JP2020525765A - Il−10、s100bおよびh−fabpマーカー群ならびに該マーカー群の外傷性脳損傷の検出における使用 - Google Patents
Il−10、s100bおよびh−fabpマーカー群ならびに該マーカー群の外傷性脳損傷の検出における使用 Download PDFInfo
- Publication number
- JP2020525765A JP2020525765A JP2019569961A JP2019569961A JP2020525765A JP 2020525765 A JP2020525765 A JP 2020525765A JP 2019569961 A JP2019569961 A JP 2019569961A JP 2019569961 A JP2019569961 A JP 2019569961A JP 2020525765 A JP2020525765 A JP 2020525765A
- Authority
- JP
- Japan
- Prior art keywords
- tbi
- markers
- protein
- fabp
- mtbi
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6872—Intracellular protein regulatory factors and their receptors, e.g. including ion channels
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
- G01N33/6869—Interleukin
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- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Cell Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP17001015 | 2017-06-15 | ||
| EP17001015.1 | 2017-06-15 | ||
| PCT/EP2018/065090 WO2018228927A1 (en) | 2017-06-15 | 2018-06-07 | Il-10, s100b and h-fabp markers and their use in detecting traumatic brain injury |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2020525765A true JP2020525765A (ja) | 2020-08-27 |
| JP2020525765A5 JP2020525765A5 (enExample) | 2021-07-26 |
Family
ID=59091305
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019569961A Pending JP2020525765A (ja) | 2017-06-15 | 2018-06-07 | Il−10、s100bおよびh−fabpマーカー群ならびに該マーカー群の外傷性脳損傷の検出における使用 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20200174015A1 (enExample) |
| EP (1) | EP3639034A1 (enExample) |
| JP (1) | JP2020525765A (enExample) |
| CN (1) | CN110770586A (enExample) |
| AU (1) | AU2018283348A1 (enExample) |
| WO (1) | WO2018228927A1 (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2020157206A1 (en) * | 2019-01-31 | 2020-08-06 | University Of Geneva | Prospective markers in traumatic brain injury (tbi) |
| CN115170540B (zh) * | 2022-07-26 | 2025-07-11 | 浙江工业大学 | 一种基于多模态影像特征融合的轻度创伤性脑损伤分类方法 |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20120322682A1 (en) * | 2011-06-20 | 2012-12-20 | William Marsh Rice University | Brain injury biomarker panel |
| WO2016055148A2 (en) * | 2014-10-06 | 2016-04-14 | Université De Genève | Markers and their use in brain injury |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008008819A2 (en) * | 2006-07-11 | 2008-01-17 | University Of Florida Research Foundation, Inc. | Diagnosis and treatment of neurological inflammation |
| US20170023591A1 (en) * | 2014-04-07 | 2017-01-26 | Iron Horse Diagnostics, Inc. | Traumatic Brain Injury and Neurodegenerative Biomarkers, Methods, and Systems |
-
2018
- 2018-06-07 AU AU2018283348A patent/AU2018283348A1/en not_active Abandoned
- 2018-06-07 JP JP2019569961A patent/JP2020525765A/ja active Pending
- 2018-06-07 US US16/622,287 patent/US20200174015A1/en not_active Abandoned
- 2018-06-07 WO PCT/EP2018/065090 patent/WO2018228927A1/en not_active Ceased
- 2018-06-07 CN CN201880039652.2A patent/CN110770586A/zh active Pending
- 2018-06-07 EP EP18728200.9A patent/EP3639034A1/en not_active Ceased
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20120322682A1 (en) * | 2011-06-20 | 2012-12-20 | William Marsh Rice University | Brain injury biomarker panel |
| WO2016055148A2 (en) * | 2014-10-06 | 2016-04-14 | Université De Genève | Markers and their use in brain injury |
Non-Patent Citations (2)
| Title |
|---|
| DASH, P.K. ET AL.: "Biomarkers for the Diagnosis, Prognosis, and Evaluation of Treatment Efficacy for Traumatic Brain In", NEUROTHERAPEUTICS, vol. 7, JPN6022012426, 2010, pages 100 - 114, XP026824397, ISSN: 0004904286 * |
| SINGH,K. ET AL.: "Longitudinal changes in the DTI measures, anti-GFAP expression and levels of serum inflammatory cyto", EXPERIMENTAL NEUROLOGY, vol. 275, JPN6022012424, 2016, pages 427 - 435, ISSN: 0004904287 * |
Also Published As
| Publication number | Publication date |
|---|---|
| US20200174015A1 (en) | 2020-06-04 |
| AU2018283348A1 (en) | 2020-01-02 |
| EP3639034A1 (en) | 2020-04-22 |
| WO2018228927A1 (en) | 2018-12-20 |
| CN110770586A (zh) | 2020-02-07 |
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