JP2021528499A - 骨標的抗菌オキサゾリジノン関連化合物、その製剤及び用途 - Google Patents

骨標的抗菌オキサゾリジノン関連化合物、その製剤及び用途 Download PDF

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JP2021528499A
JP2021528499A JP2021521740A JP2021521740A JP2021528499A JP 2021528499 A JP2021528499 A JP 2021528499A JP 2021521740 A JP2021521740 A JP 2021521740A JP 2021521740 A JP2021521740 A JP 2021521740A JP 2021528499 A JP2021528499 A JP 2021528499A
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bisphosphonate
group
antibacterial agent
substituted
bone
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ホーロック エベティーノ、フランク
スン、シューティン
イー． マッケンナ、チャールズ
サドレラフィ、ケイヴァン
チェリアン、フィリップ
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    • A61L27/3604—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the human or animal origin of the biological material, e.g. hair, fascia, fish scales, silk, shellac, pericardium, pleura, renal tissue, amniotic membrane, parenchymal tissue, fetal tissue, muscle tissue, fat tissue, enamel
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    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
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    • C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
    • C07F9/3839—Polyphosphonic acids
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    • C07F9/3873—Polyphosphonic acids containing nitrogen substituent, e.g. N.....H or N-hydrocarbon group which can be substituted by halogen or nitro(so), N.....O, N.....S, N.....C(=X)- (X =O, S), N.....N, N...C(=X)...N (X =O, S)
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  • Oral & Maxillofacial Surgery (AREA)
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JP2021521740A 2018-06-26 2019-06-25 骨標的抗菌オキサゾリジノン関連化合物、その製剤及び用途 Pending JP2021528499A (ja)

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US201862690053P 2018-06-26 2018-06-26
US62/690,053 2018-06-26
PCT/US2019/039018 WO2020005964A1 (en) 2018-06-26 2019-06-25 Bone targeted antimicrobial oxazolidinone related compounds, formulations thereof, and uses thereof

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JP2021528499A true JP2021528499A (ja) 2021-10-21
JP2021528499A5 JP2021528499A5 (https=) 2022-07-05

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WO2007138381A2 (en) * 2005-10-14 2007-12-06 Targanta Therapeutics Inc. Phosphonated oxazolidinones and uses thereof for the prevention and treatment of bone and joint infections
JP2008536911A (ja) * 2005-04-21 2008-09-11 ターガンタ セラピュティクス，インコーポレイティド ホスホン酸処理フルオロキノロン、その抗菌類似体および骨および関節感染の予防および治療方法
WO2010086421A1 (en) * 2009-01-30 2010-08-05 Mero S.R.L. Antibacterial hydrogel and use thereof in orthopedics
WO2011037731A1 (en) * 2009-09-25 2011-03-31 Anacor Pharmaceuticals, Inc. Boron containing small molecules
WO2017210611A1 (en) * 2016-06-03 2017-12-07 Biovinc, Llc. Bisphosphonate quinolone conjugates and uses thereof

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US8586781B2 (en) 1998-04-02 2013-11-19 Mbc Pharma, Inc. Bone targeted therapeutics and methods of making and using the same
TW200410701A (en) * 2002-10-15 2004-07-01 Novartis Ag Method of administering bisphosphonates
CA3105829A1 (en) * 2018-07-09 2020-01-16 Biovinc, Llc. Bisphosphonate quinolone conjugates and uses thereof

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
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