JP2021527669A - 線維症の軽減又は治療のための組成物及び方法 - Google Patents

線維症の軽減又は治療のための組成物及び方法 Download PDF

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Publication number
JP2021527669A
JP2021527669A JP2020570744A JP2020570744A JP2021527669A JP 2021527669 A JP2021527669 A JP 2021527669A JP 2020570744 A JP2020570744 A JP 2020570744A JP 2020570744 A JP2020570744 A JP 2020570744A JP 2021527669 A JP2021527669 A JP 2021527669A
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Prior art keywords
amino acid
composition
acid entity
entity
salt
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JP2020570744A
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English (en)
Japanese (ja)
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JP2021527669A5 (https=
JPWO2019246298A5 (https=
Inventor
ハミル,マイケル
アフェヤン,ラフィー
リ,チョン−ウェイ
ルイサード,ハリー
ハム,ルーク,エス
マルキアン,スヴェトラナ
ダウ,ナディン
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Axcella Health Inc
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Axcella Health Inc
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Publication of JP2021527669A publication Critical patent/JP2021527669A/ja
Publication of JP2021527669A5 publication Critical patent/JP2021527669A5/ja
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Withdrawn legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17Amino acids, peptides or proteins
    • A23L33/175Amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/02Peptides of undefined number of amino acids; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Food Science & Technology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Polymers & Plastics (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
  • Neurology (AREA)
  • Nutrition Science (AREA)
  • Pulmonology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP2020570744A 2018-06-20 2019-06-19 線維症の軽減又は治療のための組成物及び方法 Withdrawn JP2021527669A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201862687718P 2018-06-20 2018-06-20
US62/687,718 2018-06-20
US201862758174P 2018-11-09 2018-11-09
US62/758,174 2018-11-09
US201962794154P 2019-01-18 2019-01-18
US62/794,154 2019-01-18
PCT/US2019/038036 WO2019246298A1 (en) 2018-06-20 2019-06-19 Compositions and methods for the reduction or treatment of fibrosis

Publications (3)

Publication Number Publication Date
JP2021527669A true JP2021527669A (ja) 2021-10-14
JP2021527669A5 JP2021527669A5 (https=) 2022-09-02
JPWO2019246298A5 JPWO2019246298A5 (https=) 2022-09-02

Family

ID=67253997

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020570744A Withdrawn JP2021527669A (ja) 2018-06-20 2019-06-19 線維症の軽減又は治療のための組成物及び方法

Country Status (6)

Country Link
US (1) US20210275480A1 (https=)
EP (1) EP3810272A1 (https=)
JP (1) JP2021527669A (https=)
CN (1) CN112839708A (https=)
MA (1) MA52960A (https=)
WO (1) WO2019246298A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JOP20190146A1 (ar) 2016-12-19 2019-06-18 Axcella Health Inc تركيبات حمض أميني وطرق لمعالجة أمراض الكبد
CN112823018A (zh) 2018-06-20 2021-05-18 胺细拉健康公司 制备氨基酸组合物的方法
WO2023009444A1 (en) * 2021-07-26 2023-02-02 Axcella Health Inc. Amino acid compositions and methods for use in the treatment of post-acute sequelae of covid-19

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070286909A1 (en) * 2006-06-07 2007-12-13 Daniel S. Smith Amino acid compositions
US9884899B2 (en) * 2007-07-06 2018-02-06 Promedior, Inc. Methods for treating fibrosis using CRP antagonists
KR20090028880A (ko) * 2007-09-17 2009-03-20 재단법인서울대학교산학협력재단 섬유증 예방 또는 치료용 약제학적 조성물
US20150080320A1 (en) * 2012-05-16 2015-03-19 Aadigen, Llc Multi-target modulation for treating fibrosis and inflammatory conditions
WO2015061607A1 (en) * 2013-10-23 2015-04-30 Whitehead Institute For Biomedical Research Mtorc1 modulation by amino acids and uses thereof

Also Published As

Publication number Publication date
EP3810272A1 (en) 2021-04-28
US20210275480A1 (en) 2021-09-09
WO2019246298A1 (en) 2019-12-26
CN112839708A (zh) 2021-05-25
MA52960A (fr) 2021-04-28

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