JP2020500519A5 - - Google Patents
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- Publication number
- JP2020500519A5 JP2020500519A5 JP2019528500A JP2019528500A JP2020500519A5 JP 2020500519 A5 JP2020500519 A5 JP 2020500519A5 JP 2019528500 A JP2019528500 A JP 2019528500A JP 2019528500 A JP2019528500 A JP 2019528500A JP 2020500519 A5 JP2020500519 A5 JP 2020500519A5
- Authority
- JP
- Japan
- Prior art keywords
- nucleic acid
- reactant
- amino
- modified
- water
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16201391 | 2016-11-30 | ||
| EP16201391.6 | 2016-11-30 | ||
| PCT/EP2017/001399 WO2018099600A1 (en) | 2016-11-30 | 2017-11-30 | A method for polyalkoxylation of nucleic acids that enables recovery and reuse of excess polyalkoxylation reagent |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2020500519A JP2020500519A (ja) | 2020-01-16 |
| JP2020500519A5 true JP2020500519A5 (https=) | 2021-01-14 |
| JP7113825B2 JP7113825B2 (ja) | 2022-08-05 |
Family
ID=57544196
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019528500A Active JP7113825B2 (ja) | 2016-11-30 | 2017-11-30 | 過剰のポリアルコキシル化試薬の回収及び再使用を可能にする核酸のポリアルコキシル化法 |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US11459352B2 (https=) |
| EP (1) | EP3548089B1 (https=) |
| JP (1) | JP7113825B2 (https=) |
| KR (1) | KR102611562B1 (https=) |
| CN (1) | CN110121363B (https=) |
| AU (1) | AU2017369207C1 (https=) |
| BR (1) | BR112019009373A8 (https=) |
| CA (1) | CA3043478C (https=) |
| DE (1) | DE17829597T1 (https=) |
| ES (1) | ES2975373T3 (https=) |
| MX (1) | MX2019006363A (https=) |
| RU (1) | RU2765027C2 (https=) |
| SG (1) | SG10202105648XA (https=) |
| WO (1) | WO2018099600A1 (https=) |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004016767A2 (en) * | 2002-08-19 | 2004-02-26 | The President And Fellows Of Harvard College | Evolving new molecular function |
| PL1620118T3 (pl) * | 2003-04-08 | 2014-11-28 | Yeda Res & Dev | Leki odwracalnie pegylowane |
| WO2005042563A2 (en) * | 2003-10-22 | 2005-05-12 | Akzo Nobel N.V. | Process for incrasing protein pegylation reaction yields by diafiltration ultrafiltration |
| KR101418369B1 (ko) * | 2005-05-04 | 2014-07-24 | 녹손 파르마 아게 | 스피에겔머들의 신규 용도 |
| US9388457B2 (en) * | 2007-09-14 | 2016-07-12 | Affymetrix, Inc. | Locus specific amplification using array probes |
| DE102007058713A1 (de) * | 2007-12-06 | 2009-06-10 | Evonik Goldschmidt Gmbh | Silicon(meth-)acrylat-Partikel, Verfahren zu deren Herstellung sowie deren Verwendung |
| US8207298B2 (en) | 2008-05-01 | 2012-06-26 | Archemix Corp. | Methods of separating biopolymer conjugated molecules from unconjugated molecules |
| TWI578992B (zh) | 2009-04-30 | 2017-04-21 | 諾克森製藥股份有限公司 | 與鐵調節激素（ｈｅｐｃｉｄｉｎ）結合之核酸類 |
| EA201390172A1 (ru) | 2011-04-26 | 2013-09-30 | ОБЩЕСТВО С ОГРАНИЧЕННОЙ ОТВЕТСТВЕННОСТЬЮ "НоваМедика" | Способ получения пэгилированных олигонуклеотидов |
| JP2014533098A (ja) | 2011-10-21 | 2014-12-11 | ノクソン・ファルマ・アクチエンゲゼルシャフト | グルカゴン結合核酸 |
| AU2013231638B2 (en) * | 2012-03-16 | 2017-10-12 | Merck Patent Gmbh | Targeting aminoacid lipids |
| WO2015113776A1 (en) * | 2014-02-03 | 2015-08-06 | Noxxon Pharma Ag | Methods for the preparation of a polyalkoxylated nucleic acid molecule |
-
0
- DE DE17829597.8T patent/DE17829597T1/de active Pending
-
2017
- 2017-11-30 CN CN201780073303.8A patent/CN110121363B/zh active Active
- 2017-11-30 KR KR1020197018821A patent/KR102611562B1/ko active Active
- 2017-11-30 AU AU2017369207A patent/AU2017369207C1/en active Active
- 2017-11-30 EP EP17829597.8A patent/EP3548089B1/en active Active
- 2017-11-30 RU RU2019120021A patent/RU2765027C2/ru active
- 2017-11-30 JP JP2019528500A patent/JP7113825B2/ja active Active
- 2017-11-30 CA CA3043478A patent/CA3043478C/en active Active
- 2017-11-30 MX MX2019006363A patent/MX2019006363A/es unknown
- 2017-11-30 WO PCT/EP2017/001399 patent/WO2018099600A1/en not_active Ceased
- 2017-11-30 BR BR112019009373A patent/BR112019009373A8/pt not_active Application Discontinuation
- 2017-11-30 ES ES17829597T patent/ES2975373T3/es active Active
- 2017-11-30 SG SG10202105648XA patent/SG10202105648XA/en unknown
- 2017-11-30 US US16/464,291 patent/US11459352B2/en active Active
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