JP2021523139A - 腎石症の進行を遅らせるための組成物および方法 - Google Patents
腎石症の進行を遅らせるための組成物および方法 Download PDFInfo
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Classifications
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- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/04—Drugs for disorders of the urinary system for urolithiasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y301/00—Hydrolases acting on ester bonds (3.1)
- C12Y301/04—Phosphoric diester hydrolases (3.1.4)
- C12Y301/04001—Phosphodiesterase I (3.1.4.1)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y306/00—Hydrolases acting on acid anhydrides (3.6)
- C12Y306/01—Hydrolases acting on acid anhydrides (3.6) in phosphorus-containing anhydrides (3.6.1)
- C12Y306/01009—Nucleotide diphosphatase (3.6.1.9), i.e. nucleotide-pyrophosphatase
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/31—Fusion polypeptide fusions, other than Fc, for prolonged plasma life, e.g. albumin
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/50—Fusion polypeptide containing protease site
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
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| US201862668293P | 2018-05-08 | 2018-05-08 | |
| US62/668,293 | 2018-05-08 | ||
| PCT/US2019/031049 WO2019217373A1 (en) | 2018-05-08 | 2019-05-07 | Compositions and methods for reducing progression of nephrolithiasis |
Publications (3)
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| JP2021523139A true JP2021523139A (ja) | 2021-09-02 |
| JP2021523139A5 JP2021523139A5 (https=) | 2022-05-13 |
| JPWO2019217373A5 JPWO2019217373A5 (https=) | 2022-05-13 |
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| JP2020562598A Pending JP2021523139A (ja) | 2018-05-08 | 2019-05-07 | 腎石症の進行を遅らせるための組成物および方法 |
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| US (1) | US12157903B2 (https=) |
| EP (1) | EP3790628A4 (https=) |
| JP (1) | JP2021523139A (https=) |
| AU (1) | AU2019267545A1 (https=) |
| CA (1) | CA3099266A1 (https=) |
| WO (1) | WO2019217373A1 (https=) |
Cited By (1)
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| KR20240012623A (ko) * | 2022-07-19 | 2024-01-30 | 가천대학교 산학협력단 | 바이오마커 enpp7의 당뇨병의 진단 및 치료 용도 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| EP3687565A1 (en) | 2017-09-27 | 2020-08-05 | Alexion Pharmaceuticals, Inc. | Methods of improving cardiovascular function and treating cardiovascular disease using a recombinant ectonucleotide pyrophosphatase phosphodiesterase (npp1) |
| EP3844280A4 (en) | 2018-08-31 | 2022-09-14 | Yale University | ENPP1 POLYPEPTIDES AND METHODS OF USE |
| CN116406281A (zh) * | 2020-05-27 | 2023-07-07 | 依诺兹梅制药公司 | 用于治疗外周动脉疾病的组合物和方法 |
| KR20230047334A (ko) * | 2020-05-27 | 2023-04-07 | 이노자임 파마, 인코포레이티드 | 혈관 평활근 세포 증식을 억제하기 위한 조성물 및 방법 |
| IL298853A (en) * | 2020-06-09 | 2023-02-01 | Inozyme Pharma Inc | Soluble enpp1 or enpp3 proteins and uses thereof |
| CA3246877A1 (en) * | 2022-03-30 | 2023-10-05 | Yale University | METHOD AND COMPOSITIONS FOR THE TREATMENT, ALLEVIATION AND/OR PREVENTION OF DIFFUSE IDIOPATHIC SKELETAL HYPEROSTOSIS (DISH) |
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| JPH04292169A (ja) | 1991-03-19 | 1992-10-16 | Sekisui Chem Co Ltd | ハイブリッド型人工膵臓 |
| AU1518595A (en) | 1994-01-14 | 1995-08-01 | Genentech Inc. | Antagonists to insulin receptor tyrosine kinase inhibitor |
| WO2002039994A2 (en) * | 2000-11-20 | 2002-05-23 | University Of Kansas Medical Center | Methods for the treatment and prevention of urinary stone disease |
| CA2462653C (en) | 2001-11-07 | 2016-06-07 | Aya Jakobovits | Nucleic acid and corresponding protein entitled 161p2f10b useful in treatment and detection of cancer |
| US9055984B2 (en) | 2004-04-21 | 2015-06-16 | DePuy Synthes Products, Inc. | Sternal reconstruction system |
| JP5199077B2 (ja) * | 2005-06-10 | 2013-05-15 | アルタス ファーマシューティカルズ インコーポレイテッド | シュウ酸オキシダーゼ結晶の投与による、シュウ酸塩濃度を低下させるための方法 |
| PT2046373E (pt) | 2006-08-02 | 2013-05-06 | Althea Technologies Inc | Oxalato descarboxilase cristalizada e métodos de utilização |
| WO2009030254A1 (en) * | 2007-09-04 | 2009-03-12 | Curevac Gmbh | Complexes of rna and cationic peptides for transfection and for immunostimulation |
| JP2014509617A (ja) | 2011-03-29 | 2014-04-21 | ベタ−セル エンフェー | 治療薬のカプセル化方法、およびその使用 |
| WO2014126965A2 (en) | 2013-02-13 | 2014-08-21 | Yale University | Compositions and methods for treating pathological calcification and ossification |
| US20160184458A1 (en) * | 2013-03-14 | 2016-06-30 | Shire Human Genetic Therapies, Inc. | Mrna therapeutic compositions and use to treat diseases and disorders |
| CN105378075B (zh) | 2013-03-15 | 2022-04-05 | Atyr 医药公司 | 组氨酰-trna合成酶-fc缀合物 |
| CA2924259C (en) | 2013-09-19 | 2021-12-21 | Universitatsspital Basel | Artificial vascular graft |
| EP3234116B1 (en) * | 2014-12-19 | 2021-09-08 | Alexion Pharmaceuticals, Inc. | Methods of treating tissue calcification |
| KR20250078598A (ko) * | 2015-05-19 | 2025-06-02 | 예일 유니버시티 | 병리학적 석회화 병태를 치료하기 위한 조성물, 및 이의 사용 방법 |
| JP6543119B2 (ja) | 2015-07-10 | 2019-07-10 | 有限会社Ptmc研究所 | ステントグラフト |
| EP3452101A2 (en) * | 2016-05-04 | 2019-03-13 | CureVac AG | Rna encoding a therapeutic protein |
| BR112019002355A2 (pt) * | 2016-08-05 | 2019-07-16 | Yale University | composições e métodos para prevenção de acidente vascular cerebral em pacientes pediátricos com anemia falciforme |
| US20180085492A1 (en) | 2016-09-29 | 2018-03-29 | Northwestern University | Antioxidant scaffolds for beta cell delivery |
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2019
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- 2019-05-07 EP EP19798912.2A patent/EP3790628A4/en not_active Withdrawn
- 2019-05-07 AU AU2019267545A patent/AU2019267545A1/en not_active Abandoned
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20240012623A (ko) * | 2022-07-19 | 2024-01-30 | 가천대학교 산학협력단 | 바이오마커 enpp7의 당뇨병의 진단 및 치료 용도 |
| KR20240109228A (ko) * | 2022-07-19 | 2024-07-10 | 가천대학교 산학협력단 | 바이오마커 enpp7의 당뇨병의 진단 및 치료 용도 |
| KR102748577B1 (ko) | 2022-07-19 | 2025-01-06 | 가천대학교 산학협력단 | 바이오마커 enpp7의 당뇨병의 진단 및 치료 용도 |
| KR102820683B1 (ko) | 2022-07-19 | 2025-06-17 | 가천대학교 산학협력단 | 바이오마커 enpp7의 당뇨병의 진단 및 치료 용도 |
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| Publication number | Publication date |
|---|---|
| US12157903B2 (en) | 2024-12-03 |
| WO2019217373A1 (en) | 2019-11-14 |
| AU2019267545A1 (en) | 2020-11-26 |
| EP3790628A1 (en) | 2021-03-17 |
| CA3099266A1 (en) | 2019-11-14 |
| US20210363506A1 (en) | 2021-11-25 |
| EP3790628A4 (en) | 2022-03-09 |
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