JP2020505398A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2020505398A5 JP2020505398A5 JP2019540061A JP2019540061A JP2020505398A5 JP 2020505398 A5 JP2020505398 A5 JP 2020505398A5 JP 2019540061 A JP2019540061 A JP 2019540061A JP 2019540061 A JP2019540061 A JP 2019540061A JP 2020505398 A5 JP2020505398 A5 JP 2020505398A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- alkyl
- halo
- independently selected
- pharmaceutically acceptable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNPCT/CN2017/072601 | 2017-01-25 | ||
| CN2017072601 | 2017-01-25 | ||
| PCT/CN2018/073729 WO2018137593A1 (en) | 2017-01-25 | 2018-01-23 | Compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2020505398A JP2020505398A (ja) | 2020-02-20 |
| JP2020505398A5 true JP2020505398A5 (cg-RX-API-DMAC7.html) | 2021-03-11 |
Family
ID=62979030
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019540061A Pending JP2020505398A (ja) | 2017-01-25 | 2018-01-23 | 化合物 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US10858367B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP3573956A4 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2020505398A (cg-RX-API-DMAC7.html) |
| CN (1) | CN110446700A (cg-RX-API-DMAC7.html) |
| BR (1) | BR112019015278A2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA3050156A1 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2018137593A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102558308B1 (ko) * | 2018-09-27 | 2023-07-24 | 주식회사 엘지화학 | 3-아자바이사이클로[3,1,1]헵탄 유도체 및 이를 포함하는 약제학적 조성물 |
| WO2020247298A2 (en) | 2019-06-06 | 2020-12-10 | Merck Sharp & Dohme Corp. | 1-pyrazolyl, 5-, 6- disubstituted indazole derivatives as lrrk2 inhibitors, pharmaceutical compositions, and uses thereof |
| KR20230012464A (ko) * | 2020-02-25 | 2023-01-26 | 브이아이비 브이지더블유 | 류신-풍부 반복 키나제 2 알로스테릭 조절제 |
| WO2022155419A1 (en) * | 2021-01-15 | 2022-07-21 | ESCAPE Bio, Inc. | Indazoles and azaindazoles as lrrk2 inhibitors |
| JP2024541934A (ja) | 2021-10-27 | 2024-11-13 | ハー・ルンドベック・アクチエゼルスカベット | Ｌｒｒｋ２阻害剤 |
| TW202412777A (zh) | 2022-09-15 | 2024-04-01 | 丹麥商Ｈ 朗德貝克公司 | 富白胺酸重複激酶2（lrrk2）抑制劑 |
| WO2025201511A1 (zh) * | 2024-03-29 | 2025-10-02 | 上海京新生物医药有限公司 | 吲唑衍生物及其制备方法与应用 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5752691B2 (ja) * | 2009-09-29 | 2015-07-22 | グラクソ グループ リミテッドＧｌａｘｏ Ｇｒｏｕｐ Ｌｉｍｉｔｅｄ | 新規化合物 |
| EP2489663A1 (en) * | 2011-02-16 | 2012-08-22 | Almirall, S.A. | Compounds as syk kinase inhibitors |
| WO2014134772A1 (en) * | 2013-03-04 | 2014-09-12 | Merck Sharp & Dohme Corp. | Compounds inhibiting leucine-rich repeat kinase enzyme activity |
| MA39219B1 (fr) * | 2014-01-29 | 2018-11-30 | Glaxosmithkline Ip Dev Ltd | Nouveaux composés inhibiteurs de la kinase lrrk2 utilisés pour le traitement du parkinson, de l’alzheimer et de la sclérose latérale amyotrophique |
| EP3190889B1 (en) | 2014-09-03 | 2021-11-17 | Merck Sharp & Dohme Corp. | Compounds inhibiting leucine-rich repeat kinase enzyme activity |
| KR20180030201A (ko) * | 2015-07-23 | 2018-03-21 | 글락소스미스클라인 인털렉츄얼 프로퍼티 디벨로프먼트 리미티드 | 화합물 |
| CN110225910A (zh) * | 2017-01-25 | 2019-09-10 | 葛兰素史密斯克莱知识产权发展有限公司 | 化合物 |
-
2018
- 2018-01-23 JP JP2019540061A patent/JP2020505398A/ja active Pending
- 2018-01-23 EP EP18745270.1A patent/EP3573956A4/en not_active Withdrawn
- 2018-01-23 BR BR112019015278A patent/BR112019015278A2/pt not_active Application Discontinuation
- 2018-01-23 CN CN201880019059.1A patent/CN110446700A/zh active Pending
- 2018-01-23 WO PCT/CN2018/073729 patent/WO2018137593A1/en not_active Ceased
- 2018-01-23 US US16/480,797 patent/US10858367B2/en not_active Expired - Fee Related
- 2018-01-23 CA CA3050156A patent/CA3050156A1/en not_active Abandoned