocyte, Inc. Sequencing method for CAR T cell therapy
CA3096458A1 (en) 2018-04-12 2019-10-17 Umoja Biopharma, Inc. Viral vectors and packaging cell lines
CN115210252A (zh) 2020-02-04 2022-10-18 西雅图儿童医院(Dba西雅图儿童研究所) 抗二硝基苯酚的嵌合抗原受体
AU2021231887A1 (en) * 2020-03-06 2022-10-20 Purdue Research Foundation Methods, compounds, and compositions for modifying CAR-T cell activity
CN116096861A (zh) * 2020-04-03 2023-05-09 赛立维公司 过继性细胞转移的增强
AU2021386252A1 (en) * 2020-11-30 2023-06-29 Purdue Research Foundation Combinations of small molecule drug conjugate and car-expressing cytotoxic lymphocytes and methods of treating cancer using the same
CN118139627A (zh) * 2021-08-30 2024-06-04 普渡研究基金会 使car t细胞恢复活力的缀合物、组合物和方法
JP2025506652A (ja) * 2022-02-18 2025-03-13 エフ. ホフマン-ラ ロシュ アーゲー 試料中の目的の分析物を検出するための方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010536341A (ja) * 2007-08-15 2010-12-02 アムニクス, インコーポレイテッド 生物学的に活性なポリペプチドの特性を改変するための組成物および方法
CN105829349B (zh) * 2013-10-15 2023-02-03 斯克利普斯研究所 肽嵌合抗原受体t细胞开关和其用途
CN105814083A (zh) * 2013-10-15 2016-07-27 加州生物医学研究所 嵌合抗原受体t细胞开关和其用途
ES2918501T3 (es) * 2013-12-19 2022-07-18 Novartis Ag Receptores de antígenos quiméricos de mesotelina humana y usos de los mismos
WO2015092024A2 (en) * 2013-12-20 2015-06-25 Cellectis Method of engineering multi-input signal sensitive t cell for immunotherapy
US20170335281A1 (en) * 2014-03-15 2017-11-23 Novartis Ag Treatment of cancer using chimeric antigen receptor
CA2945388A1 (en) * 2014-04-23 2015-10-29 Board Of Regents, The University Of Texas System Chimeric antigen receptors (car) for use in therapy and methods for making the same
US20180243340A1 (en) * 2015-08-24 2018-08-30 University Of Houston System Combination therapy combining car + t cells with appropriately timed immunodulatory antibodies
US20190161530A1 (en) * 2016-04-07 2019-05-30 Bluebird Bio, Inc. Chimeric antigen receptor t cell compositions
EP3439675A4 (en) * 2016-04-08 2019-12-18 Purdue Research Foundation METHOD AND COMPOSITIONS FOR CAR-T CELL THERAPY
AU2017271550B2 (en) * 2016-05-25 2023-11-02 Endocyte, Inc. Method of treating cancer by targeting myeloid-derived suppressor cells
CN116474108A (zh) * 2016-12-14 2023-07-25 普渡研究基金会 成纤维细胞活化蛋白(fap)-靶向成像和治疗
CA3053534A1 (en) * 2017-02-17 2018-08-23 Purdue Research Foundation Targeted ligand-payload based drug delivery for cell therapy

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