JP2021505611A5 - - Google Patents

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Publication number
JP2021505611A5
JP2021505611A5 JP2020531104A JP2020531104A JP2021505611A5 JP 2021505611 A5 JP2021505611 A5 JP 2021505611A5 JP 2020531104 A JP2020531104 A JP 2020531104A JP 2020531104 A JP2020531104 A JP 2020531104A JP 2021505611 A5 JP2021505611 A5 JP 2021505611A5
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JP
Japan
Prior art keywords
inhibitor
ikk
pharmaceutical
treatment
subject
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JP2020531104A
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English (en)
Japanese (ja)
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JP2021505611A (ja
JP7527639B2 (ja
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Priority claimed from EP17205864.6A external-priority patent/EP3494994A1/en
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Publication of JP2021505611A5 publication Critical patent/JP2021505611A5/ja
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Publication of JP7527639B2 publication Critical patent/JP7527639B2/ja
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JP2020531104A 2017-12-07 2018-12-07 免疫疾患の予防または治療のためのripk1阻害剤とikk阻害剤の組み合わせ Active JP7527639B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP17205864.6 2017-12-07
EP17205864.6A EP3494994A1 (en) 2017-12-07 2017-12-07 Combinations of ripk1- and ikk-inhibitors for the prevention or treatment of immune diseases
PCT/EP2018/084055 WO2019110832A1 (en) 2017-12-07 2018-12-07 Combinations of ripk1- and ikk-inhibitors for the prevention or treatment of immune diseases

Publications (3)

Publication Number Publication Date
JP2021505611A JP2021505611A (ja) 2021-02-18
JP2021505611A5 true JP2021505611A5 (https=) 2022-01-11
JP7527639B2 JP7527639B2 (ja) 2024-08-05

Family

ID=60629504

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020531104A Active JP7527639B2 (ja) 2017-12-07 2018-12-07 免疫疾患の予防または治療のためのripk1阻害剤とikk阻害剤の組み合わせ

Country Status (7)

Country Link
US (1) US20200383995A1 (https=)
EP (2) EP3494994A1 (https=)
JP (1) JP7527639B2 (https=)
CN (1) CN111670049A (https=)
CA (1) CA3103847A1 (https=)
MX (1) MX2020007036A (https=)
WO (1) WO2019110832A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2021046515A1 (en) * 2019-09-06 2021-03-11 Board Of Regents, The University Of Texas System Inhibitors of receptor interacting protein kinase i for the treatment of disease
IL291665B2 (en) 2019-09-27 2025-07-01 Univ Texas Inhibitors of receptor interacting protein kinase i for the treatment of disease
BR112022010082A2 (pt) 2019-11-26 2022-08-30 Univ Texas Composto de fórmula estrutural i ou sal do mesmo, composição farmacêutica, uso do composto e uso da composição farmacêutica
EP4209213A1 (en) * 2022-01-05 2023-07-12 Universität zu Köln Signalling-pathway inhibitor combinations for use in the treatment of cancer diseases
EP4665334A1 (en) 2023-02-17 2025-12-24 Universität zu Köln Triple kinase inhibition for the treatment of type i interferon response associated disorders
CN119064582B (zh) * 2024-09-02 2025-05-27 南方医科大学南方医院 RIPK1 O-GlcNAc糖基化抑制剂在制备增强肾细胞癌舒尼替尼敏感性药物中的应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL364111A1 (en) * 2001-02-01 2004-12-13 Bristol-Myers Squibb Company Methods of treating inflammatory and immune diseases using inhibitors of ikappab kinase (ikk)
CA2653654A1 (en) * 2006-06-06 2007-12-21 Boehringer Ingelheim International Gmbh Substituted 3-amino-thieno[2,3-b] pyridine-2-carboxamide compounds, their preparation and use
ES2555160B1 (es) * 2014-06-24 2016-10-25 Aptus Biotech, S.L. Aptámeros específicos de TLR-4 y usos de los mismos
EP3017825A1 (en) * 2014-11-06 2016-05-11 Ludwig-Maximilians-Universität München An inhibitor of the RIPK1-dependent necrosis pathway and a pharmaceutical composition comprising the same

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