JP2021102576A - Oil-in-water emulsified skin cosmetics - Google Patents

Abstract

To provide oil-in-water emulsified skin cosmetics that give a feel of thickness at the time of application while avoiding stickiness, confer freshness to the skin, and prevent unnatural whiteness during the application.SOLUTION: Oil-in-water emulsified skin cosmetics contain (A) an alkylene oxide derivative of 0.1-10 mass%, (B) a C12-22 monohydric alcohol of 0.2-10 mass%, (C) a solid or pasty oil solution with a melting point of 20-90°C, of 1-15 mass%, and (D) a nonionic surfactant having a hydrocarbon group with an HLB of 3-18 and 12-24 carbon atoms or a hydroxy group-containing hydrocarbon group with an HLB of 3-18 and 12-24 carbon atoms, of 0.5-10 mass%. The alkylene oxide derivative is represented by formula (1): Z-[O-(PO)a-(PO)b/(EO)c]-H]n (1).SELECTED DRAWING: Figure 1

Description

The present invention relates to an oil-in-water emulsified skin cosmetic that gives a freshness to the skin and suppresses whitening during application without a sticky feeling while feeling the thickness at the time of application.

When the barrier function and water retention function of the stratum corneum are deteriorated, various skin troubles such as rough skin, disordered texture, dryness, and deterioration of flexibility are caused. For such skin troubles, it is known that emulsified cosmetics are used in which oil forms a film on the skin to suppress water evaporation.

In general, it is important that emulsified cosmetics have a feeling of use that is preferred by consumers. Consumers prefer a feeling of use that is not sticky, has an excellent moisturizing feeling, and has a fresh feeling of use. By blending a specific ester oil and a thickener, an emulsified composition (Patent Document 1) that has good skin compatibility, is fresh and has no stickiness, and is excellent in usability is disclosed.

In recent years, in particular, in order to encourage consumers to continue using the product, there is a demand for a thick feel at the time of application that gives a high-class feeling. Regarding the thickness at the time of application, a method of using an oil-in-water emulsified composition (Patent Document 2) in which a high melting point oil agent and a liquid oil are mixed in combination is disclosed.

Although the oil-in-water emulsified cosmetic prepared by the above method can impart thickness, it may lack freshness. To solve such a problem, an emulsified composition capable of producing freshness while imparting thickness at the time of coating by using a high melting point oil agent and a specific alkylene oxide derivative has been disclosed (Patent Document 3).

Japanese Unexamined Patent Publication No. 2013-53090 Japanese Unexamined Patent Publication No. 2012-214448 Japanese Unexamined Patent Publication No. 2013-189392

However, the oil-in-water emulsified cosmetics using a large amount of high-melting point oils have a problem that whitening occurs during application and unevenness occurs on the skin, although the thickness can be imparted at the time of application.
Therefore, it is required not only to achieve both thickness and freshness at the time of application, but also to improve the feel during application.

An object of the present invention is to provide an oil-in-water emulsified skin cosmetic that gives a freshness to the skin and suppresses whitening during application without a sticky feeling while being felt thick at the time of application.

As a result of repeated studies to solve the above problems, the present inventors have found that the above object can be achieved by combining a specific alkyl oxide derivative and a high melting point oil agent in a specific ratio.

That is, the present invention
(A) 0.1 to 10% by mass of the following alkylene oxide derivative,
(B) 0.2 to 10% by mass of monohydric alcohol having 12 to 22 carbon atoms,
(C) 1 to 15% by mass of a solid or paste-like oil having a melting point of 20 to 90 ° C., and (D) a hydrocarbon group having HLB 3 to 18 and 12 to 24 carbon atoms or HLB 3 to 18 and 12 to 12 carbon atoms. 0.5-10% by mass of nonionic surfactant having 24 hydroxyl group-containing hydrocarbon groups
It relates to an oil-in-water emulsified skin cosmetic, which is characterized by being contained.

(A) The ratio Mz / Mw of the weight average molecular weight (Mw) and the z average molecular weight (Mz) represented by the formula (1) and calculated from the chromatogram obtained by gel permeation chromatography measurement is of the formula (2). An alkylene oxide derivative that satisfies the relationship

Z- [O- (PO) _a- (PO) _b / (EO) _c ] -H] _n ... (1)

(In equation (1),
Z represents a residue obtained by removing all hydroxyl groups from a compound having 1 to 24 carbon atoms and 1 to 6 hydroxyl groups.
n represents a number from 1 to 6
PO indicates an oxypropylene group,
EO indicates an oxyethylene group,
a and b indicate the average number of moles of the oxypropylene group PO added, respectively.
c indicates the average number of moles of the oxyethylene group EO added.
a indicates a number from 0 to 100, b indicates a number from 1 to 100, c indicates 1 to 200, a + b + c ≧ 10 and b / c = 1/5 to 5/1.
(PO) _b / (EO) _c indicates that the oxypropylene group PO and the oxyethylene group EO are randomly added, and the random ratio x of the oxypropylene group PO and the oxyethylene group EO is 0.1. ≦ x ≦ 1. )

5 ≤ M _z / M _w ≤ 60 ... (2)

The oil-in-water emulsified skin cosmetic of the present invention gives the skin freshness and suppresses whitening during application without a sticky feeling while feeling the thickness at the time of application.

FIG. 1 is a model chromatogram diagram for explaining Mz / Mw defined in the present invention.

The oil-in-water emulsified skin cosmetic of the present invention contains the following components (A), (B), (C), and (D). Hereinafter, the component (A), the component (B), the component (C), and the component (D) will be described in order.

[(A) component]
The component (A) used in the present invention is a compound represented by the formula (1), and has a weight average molecular weight (Mw) and a z average molecular weight (Mz) calculated from a chromatogram obtained by gel permeation chromatography measurement. ) Is an alkylene oxide derivative having a ratio of Mz / Mw that satisfies the relationship of the formula (2).

Z- [O- (PO) _a- (PO) _b / (EO) _c ] -H] _n ... (1)

Z has 1 to 24 carbon atoms, preferably 1 to 12 carbon atoms, more preferably 1 to 6 carbon atoms, and all hydroxyl groups from the compound (Z (OH) n) having 1 to 6 hydroxyl groups. The residue is excluded, and n is the number of hydroxyl groups of the compound (Z (OH) n), which is 1 to 6. As the compound having 1 to 6 hydroxyl groups (Z (OH) n), if n = 1, methanol, ethanol, butanol, if n = 2, ethylene glycol, propylene glycol, hexylene glycol, n = 3 for glycerin, trimethylolpropane, n = 4 for erythritol, pentaerythritol, sorbitan, diglycerin, alkylglycoside, n = 5 for xylitol, n = 6 for dipentaerythritol, sorbitol, inositol And so on. Further, a mixture thereof may be used as the compound having 1 to 6 hydroxyl groups. n is preferably 1 to 4, more preferably 1 to 3, and most preferably 1.

In the formula (1), when n = 1, Z is a hydrocarbon group having 1 to 24 carbon atoms. Examples of the hydrocarbon group include an alkyl group, an alkenyl group, a cycloalkyl group, an aryl group, and an aralkyl group. It is preferably an alkyl group or an alkenyl group, more preferably an alkyl group or an alkenyl group having 1 to 12 carbon atoms, more preferably an alkyl group having 1 to 6 carbon atoms, and most preferably an alkyl group having 4 carbon atoms. The alkyl group having 1 to 6 carbon atoms may be linear or branched, but a linear alkyl group is more preferable. Examples of the linear alkyl group having 1 to 6 carbon atoms include a methyl group, an ethyl group, a propyl group, a butyl group, and a hexyl group. The hydrocarbon group having 1 to 24 carbon atoms may be only one type or two or more types.

PO is an oxypropylene group, EO is an oxyethylene group, and a and b are the average number of moles of PO and EO, respectively. a indicates a number from 0 to 100, b indicates a number from 1 to 100, c indicates a number from 1 to 200, and a + b + c ≧ 10.
(PO) _b / (EO) _c indicates a polyoxyalkylene group formed by randomly adding PO and EO, and the molar ratio (b / c) of PO and EO is 1/5 to 5/1, and PO and EO. The random rate x of is 0.1 ≦ x ≦ 1.

If a + b + c is less than 10, the thickness of the oil-in-water skin cosmetic when applied may be insufficient. From this point of view, a + b + c is set to 10 or more, more preferably 15 or more, and most preferably 50 or more. In addition, the viscosity increases as a + b + c increases. From the viewpoint of ease of dispersion and compounding, a + b + c is preferably 150 or less, more preferably 120 or less, and most preferably 70 or less. The total average addition mole number n × (a + b + c) of PO and EO is preferably 30 or more, more preferably 40 or more, and most preferably 50 or more. Further, it is preferably 100 or less, more preferably 80 or less, and most preferably 70 or less.

If b / c is less than 1/5, the thickness of the oil-in-water skin cosmetic when applied may be insufficient. If b / c is 5/1 or more, the freshness of the oil-in-water skin cosmetic may be insufficient.

The random rate x of PO and EO can be obtained from the equation (3).
x = (b + c) / (a + b + c) ... (3)
The random rate x is 0.1 ≦ x ≦ 1. If the random rate x is less than 0.1, the thickness of the oil-in-water skin cosmetic when applied may be insufficient. It is 0.1 or more, more preferably 0.6 or more, further preferably 0.8 or more, and most preferably 0.9 or more. The random rate x is 1 or less, preferably x <1, more preferably 0.99 or less, and most preferably 0.97 or less.

The alkylene oxide derivative of the present invention is defined by the molecular weight obtained by a chromatogram obtained by using a differential refractometer in gel permeation chromatography (GPC). This chromatogram is a graph showing the relationship between the refractive index intensity and the elution time.

In the derivative of the present invention, the ratio Mz / Mw of the weight average molecular weight (Mw) and the z average molecular weight (Mz) obtained from the chromatogram is 5 ≦ Mz / Mw ≦ 60.

Here, Mw and Mz are obtained from GPC by the following equations, respectively.

However, N is the number of polymer molecules, M is the molecular weight, and C is the sample concentration. Mw is a weighted average using the molecular weight as a weight, and Mz is a weighted average using the square of the molecular weight as a weight. Mw is affected by the presence of high molecular weight, and Mz is even greater than Mw and is affected by the presence of high molecular weight. Therefore, the alkylene oxide derivative of the present invention can obtain Mw and Mz as shown in the chromatogram shown in FIG.

When Mz / Mw is smaller than 5, in addition to impairing the thickness at the time of application, the effect of sustaining the moisturizing feeling may be lowered. In order to increase the thickness at the time of application and the effect of sustaining the moisturizing feeling, Mz / Mw is preferably 20 or more, and more preferably 40 or more. When Mz / Mw is larger than 60, the bias on the high molecular weight side in the molecular weight distribution becomes large, and an increase in viscosity is observed, which makes it difficult to disperse and blend in each pharmaceutical product. From this viewpoint, Mz / Mw is preferably 60 or less, and more preferably 50 or less.

In the present invention, gel permeation chromatography (GPC) for determining Mz / Mw is a system dedicated to SHODEX® GPC101GPC, a differential refractometer of SHODEX RI-71s, a guard column of SHODEX KF-G, and a column. As 3 HODEX KF804Ls were continuously mounted, a column temperature of 40 ° C., tetrahydrofuran was flown as a developing solvent at a flow rate of 1 ml / min, 0.1 ml of a 0.1 wt% tetrahydrofuran solution of the obtained reaction product was injected, and BORWIN GPC was injected. A calculation program is used to obtain a chromatogram represented by the refractive index intensity and the elution time.

When the total amount of the oil-in-water emulsified skin cosmetic of the present invention is 100% by weight, the content of the component (A) is 0.1 to 10% by mass. If the content of the component (A) is less than 0.1% by mass, the thickness at the time of coating is impaired and the effect of suppressing whitening is lowered. Therefore, the content is 0.1% by mass or more, but 1% by mass or more. Is preferable. Further, if the content of the component (A) exceeds 10% by mass, the freshness may be lost and stickiness may occur. Therefore, the content is 10% by mass or less, but 8% by mass or less is preferable.

[(B) component]
The component (B) used in the present invention is a monohydric alcohol having 12 to 22 carbon atoms, and examples thereof include lauryl alcohol, myristyl alcohol, cetyl alcohol, stearyl alcohol, behenyl alcohol, and oleyl alcohol. The alkyl group or alkenyl group preferably has 14 to 22 carbon atoms, more preferably 16 to 22 carbon atoms.

When the total amount of the oil-in-water emulsified skin cosmetic of the present invention is 100% by weight, the content of the component (B) is preferably 0.2 to 10% by mass, more preferably 0.2 to 5% by mass. is there. By setting the content in this range, there is an effect that a feeling of use is good and high stability can be obtained. If the content is less than 0.2% by mass, sufficient stability may not be obtained, and if it exceeds 10% by mass, stability such as crystal precipitation may be affected.

[Component (C)]
As the component (C), a solid or paste-like oil having a melting point of 20 to 90 ° C., as long as it can be used in ordinary cosmetics, its properties, composition and the like can be used without particular limitation. Specifically, hydrocarbon oils such as solid paraffin, vaseline, microcrystallin wax, and ceresin, waxes such as beeswax, candelilla wax, lanolin, carnauba wax, jojoba fat, and montan wax, hydrogenated jojoba oil, hardened palm oil, and hydrogenated. Palm oil, palm kernel oil, shea butter, hydrogenated paraffin oil isostearate, phytosteryl hydroxystearate, phytosteryl oleate, polyglyceryl monostearate, polyglyceryl distearate, polyglyceryl monooleate, dipentaerythrityl hexahydroxystearate, tri (capril) Ester oils such as caprin, myristin, and stearic acid) glycerides can be mentioned, but from the viewpoint of usability and the like, wax or hydrocarbon oil is particularly preferable, and specifically, wax and vaseline are preferable.

When the total amount of the oil-in-water emulsified skin cosmetic of the present invention is 100% by weight, the content of the component (C) is 1 to 15% by mass. If the content of the component (C) is less than 1% by mass, the thickness at the time of application is impaired, and the sustainability of the moisturizing feeling is also weakened. Therefore, the content of the component (C) is set to 1.0% by mass or more, preferably 1.5% by mass or more, and more preferably 2% by mass or more. If the content of the component (C) exceeds 15% by mass, it causes sliminess and stickiness. Therefore, the content is 15% by mass or less, preferably 10% by mass or less, and more preferably 8% by mass or less.

(Component (D))
The component (D) is a nonionic surfactant having a hydrocarbon group having HLB 3 to 18 and 12 to 24 carbon atoms or a hydroxyl group-containing hydrocarbon group having HLB 3 to 18 and 12 to 24 carbon atoms.
HLB is an abbreviation for Hirofile-Lipophile Balance, and is a concept that quantifies the balance between hydrophilic groups and lipophilic groups of surfactants. Generally, it is indicated by 0 to 20, and the higher the value, the higher the hydrophilicity.

The HLB is calculated by Griffin's formula.

The component (D) is a nonionic surfactant having a hydrocarbon group having 12 to 24 carbon atoms or a hydroxyl group-containing hydrocarbon group having 12 to 24 carbon atoms from the viewpoint of thermal stability and familiarity with the skin at the time of application. And. This hydrocarbon group is a substituent composed of a carbon atom and a hydrogen atom, and the hydroxyl group-containing hydrocarbon group is a hydrocarbon group having one or more hydroxyl groups.

The number of carbon atoms of the hydrocarbon group or the hydroxyl group-containing hydrocarbon group of the component (D) is more preferably 16 to 24. The hydrocarbon group or the hydroxyl group-containing hydrocarbon group may be linear, branched, or unsaturated. Examples of such a hydrocarbon group or a hydroxyl group-containing hydrocarbon group include a lauryl group, a tridecyl group, a myristyl group, a palmityl group, a cetyl group, an isopalmityl group, a stearyl group, an isostearyl group, an oleyl group, an octyldodecyl group and a behenyl group. Examples thereof include a hydroxystearyl group and a mixed alkyl group thereof.

As the nonionic surfactant satisfying such conditions, one kind or two or more kinds can be used. Among them, one or more polyoxyethylene-added nonionic surfactants having an HLB of 3 or more and less than 10 and one or more polyoxyethylene-added nonionic surfactants having an HLB of 10 or more and 18 or less. It is particularly preferable to combine. The reason is that it has excellent emulsion stability and has the effect of improving the thickness and elongation of the pharmaceutical product.

Nonionic surfactants having an HLB of 3 or more and less than 10 include diglycerin monoisostearate (HLB7), diglycerin diisostearate (HLB4), diglycerin monooleate (HLB7), and diglycerin monostearate (HLB7). ), Sorbitane monolaurate (HLB8), sorbitan monostearate (HLB7), sorbitan monooleate (HLB7), sorbitan sesquioleate (HLB5) and the like.

Examples of nonionic surfactants having an HLB of 10 or more and 18 or less include POE (20 mol) lauryl ether (HLB17), POE (20 mol) cetyl ether (HLB16), POE (20 mol) oleyl ether (HLB15), and the like. POE alkyl ether type nonionic such as POE (12 mol) isostearic acid ester (HLB14), POE (12 mol) oleic acid ester (HLB14), POE (75 mol) stearic acid ester (HLB18) and other POE fatty acid ester type nonionic POEPOP alkyl ether type nonionics such as POE (20 mol) POP (4 mol) cetyl ether (HLB14); POE monoisostearate (60 mol) glyceryl (HLB18), POE triisostearate (30 mol) glyceryl (HLB12), etc. POE glycerin fatty acid ester type nonionic; POE sorbitan fatty acids such as POE monolaurate (20 mol) sorbitan (HLB17), POE monooleate (20 mol) sorbitan (HLB16), POE monostearate (20 mol) sorbitan (HLB16) Ester-type nonionics; POE sorbitol fatty acid ester-type nonions such as POE (60 mol) sorbitol (HLB14), POE tetraisostearate (40 mol) and sorbitol (HLB13); POE (60 mol) hardened castor oil (HLB15), POE (30 mol) Ester oil (HLB12) and the like are exemplified.

The blending ratio of the nonionic surfactant having an HLB of 3 or more and less than 10 and the nonionic surfactant having an HLB of 10 or more and 18 or less is preferably 1:10 to 10: 1 as a weight ratio, and 1: 5 ~ 5: 1 is more preferred.
Is. Emulsification stability is achieved when the amount of nonionic surfactant with an HLB of less than 10 is less than 0.1 times or greater than 10 times the amount of nonionic surfactant with an HLB of 10 or more. Inferior.

When the total amount of the oil-in-water emulsified skin cosmetic of the present invention is 100% by weight, the content of the component (D) is 0.5 to 10% by mass. If the content of the component (D) is less than 0.5% by mass, the thickness and stability at the time of coating are impaired, so the content is 0.5% by mass or more, but 1% by mass or more is preferable. Further, the content of the component (D) is 10% by mass.
If it is more than that, it may cause sliminess, etc., and it may not be familiar to the skin and may feel sticky. Therefore, the content of the component (D) is set to 10% by mass or less, but 8% by mass or less is preferable.

In the present invention, in order to impart the effect of suppressing the thickness at the time of coating and the whitening during coating, the blending ratio (A / C) of the above-mentioned component (A) and component (C) is 1/10 to 5 It is preferably in the range of 1/1, more preferably in the range of 1/3 to 2/1, and most preferably in the range of 1/2 to 1/1.
In order to impart the effect of suppressing freshness and whitening, the blending ratio (A / D) of the above-mentioned component (A) and component (D) is preferably in the range of 1/10 to 5/1. It is more preferably in the range of 1/5 to 3/1, and most preferably in the range of 1/2 to 2/1.

The skin cosmetic of the present invention can be appropriately prepared according to the type of cosmetics or pharmaceuticals to be prepared by using the components (A), (B), (C) and (D). For example, skin cosmetics and pharmaceuticals such as milky lotions, creams, ointments, facial masks, and foundations can be prepared by known methods.

The skin cosmetics of the present invention may contain additives commonly used in cosmetics and pharmaceuticals as long as the performance of the oil-in-water emulsified skin cosmetics of the present invention is not impaired. In addition to the above components (A) to (D), surfactants other than nonionic surfactants such as anionic surfactants, cationic surfactants, and amphoteric surfactants, polyhydric alcohols, and sugars. , Moisturizing agents such as amino acids, thickeners such as water-soluble polymers, physiologically active ingredients such as vitamins, nucleic acids, animal and plant extracts, preservatives, antioxidants, ultraviolet absorbers / scattering agents, pH adjusters, coloring Additives, such as agents and fragrances, which are generally blended in cosmetics, can also be blended as needed. From this viewpoint, the total amount of the additives in the oil-in-water emulsified skin cosmetic of the present invention is preferably 15% by mass or less, more preferably 8% or less.
The balance of the components (A) to (D) and the additive is substantially water.

Hereinafter, the present invention will be described in more detail with reference to Examples and Comparative Examples. The various physical property values were measured by the methods shown below.

[Preparation of (A) component]
(Synthesis Example 1: Synthesis of Example Compound 1)
A 5L autoclave equipped with a thermometer, a pressure gauge, a safety valve, a nitrogen gas blowing pipe, a stirrer, a vacuum exhaust pipe, a cooling coil, and a steam jacket was charged with 100 g of propylene glycol monobutyl ether and 0.03 g of a composite metal cyanide complex catalyst. After nitrogen substitution, the temperature was raised to 110 ° C., 132 g of oxypropylene was added dropwise from a nitrogen gas blowing tube under the condition of 0.3 MPa or less, and the changes over time in the pressure and temperature in the reaction vessel were measured. After some time, the pressure in the reaction vessel dropped sharply. Then, while keeping the inside of the reaction vessel at 90 ° C., a mixture of 1054 g of oxypropylene and 1164 g of oxyethylene was gradually added dropwise from a nitrogen gas blowing tube under the condition of 0.5 MPa or less. After completion of the addition, the reaction was carried out at 90 ° C. for 1 hour, reduced pressure treatment at 75 to 85 ° C. for 1 hour, and then filtration was performed. The obtained compound 1 was measured by gel permeation chromatography.

(Synthesis Example 2-5: Synthesis of Example Compounds 2, 3, 4, and Comparative Example Compound 1)
The compound was synthesized by the same method as in Synthesis Example 1 except for the starting material, the average number of moles of oxypropylene and oxyethylene added, and the random rate. The obtained Example Compounds 2 to 4 and Comparative Example Compound 1 were measured by gel permeation chromatography.

(Synthesis Example 6: Synthesis of Comparative Example Compound 2)
A 5L autoclave equipped with a thermometer, pressure gauge, safety valve, nitrogen gas blowing pipe, stirrer, vacuum exhaust pipe, cooling coil, and steam jacket was charged with 100 g of propylene glycol monobutyl ether and 6.0 g of potassium hydroxide as a catalyst. After nitrogen substitution, the temperature was raised to 110 ° C., and a mixture of 1186 g of oxypropylene and 1164 g of oxyethylene was gradually added dropwise from a nitrogen gas blowing pipe under the condition of 0.5 MPa or less. After completion of the addition, the reaction was carried out at 110 ° C. for 1.5 hours, reduced pressure at 75 to 85 ° C. for 1 hour, then the reaction product was transferred to a 5 L eggplant flask, immediately neutralized with 1N hydrochloric acid, and dehydrated in a nitrogen gas atmosphere. , Filtered.

Table 1 shows the characteristics of Mz / Mw and the compounds obtained from each chromatogram of each Example compound and Comparative Example compound. However, the hydroxyl value is measured in accordance with JIS K-1557-1, and the molecular weight is calculated from the hydroxyl value.

(Examples 1 to 7, Comparative Examples 1 to 3)
An oil-in-water emulsified skin cosmetic was prepared by the following method with the blending ratios shown in Table 3. The common additive components in Table 3 are the 6 components shown in Table 2.

That is, the aqueous phase including the ion-exchanged water and the aqueous component composed of the common additive component and the oily component composed of the component (A), the component (C), the component (D) and the common additive component are mixed, and 75 to 75 to The mixture was heated to 80 ° C., mixed using a homomixer, cooled, and the preservative among the common additive components was added to obtain an oil-in-water emulsified skin cosmetic.

Using the obtained skin cosmetics, four items were evaluated according to the following evaluation criteria. The evaluation results are shown in Table 3.

[Evaluation items and evaluation criteria]
(1) Stickiness With 10 men and women (25 to 48 years old) as panelists, the following scores were given regarding the stickiness when 1.0 g each of the skin cosmetics of the examples and comparative examples was applied to the inside of the right forearm using the middle finger. Evaluated by criteria. The total score of 10 people was calculated and evaluated according to the following evaluation criteria.
(Score criteria)
3 points: I don't feel sticky
2 points: I feel a little sticky
1 point: Feel sticky

(Evaluation criteria)
⊚: 25 points or more ○: 20 points or more, less than 25 △: less than 20 points

(2) Freshness About the freshness when 10 men and women (25 to 48 years old) were used as panelists and 1.0 g of each of the skin cosmetics of Examples and Comparative Examples was applied to the inside of the right forearm using the middle finger. It was evaluated according to the following scoring criteria. The total score of 10 people was calculated and evaluated according to the following evaluation criteria.
(Score criteria)
3 points: Feel the freshness 2 points: I can't say either 1 point: I don't feel the freshness

(Evaluation criteria)
⊚: 25 points or more ○: 20 points or more, less than 25 points △: less than 20 points

(3) Thickness at the time of application About the thickness immediately after applying 1.0 g each of the skin cosmetics of Examples and Comparative Examples to the inside of the right forearm using the middle finger, using 10 men and women (25 to 48 years old) as panelists. , Evaluated according to the following scoring criteria. The total score of 10 people was calculated and evaluated according to the following evaluation criteria.
(Score criteria)
3 points: Feel the thickness enough 2 points: Feel the thickness a little 1 point: Can't feel the thickness

(Evaluation criteria)
⊚: 25 points or more ○: 20 points or more, less than 25 points △: less than 20 points

(4) Add 50 mg each of the skin cosmetics of Examples and Comparative Examples to the white floating artificial leather, apply it to a diameter of 1 cm, set the artificial leather on the friction tester (RUBBING TESTER), and apply the artificial leather with a load of 100 g. The whitening when the leather was rubbed 10 times back and forth was evaluated according to the following evaluation criteria.
(Score criteria)
◎: No white floating ○: Slight white floating △: White floating is seen

注1：「ポリソルベート80」（日油（株）社製）
注2：「モノグリMB」（日油（株）社製）

Note 1: "Polysorbate 80" (manufactured by NOF CORPORATION)
Note 2: "Monoguri MB" (manufactured by NOF CORPORATION)

As is clear from Table 3, in each of Examples 1 to 7, the thickness immediately after application was felt, the skin was well-adapted, there was no stickiness, and the effect of suppressing whitening was excellent.

On the other hand, as is clear from Table 3, none of Comparative Example Compounds 1 and 2, which do not correspond to the alkylene oxide derivative of the present invention, satisfied all of the thickness at the time of application, skin compatibility, and the effect of suppressing whitening. ..

Claims (1)

(A) 0.1 to 10% by mass of the following alkylene oxide derivative,
(B) 0.2 to 10% by mass of monohydric alcohol having 12 to 22 carbon atoms,
(C) 1 to 15% by mass of a solid or paste-like oil having a melting point of 20 to 90 ° C., and (D) a hydrocarbon group having HLB 3 to 18 and 12 to 24 carbon atoms or HLB 3 to 18 and 12 to 12 carbon atoms. 0.5-10% by mass of nonionic surfactant having 24 hydroxyl group-containing hydrocarbon groups
An oil-in-water emulsified skin cosmetic containing.

(A) The ratio Mz / Mw of the weight average molecular weight (Mw) and the z average molecular weight (Mz) represented by the formula (1) and calculated from the chromatogram obtained by gel permeation chromatography measurement is of the formula (2). An alkylene oxide derivative that satisfies the relationship

Z- [O- (PO) _a- (PO) _b / (EO) _c ] -H] _n ... (1)

(In equation (1),
Z represents a residue obtained by removing all hydroxyl groups from a compound having 1 to 24 carbon atoms and 1 to 6 hydroxyl groups.
n represents a number from 1 to 6
PO indicates an oxypropylene group,
EO indicates an oxyethylene group,
a and b indicate the average number of moles of the oxypropylene group PO added, respectively.
c indicates the average number of moles of the oxyethylene group EO added.
a indicates a number from 0 to 100, b indicates a number from 1 to 100, c indicates 1 to 200, a + b + c ≧ 10 and b / c = 1/5 to 5/1.
(PO) _b / (EO) _c indicates that the oxypropylene group PO and the oxyethylene group EO are randomly added, and the random ratio x of the oxypropylene group PO and the oxyethylene group EO is 0.1. ≦ x ≦ 1. )

5 ≤ M _z / M _w ≤ 60 ... (2)

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