JP2021519812A - 抗菌性光増感剤の組成と方法 - Google Patents

抗菌性光増感剤の組成と方法 Download PDF

Info

Publication number
JP2021519812A
JP2021519812A JP2020563666A JP2020563666A JP2021519812A JP 2021519812 A JP2021519812 A JP 2021519812A JP 2020563666 A JP2020563666 A JP 2020563666A JP 2020563666 A JP2020563666 A JP 2020563666A JP 2021519812 A JP2021519812 A JP 2021519812A
Authority
JP
Japan
Prior art keywords
composition
photosensitizer
light
wavelength
microbial infection
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2020563666A
Other languages
English (en)
Japanese (ja)
Other versions
JP2021519812A5 (enExample
Inventor
イツァーキ ヴァン—ハム、イリット
イツァーキ ヴァン―ハム、イリット
Original Assignee
トウエフエックス インク．
トウエフエックス インク．
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by トウエフエックス インク．, トウエフエックス インク． filed Critical トウエフエックス インク．
Publication of JP2021519812A publication Critical patent/JP2021519812A/ja
Publication of JP2021519812A5 publication Critical patent/JP2021519812A5/ja
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/5415—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/287—Chrysanthemum, e.g. daisy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N5/0613—Apparatus adapted for a specific treatment
    • A61N5/062—Photodynamic therapy, i.e. excitation of an agent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N5/0613—Apparatus adapted for a specific treatment
    • A61N5/0624—Apparatus adapted for a specific treatment for eliminating microbes, germs, bacteria on or in the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M2037/0007—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin having means for enhancing the permeation of substances through the epidermis, e.g. using suction or depression, electric or magnetic fields, sound waves or chemical agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/05—General characteristics of the apparatus combined with other kinds of therapy
    • A61M2205/051—General characteristics of the apparatus combined with other kinds of therapy with radiation therapy
    • A61M2205/052—General characteristics of the apparatus combined with other kinds of therapy with radiation therapy infrared
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N2005/065—Light sources therefor
    • A61N2005/0651—Diodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N2005/0658—Radiation therapy using light characterised by the wavelength of light used
    • A61N2005/0659—Radiation therapy using light characterised by the wavelength of light used infrared
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N2005/0658—Radiation therapy using light characterised by the wavelength of light used
    • A61N2005/0662—Visible light
    • A61N2005/0663—Coloured light
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N5/067—Radiation therapy using light using laser light
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medical Informatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Organic Chemistry (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Anesthesiology (AREA)
  • Biophysics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2020563666A 2018-03-12 2019-03-12 抗菌性光増感剤の組成と方法 Pending JP2021519812A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862641685P 2018-03-12 2018-03-12
US62/641,685 2018-03-12
PCT/CA2019/050298 WO2019173907A1 (en) 2018-03-12 2019-03-12 Antimicrobial photosensitizer composition and method

Publications (2)

Publication Number Publication Date
JP2021519812A true JP2021519812A (ja) 2021-08-12
JP2021519812A5 JP2021519812A5 (enExample) 2022-11-01

Family

ID=67908673

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020563666A Pending JP2021519812A (ja) 2018-03-12 2019-03-12 抗菌性光増感剤の組成と方法

Country Status (6)

Country Link
US (1) US20210046137A1 (enExample)
EP (1) EP3765081B1 (enExample)
JP (1) JP2021519812A (enExample)
AU (1) AU2019235631B2 (enExample)
CA (1) CA3067761C (enExample)
WO (1) WO2019173907A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023193103A1 (en) * 2022-04-05 2023-10-12 Toefx Inc. Combined photodisinfection and visualization device
AU2023316094A1 (en) * 2022-07-28 2024-07-25 Toefx Inc. Diagnostic and treatment methods for onychomycosis

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090234270A1 (en) * 2008-03-11 2009-09-17 Ondine International, Ltd. Therapy and device for treatment of nail infections
WO2012090194A2 (en) * 2010-12-29 2012-07-05 Abrham Galya Compositions and methods for treating a skin disorder

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL57393A0 (en) * 1978-05-31 1979-09-30 Debat Lab Inula extract its preparation and pharmaceutical compositions containing it
JP2005167551A (ja) * 2003-12-02 2005-06-23 Fuji Xerox Co Ltd 画像形成装置、校正方法及びそのプログラム
WO2005117925A1 (en) * 2004-06-01 2005-12-15 Avisco Ltd. Novel inula viscosa extracts and their use for treatment of arthritis
US20090233914A1 (en) * 2008-03-11 2009-09-17 Ondine International, Ltd. Composition for treatment of nail infections
EP3463268B1 (en) * 2016-05-23 2021-11-03 Klox Technologies Limited Biophotonic compositions and uses thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090234270A1 (en) * 2008-03-11 2009-09-17 Ondine International, Ltd. Therapy and device for treatment of nail infections
WO2012090194A2 (en) * 2010-12-29 2012-07-05 Abrham Galya Compositions and methods for treating a skin disorder

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
FRONTIERS IN MICROBIOLOGY, vol. 6, JPN6023004052, 2015, pages 202 - 1, ISSN: 0005144484 *
JOURNAL OF FOOD SAFETY, vol. 36, JPN6023004050, 2016, pages 77 - 88, ISSN: 0004983396 *
PHARMACEUTICAL BIOLOGY, vol. 39, no. 5, JPN6023004051, 2001, pages 364 - 374, ISSN: 0005144483 *

Also Published As

Publication number Publication date
CA3067761C (en) 2023-09-26
AU2019235631A1 (en) 2020-10-15
EP3765081B1 (en) 2023-11-22
US20210046137A1 (en) 2021-02-18
CA3067761A1 (en) 2019-09-19
EP3765081A4 (en) 2022-02-23
WO2019173907A1 (en) 2019-09-19
AU2019235631B2 (en) 2024-05-23
EP3765081C0 (en) 2023-11-22
EP3765081A1 (en) 2021-01-20

Similar Documents

Publication Publication Date Title
Carrera et al. The application of antimicrobial photodynamic therapy (aPDT) in dentistry: a critical review
Calzavara‐Pinton et al. Photodynamic antifungal chemotherapy
Kharkwal et al. Photodynamic therapy for infections: clinical applications
Paschoal et al. Photodynamic potential of curcumin and blue LED against Streptococcus mutans in a planktonic culture
AU750933B2 (en) Phototherapy based method for treating pathogens and composition for effecting same
Reis et al. Scientific evidence in antimicrobial photodynamic therapy: An alternative approach for reducing cariogenic bacteria
Pileggi et al. Blue light-mediated inactivation of Enterococcus faecalis in vitro
Azizi et al. Effect of photodynamic therapy with two photosensitizers on Candida albicans
Fekrazad et al. Photoelimination of Streptococcus mutans with two methods of photodynamic and photothermal therapy
Rosa et al. Antimicrobial photodynamic therapy: a new therapeutic option to combat infections
Gonçalves Photophysical properties and therapeutic use of natural photosensitizers
US20090234270A1 (en) Therapy and device for treatment of nail infections
Fekrazad et al. Eradication of C. albicans and T. rubrum with photoactivated indocyanine green, Citrus aurantifolia essential oil and fluconazole
KR20110133032A (ko) 광역동 살균용 조성물
Cantisani et al. Overview on Topical 5‐ALA Photodynamic Therapy Use for Non Melanoma Skin Cancers
Gupta et al. Divulging the potency of naturally derived photosensitizers in green PDT: an inclusive review of mechanisms, advantages, and future prospects
CN106620695A (zh) 一种用于光动力杀菌的光敏药物制剂及其用途
CA3067761C (en) Antimicrobial photosensitizer compositions comprising an inula viscosa extract
JP2021519812A5 (enExample)
WO2008109424A1 (en) Composition, therapy and device for treatment of nail infections
Yook et al. In vitro study on the effects of photodynamic inactivation using methyl pheophorbide a, PhotoMed, PhotoCure, and 660 nm diode laser on Candida albicans
Pogorelaya et al. Riboflavin in photodynamic inactivation of pathogens and photodynamic therapy
Calabrò et al. in the treatment of superficial mycoses: an evidence-based evaluation
Mariano et al. Singlet oxygen release due to different concentrations of photosensitizer
Tionardus et al. Photosensitizer in periodontal antimicrobial photodynamic therapy: a literature review

Legal Events

Date Code Title Description
A917 Reason for reinstatement of right to file examination request

Free format text: JAPANESE INTERMEDIATE CODE: A917

Effective date: 20201105

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20220304

A524 Written submission of copy of amendment under article 19 pct

Free format text: JAPANESE INTERMEDIATE CODE: A524

Effective date: 20220607

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20230131

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20230207

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20230502

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20230905