JP2021519069A - 遺伝子改変リンパ球の製造方法 - Google Patents
遺伝子改変リンパ球の製造方法 Download PDFInfo
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- JP2021519069A JP2021519069A JP2020551499A JP2020551499A JP2021519069A JP 2021519069 A JP2021519069 A JP 2021519069A JP 2020551499 A JP2020551499 A JP 2020551499A JP 2020551499 A JP2020551499 A JP 2020551499A JP 2021519069 A JP2021519069 A JP 2021519069A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/10—Cellular immunotherapy characterised by the cell type used
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- A61K40/46—Viral antigens
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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- A61P31/18—Antivirals for RNA viruses for HIV
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- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
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- C12N15/86—Viral vectors
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0636—T lymphocytes
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- C12N2310/141—MicroRNAs, miRNAs
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- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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- C12N2740/16041—Use of virus, viral particle or viral elements as a vector
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- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16211—Human Immunodeficiency Virus, HIV concerning HIV gagpol
- C12N2740/16234—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Virology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Cell Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- Mycology (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Tropical Medicine & Parasitology (AREA)
- Plant Pathology (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- AIDS & HIV (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024046892A JP2024073653A (ja) | 2018-03-27 | 2024-03-22 | 遺伝子改変リンパ球の製造方法 |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862648804P | 2018-03-27 | 2018-03-27 | |
| US62/648,804 | 2018-03-27 | ||
| PCT/US2019/024410 WO2019191314A1 (en) | 2018-03-27 | 2019-03-27 | Methods of manufacturing genetically-modified lymphocytes |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024046892A Division JP2024073653A (ja) | 2018-03-27 | 2024-03-22 | 遺伝子改変リンパ球の製造方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2021519069A true JP2021519069A (ja) | 2021-08-10 |
| JP2021519069A5 JP2021519069A5 (https=) | 2022-04-04 |
Family
ID=68058501
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020551499A Pending JP2021519069A (ja) | 2018-03-27 | 2019-03-27 | 遺伝子改変リンパ球の製造方法 |
| JP2024046892A Pending JP2024073653A (ja) | 2018-03-27 | 2024-03-22 | 遺伝子改変リンパ球の製造方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024046892A Pending JP2024073653A (ja) | 2018-03-27 | 2024-03-22 | 遺伝子改変リンパ球の製造方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US20210015868A1 (https=) |
| EP (1) | EP3773622A4 (https=) |
| JP (2) | JP2021519069A (https=) |
| KR (1) | KR20200135852A (https=) |
| WO (1) | WO2019191314A1 (https=) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017139065A1 (en) | 2016-02-08 | 2017-08-17 | American Gene Technologies International Inc. | Hiv vaccination and immunotherapy |
| AU2017292582C1 (en) | 2016-07-08 | 2021-11-11 | American Gene Technologies International Inc. | HIV pre-immunization and immunotherapy |
| KR20200135852A (ko) * | 2018-03-27 | 2020-12-03 | 아메리칸 진 테크놀로지스 인터내셔널 인코포레이티드 | 유전자 변형 림프구의 제조 방법 |
| WO2021011882A1 (en) * | 2019-07-17 | 2021-01-21 | Case Western Reserve University | Long lived t cells for treating hiv infection |
| WO2021178571A1 (en) * | 2020-03-03 | 2021-09-10 | American Gene Technologies International Inc. | On demand expression of exogenous factors in lymphocytes to treat hiv |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017139065A1 (en) * | 2016-02-08 | 2017-08-17 | American Gene Technologies International Inc. | Hiv vaccination and immunotherapy |
| WO2018025923A1 (ja) * | 2016-08-03 | 2018-02-08 | 国立大学法人鹿児島大学 | 抗htlv-1剤、htlv-1関連脊髄症(ham/tsp)治療薬 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2946312A1 (en) * | 2014-04-23 | 2015-10-29 | Juno Therapeutics, Inc. | Methods for isolating, culturing, and genetically engineering immune cell populations for adoptive therapy |
| CN107405357B (zh) * | 2014-10-14 | 2021-12-31 | 德克萨斯科技大学系统 | 多重shRNAs及其应用 |
| GB201509202D0 (en) * | 2015-05-28 | 2015-07-15 | Ge Healthcare Bio Sciences Ab | Semi-static cell culture |
| EP3319631A4 (en) * | 2015-07-08 | 2019-01-09 | American Gene Technologies International Inc. | HIV PREMUNICATION AND IMMUNOTHERAPY |
| AU2017292582C1 (en) * | 2016-07-08 | 2021-11-11 | American Gene Technologies International Inc. | HIV pre-immunization and immunotherapy |
| JP7260170B2 (ja) * | 2017-01-09 | 2023-04-18 | アメリカン ジーン テクノロジーズ インターナショナル インコーポレイテッド | 事前の免疫化ステップのないhiv免疫療法 |
| KR20200135852A (ko) * | 2018-03-27 | 2020-12-03 | 아메리칸 진 테크놀로지스 인터내셔널 인코포레이티드 | 유전자 변형 림프구의 제조 방법 |
-
2019
- 2019-03-27 KR KR1020207030636A patent/KR20200135852A/ko not_active Ceased
- 2019-03-27 JP JP2020551499A patent/JP2021519069A/ja active Pending
- 2019-03-27 WO PCT/US2019/024410 patent/WO2019191314A1/en not_active Ceased
- 2019-03-27 EP EP19777212.2A patent/EP3773622A4/en active Pending
- 2019-03-27 US US17/042,043 patent/US20210015868A1/en not_active Abandoned
-
2023
- 2023-07-28 US US18/227,747 patent/US20240115604A1/en not_active Abandoned
-
2024
- 2024-03-22 JP JP2024046892A patent/JP2024073653A/ja active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017139065A1 (en) * | 2016-02-08 | 2017-08-17 | American Gene Technologies International Inc. | Hiv vaccination and immunotherapy |
| WO2018025923A1 (ja) * | 2016-08-03 | 2018-02-08 | 国立大学法人鹿児島大学 | 抗htlv-1剤、htlv-1関連脊髄症(ham/tsp)治療薬 |
Non-Patent Citations (1)
| Title |
|---|
| "CD4+ T CELL ISOLATION KIT HUMAN", [ONLINE], 2015年公開, MILTENYI BIOTEC, [2023.3.6 検索], インター, JPN7023000970, ISSN: 0005372951 * |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2019191314A1 (en) | 2019-10-03 |
| JP2024073653A (ja) | 2024-05-29 |
| EP3773622A4 (en) | 2021-12-01 |
| US20240115604A1 (en) | 2024-04-11 |
| US20210015868A1 (en) | 2021-01-21 |
| KR20200135852A (ko) | 2020-12-03 |
| EP3773622A1 (en) | 2021-02-17 |
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