JP2020527946A5 - - Google Patents
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- JP2020527946A5 JP2020527946A5 JP2020502329A JP2020502329A JP2020527946A5 JP 2020527946 A5 JP2020527946 A5 JP 2020527946A5 JP 2020502329 A JP2020502329 A JP 2020502329A JP 2020502329 A JP2020502329 A JP 2020502329A JP 2020527946 A5 JP2020527946 A5 JP 2020527946A5
- Authority
- JP
- Japan
- Prior art keywords
- different cell
- cell types
- biological sample
- feature
- regression
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201762535645P | 2017-07-21 | 2017-07-21 | |
| US62/535,645 | 2017-07-21 | ||
| PCT/US2018/042949 WO2019018684A1 (en) | 2017-07-21 | 2018-07-19 | SYSTEMS AND METHODS FOR ANALYZING MIXED CELL POPULATIONS |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020527946A JP2020527946A (ja) | 2020-09-17 |
| JP2020527946A5 true JP2020527946A5 (https=) | 2021-08-26 |
| JP7545891B2 JP7545891B2 (ja) | 2024-09-05 |
Family
ID=65015538
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020502329A Active JP7545891B2 (ja) | 2017-07-21 | 2018-07-19 | 混合細胞集団を分析するためのシステムおよび方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US12249401B2 (https=) |
| EP (2) | EP3655955B1 (https=) |
| JP (1) | JP7545891B2 (https=) |
| AU (1) | AU2018304381A1 (https=) |
| WO (1) | WO2019018684A1 (https=) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2971129A1 (en) * | 2015-01-22 | 2016-07-28 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and systems for determining proportions of distinct cell subsets |
| EP3655955B1 (en) * | 2017-07-21 | 2025-04-09 | The Board of Trustees of the Leland Stanford Junior University | Systems and methods for analyzing mixed cell populations |
| US11994512B2 (en) * | 2018-01-04 | 2024-05-28 | Massachusetts Institute Of Technology | Single-cell genomic methods to generate ex vivo cell systems that recapitulate in vivo biology with improved fidelity |
| US11348661B2 (en) | 2018-05-14 | 2022-05-31 | Tempus Labs, Inc. | Predicting total nucleic acid yield and dissection boundaries for histology slides |
| US10957041B2 (en) | 2018-05-14 | 2021-03-23 | Tempus Labs, Inc. | Determining biomarkers from histopathology slide images |
| US20200020419A1 (en) | 2018-07-16 | 2020-01-16 | Flagship Pioneering Innovations Vi, Llc. | Methods of analyzing cells |
| WO2020061123A1 (en) * | 2018-09-18 | 2020-03-26 | California Institute Of Technology | Systems and methods for dissecting heterogeneous cell populations |
| WO2020142563A1 (en) * | 2018-12-31 | 2020-07-09 | Tempus Labs, Inc. | Transcriptome deconvolution of metastatic tissue samples |
| US12205675B2 (en) * | 2019-07-03 | 2025-01-21 | Bostongene Corporation | Techniques for bias correction in sequence data |
| CN114424287A (zh) * | 2019-09-25 | 2022-04-29 | 瑞泽恩制药公司 | 单细胞rna-seq数据处理 |
| CN114746559A (zh) * | 2019-10-18 | 2022-07-12 | 华盛顿大学 | 用于测量细胞状态的方法和系统 |
| US20230027353A1 (en) * | 2019-11-05 | 2023-01-26 | The Board Of Trustees Of The Leland Stanford Junior University | Systems and Methods for Deconvoluting Tumor Ecosystems for Personalized Cancer Therapy |
| CN115136242A (zh) * | 2019-11-08 | 2022-09-30 | 雷杰纳荣制药公司 | 来自大量组织转录组的准确稳健的信息反卷积 |
| US20230049525A1 (en) * | 2019-11-26 | 2023-02-16 | The United states of American, as Representative by the Secretary, Dept.of Health and Human Services | Methods of identifying cell-type-specific gene expression levels by deconvolving bulk gene expression |
| US20230026559A1 (en) * | 2019-12-10 | 2023-01-26 | Novigenix Sa | Analysis of cell signatures for disease detection |
| CN111243677B (zh) * | 2020-01-07 | 2023-04-14 | 北京唐颐惠康生物医学技术有限公司 | 一种基于细胞质量保证的时间控制方法及系统 |
| WO2021148283A1 (en) * | 2020-01-20 | 2021-07-29 | Koninklijke Philips N.V. | Guided analysis of single cell sequencing data using bulk sequencing data |
| EP4101933A4 (en) * | 2020-02-06 | 2024-02-28 | Karydo Therapeutix, Inc. | CORRECTION METHODS FOR SINGLE-CELL RNA-SEQ ANALYSIS DATA SETS, ANALYZING METHODS FOR SINGLE-CELL RNA-SEQ, ANALYZING METHODS FOR CELL TYPE RATIO, AND DEVICES AND COMPUTER PROGRAMS FOR PERFORMING THESE METHODS |
| JP7541585B2 (ja) * | 2020-03-12 | 2024-08-28 | ボストンジーン コーポレイション | 発現データのデコンボリューションのためのシステム及び方法 |
| US20220223227A1 (en) * | 2020-12-16 | 2022-07-14 | Bostongene Corporation | Machine learning techniques for identifying malignant b- and t-cell populations |
| WO2022152672A1 (en) * | 2021-01-12 | 2022-07-21 | Astrazeneca Ab | Graph construction and visualization of multiplex immunofluorescence images |
| EP4278364A1 (en) * | 2021-01-15 | 2023-11-22 | Sanofi | Sensing of biological cells in a sample for cell type identification |
| CN115083617B (zh) * | 2021-03-15 | 2025-02-14 | 复旦大学 | 流行性疾病检测装置及方法 |
| CN113257354B (zh) * | 2021-05-12 | 2022-03-11 | 广州万德基因医学科技有限公司 | 基于高通量实验数据挖掘进行关键rna功能挖掘的方法 |
| CN113593640B (zh) * | 2021-08-03 | 2023-07-28 | 哈尔滨市米杰生物科技有限公司 | 一种鳞癌组织功能状态与细胞组分评估方法及系统 |
| WO2023053702A1 (ja) * | 2021-09-29 | 2023-04-06 | 富士フイルム株式会社 | データ処理方法、データ処理装置、及びデータ処理プログラム |
| WO2023064632A1 (en) * | 2021-10-15 | 2023-04-20 | La Jolla Institute For Immunology | Tissue resident memory cell profiles, and uses thereof in inflammatory and autoimmune diseases |
| CN114038505B (zh) * | 2021-10-19 | 2024-06-14 | 清华大学 | 一种在线整合多来源单细胞数据的方法和系统 |
| WO2023178319A2 (en) * | 2022-03-17 | 2023-09-21 | Washington University | Methods and systems for measuring multiple cell states |
| CN115440303B (zh) * | 2022-11-03 | 2023-02-10 | 杭州联川生物技术股份有限公司 | 一种单细胞转录组低质量细胞过滤方法、介质和设备 |
| US20240177803A1 (en) * | 2022-11-17 | 2024-05-30 | Bostongene Corporation | Comprehensive immunoprofiling of peripheral blood |
| CN120239886A (zh) * | 2022-12-30 | 2025-07-01 | 深圳华大生命科学研究院 | 一种组织切片数据异质性的评估方法以及相关设备 |
| CN116218972A (zh) * | 2023-01-18 | 2023-06-06 | 四川大学华西医院 | 一种肌腱细胞图谱体系及其构建方法与应用 |
| EP4695425A1 (en) | 2023-04-13 | 2026-02-18 | BostonGene Corporation | Pan-cancer tumor microenvironment classification based on immune escape mechanisms and immune infiltration |
| CN116779043A (zh) * | 2023-06-30 | 2023-09-19 | 京东方科技集团股份有限公司 | 细胞比例预测方法、模型生成方法、设备及介质 |
| WO2025064862A1 (en) * | 2023-09-22 | 2025-03-27 | Verily Life Sciences Llc | Modules for single-cell data conversion to transformed bulk-cell data and methods of using the same |
| TW202540631A (zh) * | 2023-12-07 | 2025-10-16 | 美商先勁智醫公司 | 處理來自多個測試之細胞計數資料的方法及系統 |
| CN118675616B (zh) * | 2024-06-11 | 2025-07-15 | 深圳湾实验室 | 一种单细胞测序数据分析方法、设备、介质和程序产品 |
| CN119517178A (zh) * | 2024-11-20 | 2025-02-25 | 泰州赛奥生物有限公司 | 一种在线整合多来源单细胞数据的方法及系统 |
| CN119580839B (zh) * | 2025-02-10 | 2025-07-04 | 深圳大学总医院 | 动脉粥样硬化中内皮细胞异质性智能分析方法及系统 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001063555A2 (en) | 2000-02-24 | 2001-08-30 | Massachusetts Institute Of Technology | Image deconvolution techniques for probe scanning apparatus |
| US7505948B2 (en) | 2003-11-18 | 2009-03-17 | Aureon Laboratories, Inc. | Support vector regression for censored data |
| US20110010099A1 (en) | 2005-09-19 | 2011-01-13 | Aram S Adourian | Correlation Analysis of Biological Systems |
| US20120269418A1 (en) | 2011-04-22 | 2012-10-25 | Ge Global Research | Analyzing the expression of biomarkers in cells with clusters |
| US9020874B2 (en) | 2011-10-31 | 2015-04-28 | Siemens Aktiengesellschaft | Short-term load forecast using support vector regression and feature learning |
| CN103217411B (zh) | 2013-04-15 | 2015-03-25 | 浙江大学 | 基于拉曼光谱的食用植物油中油酸、亚油酸和饱和脂肪酸含量检测方法 |
| US10364469B2 (en) * | 2014-01-16 | 2019-07-30 | Illumina, Inc | Gene expression panel for prognosis of prostate cancer recurrence |
| CA2971129A1 (en) * | 2015-01-22 | 2016-07-28 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and systems for determining proportions of distinct cell subsets |
| US9984199B2 (en) * | 2015-05-21 | 2018-05-29 | Ge Healthcare Bio-Sciences Corp. | Method and system for classification and quantitative analysis of cell types in microscopy images |
| US11225689B2 (en) * | 2016-08-17 | 2022-01-18 | The Broad Institute, Inc. | Method for determination and identification of cell signatures and cell markers |
| US12590288B2 (en) * | 2017-04-12 | 2026-03-31 | The Broad Institute, Inc. | Method of treating an inflammatory disease by administering an agent which binds a surface receptor on a tuft cell that induces an ILC class 2 inflammatory response |
| EP3655955B1 (en) * | 2017-07-21 | 2025-04-09 | The Board of Trustees of the Leland Stanford Junior University | Systems and methods for analyzing mixed cell populations |
| US11756651B2 (en) | 2018-01-04 | 2023-09-12 | Nantomics Llc | Method of treating a tumor in a patient based on an immune gene expression |
| AU2019317440B2 (en) | 2018-08-06 | 2026-01-22 | Tempus Ai, Inc. | A multi-modal approach to predicting immune infiltration based on integrated RNA expression and imaging features |
-
2018
- 2018-07-19 EP EP18835466.6A patent/EP3655955B1/en active Active
- 2018-07-19 WO PCT/US2018/042949 patent/WO2019018684A1/en not_active Ceased
- 2018-07-19 AU AU2018304381A patent/AU2018304381A1/en not_active Abandoned
- 2018-07-19 JP JP2020502329A patent/JP7545891B2/ja active Active
- 2018-07-19 EP EP24223064.7A patent/EP4546353A3/en active Pending
- 2018-07-19 US US16/631,778 patent/US12249401B2/en active Active
-
2025
- 2025-02-19 US US19/057,786 patent/US12562239B2/en active Active
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