JP2020509036A - アルツハイマー病を予防的に防止し、その進行を遅らせ、または処置するための方法 - Google Patents

アルツハイマー病を予防的に防止し、その進行を遅らせ、または処置するための方法 Download PDF

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JP2020509036A
JP2020509036A JP2019547373A JP2019547373A JP2020509036A JP 2020509036 A JP2020509036 A JP 2020509036A JP 2019547373 A JP2019547373 A JP 2019547373A JP 2019547373 A JP2019547373 A JP 2019547373A JP 2020509036 A JP2020509036 A JP 2020509036A
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patient
density lipoprotein
high density
blood
lipid
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JP2019547373A
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JP2020509036A5 (enExample
Inventor
ブライアン ジュニア ブルーアー ホリス
ブライアン ジュニア ブルーアー ホリス
エム マタン マイケル
エム マタン マイケル
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HDL Therapeutics Inc
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HDL Therapeutics Inc
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Priority claimed from US15/876,808 external-priority patent/US20190021674A1/en
Application filed by HDL Therapeutics Inc filed Critical HDL Therapeutics Inc
Priority claimed from PCT/US2018/020502 external-priority patent/WO2018160868A1/en
Publication of JP2020509036A publication Critical patent/JP2020509036A/ja
Publication of JP2020509036A5 publication Critical patent/JP2020509036A5/ja
Priority to JP2023007457A priority Critical patent/JP2023071648A/ja
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0033—Features or image-related aspects of imaging apparatus, e.g. for MRI, optical tomography or impedance tomography apparatus; Arrangements of imaging apparatus in a room
    • A61B5/004—Features or image-related aspects of imaging apparatus, e.g. for MRI, optical tomography or impedance tomography apparatus; Arrangements of imaging apparatus in a room adapted for image acquisition of a particular organ or body part
    • A61B5/0042—Features or image-related aspects of imaging apparatus, e.g. for MRI, optical tomography or impedance tomography apparatus; Arrangements of imaging apparatus in a room adapted for image acquisition of a particular organ or body part for the brain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/40—Detecting, measuring or recording for evaluating the nervous system
    • A61B5/4076—Diagnosing or monitoring particular conditions of the nervous system
    • A61B5/4088—Diagnosing of monitoring cognitive diseases, e.g. Alzheimer, prion diseases or dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1275—Lipoproteins or protein-free species thereof, e.g. chylomicrons; Artificial high-density lipoproteins [HDL], low-density lipoproteins [LDL] or very-low-density lipoproteins [VLDL]; Precursors thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4711—Alzheimer's disease; Amyloid plaque core protein

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
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  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Molecular Biology (AREA)
  • Radiology & Medical Imaging (AREA)
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  • Child & Adolescent Psychology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dispersion Chemistry (AREA)
  • Developmental Disabilities (AREA)
  • Psychology (AREA)
  • Physiology (AREA)
JP2019547373A 2017-03-01 2018-03-01 アルツハイマー病を予防的に防止し、その進行を遅らせ、または処置するための方法 Pending JP2020509036A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2023007457A JP2023071648A (ja) 2017-03-01 2023-01-20 アルツハイマー病を予防的に防止し、その進行を遅らせ、または処置するための方法

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US201762465262P 2017-03-01 2017-03-01
US62/465,262 2017-03-01
US201762516100P 2017-06-06 2017-06-06
US62/516,100 2017-06-06
US201762537581P 2017-07-27 2017-07-27
US62/537,581 2017-07-27
US15/876,808 2018-01-22
US15/876,808 US20190021674A1 (en) 2017-01-23 2018-01-22 Methods for Treating Cholesterol-Related Diseases
PCT/US2018/020502 WO2018160868A1 (en) 2017-03-01 2018-03-01 Methods for prophylactically preventing, slowing the progression of, or treating alzheimer's disease

Related Child Applications (1)

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JP2023007457A Division JP2023071648A (ja) 2017-03-01 2023-01-20 アルツハイマー病を予防的に防止し、その進行を遅らせ、または処置するための方法

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JP2020509036A true JP2020509036A (ja) 2020-03-26
JP2020509036A5 JP2020509036A5 (enExample) 2021-03-25

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JP2019547373A Pending JP2020509036A (ja) 2017-03-01 2018-03-01 アルツハイマー病を予防的に防止し、その進行を遅らせ、または処置するための方法
JP2023007457A Pending JP2023071648A (ja) 2017-03-01 2023-01-20 アルツハイマー病を予防的に防止し、その進行を遅らせ、または処置するための方法

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EP (1) EP3589272A4 (enExample)
JP (2) JP2020509036A (enExample)
CN (1) CN110545797A (enExample)
AU (1) AU2018226803A1 (enExample)
CA (1) CA3053491A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023157447A1 (ja) * 2022-02-18 2023-08-24 医療研究開発株式会社 分層方法、および、分層装置

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2019264938A1 (en) * 2018-05-11 2020-12-03 Hdl Therapeutics, Inc. Methods for prophylactically preventing, slowing the progression of, or treating cerebral amyloid angiopathy, alzheimer's disease and/or acute stroke

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005538148A (ja) * 2002-08-26 2005-12-15 リピド サイエンスィズ インコーポレイテッド 脱脂タンパク質粒子を使用したアルツハイマー病治療

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT1641421T (pt) * 2003-07-03 2019-03-27 Hdl Therapeutics Inc Métodos e dispositivos para criar derivados de partículas de hdl com conteúdo de lípidos reduzido
PT2089417E (pt) * 2006-10-12 2015-04-14 Bhi Ltd Partnership Métodos, compostos, composições e veículos para administrar o ácido 3-amino-1-propanossulfónico
US8071100B2 (en) * 2007-02-23 2011-12-06 The Unites States of America as represented by the Secretary of Department of Health and Human Services Monoclonal antibodies that neutralize anthrax toxins
EP2152309B1 (en) * 2007-05-14 2013-07-10 Medtronic, Inc. Methods and device to neutralize soluble toxic agents in the brain

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005538148A (ja) * 2002-08-26 2005-12-15 リピド サイエンスィズ インコーポレイテッド 脱脂タンパク質粒子を使用したアルツハイマー病治療

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023157447A1 (ja) * 2022-02-18 2023-08-24 医療研究開発株式会社 分層方法、および、分層装置
JPWO2023157447A1 (enExample) * 2022-02-18 2023-08-24
JP7496180B2 (ja) 2022-02-18 2024-06-06 医療研究開発株式会社 分層方法、および、分層装置

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Publication number Publication date
CA3053491A1 (en) 2018-09-07
EP3589272A1 (en) 2020-01-08
AU2018226803A1 (en) 2019-08-29
JP2023071648A (ja) 2023-05-23
CN110545797A (zh) 2019-12-06
EP3589272A4 (en) 2020-11-25

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