JP2020513561A - フロー制御装置 - Google Patents
フロー制御装置 Download PDFInfo
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- JP2020513561A JP2020513561A JP2019531148A JP2019531148A JP2020513561A JP 2020513561 A JP2020513561 A JP 2020513561A JP 2019531148 A JP2019531148 A JP 2019531148A JP 2019531148 A JP2019531148 A JP 2019531148A JP 2020513561 A JP2020513561 A JP 2020513561A
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- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502738—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by integrated valves
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- A—HUMAN NECESSITIES
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- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
- A61M5/14276—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body specially adapted for implantation
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
- B01F25/30—Injector mixers
- B01F25/31—Injector mixers in conduits or tubes through which the main component flows
- B01F25/311—Injector mixers in conduits or tubes through which the main component flows for mixing more than two components; Devices specially adapted for generating foam
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
- B01F25/30—Injector mixers
- B01F25/31—Injector mixers in conduits or tubes through which the main component flows
- B01F25/316—Injector mixers in conduits or tubes through which the main component flows with containers for additional components fixed to the conduit
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F33/00—Other mixers; Mixing plants; Combinations of mixers
- B01F33/30—Micromixers
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
- F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
- F04B43/00—Machines, pumps, or pumping installations having flexible working members
- F04B43/02—Machines, pumps, or pumping installations having flexible working members having plate-like flexible members, e.g. diaphragms
- F04B43/04—Pumps having electric drive
- F04B43/043—Micropumps
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
- F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
- F04B53/00—Component parts, details or accessories not provided for in, or of interest apart from, groups F04B1/00 - F04B23/00 or F04B39/00 - F04B47/00
- F04B53/10—Valves; Arrangement of valves
- F04B53/1037—Flap valves
- F04B53/1047—Flap valves the valve being formed by one or more flexible elements
- F04B53/106—Flap valves the valve being formed by one or more flexible elements the valve being a membrane
- F04B53/1067—Flap valves the valve being formed by one or more flexible elements the valve being a membrane fixed at its whole periphery and with an opening at its centre
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
- F16K99/00—Subject matter not provided for in other groups of this subclass
- F16K99/0001—Microvalves
- F16K99/0003—Constructional types of microvalves; Details of the cutting-off member
- F16K99/0015—Diaphragm or membrane valves
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
- F16K99/00—Subject matter not provided for in other groups of this subclass
- F16K99/0001—Microvalves
- F16K99/0003—Constructional types of microvalves; Details of the cutting-off member
- F16K99/0025—Valves using microporous membranes
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
- F16K99/00—Subject matter not provided for in other groups of this subclass
- F16K99/0001—Microvalves
- F16K99/0034—Operating means specially adapted for microvalves
- F16K99/0042—Electric operating means therefor
- F16K99/0049—Electric operating means therefor using an electroactive polymer [EAP]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/0043—Catheters; Hollow probes characterised by structural features
- A61M2025/0058—Catheters; Hollow probes characterised by structural features having an electroactive polymer material, e.g. for steering purposes, for control of flexibility, for locking, for opening or closing
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0809—Geometry, shape and general structure rectangular shaped
- B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
- B01L2300/0867—Multiple inlets and one sample wells, e.g. mixing, dilution
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0887—Laminated structure
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/12—Specific details about materials
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/06—Valves, specific forms thereof
- B01L2400/0633—Valves, specific forms thereof with moving parts
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/08—Regulating or influencing the flow resistance
- B01L2400/082—Active control of flow resistance, e.g. flow controllers
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
- F16K99/00—Subject matter not provided for in other groups of this subclass
- F16K2099/0073—Fabrication methods specifically adapted for microvalves
- F16K2099/0076—Fabrication methods specifically adapted for microvalves using electrical discharge machining [EDM], milling or drilling
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
- F16K99/00—Subject matter not provided for in other groups of this subclass
- F16K2099/0082—Microvalves adapted for a particular use
- F16K2099/0084—Chemistry or biology, e.g. "lab-on-a-chip" technology
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
- F16K99/00—Subject matter not provided for in other groups of this subclass
- F16K2099/0082—Microvalves adapted for a particular use
- F16K2099/0086—Medical applications
- F16K2099/0088—Implanted devices
Abstract
Description
静止状態および作動状態を有する電気活性材料層と、作動不能層(non-actuatable layer)との積層構造であって、電気活性材料層は、作動状態及び静止状態のうちの一方にあるとき、対向する平行表面を有する平面層を有し、作動不能層は、表面のうちの1つに設けられる、積層構造;
電気活性材料層の何れかに形成され、それによって有孔平面電気活性材料層を画定するか、又は、作動不能層に形成されたオリフィスのアレイであって、オリフィスは、静止状態および作動状態の一方で開放され、静止状態および作動状態の他方で閉鎖される、オリフィスのアレイ;
静止状態と作動状態との間で電気活性材料層を駆動するために、平行表面上で電気活性材料層に接触する2つの固体電極を有する電極装置(electrode arrangement);および
電気活性材料層の作動を制御するためのコントローラ。
薬剤のリザーバ;
上記のフロー制御装置;および
薬剤のリザーバとフロー制御装置との間の流体接続部。
異なる流体のリザーバのセット;
各リザーバの流体出力部にあるそれぞれの上述のフロー制御装置;および
フロー制御装置の出力部にある共用混合リザーバ。
検知チャンバ;
チャンバ内に取り付けられた流体センサ;および
検知チャンバ内への流体の流れを制御するための、上記のフロー制御装置。
上記のフロー制御装置;
コントローラは、オリフィスのサイズを制御し、それによって調整可能な粒子フィルタリング機能を提供するように構成される。
− 端部位置が機械的に固定されることができる;
− 双安定EAP設計が使用されることができる;
− 専用のキャパシタまたはひずみゲージが、ひずみを測定するために装置に組み合されることができ、測定および制御ループの一部とすることができる。
ポリフッ化ビニリデン(PVDF)、ポリフッ化ビニリデン‐トリフルオロエチレン(PVDF‐TrFE)、ポリフッ化ビニリデン‐トリフルオロエチレン‐クロロフルオロエチレン(PVDF‐TrFE‐CFE)、ポリフッ化ビニリデン‐トリフルオロエチレン‐クロロトリフルオロエチレン(PVDF‐TrFE‐CTFE)、ポリフッ化ビニリデン‐ヘキサフルオロプロピレン(PVDF‐HFP)、ポリウレタンまたはこれらの混合物。
アクリレート、ポリウレタン、シリコーン。
ポリピロール、ポリ‐3,4‐エチレンジオキシチオフェン、ポリ(p‐フェニレンスルフィド)、ポリアニリン。
Claims (15)
- フロー制御装置であって:
静止状態及び作動状態を有する電気活性材料層と、作動不能層との積層構造であって、前記電気活性材料層は、前記作動状態及び前記静止状態のうちの1つにあるとき、対向する平行表面を有する平面層を有し、前記作動不能層は、前記表面のうちの1つに設けられる、積層構造と;
オリフィスのアレイであって:
前記電気活性材料層に形成され、それによって有孔平面電気活性材料層を画定する;又は、
前記作動不能層に形成され、
前記オリフィスは、前記静止状態および前記作動状態の一方で開放され、前記オリフィスは、前記静止状態および前記作動状態の他方で閉鎖される、オリフィスのアレイと;
前記静止状態と前記作動状態との間で前記電気活性材料層を駆動するために、前記平行表面上で前記電気活性材料層に接触する2つの固体電極を有する電極装置と;
前記電気活性材料層の作動を制御するためのコントローラと;
を有する、
フロー制御装置。 - 前記オリフィスのアレイは前記電気活性材料層に形成され、前記作動不能層は、前記オリフィスの間の位置で前記電気活性材料層の上に設けられた補強要素のアレイを有する、
請求項1に記載のフロー制御装置。 - 前記オリフィスのアレイは、セグメントのグリッドを有する前記作動不能層に形成され、前記オリフィスは、前記グリッドの前記セグメントの間にスペースを有する、
請求項1に記載のフロー制御装置。 - 前記電気活性材料層にチャネルまたは開口部をさらに有する、
請求項3に記載のフロー制御装置。 - 前記オリフィスは、前記静止状態で閉じられる、
請求項1乃至4のいずれか1項に記載のフロー制御装置。 - 前記オリフィスの内部開口部の少なくとも周囲に設けられたシール層を有する、
請求項1乃至5のいずれか1項に記載のフロー制御装置。 - 前記フロー制御装置の最初の作動によって破壊されるように構成された破壊可能な外側保護層を有する、
請求項1乃至6のいずれか1項に記載のフロー制御装置。 - 前記電気活性材料層は、作動されるとき、面内で膨張するかまたは曲がるように構成される、
請求項1乃至7のいずれか1項に記載のフロー制御装置。 - 薬剤のリザーバと;
請求項1乃至8のいずれか1項に記載のフロー制御装置と;
前記薬剤のリザーバと前記フロー制御装置との間の流体接続部と;
を有する、
薬剤送達システム。 - 前記フロー制御装置は、前記フロー制御装置によって形成された第1の面と、ポンピング機能を提供するように第2の電気活性材料アクチュエータによって形成された第2の面とを有するチャンバを有する、
請求項9に記載のシステム。 - 前記フロー制御装置は、前記フロー制御装置によって形成された第1の面を有するチャンバを有し、前記電気活性材料層は、ポンピング機能を提供するように、作動されるとき、曲がるように構成される、
請求項9に記載のシステム。 - 異なる流体のリザーバのセットと;
各前記リザーバの流体出力部にあるそれぞれの請求項1乃至8のいずれか1項に記載のフロー制御装置と;
前記フロー制御装置の出力部にある共用混合リザーバと;
を有する、
流体反応または混合システム。 - 前記共用混合チャンバの入口および出口に設けられたフロー制御バルブをさらに有する、
請求項12に記載のシステム。 - 検知チャンバと;
前記チャンバ内に取り付けられた流体センサと;
前記検知チャンバ内への流体の流れを制御するための、請求項1乃至8のいずれか1項に記載のフロー制御装置と;
を有する、
流体分析システム。 - 請求項1乃至8のいずれか1項に記載のフロー制御装置、を有し、
前記コントローラは、前記オリフィスのサイズを制御し、それによって調整可能な粒子フィルタリング機能を提供するように構成される、
流体フィルタリングシステム。
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EP16203587 | 2016-12-13 | ||
EP16203587.7 | 2016-12-13 | ||
PCT/EP2017/082195 WO2018108799A2 (en) | 2016-12-13 | 2017-12-11 | Flow control device |
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WO2020121608A1 (ja) * | 2018-12-14 | 2020-06-18 | ソニー株式会社 | 音響装置並びに音響システム |
WO2020246962A1 (en) * | 2019-06-04 | 2020-12-10 | Hewlett-Packard Development Company, L.P. | Dilution on microfluidic ejector chips |
CN110677787B (zh) * | 2019-09-23 | 2021-02-19 | 广东小天才科技有限公司 | 振膜、振膜孔径的控制方法及装置、终端设备、存储介质 |
DE102019127262A1 (de) * | 2019-10-10 | 2021-04-15 | Krones Aktiengesellschaft | Transportvorrichtung und Transportverfahren für Behälter |
DE102020207597A1 (de) * | 2020-06-19 | 2021-12-23 | Robert Bosch Gesellschaft mit beschränkter Haftung | Elektroaktive Faser, deren Herstellung und deren Anwendung in Textilien |
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- 2017-12-11 EP EP17832920.7A patent/EP3554703A2/en not_active Withdrawn
- 2017-12-11 US US16/467,077 patent/US11433394B2/en active Active
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US11433394B2 (en) | 2022-09-06 |
EP3554703A2 (en) | 2019-10-23 |
CN110072623A (zh) | 2019-07-30 |
CN110072623B (zh) | 2021-07-30 |
WO2018108799A2 (en) | 2018-06-21 |
WO2018108799A3 (en) | 2018-07-26 |
US20190383281A1 (en) | 2019-12-19 |
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