JP2021042159A5 - - Google Patents
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- Publication number
- JP2021042159A5 JP2021042159A5 JP2019165017A JP2019165017A JP2021042159A5 JP 2021042159 A5 JP2021042159 A5 JP 2021042159A5 JP 2019165017 A JP2019165017 A JP 2019165017A JP 2019165017 A JP2019165017 A JP 2019165017A JP 2021042159 A5 JP2021042159 A5 JP 2021042159A5
- Authority
- JP
- Japan
- Prior art keywords
- cyclodextrin
- active compound
- pharmaceutically active
- derivative
- mol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229920000858 Cyclodextrin Polymers 0.000 claims 13
- 150000001875 compounds Chemical class 0.000 claims 12
- HFHDHCJBZVLPGP-UHFFFAOYSA-N schardinger α-dextrin Chemical compound O1C(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(O)C2O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC2C(O)C(O)C1OC2CO HFHDHCJBZVLPGP-UHFFFAOYSA-N 0.000 claims 10
- 235000019658 bitter taste Nutrition 0.000 claims 6
- 239000001116 FEMA 4028 Substances 0.000 claims 3
- WHGYBXFWUBPSRW-FOUAGVGXSA-N beta-cyclodextrin Chemical group OC[C@H]([C@H]([C@@H]([C@H]1O)O)O[C@H]2O[C@@H]([C@@H](O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O3)[C@H](O)[C@H]2O)CO)O[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@@H]3O[C@@H]1CO WHGYBXFWUBPSRW-FOUAGVGXSA-N 0.000 claims 3
- 235000011175 beta-cyclodextrine Nutrition 0.000 claims 3
- 229960004853 betadex Drugs 0.000 claims 3
- 229960002496 duloxetine hydrochloride Drugs 0.000 claims 3
- JFTURWWGPMTABQ-UHFFFAOYSA-N n,n-dimethyl-3-naphthalen-1-yloxy-3-thiophen-2-ylpropan-1-amine Chemical compound C=1C=CC2=CC=CC=C2C=1OC(CCN(C)C)C1=CC=CS1 JFTURWWGPMTABQ-UHFFFAOYSA-N 0.000 claims 3
- 238000004519 manufacturing process Methods 0.000 claims 2
- 239000002904 solvent Substances 0.000 claims 2
- 239000004480 active ingredient Substances 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 239000012669 liquid formulation Substances 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
Claims (9)
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2019165017A JP7390830B2 (en) | 2019-09-11 | 2019-09-11 | Bitterness suppressor and method for suppressing bitterness of pharmaceutically active compounds |
JP2023197093A JP2024009146A (en) | 2019-09-11 | 2023-11-21 | Agent and method for inhibiting bitterness of pharmaceutical active compound |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2019165017A JP7390830B2 (en) | 2019-09-11 | 2019-09-11 | Bitterness suppressor and method for suppressing bitterness of pharmaceutically active compounds |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2023197093A Division JP2024009146A (en) | 2019-09-11 | 2023-11-21 | Agent and method for inhibiting bitterness of pharmaceutical active compound |
Publications (3)
Publication Number | Publication Date |
---|---|
JP2021042159A JP2021042159A (en) | 2021-03-18 |
JP2021042159A5 true JP2021042159A5 (en) | 2022-09-15 |
JP7390830B2 JP7390830B2 (en) | 2023-12-04 |
Family
ID=74863742
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2019165017A Active JP7390830B2 (en) | 2019-09-11 | 2019-09-11 | Bitterness suppressor and method for suppressing bitterness of pharmaceutically active compounds |
JP2023197093A Pending JP2024009146A (en) | 2019-09-11 | 2023-11-21 | Agent and method for inhibiting bitterness of pharmaceutical active compound |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2023197093A Pending JP2024009146A (en) | 2019-09-11 | 2023-11-21 | Agent and method for inhibiting bitterness of pharmaceutical active compound |
Country Status (1)
Country | Link |
---|---|
JP (2) | JP7390830B2 (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20230173533A (en) * | 2022-06-17 | 2023-12-27 | 주식회사 코아팜바이오 | New composition of orodispersible powder |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1149991C (en) | 1998-09-15 | 2004-05-19 | 伊莱利利公司 | Treatment of persistent pain |
EP1904039A2 (en) | 2005-06-20 | 2008-04-02 | Cadila Healthcare Ltd. | Controlled release dosage formulation of duloxetine |
US20100215740A1 (en) | 2007-10-10 | 2010-08-26 | Rubicon Research Private Limited | Taste-masked orally disintegrating tablets of memantine hydrochloride |
US8758779B2 (en) | 2009-06-25 | 2014-06-24 | Wockhardt Ltd. | Pharmaceutical composition of duloxetine |
CN102579403B (en) | 2011-12-26 | 2013-08-21 | 天津市嵩锐医药科技有限公司 | Duloxetine hydrochloride drug composition |
US11266658B2 (en) | 2017-03-03 | 2022-03-08 | Ctc Bio, Inc. | Preparation, comprising inclusion complex of varenicline or pharmaceutically acceptable salt thereof, for oral administration |
-
2019
- 2019-09-11 JP JP2019165017A patent/JP7390830B2/en active Active
-
2023
- 2023-11-21 JP JP2023197093A patent/JP2024009146A/en active Pending
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