JP2021528455A5 - - Google Patents
Info
- Publication number
- JP2021528455A5 JP2021528455A5 JP2020572638A JP2020572638A JP2021528455A5 JP 2021528455 A5 JP2021528455 A5 JP 2021528455A5 JP 2020572638 A JP2020572638 A JP 2020572638A JP 2020572638 A JP2020572638 A JP 2020572638A JP 2021528455 A5 JP2021528455 A5 JP 2021528455A5
- Authority
- JP
- Japan
- Prior art keywords
- ethyl
- pyridine
- methoxyazetidine
- methoxy
- cyclopropyl
- Prior art date
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP18180114.3 | 2018-06-27 | ||
| EP18180114 | 2018-06-27 | ||
| PCT/EP2019/066733 WO2020002270A1 (en) | 2018-06-27 | 2019-06-25 | Pyridine and pyrazine derivatives as preferential cannabinoid 2 agonists |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2021528455A JP2021528455A (ja) | 2021-10-21 |
| JP2021528455A5 true JP2021528455A5 (https=) | 2022-06-30 |
| JPWO2020002270A5 JPWO2020002270A5 (https=) | 2022-06-30 |
| JP7454512B2 JP7454512B2 (ja) | 2024-03-22 |
Family
ID=62814859
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020572638A Active JP7454512B2 (ja) | 2018-06-27 | 2019-06-25 | 優先的カンナビノイド２アゴニストとしてのピリジン及びピラジン誘導体 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US11655243B2 (https=) |
| EP (1) | EP3814337B1 (https=) |
| JP (1) | JP7454512B2 (https=) |
| CN (1) | CN112074513B (https=) |
| WO (1) | WO2020002270A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR112199A1 (es) | 2017-06-20 | 2019-10-02 | Hoffmann La Roche | Derivados de piridina como agonistas inversos del receptor cannabinoide 2 |
| PE20210368A1 (es) | 2018-06-27 | 2021-02-26 | Eth Zuerich | Nuevos compuestos de piridina y pirazina como inhibidores del receptor cannabinoide 2 |
| JP7456948B2 (ja) | 2018-06-27 | 2024-03-27 | エフ． ホフマン－ラ ロシュ アーゲー | 放射性標識カンナビノイド受容体２リガンド |
| CN112119068A (zh) | 2018-06-27 | 2020-12-22 | 豪夫迈·罗氏有限公司 | 作为大麻素受体2的抑制剂的新型氮杂环丁烷-取代的吡啶和吡嗪化合物 |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW200808769A (en) * | 2006-04-18 | 2008-02-16 | Astrazeneca Ab | Therapeutic compounds |
| WO2008040649A2 (en) * | 2006-10-04 | 2008-04-10 | F. Hoffmann-La Roche Ag | Pyrazine-2-carboxamide derivatives as cb2 receptor modulators |
| WO2009106561A1 (en) * | 2008-02-27 | 2009-09-03 | Biovitrum Ab (Publ) | Pyrazine compounds for treating gpr119 related disorders |
| US9321727B2 (en) * | 2011-06-10 | 2016-04-26 | Hoffmann-La Roche Inc. | Pyridine derivatives as agonists of the CB2 receptor |
| MX2014001862A (es) * | 2011-09-12 | 2014-05-30 | Hoffmann La Roche | 5-cicloalquil-o 5-heterociclil-nicotinamidas. |
| TW201326139A (zh) * | 2011-10-28 | 2013-07-01 | Hoffmann La Roche | 新穎吡□衍生物 |
| US9403808B2 (en) * | 2011-10-28 | 2016-08-02 | Hoffmann-La Roche Inc. | Pyrazine derivatives |
| CN104837818B (zh) | 2012-12-07 | 2017-07-14 | 霍夫曼-拉罗奇有限公司 | 可用作cb2激动剂的吡啶‑2‑酰胺 |
| AU2013354115B2 (en) | 2012-12-07 | 2017-10-05 | F. Hoffmann-La Roche Ag | Novel pyrazine derivatives as CB2 receptor agonists |
| SG10201800170YA (en) | 2012-12-07 | 2018-02-27 | Hoffmann La Roche | Novel pyridine derivatives |
| PL2928868T3 (pl) * | 2012-12-07 | 2017-12-29 | F.Hoffmann-La Roche Ag | Pirydyno-2-amidy użyteczne jako agoniści cb2 |
| CN105121436B (zh) | 2013-03-26 | 2018-07-27 | 豪夫迈·罗氏有限公司 | 新的吡啶衍生物 |
| WO2015150440A1 (en) * | 2014-04-04 | 2015-10-08 | F. Hoffmann-La Roche Ag | Pyridine-2-amides useful as cb2 agonists |
| CN111170938A (zh) * | 2014-04-04 | 2020-05-19 | 豪夫迈·罗氏有限公司 | 作为大麻素受体激动剂的5,6-双取代的吡啶-2-甲酰胺 |
| EP3386951B1 (en) | 2015-12-09 | 2020-02-26 | H. Hoffnabb-La Roche Ag | Phenyl derivatives as cannabinoid receptor 2 agonists |
| AR112199A1 (es) | 2017-06-20 | 2019-10-02 | Hoffmann La Roche | Derivados de piridina como agonistas inversos del receptor cannabinoide 2 |
| PE20210368A1 (es) | 2018-06-27 | 2021-02-26 | Eth Zuerich | Nuevos compuestos de piridina y pirazina como inhibidores del receptor cannabinoide 2 |
| CN112119068A (zh) | 2018-06-27 | 2020-12-22 | 豪夫迈·罗氏有限公司 | 作为大麻素受体2的抑制剂的新型氮杂环丁烷-取代的吡啶和吡嗪化合物 |
| JP7456948B2 (ja) | 2018-06-27 | 2024-03-27 | エフ． ホフマン－ラ ロシュ アーゲー | 放射性標識カンナビノイド受容体２リガンド |
| TWI687701B (zh) | 2018-12-05 | 2020-03-11 | 宏碁股份有限公司 | 判斷電量狀態的方法及其電子裝置 |
-
2019
- 2019-06-25 EP EP19739206.1A patent/EP3814337B1/en active Active
- 2019-06-25 JP JP2020572638A patent/JP7454512B2/ja active Active
- 2019-06-25 CN CN201980029322.XA patent/CN112074513B/zh active Active
- 2019-06-25 WO PCT/EP2019/066733 patent/WO2020002270A1/en not_active Ceased
-
2020
- 2020-12-17 US US17/125,647 patent/US11655243B2/en active Active
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