JP2021511145A - パルス型または共鳴型洗浄シリンジ - Google Patents
パルス型または共鳴型洗浄シリンジ Download PDFInfo
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Abstract
Description
本出願は、2018年1月28日に出願された米国仮特許出願第62/622,907号からの35USC§119(e)に基づく優先権を主張し、その内容(これに伴って提出されたすべての添付書類を含む)は、その全体が参照によりここに組み込まれる。
一般に、本開示の例示的な実施形態は、血管アクセス装置、特に静脈内(IV)カテーテルの維持に使用するための洗浄装置の分野に関する。
医療応用の例では、感染の潜在的な源である閉塞を防止するために、および/または細菌を清浄化してIVカテーテルの細菌コロニー化を防止するために、様々な手順がIVカテーテルの洗浄に使用されている。非特許文献1(Agnes Ferroniet al. “Pulsative Flushing As A Strategy To Prevent Bacterial Colonization Of Vascular Access Devices”(Medical Devices: Evidence and Research 2014:7 379-383, Doverpress 2004)(参照により本明細書に組み込まれる全体の開示)が挙げられ、時々「開始−停止」洗浄と呼ばれるパルス状の流れを使用して、シリンジプランジャに高い力と低い力を交互に印加することにより、連続的な(一定流量の)洗浄と比較して、IVカテーテルから細菌を清浄化するのに2倍以上効果的であることを実証している。
この詳細な説明で例示される事項は、本開示の例示的な実施形態を包括的に理解するのを助けるために提供される。したがって、当技術分野の当業者は、ここに記載された実施形態の様々な変更および修正が、本開示の範囲および精神から逸脱することなく行われ得ることを認識するであろう。また、周知の機能および構造の説明は、明確さおよび簡潔さのために省略されている。
本明細書で例示される事項は、添付の図面を参照して例示的な実施形態の包括的な理解を助けるために提供される。したがって、当技術分野の通常の当業者であれば、ここに記載された例示的な実施形態の様々な変更および修正が、それらの全範囲および等価物から逸脱することなく、添付の特許請求の範囲の範囲内で行われ得ることを認識するであろう。また、周知の機能および構造の説明は、明確さおよび簡潔さのために省略されている。同様に、本開示の文脈で使用される特定の命名規則、ラベル、および用語は、非限定的であり、例示的な実施形態の理解を容易にするための例示的な目的のためにのみ提供される。
Claims (15)
- 洗浄シリンジであって:
基端部から末端部まで延びる側壁を有し、流体を収容するチャンバを定義するバレル、
前記バレルの前記末端部に配置されたシリンジ先端であって、前記流体は前記シリンジ先端を通って前記バレルを出る、シリンジ先端、および
前記チャンバの前記末端部に近接して前記チャンバ内に構成された洗浄機構、を備え、
前記洗浄機構が、前記チャンバから前記洗浄機構を介して前記シリンジ先端を出る流体の流れにパルス状の流れを生成している、洗浄シリンジ。 - 前記洗浄機構が:
前記チャンバからの流体の流れにおける回転速度成分のために回転するように構成され、前記チャンバから前記シリンジ先端を出る流体の流れを周期的に塞ぎおよび塞がないように構成されたホイールを備える、請求項1に記載の洗浄シリンジ。 - 前記ホイールが、前記流体の流れの前記回転速度成分を誘発する傾斜した羽根を備える、請求項2に記載の洗浄シリンジ。
- 前記流体の流れに関して前記洗浄機構の上流側に配置されたプレートをさらに備え、前記プレートは、前記流体の流れの方向に関して非ゼロの角度で傾斜した壁を有する少なくとも1つの開口部を備え、前記流体の流れの中に回転速度成分を誘発する、請求項1または2の洗浄シリンジ。
- 前記ホイールの下流側に配置されていてそこに前記ホイールを収容するオリフィスプレートをさらに備える、請求項2、3、または4に記載の洗浄シリンジ。
- 前記オリフィスプレートが、前記バレル内で軸方向に回転可能に固定されている、請求項5に記載の洗浄シリンジ。
- 前記プレートが、前記バレル内で軸方向に回転可能に固定されている、請求項4、5または6に記載の洗浄シリンジ。
- 前記洗浄機構が、前記流体の流れの速度の範囲にわたって共振する前記流体の流れの中に配置された可撓性部材を備える、請求項1に記載の洗浄シリンジ。
- 前記可撓性部材が、内部スリットを備えた壁を有していて、少なくとも部分的に前記シリンジ先端内に配置されている平らなチューブを備え、
前記内部スリットを通過する前記流体の流れが、前記パルス状の流れを作り出す壁の互いの共鳴を引き起こす、請求項8に記載の洗浄シリンジ。 - 前記可撓性部材が、前記シリンジ先端内に少なくとも部分的に配置された中空チューブを備え、
チューブを通過する前記流体の流れが、前記チューブ上で圧縮跳ね返り力を引き起こすことによって、前記チューブが不安定になり、周期的にキンクして前記パルス状の流れを生成する、請求項8に記載の洗浄シリンジ。 - 前記可撓性部材が、
前記シリンジ先端内に少なくとも部分的に配置されたリボン;および
前記流体の流れを前記チャンバから前記リボンの上に案内する支持構造体、を備え、
前記リボンの上を通過する前記流体の流れにより、前記リボンが前記シリンジ先端を通る流れを周期的に乱して前記パルス状の流れを生成することを引き起こす、請求項8に記載の洗浄シリンジ。 - 前記リボンと前記支持構造体が一体的に形成されている、請求項11に記載の洗浄シリンジ。
- 前記支持構造体が、前記流体の流れのための少なくとも1つの開口部を備える、請求項11または12に記載の洗浄シリンジ。
- 前記支持構造体が、前記バレル内で軸方向および回転方向に固定されている、請求項11、12または13に記載の洗浄シリンジ。
- 前記洗浄機構が、前記バレル内で軸方向に回転可能に固定されている、請求項8、9、または10に記載の洗浄シリンジ。
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US201862622907P | 2018-01-28 | 2018-01-28 | |
US62/622,907 | 2018-01-28 | ||
PCT/US2019/015208 WO2019147977A1 (en) | 2018-01-28 | 2019-01-25 | Pulsatile or resonating flush syringe |
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CN113857164B (zh) * | 2021-09-29 | 2022-07-29 | 天津市中西医结合医院(天津市南开医院) | 一种脉冲式自动冲洗中心静脉导管的装置及其清洗方法 |
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EP0627231A2 (en) * | 1993-05-05 | 1994-12-07 | Alza Corporation | Delivery devices with pulsatile effect |
US20020007143A1 (en) * | 2000-06-21 | 2002-01-17 | Medjet, Inc. | Method and process for generating a high repetition rate pulsed microjet |
US20150320937A1 (en) * | 2009-07-10 | 2015-11-12 | Becton, Dickinson And Company | Flush Syringe Assembly With Controlled Pulsatile Flushing |
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US20020116021A1 (en) | 2000-06-21 | 2002-08-22 | Medjet Inc. | Method and process for generating a high repetition rate pulsed microjet |
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- 2019-01-25 CN CN202311020233.3A patent/CN116850379A/zh active Pending
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- 2019-01-25 WO PCT/US2019/015208 patent/WO2019147977A1/en active Application Filing
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JP7366909B2 (ja) | 2023-10-23 |
CN111629770A (zh) | 2020-09-04 |
US11951288B2 (en) | 2024-04-09 |
US20210113772A1 (en) | 2021-04-22 |
CA3088196A1 (en) | 2019-08-01 |
EP3743138A4 (en) | 2021-10-20 |
WO2019147977A1 (en) | 2019-08-01 |
EP3743138A1 (en) | 2020-12-02 |
CN111629770B (zh) | 2023-09-01 |
CN116850379A (zh) | 2023-10-10 |
JP2023171570A (ja) | 2023-12-01 |
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