JP2020525765A - Il−10、s100bおよびh−fabpマーカー群ならびに該マーカー群の外傷性脳損傷の検出における使用 - Google Patents

Il−10、s100bおよびh−fabpマーカー群ならびに該マーカー群の外傷性脳損傷の検出における使用 Download PDF

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JP2020525765A
JP2020525765A JP2019569961A JP2019569961A JP2020525765A JP 2020525765 A JP2020525765 A JP 2020525765A JP 2019569961 A JP2019569961 A JP 2019569961A JP 2019569961 A JP2019569961 A JP 2019569961A JP 2020525765 A JP2020525765 A JP 2020525765A
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tbi
markers
protein
fabp
mtbi
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JP2020525765A5 (enExample
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サンシェ ジャン−シャルル
サンシェ ジャン−シャルル
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Geneva, University of
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896Neurological disorders, e.g. Alzheimer's disease
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6872Intracellular protein regulatory factors and their receptors, e.g. including ion channels
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/28Neurological disorders
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6863Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
    • G01N33/6869Interleukin

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2019569961A 2017-06-15 2018-06-07 Il−10、s100bおよびh−fabpマーカー群ならびに該マーカー群の外傷性脳損傷の検出における使用 Pending JP2020525765A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP17001015 2017-06-15
EP17001015.1 2017-06-15
PCT/EP2018/065090 WO2018228927A1 (en) 2017-06-15 2018-06-07 Il-10, s100b and h-fabp markers and their use in detecting traumatic brain injury

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JP2020525765A true JP2020525765A (ja) 2020-08-27
JP2020525765A5 JP2020525765A5 (enExample) 2021-07-26

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JP2019569961A Pending JP2020525765A (ja) 2017-06-15 2018-06-07 Il−10、s100bおよびh−fabpマーカー群ならびに該マーカー群の外傷性脳損傷の検出における使用

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US (1) US20200174015A1 (enExample)
EP (1) EP3639034A1 (enExample)
JP (1) JP2020525765A (enExample)
CN (1) CN110770586A (enExample)
AU (1) AU2018283348A1 (enExample)
WO (1) WO2018228927A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020157206A1 (en) * 2019-01-31 2020-08-06 University Of Geneva Prospective markers in traumatic brain injury (tbi)
CN115170540B (zh) * 2022-07-26 2025-07-11 浙江工业大学 一种基于多模态影像特征融合的轻度创伤性脑损伤分类方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120322682A1 (en) * 2011-06-20 2012-12-20 William Marsh Rice University Brain injury biomarker panel
WO2016055148A2 (en) * 2014-10-06 2016-04-14 Université De Genève Markers and their use in brain injury

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008008819A2 (en) * 2006-07-11 2008-01-17 University Of Florida Research Foundation, Inc. Diagnosis and treatment of neurological inflammation
US20170023591A1 (en) * 2014-04-07 2017-01-26 Iron Horse Diagnostics, Inc. Traumatic Brain Injury and Neurodegenerative Biomarkers, Methods, and Systems

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120322682A1 (en) * 2011-06-20 2012-12-20 William Marsh Rice University Brain injury biomarker panel
WO2016055148A2 (en) * 2014-10-06 2016-04-14 Université De Genève Markers and their use in brain injury

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DASH, P.K. ET AL.: "Biomarkers for the Diagnosis, Prognosis, and Evaluation of Treatment Efficacy for Traumatic Brain In", NEUROTHERAPEUTICS, vol. 7, JPN6022012426, 2010, pages 100 - 114, XP026824397, ISSN: 0004904286 *
SINGH,K. ET AL.: "Longitudinal changes in the DTI measures, anti-GFAP expression and levels of serum inflammatory cyto", EXPERIMENTAL NEUROLOGY, vol. 275, JPN6022012424, 2016, pages 427 - 435, ISSN: 0004904287 *

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US20200174015A1 (en) 2020-06-04
AU2018283348A1 (en) 2020-01-02
EP3639034A1 (en) 2020-04-22
WO2018228927A1 (en) 2018-12-20
CN110770586A (zh) 2020-02-07

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