JP2021531317A - Etv6またはfoxo1の発現を調節する中間体ノンコーディングrna制御因子を含む組成物およびその使用 - Google Patents
Etv6またはfoxo1の発現を調節する中間体ノンコーディングrna制御因子を含む組成物およびその使用 Download PDFInfo
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- JP2021531317A JP2021531317A JP2021504393A JP2021504393A JP2021531317A JP 2021531317 A JP2021531317 A JP 2021531317A JP 2021504393 A JP2021504393 A JP 2021504393A JP 2021504393 A JP2021504393 A JP 2021504393A JP 2021531317 A JP2021531317 A JP 2021531317A
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- expression
- etv6
- foxo1
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- coding rna
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- C—CHEMISTRY; METALLURGY
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1135—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against oncogenes or tumor suppressor genes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
- A61K31/7105—Natural ribonucleic acids, i.e. containing only riboses attached to adenine, guanine, cytosine or uracil and having 3'-5' phosphodiester links
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/11—Antisense
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/11—Antisense
- C12N2310/113—Antisense targeting other non-coding nucleic acids, e.g. antagomirs
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/14—Type of nucleic acid interfering nucleic acids [NA]
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/14—Type of nucleic acid interfering nucleic acids [NA]
- C12N2310/141—MicroRNAs, miRNAs
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/30—Chemical structure
- C12N2310/32—Chemical structure of the sugar
- C12N2310/323—Chemical structure of the sugar modified ring structure
- C12N2310/3233—Morpholino-type ring
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2320/00—Applications; Uses
- C12N2320/30—Special therapeutic applications
- C12N2320/31—Combination therapy
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Epidemiology (AREA)
- Toxicology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Cosmetics (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024076795A JP2024102292A (ja) | 2018-07-27 | 2024-05-09 | Etv6またはfoxo1の発現を調節する中間体ノンコーディングrna制御因子を含む組成物およびその使用 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1812334.9A GB201812334D0 (en) | 2018-07-27 | 2018-07-27 | Compositions and uses thereof |
| GB1812334.9 | 2018-07-27 | ||
| PCT/GB2019/052125 WO2020021291A1 (en) | 2018-07-27 | 2019-07-29 | Compositions comprising intermediate non-coding rna regulators modulating the expression of etv6 or foxo1 and uses thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024076795A Division JP2024102292A (ja) | 2018-07-27 | 2024-05-09 | Etv6またはfoxo1の発現を調節する中間体ノンコーディングrna制御因子を含む組成物およびその使用 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JP2021531317A true JP2021531317A (ja) | 2021-11-18 |
Family
ID=63518136
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021504393A Pending JP2021531317A (ja) | 2018-07-27 | 2019-07-29 | Etv6またはfoxo1の発現を調節する中間体ノンコーディングrna制御因子を含む組成物およびその使用 |
| JP2024076795A Pending JP2024102292A (ja) | 2018-07-27 | 2024-05-09 | Etv6またはfoxo1の発現を調節する中間体ノンコーディングrna制御因子を含む組成物およびその使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024076795A Pending JP2024102292A (ja) | 2018-07-27 | 2024-05-09 | Etv6またはfoxo1の発現を調節する中間体ノンコーディングrna制御因子を含む組成物およびその使用 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20210292765A1 (enExample) |
| EP (1) | EP3830111A1 (enExample) |
| JP (2) | JP2021531317A (enExample) |
| KR (1) | KR20210069626A (enExample) |
| CN (2) | CN120713925A (enExample) |
| AU (1) | AU2019309587B2 (enExample) |
| CA (1) | CA3107700A1 (enExample) |
| GB (1) | GB201812334D0 (enExample) |
| WO (1) | WO2020021291A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4328587A3 (en) * | 2018-02-13 | 2024-06-05 | Toray Industries, Inc. | Use of a kit or device and method for detecting dementia |
| CA3167206A1 (en) * | 2020-02-14 | 2021-10-07 | The Board Of Trustees Of The Leland Stanford Junior University | Pan-genotypic agents against respiratory viruses and methods of using the same |
| CN114159457B (zh) * | 2021-12-03 | 2023-08-22 | 温州医科大学 | 一种长链非编码rna、其结合蛋白及应用 |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2006505286A (ja) * | 2002-11-05 | 2006-02-16 | ノバルティス・フォルシュングスシュティフトゥング・ツヴァイクニーダーラッスング・フリードリッヒ・ミーシェー・インスティトゥート・フォー・バイオメディカル・リサーチ | 細胞増殖のtel/etv6−介在阻害 |
| JP2013253031A (ja) * | 2012-06-06 | 2013-12-19 | Nissei Bio Kk | 抗老化関連遺伝子転写促進剤 |
| WO2017192662A2 (en) * | 2016-05-03 | 2017-11-09 | Institute For Systems Biology | Methods for identifying treatment targets based on multiomics data |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1907016A2 (en) * | 2005-07-11 | 2008-04-09 | Irm, Llc | Methods and composition for modulating foxo1 activity and insulin signaling |
-
2018
- 2018-07-27 GB GBGB1812334.9A patent/GB201812334D0/en not_active Ceased
-
2019
- 2019-07-29 KR KR1020217006078A patent/KR20210069626A/ko not_active Ceased
- 2019-07-29 CA CA3107700A patent/CA3107700A1/en active Pending
- 2019-07-29 WO PCT/GB2019/052125 patent/WO2020021291A1/en not_active Ceased
- 2019-07-29 CN CN202411972083.0A patent/CN120713925A/zh active Pending
- 2019-07-29 EP EP19745738.5A patent/EP3830111A1/en active Pending
- 2019-07-29 CN CN201980064286.0A patent/CN113166214A/zh active Pending
- 2019-07-29 AU AU2019309587A patent/AU2019309587B2/en active Active
- 2019-07-29 US US17/263,465 patent/US20210292765A1/en active Pending
- 2019-07-29 JP JP2021504393A patent/JP2021531317A/ja active Pending
-
2024
- 2024-05-09 JP JP2024076795A patent/JP2024102292A/ja active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2006505286A (ja) * | 2002-11-05 | 2006-02-16 | ノバルティス・フォルシュングスシュティフトゥング・ツヴァイクニーダーラッスング・フリードリッヒ・ミーシェー・インスティトゥート・フォー・バイオメディカル・リサーチ | 細胞増殖のtel/etv6−介在阻害 |
| JP2013253031A (ja) * | 2012-06-06 | 2013-12-19 | Nissei Bio Kk | 抗老化関連遺伝子転写促進剤 |
| WO2017192662A2 (en) * | 2016-05-03 | 2017-11-09 | Institute For Systems Biology | Methods for identifying treatment targets based on multiomics data |
Non-Patent Citations (3)
| Title |
|---|
| KLOET D. E. ET AL., BIOCHIMICA ET BIOPHYSICA ACTA, vol. 1813(11), JPN6023021809, 2011, pages 1926 - 1937, ISSN: 0005071217 * |
| MCLOUGHLIN H. ET AL., HUMAN MOLECULAR GENETICS, vol. 23, no. 10, JPN6023021810, 2014, pages 2593 - 2603, ISSN: 0005373801 * |
| TIA N. ET AL., GENE, vol. 648, JPN6023021811, 4 February 2018 (2018-02-04), pages 97 - 105, ISSN: 0005071216 * |
Also Published As
| Publication number | Publication date |
|---|---|
| AU2019309587A1 (en) | 2021-02-18 |
| US20210292765A1 (en) | 2021-09-23 |
| CN120713925A (zh) | 2025-09-30 |
| WO2020021291A1 (en) | 2020-01-30 |
| EP3830111A1 (en) | 2021-06-09 |
| CA3107700A1 (en) | 2020-01-30 |
| KR20210069626A (ko) | 2021-06-11 |
| AU2019309587B2 (en) | 2024-09-19 |
| CN113166214A (zh) | 2021-07-23 |
| JP2024102292A (ja) | 2024-07-30 |
| GB201812334D0 (en) | 2018-09-12 |
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