JP2021145828A - Infusion bag housing exterior bag - Google Patents

Abstract

To provide an infusion bag housing exterior bag which comprises, in addition to light exclusion property, pin hole resistance, gas barrier property, inspection aptitude by a metal detector, and laminate strength of a laminate.SOLUTION: An infusion bag housing exterior bag 10 is formed of a laminate, the laminate is formed by laminating, from an external part of the infusion bag housing exterior bag, a base material film with a light exclusion layer, a gas barrier film, and a sealant film. The gas barrier film has, on a plastic film, a deposition layer of a metal oxide or a silicon oxide, as a gas barrier layer. The sealant film is formed of a biaxial drawing polyolefin based resin. The base material film, the gas barrier film, and the sealant film are laminated through a molten extrusion layer, and between the gas barrier layer of the gas barrier film and the molten extrusion layer, an adhesion assisting layer including polyester and a polyvalent metal oxide, is arranged.SELECTED DRAWING: Figure 1

Description

The present invention relates to a light-shielding bag. In particular, the present invention relates to an infusion bag for infusion, or an infusion bag storage outer bag that can store and seal an infusion container used in medical institutions and the like.

Infusion bags or infusion containers used in medical institutions may need to be stored in a shaded environment. In addition, shading may be required when administering the content solution.

For example, it is necessary to prevent the photodegradation of vitamins by ultraviolet light, or to block light from the infusion bag or infusion container, and if necessary, the entire infusion route when storing or administering a drug that is unstable to light. become.

In such a case, it is used as an outer layer bag for the infusion bag or the infusion container by covering it with an infusion bag storage outer bag having a light-shielding property.

Furthermore, for the infusion bag storage outer bag, not only the light-shielding property, but also the pinhole resistance against pinholes that may occur during transportation, the gas barrier property that blocks the influence of environmental conditions on the contents, and the sterility inside the package. Maintenance of sexuality, etc. is required.

It is effective to use an aluminum-deposited film that also has a light-shielding property to impart gas barrier properties, but on the other hand, when inspecting metal foreign substances that are fatal defects in pharmaceutical packaging materials, inspection with a metal detector is performed. It can be difficult.

Alternatively, as a method for imparting gas barrier properties, it is effective to use a gas barrier film on which an inorganic compound such as a metal oxide or a silicon oxide is vapor-deposited, but a gas barrier layer and a laminate constituting a light-shielding infusion outer bag are formed. There is a risk that the adhesion strength with the molten resin layer will not be sufficient.

On the other hand, Patent Document 1 describes "a packaging material and an infusion solution using the same", which comprises laminating a stretched polypropylene film layer, a stretched ethylene-vinyl alcohol copolymer film layer on which aluminum is vapor-deposited, and an unstretched polyolefin layer. Although a "bag outer bag" has been proposed, although it is effective in light-shielding properties, it may be difficult to inspect metal foreign substances by a metal detector as described above.

Japanese Unexamined Patent Publication No. 2006-193196

The present invention has been made in view of such a situation, and provides an infusion bag storage outer bag having pinhole resistance, gas barrier property, inspection suitability by a metal detector, and laminate strength of a laminate in addition to light shielding property. The task is to do.

The invention according to claim 1 is a means for solving the above problems.
An infusion bag storage outer bag that can be sealed by storing the infusion bag inside.
The infusion bag storage outer bag is composed of a laminated body.
The laminate consists of a base film with a light-shielding layer, a gas barrier film, and a sealant film laminated from the outside of the infusion bag storage outer bag.
The base film with a light-shielding layer uses a plastic film as a base material and has a light-shielding layer provided on the surface.
The gas barrier film is provided with a metal oxide or silicon oxide vapor deposition layer as a gas barrier layer on the surface of the plastic film.
The sealant film is made of a biaxially stretched polyolefin resin.
Each film is laminated via a melt extruded layer.
The infusion bag storage outer bag is characterized by having an adhesive auxiliary layer containing polyester and a polyvalent metal compound between the gas barrier layer and the melt extruded layer of the gas barrier film.

Further, the invention according to claim 2 is
The plastic film of the gas barrier film is a polyethylene terephthalate film.
The infusion bag storage outer bag according to claim 1, wherein the amount of oxygen permeated as the gas barrier film is 1.0 cc / m ^{2, day, atm or less.}

Further, the invention according to claim 3 is
In the base film with a light-shielding layer, the base film is made of a biaxially stretched polyolefin-based film.
Light-shielding layer to the substrate film, the black ink is characterized in that one formed by coating ^{2.7g / m 2 ~5.3g / m 2} , according to claim 1 or claim 2 Infusion bag storage exterior bag.

Further, the invention according to claim 4 is
The infusion bag storage outer bag according to any one of claims 1 to 3, wherein the sealant film has a heat-sealing layer in addition to the biaxially stretched polyolefin-based copolymer film.

Further, the invention according to claim 5 is
The sealant film is a biaxially stretched polyolefin-based copolymer film having a density in the range of ^{915 kg / m 3 to} 938 kg / m ^3.
Heat of fusion obtained by differential scanning calorimeter ([Delta] H _T) is in 100J / g~140J / g, range,
_{The amount of heat of melting (ΔHL) in} the range of 110 ° C. from the melting start temperature is in the range of 50 J / g to 80 J / g.
_{The amount of heat of melting (ΔH H) in} the range of 110 ° C. to the end temperature of melting is in the range of 35 J / g to 80 J / g.
The infusion bag storage outer bag according to any one of claims 1 to 4, wherein the infusion bag storage outer bag is made of a polyolefin-based copolymer in the range of ΔH _H / ΔH _{L = 0.5 to 1.5.} ..

According to the present invention, it is possible to provide an infusion bag storage outer bag having pinhole resistance, gas barrier property, inspection suitability by a metal detector, and lamination strength of a laminate in addition to light shielding property.

That is, the laminate constituting the infusion bag storage outer bag is formed by laminating a base film with a light-shielding layer, a gas barrier film, and a sealant film from the outside of the infusion bag storage outer bag, so that the infusion bag storage outer bag has a light-shielding property. The infusion bag and the contents liquid can be protected from external light rays, and deterioration and deterioration can be prevented.

Since the base film with a light-shielding layer is contained in the laminate, the light-shielding layer blocks light rays from the outside of the infusion bag storage outer bag, and protects the infusion bag and its contents stored inside from the light rays. , It is effective in preventing deterioration and deterioration of the content liquid.

Further, since the gas barrier film is provided with a metal oxide or silicon oxide vapor deposition layer as the gas barrier layer on the plastic film instead of the metal foil or metal vapor deposition film, the metal without sacrificing the gas barrier performance. It can be equipped with inspection suitability by a detector.

Further, since the sealant film is a biaxially stretched polyolefin resin, it is effective in preventing the occurrence of pinholes during transportation.

Each film is laminated via a melt-extruded layer, and is laminated by having an adhesion auxiliary layer containing polyester and a polyvalent metal compound between the gas barrier layer and the melt-extruded layer of the gas barrier film. It is possible to improve the laminating strength of the body. This is effective in preventing bag breakage due to external force.

In particular, according to the invention of claim 2, the base film of the gas barrier film is a polyethylene terephthalate film, and the oxygen permeation amount of the gas barrier film including the gas barrier layer is 1.0 cc / m ² · day · atm. By the following, it is effective to protect the contents of the infusion bag from the influence of the external environment, prevent deterioration and deterioration, and improve the storage stability.

Further, the polyethylene terephthalate film is a general-purpose plastic film, which is easily available and stable in price, and is also suitable for processes such as vacuum deposition, which is advantageous in terms of productivity.

In particular, according to the invention of claim 3, in the base film with a light-shielding layer, the base film is made of a biaxially stretched polyolefin-based film, and the light-shielding layer is the base film with black ink of 2.7 g / m. ^{Since the} film is formed by applying 2 to 5.3 g / m ² , the light-shielding layer can be formed more easily, and the base film with a light-shielding layer having more excellent light-shielding property can be obtained. It is possible.

Generally, the ink can be applied by using a known coating method or printing method, and it is possible to form a light-shielding layer more easily and stably.

Further, according to the invention of claim 4, the sealant film particularly uses a biaxially stretched polyolefin-based copolymer film by having a heat-sealing layer in addition to the biaxially stretched polyolefin-based copolymer film. In some cases, it is effective in preventing bag breakage due to external force and pinholes due to transportation, and by having a heat-sealing layer, it is possible to obtain a laminate with better heat-sealing properties. be.

Further, in particular, according to the invention described in claim 5, the sealant film is a biaxially stretched polyolefin-based copolymer film having a density in ^{the range of 915 kg / m 3 to} 938 kg / m ³ , and has a differential thermal scanning calorific value. range heat of fusion obtained by meter ([Delta] H _T) is in the range of 100J / g~140J / g,, heat of fusion in the range of 110 ° C. from the melting start temperature ([Delta] H _L) is 50J / g~80J / g, the _{The amount of heat of melting (ΔH H) in} the range of 110 ° C. to the end temperature of melting is in the range of 35 J / g to 80 J / g, and ΔH _H / ΔH _L = 0.5 to 1.5. By being made of a based copolymer, it is possible to obtain a laminate with better heat sealing properties, which is effective not only by stabilizing the bag making process but also by preventing bag breakage due to external force and pinholes due to transportation. Is the target.

FIG. 1 is a planar (partially perspective) schematic view for explaining an embodiment of an infusion bag storage outer bag according to the present invention. FIG. 2 is a schematic partial cross-sectional view for explaining one embodiment, examples, and comparative examples of the laminate constituting the infusion bag storage outer bag according to the present invention.

Hereinafter, the present invention will be described in more detail with reference to FIGS. 1 and 2. However, the present invention is not limited to the examples shown here. The present invention is specified by the claims.

FIG. 1 is a planar (partially perspective) schematic view for explaining an embodiment of an infusion bag storage outer bag according to the present invention.

The infusion bag storage outer bag (10) can store the infusion bag (4) inside, and in the example shown in FIG. 1, the rectangular four sides of the infusion bag storage outer bag (10) are sealed (2). ) Is sealed. That is, it has a function of wrapping the infusion bag (4) filled with the content liquid (5) from the outside, sealing it, and protecting it.

The infusion bag storage outer bag (10), which has the infusion bag (4) inside and is sealed, keeps the infusion bag (4) in a hygienic state by blocking foreign substances such as dust and germs. It can be kept and stored for use in medical settings.

Further, the infusion bag storage outer bag (10) according to the present invention is made of a laminate based on a plastic film, and the laminate is provided with a light-shielding layer from the outside of the infusion bag storage outer bag (10). It is composed of a laminate in which a base film, a gas barrier film, and a sealant film are laminated.

Therefore, the light-shielding layer provided on the base film with the light-shielding layer blocks external ultraviolet light and visible light, and the influence of these light rays on the infusion bag (4) and the content liquid (5) thereof. By preventing it, for example, it is possible to prevent deterioration or deterioration of the content liquid (5).

Further, by providing the gas barrier layer on the infusion bag storage outer bag (10), the influence of the external environment, for example, the infiltration of water vapor, oxygen, etc. into the infusion bag (4) is prevented, and the content liquid (5) is prevented. It is possible to prevent deterioration and deterioration of the product.

Further, for example, a metal foil such as aluminum or a vapor deposition layer of metal such as aluminum is also effective as a gas barrier layer, but since it becomes difficult to inspect metal foreign matter by a metal detector, the infusion bag storage outer bag (10) according to the present invention. ) Is inappropriate.

In the example shown in FIG. 1, when using the infusion bag (4), for example, the cut line (3) for opening is torn and opened, and the infusion bag (1) portion is infused from the outside. It is also possible to hang the infusion bag (4) and the infusion bag storage outer bag (10) with the hanging holes (6) and use them for infusion. ..

FIG. 2 is a schematic partial cross-sectional view for explaining one embodiment of the laminate constituting the infusion bag storage outer bag according to the present invention.

As described above, the present invention relates to the infusion bag storage outer bag (10), and the infusion bag storage outer bag (10) is made of a laminate (100) based on a plastic film. .. In the example shown in FIG. 2, the upper part of the figure is the outside of the infusion bag storage outer bag (10).

That is, the laminate (100) is a laminate (100) in which a base film (20) with a light-shielding layer, a gas barrier film (21), and a sealant film (22) are laminated from the outside of the infusion bag storage outer bag (10). ) Consists of.

Of these, the base film (20) with a light-shielding layer is a base film (11) provided with a light-shielding layer (12) on the surface of the plastic film.

Further, the gas barrier film (21) is provided with a gas barrier layer (15) on the surface of the plastic film (16), and the gas barrier layer (15) is formed by a vapor-deposited layer of a metal oxide or a silicon oxide. It is a thing.

As the plastic film (16) of the gas barrier film (21), for example, a polyethylene terephthalate film can be used among the plastic films, and in this case, the gas barrier film (15) is provided with toughness, and the gas barrier layer (15) is formed of the plastic film (16). It has processing suitability when it is provided by vapor deposition on the surface, and is also advantageous in terms of price.

Further, the oxygen permeation amount of the gas barrier film (21) can be 1.0 cc / m ² , day, atm or less, and this gas barrier property is mainly a gas barrier due to a vapor deposition layer of a metal oxide or a silicon oxide. The layer (15) protects the infusion bag (4) and its contents (5) stored inside the infusion bag storage outer bag (10) from deterioration and deterioration due to the influence of the external environment. Will be possible.

For example, silica can be used as the silicon oxide. Further, for example, aluminum oxide can be used as the metal oxide.

The sealant film (22) is made of a plastic film made of a biaxially stretched polyolefin resin, and the sealant films (22) of the laminate (100) are overlapped with each other and sealed to seal the sealant film (22). ) Can be made or sealed. The seal can be, for example, a heat seal that applies heat and pressure.

Further, the sealant film (22) can also have a heat-sealing layer in addition to, for example, a biaxially stretched polyolefin-based copolymer film. It is effective in providing an infusion bag storage outer bag (10) having both pinhole properties and lamination strength.

Of the thermoplastic resins, polyolefin resins are generally used as the material of the sealant film. Specifically, low-density polyethylene resin (LDPE), medium-density polyethylene resin (MDPE), and linear low-density polyethylene resin. (LLDPE), ethylene-vinyl acetate copolymer (EVA), ethylene-α-olefin copolymer, ethylene-methacrylic acid resin copolymer and other ethylene-based resins, polyethylene-polybutene blend resin, homopolypropylene resin Polypropylene-based resins such as (PP), propylene-ethylene random copolymer, propylene-ethylene block copolymer, and propylene-α-olefin copolymer can be used.

Also, sealant film (22), the double of the biaxially stretched polyolefin copolymer films, especially the density is in the range of ^{915kg / m 3 ~938kg / m 3} , the heat of fusion obtained by differential scanning calorimeter ([Delta] H _T ) is in the range of 100 J / g to 140 J / g, and the heat of fusion ( _{ΔHL) in} the range of 110 ° C from the melting start temperature is in the range of 50 J / g to 80 J / g, and the melting ends from 110 ° C. A polyolefin-based copolymer having a heat of fusion (ΔH _{H) in the} temperature range of 35 J / g to 80 J / g and a range of ΔH _H / ΔH _L = 0.5 to 1.5 can be used. can.

In this case, as a sealant film (22) having excellent heat-sealing properties, it is effective to provide an infusion bag storage outer bag (10) having both pinhole resistance and laminating strength.

In the laminated body (100) constituting the infusion bag storage outer bag (10) according to the present invention, the base film (20) with a light-shielding layer and the gas barrier film (21) are laminated via the melt-extruded layer (13). There is.

Further, the gas barrier film (21) and the sealant film (22) are laminated via the melt extrusion layer (17). For this lamination, for example, a method such as forming a film of a resin melted by extrusion with a T-die on a film and laminating different materials can be taken.

The melt-extruded layer (13) and the melt-extruded layer (17) are, for example, high-density polyethylene resin (HDPE), medium-density polyethylene resin (MDPE), low-density polyethylene resin (LDPE), linear low-density polyethylene resin ( LLDPE) and the like can be used. In particular, from the viewpoint of processability, low-density polyethylene resin (LDPE) can be more preferably used.

Further, an adhesion auxiliary layer (14) containing polyester and a polyvalent metal compound is provided between the gas barrier layer (15) and the melt-extruded layer (13) of the gas barrier film (21). For example, zinc oxide (ZnO) can be used as the polyvalent metal compound to form a coat layer containing a polyester resin.

In the process of studying the present invention, the adhesive auxiliary layer (14) is effective in improving the lamination strength between the gas barrier film (21) and the base film (11), and the entire laminate (100) is as a whole. It has been found that the laminate strength can be improved.

In particular, as a result of being effective in improving the adhesive strength between the gas barrier layer (15) and the melt extruded layer (13), it contributes to the improvement of the laminated strength of the entire laminated body (100).

That is, the improvement of the interlayer strength of the laminate (100) constituting the infusion bag storage outer bag (10) is to prevent the infusion bag storage outer bag (10) from being broken by an external force and the occurrence of pinholes due to transportation. It is effective.

The base film (20) with a light-shielding layer is obtained by providing a light-shielding layer (12) on the surface of a plastic film which is a base film (11). For example, the base film (11) is a biaxially stretched polyolefin. It can be a system film.

Further, the light-shielding layer (12) can be provided on the base film (11) by printing or by a method using a coating. For example, the black ink is applied to the base film (11) at 2.7 g / m ^{2 to} 5. It can be formed by coating in the range of .3 g / m ^2.

For example, as the black ink forming the light-shielding layer (12), an ink made by adding carbon black to urethane resin can be used, and the OD value of the light-shielding layer is set to 3.4 or more depending on the above-mentioned coating amount. Is possible.

In this case, a light-shielding layer having more excellent light-shielding property can be obtained, and the infusion bag (4) and the content liquid (5) stored inside the infusion bag storage outer bag (10) can be used in the external environment, especially. It is possible to protect from deterioration and deterioration due to the influence of ultraviolet light and visible light.

When the light-shielding layer (12) is provided by a printing method or a coating method, the productivity is more excellent, and the light-shielding layer (12) can be uniformly and accurately provided on the base film (11). It is possible.

Here, the printing method and the coating method as the coating device are not particularly limited, but they are appropriately selected from the known printing methods or coating methods in consideration of the printability on the plastic film. Can be done.

Regarding inks and paints, in addition to compatibility with the coating device, the light-shielding property when the light-shielding layer (12) is formed on the base film (11), and the coating amount for achieving the light-shielding property are taken into consideration. It may be selected as appropriate.

For example, in the case of a printing method, it can be selected from known printing methods such as a gravure printing method, an offset printing method, a gravure offset printing method, a flexo printing method, a silk screen printing method, and an inkjet printing method. Among them, the gravure printing method can be preferably used in terms of productivity, printability on a plastic film, and high definition of a pattern.

Further, in the case of the coating method, known devices such as a roll coater, a die coater, and a lip coater can be used.

In the present invention, a plastic film is used as the base film for the base film (20) with a light-shielding layer and the gas barrier film (21) contained in the laminate (100).

The plastic film is a film made of a polymer resin composition, for example, polyolefin (polyethylene, polypropylene, etc.), polyester (polyethylene terephthalate, polybutylene terephthalate, polyethylene naphthalate, etc.), polyamide (nylon-6, nylon-66, etc.), etc. ), Polyethylene, etc. can be used and are appropriately selected according to the application and purpose.

Of these, when polypropylene or polyethylene terephthalate is used as the plastic film, it is more preferable in terms of film strength and price. In particular, when a stretched polypropylene film is used, it is preferable from the viewpoint of improving pinhole resistance. In addition, when a stretched polyamide film is used, it is possible to impart toughness against piercing and impact resistance to the laminated body.

In the case of the gas barrier film (21), the gas barrier layer (15) can be composed of a vapor deposition layer and a coating layer of an inorganic compound. After providing an anchor coat on the plastic film (16), a vapor deposition layer is provided, if necessary. Further, a coating layer is provided in sequence.

For example, urethane acrylate can be used for the anchor coat layer of the gas barrier film. For the formation of the anchor coat layer, a coating method in which a coating material in which a resin is dissolved in a solvent is applied by a printing method such as gravure coating can be used, or a coating film can be formed by using a generally known coating method.

As a method for forming the vapor deposition layer, for example, an inorganic compound such as silica or aluminum oxide is coated on a plastic film provided with an anchor coat layer by a vacuum vapor deposition method to form an inorganic compound layer by the vacuum vapor deposition method. Can be done. The thickness of the thin-film deposition layer is preferably 15 nm to 30 nm.

As a method for forming the coating layer, an aqueous solution containing at least one of a water-soluble polymer, (a) one or more metal alkoxides or a hydrolyzate thereof, or both, or (b) tin chloride, or water. / A coating agent containing an alcohol mixed aqueous solution as a main component can be applied onto a film and dried by heating to form an inorganic compound layer by a coating method to form a coating layer. At this time, by adding a silane monomer to the coating agent, it is possible to improve the adhesion with the anchor coat layer.

The inorganic compound layer has a gas barrier property only by the coating film by the vacuum vapor deposition method, but the coating layer which is the inorganic compound layer by the coating method is formed by superimposing on the vapor deposition layer which is the inorganic compound layer by the vacuum vapor deposition method to form a gas barrier layer. be able to.

By combining these two layers, a reaction layer of both layers is formed at the interface between the inorganic compound layer by the vacuum vapor deposition method and the inorganic compound layer by the coating method, or the inorganic compound layer by the coating method becomes an inorganic compound layer by the vacuum vapor deposition method. A dense structure is formed by filling and reinforcing defects or micropores such as pinholes, cracks, and grain boundaries that occur.

Therefore, the gas barrier film has higher gas barrier properties, moisture resistance, and water resistance, and has flexibility to withstand deformation due to an external force, so that it can be suitable as a packaging material.

In this way, according to the present invention, there is provided an infusion bag storage outer bag (10) having pinhole resistance, gas barrier property, inspection suitability by a metal detector, and lamination strength of a laminate in addition to light shielding property. It is possible.

If necessary, a printing layer is provided on the layer that can be seen from the outside in the laminate based on the plastic film for the purpose of improving the image as a product, displaying necessary information about the contents, and improving the design. be able to. The printing layer may be provided on the outermost layer of the infusion bag storage outer bag.

Further, the print layer may be provided on a part thereof or may be provided over the entire surface. Alternatively, as a method of providing the display unit without using the printing layer, for example, a printed sticker can be attached to the surface.

Here, the printing method and the printing ink are not particularly limited, but from among the known printing methods, printability on a plastic film, design such as color tone, adhesion, safety as a container, etc. If the above is taken into consideration, it may be appropriately selected.

For example, it can be selected from known printing methods such as a gravure printing method, an offset printing method, a gravure offset printing method, a flexo printing method, a silk screen printing method, and an inkjet printing method. Among them, the gravure printing method can be preferably used in terms of productivity, printability on a plastic film, and high definition of a pattern.

Hereinafter, the present invention will be described in more detail with reference to Examples and Comparative Examples. However, the present invention is not limited to the examples shown here. The present invention is specified by the claims. In the following comparative example, a portion deviating from the embodiment of the present invention is shown.

An evaluation sample of the infusion bag storage outer bag (10) was prepared and evaluated.
The evaluation items and evaluation criteria are as follows.

-Light-shielding property: The optical density OD value was measured.
A 361T desktop densitometer manufactured by X-Rite Co., Ltd. was used as the measuring instrument.
Evaluation criteria: An OD value of 3.40 or higher was considered acceptable.

-Laminate strength: The laminate strength between the base film and the gas barrier film was measured.
The measurement was carried out by cutting the sample into a width of 15 mm, peeling angle 180 degrees, and a speed of 300 mm / min.
As a measuring instrument, RTF-1250 manufactured by A & D Co., Ltd. was used.
Evaluation criteria: Peeling strength of 1.0 N / 15 mm or more was regarded as acceptable.

-Gas barrier property: Oxygen permeability was measured under a 30 ° C. and 70% RH environment. Measurement is JIS
This was done based on K 7126-2.
The measuring instrument used was OXTRAN manufactured by Mocon.
Evaluation criteria: 1.0 cc / m ² , day, atm or less was regarded as acceptable.

-Transportation test: The state of transportation was reproduced, and the number of pinholes that occurred in the infusion bag storage outer bag was counted.
A plastic infusion bag was filled with 1000 ml of the content liquid, placed in an infusion bag storage outer bag (300 mm × 340 mm three-way bag), sealed, and vibrated in the Z-axis direction at an acceleration of 3 G for 60 minutes.
Evaluation criteria: The number of pinholes generated was 0.

Those who passed all the evaluation items of these four items were evaluated as comprehensive judgment 〇.

In the description of Examples and Comparative Examples, a schematic partial cross-sectional view for explaining one embodiment and Examples and Comparative Examples of the laminate constituting the infusion bag storage outer bag according to the present invention shown in FIG. Shall refer to.

<Example 1>
The material composition of the laminated body (100) is as follows.
Infusion bag storage From the outside of the outer bag
-Base film (11): Stretched polypropylene film (OPP) Futamura Chemical Co., Ltd. F
OS thickness 50 μm
-Light-shielding layer (12): Polyurethane resin + carbon black N800LPGT manufactured by Toyo Ink Mfg. Co., Ltd.
Ink application amount 2.7 g / m ²
-Melted extruded layer (13): Low density polyethylene resin (LDPE) LC600A manufactured by Japan Polyethylene Corporation Thickness 15 μm
-Adhesion auxiliary layer (14): Polyvalent metal compound (ZnO) + polyester resin Toppan Printing-Gas barrier film (21): Metal oxide-deposited polyethylene terephthalate film Toppan Printing 12 μm thick
-Melted extruded layer (17): Low density polyethylene resin (LDPE) LC600A manufactured by Japan Polyethylene Corporation Thickness 15 μm
-Sealant film (22): Biaxially stretched linear low-density polyethylene (LLDPE) film Mitsui Chemicals Tocello Co., Ltd. L-Smart (registered trademark) C-1 Thickness 50 μm
And said.

<Example 2>
The material composition of the laminated body (100) is as follows.
Infusion bag storage From the outside of the outer bag
-Base film (11): Stretched polypropylene film (OPP) FOS manufactured by Futamura Chemical Co., Ltd. FOS thickness 50 μm
-Light-shielding layer (12): Polyurethane resin + carbon black N800LPGT manufactured by Toyo Ink Mfg. Co., Ltd.
Ink application amount 5.3 g / m ² Only this ink application amount is different from Example 1.
-Melted extruded layer (13): Low density polyethylene resin (LDPE) LC600A manufactured by Japan Polyethylene Corporation Thickness 15 μm
-Adhesion auxiliary layer (14): Polyvalent metal compound (ZnO) + polyester resin Toppan Printing-Gas barrier film (21): Metal oxide-deposited polyethylene terephthalate film Toppan Printing 12 μm thick
-Melted extruded layer (17): Low density polyethylene resin (LDPE) LC600A manufactured by Japan Polyethylene Corporation Thickness 15 μm
-Sealant film (22): Biaxially stretched linear low-density polyethylene (LLDPE) film Mitsui Chemicals Tocello Co., Ltd. L-Smart (registered trademark) C-1 Thickness 50 μm
And said.

<Comparative example 1>
The material composition of the laminated body (100) is as follows.
Infusion bag storage From the outside of the outer bag
-Base film (11): Stretched polypropylene film (OPP) FOS manufactured by Futamura Chemical Co., Ltd. FOS thickness 50 μm
-Light-shielding layer (12): A colored sealant was used. [This part deviates from the scope specified by the present invention. ]
-Melted extruded layer (13): Low density polyethylene resin (LDPE) LC600A manufactured by Japan Polyethylene Corporation Thickness 15 μm
-Adhesion auxiliary layer (14): Polyvalent metal compound (ZnO) + polyester resin Toppan Printing-Gas barrier film (21): Metal oxide-deposited polyethylene terephthalate film Toppan Printing 12 μm thick
-Melted extruded layer (17): Low density polyethylene resin (LDPE) LC600A manufactured by Japan Polyethylene Corporation Thickness 15 μm
-Sealant film (22): Colored sealant LD-BLACK manufactured by Tamapoli Co., Ltd. Thickness 50 μm. [This part deviates from the scope specified by the present invention]
And said.

<Comparative example 2>
The material composition of the laminated body (100) is as follows.
Infusion bag storage From the outside of the outer bag
-Base film (11): Stretched polypropylene film (OPP) FOS manufactured by Futamura Chemical Co., Ltd. FOS thickness 50 μm
-Light-shielding layer: A metal vapor deposition layer was used. [This part deviates from the scope specified by the present invention. ]
-Melted extruded layer (13): Low density polyethylene resin (LDPE) LC600A manufactured by Japan Polyethylene Corporation Thickness 15 μm
-Adhesion auxiliary layer (14): Polyvinyl alcohol resin (PVA) + silane coupling agent Toppan Printing [This part is outside the scope specified by the present invention. ]
-Gas barrier film: Aluminum-deposited polyethylene terephthalate film Made by Toppan Printing Thickness 12 μm [This portion deviates from the range specified in the present invention. ]
-Melted extruded layer (17): Low density polyethylene resin (LDPE) LC600A manufactured by Japan Polyethylene Corporation Thickness 15 μm
-Sealant film (22): Biaxially stretched linear low-density polyethylene (LLDPE) film Mitsui Chemicals Tocello Co., Ltd. L-Smart (registered trademark) C-1 Thickness 50 μm
And said.

<Comparative example 3>
The material composition of the laminate is as follows.
Infusion bag storage From the outside of the outer bag
-Base film (11): Stretched polypropylene film (OPP) FOS manufactured by Futamura Chemical Co., Ltd. FOS thickness 50 μm
-Light-shielding layer (12): Polyurethane resin + carbon black N800LPGT manufactured by Toyo Ink Mfg. Co., Ltd.
Ink application amount 1.3 g / m ² [This portion deviates from the range specified in the present invention. ]
-Melted extruded layer (13): Low density polyethylene resin (LDPE) LC600A manufactured by Japan Polyethylene Corporation Thickness 15 μm
-Adhesion auxiliary layer (14): Polyvalent metal compound (ZnO) + polyester resin Toppan Printing-Gas barrier film (21): Metal oxide-deposited polyethylene terephthalate film Toppan Printing 12 μm thick
-Melted extruded layer (17): Low density polyethylene resin (LDPE) LC600A manufactured by Japan Polyethylene Corporation Thickness 15 μm
-Sealant film (22): Biaxially stretched linear low-density polyethylene (LLDPE) film Mitsui Chemicals Tocello Co., Ltd. L-Smart (registered trademark) C-1 Thickness 50 μm
And said.

<Comparative example 4>
The material composition of the laminated body (100) is as follows.
Infusion bag storage From the outside of the outer bag
-Base film (11): Stretched polypropylene film (OPP) FOS manufactured by Futamura Chemical Co., Ltd. FOS thickness 50 μm
-Light-shielding layer (12): Polyurethane resin + carbon black N800LPGT manufactured by Toyo Ink Mfg. Co., Ltd.
Ink application amount 2.7 g / m ²
-Melted extruded layer (13): Low density polyethylene resin (LDPE) LC600A manufactured by Japan Polyethylene Corporation Thickness 15 μm
-Adhesive auxiliary layer: None [This part deviates from the scope specified by the present invention. ]
-Gas barrier film (21): Metal oxide thin-film polyethylene terephthalate film Toppan Printing 12 μm thick
-Melted extruded layer (17): Low density polyethylene resin (LDPE) LC600A manufactured by Japan Polyethylene Corporation Thickness 15 μm
-Sealant film (22): Biaxially stretched linear low-density polyethylene (LLDPE) film Mitsui Chemicals Tocello Co., Ltd. L-Smart (registered trademark) C-1 Thickness 50 μm
And said.

<Comparative example 5>
The material composition of the laminated body (100) is as follows.
Infusion bag storage From the outside of the outer bag
-Base film (11): Stretched polypropylene film (OPP) FOS manufactured by Futamura Chemical Co., Ltd. FOS thickness 50 μm
-Light-shielding layer (12): Polyurethane resin + carbon black N800LPGT manufactured by Toyo Ink Mfg. Co., Ltd.
Ink application amount 2.7 g / m ²
-Melted extruded layer (13): Low density polyethylene resin (LDPE) LC600A manufactured by Japan Polyethylene Corporation Thickness 15 μm
-Adhesion auxiliary layer (14): Polyvalent metal compound (ZnO) + polyester resin Toppan Printing-Gas barrier film: Polyethylene terephthalate film Thickness 12 μm However, metal oxide vapor deposition is not provided as the gas barrier layer. [This part deviates from the scope specified by the present invention. ]
-Melted extruded layer (17): Low density polyethylene resin (LDPE) LC600A manufactured by Japan Polyethylene Corporation Thickness 15 μm
-Sealant film (22): Biaxially stretched linear low-density polyethylene (LLDPE) film Mitsui Chemicals Tocello Co., Ltd. L-Smart (registered trademark) C-1 Thickness 50 μm
And said.

<Comparative Example 6>
The material composition of the laminated body (100) is as follows.
Infusion bag storage From the outside of the outer bag
-Base film (11): Stretched polypropylene film (OPP) FOS manufactured by Futamura Chemical Co., Ltd. FOS thickness 50 μm
-Light-shielding layer (12): Polyurethane resin + carbon black N800LPGT manufactured by Toyo Ink Mfg. Co., Ltd.
Ink application amount 2.7 g / m ²
-Melted extruded layer (13): Low density polyethylene resin (LDPE) LC600A manufactured by Japan Polyethylene Corporation Thickness 15 μm
-Adhesion auxiliary layer (14): Polyvalent metal compound (ZnO) + polyester resin Toppan Printing-Gas barrier film (21): Metal oxide-deposited polyethylene terephthalate film Toppan Printing 12 μm thick
-Melted extruded layer (17): Low density polyethylene resin (LDPE) LC600A manufactured by Japan Polyethylene Corporation Thickness 15 μm
-Sealant film (22): Non-stretched linear low-density polyethylene (LLDPE) film SE620L manufactured by Tamapoli Co., Ltd. Thickness 60 μm [This portion deviates from the range specified in the present invention. ]
And said.

<Comparative Example 7>
The material composition of the laminated body (100) is as follows.
Infusion bag storage From the outside of the outer bag
-Base film (11): Stretched polypropylene film (OPP) FOS manufactured by Futamura Chemical Co., Ltd. FOS thickness 50 μm
-Light-shielding layer (12): Polyurethane resin + carbon black N800LPGT manufactured by Toyo Ink Mfg. Co., Ltd.
Ink application amount 2.7 g / m ²
-Melted extruded layer (13): Low density polyethylene resin (LDPE) LC600A manufactured by Japan Polyethylene Corporation Thickness 15 μm
-Adhesion auxiliary layer (14): Polyvinyl alcohol resin (PVA) + silane coupling agent Toppan Printing [This part is outside the scope specified by the present invention. ]
-Gas barrier film (21): Metal oxide thin-film polyethylene terephthalate film Toppan Printing 12 μm thick
-Melted extruded layer (17): Low density polyethylene resin (LDPE) LC600A manufactured by Japan Polyethylene Corporation Thickness 15 μm
-Sealant film (22): Biaxially stretched linear low-density polyethylene (LLDPE) film Mitsui Chemicals Tocello Co., Ltd. L-Smart (registered trademark) C-1 Thickness 50 μm
And said.

The evaluation results are shown in Table 1.

As is clear from the results shown in Table 1, in the infusion bag storage outer bag (10) according to the present invention, that is, in Example 1 and Example 2, light-shielding property, peel strength, gas barrier property, transportation test, all items. The evaluation criteria were satisfied in the above, and the overall judgment was 〇 evaluation.

That is, according to the present invention, it is possible to provide an infusion bag storage outer bag having pinhole resistance, gas barrier property, inspection suitability by a metal detector, and laminate strength of a laminate in addition to light shielding property. Is shown.

On the other hand, if a part of the material composition of the laminate constituting the infusion bag storage outer bag deviates from the range specified by the present invention, as shown by the evaluation results of Comparative Examples 1 to 7, the light-shielding property In the items of, peel strength, gas barrier property, and transportation test, all the evaluation criteria could not be satisfied.

Next, the evaluation results of Examples 1 to 2 and Comparative Examples 1 to 7 will be individually considered.

In Example 1, the OD value for evaluating the light-shielding property was 3.69, which exceeded the OD value of 3.4, which was the criterion for determination, and passed. This indicates that the layer made of black ink forming the light-shielding layer (12) is sufficient in terms of its density and coating amount.

Regarding the peel strength, an adhesive auxiliary layer (14) made of a polyvalent metal compound (ZnO) + polyester resin is provided, and sufficient adhesive strength is provided between the melt extruded layer (13) and the gas barrier layer (15). It is an effect that was able to be realized.

The gas barrier properties, relative to 1.0cc ^/ m 2 · day · atm criteria, is acceptable a ^{0.8cc / m 2 · day · atm} . This is due to the effect of the gas barrier film (21) and the gas barrier performance of the metal oxide vapor-deposited film layer.

As for the transportation test, as a result of using biaxially stretched linear low-density polyethylene for the sealant film (22), the occurrence of pinholes could be prevented.

In Example 2, the OD value for evaluating the light-shielding property was 5.59, which greatly exceeded the OD value of 3.4, which was the criterion for determination, and passed the test. This indicates that the layer made of black ink forming the light-shielding layer (12) is sufficient in terms of its density and coating amount.

Regarding the peel strength, an adhesive auxiliary layer (14) made of a polyvalent metal compound (ZnO) + polyester resin is provided as in Example 1, and is provided between the melt extrusion layer (13) and the gas barrier layer (15). This is an effect of achieving sufficient adhesive strength.

The gas barrier properties, relative to 1.0cc ^/ m 2 · day · atm criteria, is acceptable a ^{0.8cc / m 2 · day · atm} . This is the effect of the gas barrier film (21) as in Example 1, and is due to the gas barrier performance of the metal oxide vapor-deposited film layer.

As for the transport test, as a result of using biaxially stretched linear low-density polyethylene for the sealant film (22) as in Example 1, the occurrence of pinholes could be prevented.

As described above, based on the evaluation results of Example 1 and Example 2 according to the present invention, the infusion bag storage having pinhole resistance, gas barrier property, inspection suitability by a metal detector, and laminate strength of the laminate in addition to light shielding property. It can be seen that it is possible to provide the outer bag (10).

Hereinafter, with respect to Comparative Examples 1 to 7, for each evaluation item, consideration will be given to the factors that are below the evaluation criteria and are rejected.

Regarding the light-shielding property, Comparative Example 1 and Comparative Example 3 failed.

Comparative Example 1 is a result of trying to realize light-shielding property by using a colored sealant film instead of providing an ink layer to realize light-shielding property, but sufficient light-shielding property could not be obtained. ..

In Comparative Example 3, although an ink layer was provided to achieve light-shielding property, the coating amount was not sufficient and the light-shielding property was unacceptable.

Thus, when the light-shielding layer provided black ink layer (12), the coating amount has resulted in 2.7g ^{/ m 2} ~5.3g ^/ m 2 is support the more preferable.

Regarding the peel strength, Comparative Example 2, Comparative Example 4, and Comparative Example 7 failed.

Comparative Example 2 is a result that the interlayer strength between the melt-extruded layer (13) and the gas barrier layer (15) could not be reinforced because the polyvinyl alcohol resin was used for the adhesive auxiliary layer (14).

In Comparative Example 4, the adhesive auxiliary layer is not provided. Therefore, it is a result that the interlayer strength between the melt-extruded layer (13) and the gas barrier layer (15) cannot be reinforced.

In Comparative Example 7, since the polyvinyl alcohol resin is used for the adhesion auxiliary layer (14) as in Comparative Example 2, the interlayer strength between the melt extruded layer (13) and the gas barrier layer (15) can be reinforced. This is the result of not being able to do it.

Regarding the gas barrier property, Comparative Example 5 largely exceeded the evaluation standard in terms of oxygen permeability and failed. This is because the laminated body (100) constituting the infusion bag storage outer bag (10) is not provided with the gas barrier layer (15).

Regarding the transportation test, the occurrence of pinholes is seen in 1 in Comparative Example 1 and 2 in Comparative Example 6. It is considered that these are caused by using a non-stretched sealant film instead of a biaxially stretched polyolefin film for the sealant film (22).

Specifically, as shown in the material composition of the laminate, in Comparative Example 1, an unstretched colored sealant film was used, and in Comparative Example 6, an unstretched linear low-density polyethylene film was used.

That is, from the evaluation results of Examples 1 to 2 and Comparative Examples 1 to 7, according to the present invention, in addition to light-shielding property, pinhole resistance, gas barrier property, and inspection suitability by a metal detector , It was possible to verify that it is possible to provide an infusion bag storage outer bag having the laminating strength of the laminated body.

1 ... Mouth plug 2 ... Seal part 3 ... Cut line 4 ... Infusion bag 5 ... Contents liquid 6 ... Hanging hole 10 ... Infusion bag storage Exterior bag 11. .. Base film 12 ... Light-shielding layer 13 ... Melting extrusion layer 14 ... Adhesive auxiliary layer 15 ... Gas barrier layer 16 ... Plastic film 17 ... Melting extrusion layer 20 ... Light-shielding layer With base film 21 ... Gas barrier film 22 ... Sealant film 100 ... Laminated body

Claims (5)

An infusion bag storage outer bag that can be sealed by storing the infusion bag inside.
The infusion bag storage outer bag is composed of a laminated body.
The laminate consists of a base film with a light-shielding layer, a gas barrier film, and a sealant film laminated from the outside of the infusion bag storage outer bag.
The base film with a light-shielding layer uses a plastic film as a base material and has a light-shielding layer provided on the surface.
The gas barrier film is provided with a metal oxide or silicon oxide vapor deposition layer as a gas barrier layer on the surface of the plastic film.
The sealant film is made of a biaxially stretched polyolefin resin.
Each film is laminated via a melt extruded layer.
An infusion bag storage outer bag, characterized in that an adhesive auxiliary layer containing polyester and a polyvalent metal compound is provided between the gas barrier layer and the melt extruded layer of the gas barrier film. The plastic film of the gas barrier film is a polyethylene terephthalate film.
The infusion bag storage outer bag according to claim 1, wherein the amount of oxygen permeated as the gas barrier film is 1.0 cc / m ^{2, day, atm or less.} In the base film with a light-shielding layer, the base film is made of a biaxially stretched polyolefin-based film.
Light-shielding layer to the substrate film, the black ink is characterized in that one formed by coating ^{2.7g / m 2 ~5.3g / m 2} , according to claim 1 or claim 2 Infusion bag storage exterior bag. The infusion bag storage outer bag according to any one of claims 1 to 3, wherein the sealant film has a heat-sealing layer in addition to a biaxially stretched polyolefin-based copolymer film. The sealant film is a biaxially stretched polyolefin-based copolymer film having a density in the range of ^{915 kg / m 3 to} 938 kg / m ^3.
Heat of fusion obtained by differential scanning calorimeter ([Delta] H _T) is in 100J / g~140J / g, range,
_{The amount of heat of melting (ΔHL) in} the range of 110 ° C. from the melting start temperature is in the range of 50 J / g to 80 J / g.
_{The amount of heat of melting (ΔH H) in} the range of 110 ° C. to the end temperature of melting is in the range of 35 J / g to 80 J / g.
The infusion bag storage outer bag according to any one of claims 1 to 4, wherein the infusion bag storage outer bag is made of a polyolefin-based copolymer in the range of ΔH _H / ΔH _{L = 0.5 to 1.5.}

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