EP3589272A4 - METHODS FOR PREVENTING PROPHYLAXIS, SLOWING EVOLUTION OR TREATING ALZHEIMER'S DISEASE - Google Patents

METHODS FOR PREVENTING PROPHYLAXIS, SLOWING EVOLUTION OR TREATING ALZHEIMER'S DISEASE Download PDF

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Publication number
EP3589272A4
EP3589272A4 EP18761409.4A EP18761409A EP3589272A4 EP 3589272 A4 EP3589272 A4 EP 3589272A4 EP 18761409 A EP18761409 A EP 18761409A EP 3589272 A4 EP3589272 A4 EP 3589272A4
Authority
EP
European Patent Office
Prior art keywords
slowing
progression
disease
methods
treating alzheimer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
EP18761409.4A
Other languages
German (de)
English (en)
French (fr)
Other versions
EP3589272A1 (en
Inventor
Hollis Bryan BREWER, Jr.
Michael M. MATIN
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
HDL Therapeutics Inc
Original Assignee
HDL Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US15/876,808 external-priority patent/US20190021674A1/en
Application filed by HDL Therapeutics Inc filed Critical HDL Therapeutics Inc
Priority claimed from PCT/US2018/020502 external-priority patent/WO2018160868A1/en
Publication of EP3589272A1 publication Critical patent/EP3589272A1/en
Publication of EP3589272A4 publication Critical patent/EP3589272A4/en
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0033—Features or image-related aspects of imaging apparatus, e.g. for MRI, optical tomography or impedance tomography apparatus; Arrangements of imaging apparatus in a room
    • A61B5/004—Features or image-related aspects of imaging apparatus, e.g. for MRI, optical tomography or impedance tomography apparatus; Arrangements of imaging apparatus in a room adapted for image acquisition of a particular organ or body part
    • A61B5/0042—Features or image-related aspects of imaging apparatus, e.g. for MRI, optical tomography or impedance tomography apparatus; Arrangements of imaging apparatus in a room adapted for image acquisition of a particular organ or body part for the brain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/40—Detecting, measuring or recording for evaluating the nervous system
    • A61B5/4076—Diagnosing or monitoring particular conditions of the nervous system
    • A61B5/4088—Diagnosing of monitoring cognitive diseases, e.g. Alzheimer, prion diseases or dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1275—Lipoproteins or protein-free species thereof, e.g. chylomicrons; Artificial high-density lipoproteins [HDL], low-density lipoproteins [LDL] or very-low-density lipoproteins [VLDL]; Precursors thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4711—Alzheimer's disease; Amyloid plaque core protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Molecular Biology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Medical Informatics (AREA)
  • Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Psychiatry (AREA)
  • Physics & Mathematics (AREA)
  • Hospice & Palliative Care (AREA)
  • Pathology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Toxicology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Dispersion Chemistry (AREA)
  • Developmental Disabilities (AREA)
  • Psychology (AREA)
  • Physiology (AREA)
EP18761409.4A 2017-03-01 2018-03-01 METHODS FOR PREVENTING PROPHYLAXIS, SLOWING EVOLUTION OR TREATING ALZHEIMER'S DISEASE Ceased EP3589272A4 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201762465262P 2017-03-01 2017-03-01
US201762516100P 2017-06-06 2017-06-06
US201762537581P 2017-07-27 2017-07-27
US15/876,808 US20190021674A1 (en) 2017-01-23 2018-01-22 Methods for Treating Cholesterol-Related Diseases
PCT/US2018/020502 WO2018160868A1 (en) 2017-03-01 2018-03-01 Methods for prophylactically preventing, slowing the progression of, or treating alzheimer's disease

Publications (2)

Publication Number Publication Date
EP3589272A1 EP3589272A1 (en) 2020-01-08
EP3589272A4 true EP3589272A4 (en) 2020-11-25

Family

ID=67682480

Family Applications (1)

Application Number Title Priority Date Filing Date
EP18761409.4A Ceased EP3589272A4 (en) 2017-03-01 2018-03-01 METHODS FOR PREVENTING PROPHYLAXIS, SLOWING EVOLUTION OR TREATING ALZHEIMER'S DISEASE

Country Status (5)

Country Link
EP (1) EP3589272A4 (enExample)
JP (2) JP2020509036A (enExample)
CN (1) CN110545797A (enExample)
AU (1) AU2018226803A1 (enExample)
CA (1) CA3053491A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2019264938A1 (en) * 2018-05-11 2020-12-03 Hdl Therapeutics, Inc. Methods for prophylactically preventing, slowing the progression of, or treating cerebral amyloid angiopathy, alzheimer's disease and/or acute stroke
CN116662835A (zh) * 2022-02-18 2023-08-29 医疗研究开发有限公司 分层方法以及分层装置

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040106556A1 (en) * 2002-08-26 2004-06-03 Yanhong Zhu Method of treating and preventing alzheimer disease through administration of delipidated protein and lipoprotein particles
US20050004004A1 (en) * 2003-07-03 2005-01-06 Marc Bellotti Methods and apparatus for creating particle derivatives of HDL with reduced lipid content
US20080146642A1 (en) * 2006-10-12 2008-06-19 Xianqi Kong Methods, compounds, compositions and vehicles for delivering 3-amino-1-propanesulfonic acid
US9580494B2 (en) * 2007-05-14 2017-02-28 Medtronic, Inc. Methods and device to neutralize soluble toxic agents in the brain

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8071100B2 (en) * 2007-02-23 2011-12-06 The Unites States of America as represented by the Secretary of Department of Health and Human Services Monoclonal antibodies that neutralize anthrax toxins

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040106556A1 (en) * 2002-08-26 2004-06-03 Yanhong Zhu Method of treating and preventing alzheimer disease through administration of delipidated protein and lipoprotein particles
US20050004004A1 (en) * 2003-07-03 2005-01-06 Marc Bellotti Methods and apparatus for creating particle derivatives of HDL with reduced lipid content
US20080146642A1 (en) * 2006-10-12 2008-06-19 Xianqi Kong Methods, compounds, compositions and vehicles for delivering 3-amino-1-propanesulfonic acid
US9580494B2 (en) * 2007-05-14 2017-02-28 Medtronic, Inc. Methods and device to neutralize soluble toxic agents in the brain

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
BRUNO P IMBIMBO: "Beta-amyloid immunization approaches for Alzheimer's disease", DRUG DEVELOPMENT RESEARCH, NEW YORK, NY, US, vol. 56, 1 January 2002 (2002-01-01), pages 150 - 162, XP002426086, ISSN: 0272-4391, DOI: 10.1002/DDR.10070 *

Also Published As

Publication number Publication date
CA3053491A1 (en) 2018-09-07
EP3589272A1 (en) 2020-01-08
AU2018226803A1 (en) 2019-08-29
JP2023071648A (ja) 2023-05-23
CN110545797A (zh) 2019-12-06
JP2020509036A (ja) 2020-03-26

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