JP2020073611A - Insect pest-controlling agent - Google Patents

Abstract

To provide an insect pest-controlling agent capable of sufficiently obtaining an action inhibitory effect on an insect pest in a short period of time while having a composition substantially free from adverse effects on the human body.SOLUTION: An insect pest-controlling agent which is allowed to adhere to an insect pest, includes cis-1,1,1,4,4,4-hexafluoro-2-butene and an alternative fluorocarbon for cooling.SELECTED DRAWING: Figure 1

Description

  The present invention relates to a pest control agent for controlling various pests.

  BACKGROUND ART Conventionally, pest control aerosols, which are obtained by filling a pest control agent in an aerosol container, have been used for controlling pests such as cockroaches. A chemical containing an insecticidal component is generally mixed with this type of pest control agent. Since insecticidal components do not have a good effect on the human body, use pest control aerosols from the user's side, for example, in places where food and tableware are placed or where infants are present. There were actual situations such as refraining from using it or not using it at all.

  Therefore, in recent years, without using a chemical containing an insecticidal component, an insect pest control aerosol containing an alternative chlorofluorocarbon having a cooling action that has almost no adverse effect on the human body has come to be used (for example, Patent Document 1). 1 and 2). The pest control aerosols of Patent Documents 1 and 2 are obtained by filling the aerosol container with alternative CFCs. When the user pushes the head cap to attach the alternative CFCs ejected from the nozzles to the pests, the heat of vaporization of the alternative CFCs instantly cools the pests and hinders the behavior of the pests.

JP, 2009-227662, A JP, 2014-79255, A

  By the way, as described above, there is an advantage that a pest control agent having almost no adverse effects on the human body can be obtained by using, as an active ingredient for controlling pests, a CFC substitute instead of a conventional chemical containing an insecticidal component.

  However, assuming the actual use situation of the pest control agent, the pest often appears suddenly and moves, and there is also a psychological function and impatience to keep away from the pest. It is difficult to accurately attach the pesticide to the pests. Furthermore, when the pest control agent adheres to the pests, the pests may reflexively escape. Since conventional insecticidal components act directly on the nervous system of pests, even if they are a little off-target, they quickly show their effects if they adhere to pests. In terms of this, it is extremely low, and it is not enough to attach the insects to the pests, and the effect only appears after cooling the insects. Therefore, unless the insects are attached to the insects as intended, there is a possibility that the action inhibiting effect cannot be sufficiently obtained.

  Further, since the pest itself has a certain amount of heat, even if the pest control agent as disclosed in Patent Documents 1 and 2 adheres to the pest, if the adhered amount is small, the action inhibiting effect may not be obtained. Therefore, the user has the impression that the pest control agent by the cooling action does not work, which leads to the spread of safe pest control agents.

  The present invention has been made in view of the above points, and its purpose is to provide a pest control which can sufficiently obtain a behavior inhibitory effect against pests in a short time while having a composition with almost no adverse effect on the human body. To provide the agent.

  In order to achieve the above-mentioned object, the present invention provides a pest control agent containing cis-1,1,1,4,4,4-hexafluoro-2-butene which has almost no adverse effect on the human body.

  A first invention relates to a pest control agent to be attached to a pest, which comprises cis-1,1,1,4,4,4-hexafluoro-2-butene and hydrofluorocarbon and / or hydrofluoro as a CFC alternative for cooling. It is characterized by containing an olefin.

  According to this configuration, when cis-1,1,1,4,4,4-hexafluoro-2-butene attaches to the pest, cis-1,1,1,4,4,4-hexafluoro-2 -The effect of inhibiting the behavior of pests by butene is obtained. The action-inhibitory effect of cis-1,1,1,4,4,4-hexafluoro-2-butene on pest behavior was not due to cooling, but cis-1,1,1,4,4,4-hexa This is due to the unique motor function-lowering effect of fluoro-2-butene, and its effect appears quickly.

  Since cis-1,1,1,4,4,4-hexafluoro-2-butene has almost no adverse effects on the human body as well as CFC alternatives, it can be used as a pest control agent that is safe for the human body. become.

  Further, it is characterized in that it further includes a CFC substitute for cooling the pests by heat of vaporization.

  That is, the action of pests is inhibited by cis-1,1,1,4,4,4-hexafluoro-2-butene before the cooling effect of the CFC substitute for cooling appears. Then, the harmful insects are cooled and controlled by the heat of vaporization of the CFC substitute for cooling. In addition, cis-1,1,1,4,4,4-hexafluoro-2-butene can quickly obtain the action-inhibiting effect of insect pests, which makes it easier to further attach insecticides to insect pests. , The certainty of pest control is increased.

  Further, since the CFC substitute for cooling also functions as a propellant, it is not necessary to blend a propellant such as dimethyl ether.

  According to the first aspect of the present invention, since it contains cis-1,1,1,4,4,4-hexafluoro-2-butene, the composition has almost no adverse effects on the human body, while it has a behavioral inhibitory effect against pests. Can be obtained in a short time.

  In addition, since it contains an alternative CFC for cooling, the insect pests can be protected by the cooling effect of an alternative CFC for cooling while the behavior of the insect is inhibited by cis-1,1,1,4,4,4-hexafluoro-2-butene. Can be effectively controlled.

It is a schematic diagram explaining a use state of a pest control agent concerning an embodiment, and shows Test example 1. It is a figure corresponding to Drawing 1 concerning example 2 of an examination.

  Hereinafter, embodiments of the present invention will be described in detail with reference to the drawings. The following description of the preferred embodiments is merely an example in essence, and is not intended to limit the present invention, its application, or its application.

  FIG. 1 is a diagram illustrating a usage state of a pest control agent according to an embodiment of the present invention. The pest control agent according to the embodiment is filled in the aerosol container 1 and ejected from the aerosol container 1 to be attached to the pest 2. As the aerosol container 1, a general one can be used, and it has a container body 1a made of a pressure resistant container and a head cap 1b provided on the upper portion of the container body 1a. Although not shown, a valve having a vertically moving stem is provided on the top of the container body 1a. The valve is opened by pushing the stem downward, and the inside of the stem communicates with the inside of the container body 1a in the opened state. Further, a passage (not shown) communicating with the inside of the stem is formed inside the head cap 1b. A nozzle 1c provided on the head cap 1b is connected to the downstream end of this passage. The structure of the aerosol container 1 is not limited to the above-mentioned structure, and various aerosol containers can be used.

  The pest control agents are cis-1,1,1,4,4,4-hexafluoro-2-butene, a cooling alternative CFC for cooling the insects by heat of vaporization, and a cooling alternative CFC and cis-1. And 1,1,1,4,4,4-hexafluoro-2-butene from the aerosol container 1. cis-1,1,1,4,4,4-hexafluoro-2-butene is a kind of fluorine compound, and has the characteristics of a boiling point of 33 ° C. and low flammability. Since cis-1,1,1,4,4,4-hexafluoro-2-butene has almost no adverse effect on the human body as does the alternative CFC, it can be used as a pest control agent that is safe for the human body. ..

The alternative CFCs for cooling include hydrofluorocarbons and hydrofluoroolefins that, when attached to the pests 2, cool the pests 2 by the heat of vaporization and inhibit the behavior of the pests 2. These alternative CFCs for cooling have a chemical property of extremely low flammability. In this embodiment, HFC-152a (1,1-difluoroethane) (chemical formula: CHF ₂ CH ₃ , CAS No. 75-37-6), HFC-134a (1 , 1,1,2-Tetrafluoroethane) (chemical formula: CH ₂ FCF ₃ , CAS No. 811-97-2), HFO-1234yf (2,3,3,3-tetrafluoropropene) (chemical formula: CF ₃ CF = CH ₂ , CAS No. 754-12-1), HFO-1234ze (1,3,3,3-tetrafluoropropene) (chemical formula: CF ₃ CH = CFH, CAS No. 1645-83-6) and the like. Can be mentioned. The HFO-1234yf and HFO-1234ze have chemical properties such as a global warming potential (GWP) lower than that of HFC-152a and a flammability lower than that of HFC-152a. Furthermore, HFO-1234ze is Not flammable, ie non-flammable. From these things, it is also preferable to use HFO-1234yf or HFO-1234ze as the alternative CFC for cooling, and in particular, HFO-1234ze is more preferable in view of chemical properties.

  The propellant is, for example, dimethyl ether, normal butane, isobutane, propane, or liquefied petroleum gas (LPG) which is a mixed gas thereof. However, since these are flammable, if they are mixed in a large amount, the flammability will be increased. Therefore, when these are mixed, it is necessary that the blending amount of the CFC substitute for cooling does not fall below 75% by volume. When the blending amount of the CFC substitute for cooling is less than 75% by volume, there is a risk of causing a flashback phenomenon when directly injected into a fire source or the like. Further, hydrocarbons having a high boiling point and having 5 to 6 carbon atoms, such as normal pentane, isopentane, and normal hexane, may be mixed, but since their combustibility is high, it is necessary to set their mixing ratio low. Besides, it is also possible to mix a compressed gas such as nitrogen gas, compressed air or carbon dioxide gas. Since the alternative CFC for cooling also functions as a propellant, the propellant may or may not be blended. That is, it can be used as an aerosol without blending a propellant.

  In addition, regarding the blending of the pest behavior inhibitor A for cases other than HFC-152a, for example, in the case of HFO-1234ze, considering the problem of increased flammability, that is, the problem of flashback phenomenon, etc., HFC-152a Although the amount can be reduced as compared with the above, if the amount is less than 50% by volume, the above problems may occur, and it is preferable to add 50% by volume or more. In short, the compounding amount of HFO-1234ze is 50 to 100% by volume.

  The pest control agent of the present embodiment is suitable for indoor use because it has the characteristics that the pest control agent does not remain at the sprayed portion and that it does not contain an insecticidal component. The pests to be controlled by this pest control agent include cockroaches, black cockroaches, American cockroaches, black-tailed cockroaches, cockroaches such as Yamato cockroaches, spiders such as Red-backed Spiders, Nephila spiders, ants such as centipedes, Aphididae, stink bugs and bed bugs. Lice, etc. In addition, flying insects such as flies such as house flies, Hime flies, Sentinic flies, Drosophila melanogaster, Drosophila melanogaster, Drosophila melanogaster and fleas, mosquitoes such as Culex pipiens and Aedes albopictus, moths such as bees and Aedes aegypti are also control target pests. Furthermore, the pest control agent and the pyrethroid-resistant pest according to the present embodiment can also exert a control effect. This is because the prescription does not contain insecticidal components.

  In addition, the pest control agent can be used in various places such as a kitchen near food and tableware, a general household including a room for infants, a restaurant, a hospital and the like.

  Further, pest control agents include, for example, natural essential oils such as citronella oil, thyme oil, peppermint oil, lavender oil, coriander oil, cedarwood oil, funnel oil, chamomile oil, cinnamon oil, pimento oil, geranium oil, cumin oil, mint. Oil, clove oil, hiba oil, lemongrass oil, etc. may be added. These components may be used alone or in admixture of two or more, depending on the application.

  The pest control agent is 1,1,1,2,2,3,4,5,5,5-decafluoropentane (Mitsui DuPont Fluorochemical Co., Ltd., trade name: Bertrel XF) which is a nonflammable solvent. ), 3M Japan Novec 7100, Novec 7200, etc. can also be added. Novec 7100 includes methyl nonafluorobutyl ether (chemical formula: CF3 (CF2) 3OCH3, CAS No. 163702-07-6) and methyl nonafluoroisobutyl ether (chemical formula: CF2HOCH2CF (CF3) 2, CAS No. 163702-08-7). ) Is a mixture of. In addition, Novec 7200 includes ethyl nonafluorobutyl ether (chemical formula: (CF2) 3CF3OCH2CH3, CAS No. 163702-05-4) and ethyl nonafluoroisobutyl ether (chemical formula: CF2CF (CF3) 2OCH2CH3, CAS No. 163702-06-. It is a mixture of 5). These can also be mixed and used in an arbitrary ratio.

  By using a non-flammable solvent in this way, ignition is less likely to occur. Furthermore, since these solvents have a low boiling point and evaporate at room temperature, they are unlikely to remain after adhering to floor materials and the like, and do not leave an injection trace when used indoors. In addition, since it has high adhesion and penetration to pests, and 1,1,1,2,2,3,4,5,5,5,5-decafluoropentane itself has a cooling action, The cooling effect can be further enhanced.

  Further, the pests can be controlled even more effectively by using a drug having a high permeability to adhere to the pests and a high choking effect. Examples of the agent include hydrocarbons such as aliphatic hydrocarbons, aromatic hydrocarbons and alicyclic hydrocarbons, alcohols such as ethanol, isopropyl alcohol and methanol, esters, vegetable oils, animal oils, water and the like. Can be mentioned.

  In addition, other drugs and the like can be added within a range that does not impair the action inhibition effect against pests and does not impair the safety to the human body.

  Examples of the present invention will be described below, but the present invention is not construed as being limited to the examples.

(Test Example 1)
As shown in Table 1, Test Example 1 is a test for obtaining a difference in efficacy between Comparative Example 1 and Examples 1 to 7.

  The test method is as shown in FIG. First, an aerosol container 1 filled with the pest control agents of Comparative Example 1 and Examples 1 to 7 is prepared. Then, the pest 2 which is a test insect is placed on the flooring 3. Pest 2 was one adult female of the Black Cockroach. The pest 2 is released so that it can move freely inside the square area (the dimension A on one side) on the upper surface of the flooring 3. The dimension A was 30 cm. The aerosol container 1 is arranged diagonally above the pest 2 and is set so that the distance L between the tip opening of the nozzle 1c and the pest 2 is 60 cm. The state of the pest 2 was observed immediately after injection and after 10 seconds from the injection. The injection time is all 4 seconds, and the injection amount is 16 ml. The room temperature of the test room was 23 ° C.

  The pest control agent of Comparative Example 1 contains HFO-1234ze and dimethyl ether (DME), and does not contain cis-1,1,1,4,4,4-hexafluoro-2-butene. The content of HFO-1234ze is 180 ml (70 w / v%), the content of DME is 120 ml (27 w / v%), and the total is 300 ml. In addition, "w / v%" is a weight volume percentage.

  The pest control agent of Example 1 contains HFO-1234ze, DME, and cis-1,1,1,4,4,4-hexafluoro-2-butene, and HFO-1234ze is 125.91 ml, DME was 103.02 ml, and cis-1,1,1,4,4,4-hexafluoro-2-butene was 1.07 ml (0.65 w / v%), and the total was 230 ml.

  The pest control agent of Example 2 contains HFO-1234ze, DME, and cis-1,1,1,4,4,4-hexafluoro-2-butene, and HFO-1234ze is 125.83 ml, DME was 102.95 ml, and cis-1,1,1,4,4,4-hexafluoro-2-butene was 1.21 ml (0.74 w / v%), and the total was 230 ml.

  The pest control agent of Example 3 contains HFO-1234ze, DME, and cis-1,1,1,4,4,4-hexafluoro-2-butene, and HFO-1234ze is 125.75 ml, DME was 102.89 ml, cis-1,1,1,4,4,4-hexafluoro-2-butene was 1.36 ml (0.83 w / v%), and the total was 230 ml.

  The pest control agent of Example 4 contains HFO-1234ze, DME, and cis-1,1,1,4,4,4-hexafluoro-2-butene, and HFO-1234ze is 125.68 ml, DME was 102.83 ml, and cis-1,1,1,4,4,4-hexafluoro-2-butene was 1.50 ml (0.91 w / v%), and the total was 230 ml.

  The pest control agent of Example 5 contains HFO-1234ze, DME, and cis-1,1,1,4,4,4-hexafluoro-2-butene, and HFO-1234ze is 125.60 ml, DME was 102.76 ml, and cis-1,1,1,4,4,4-hexafluoro-2-butene was 1.64 ml (1.00 w / v%), and the total was 230 ml.

  The pest control agent of Example 6 contains HFO-1234ze, DME, and cis-1,1,1,4,4,4-hexafluoro-2-butene, and HFO-1234ze is 121.98 ml, DME was 99.80 ml, cis-1,1,1,4,4,4-hexafluoro-2-butene was 8.21 ml (5.00 w / v%), and the total was 230 ml.

  The pest control agent of Example 7 contains HFO-1234ze, DME, and cis-1,1,1,4,4,4-hexafluoro-2-butene, and HFO-1234ze has 117.46 ml, DME was 96.11 ml, cis-1,1,1,4,4,4-hexafluoro-2-butene was 16.43 ml (10.00 w / v%), and the total was 230 ml.

  Further, “△” shown in Table 1 indicates that the speed of loitering does not change much compared to that before injection, but abnormal movement is observed, and “◯” clearly indicates that compared to before injection. This is a case where the speed of loitering is slowed down, and "◎" is a case where the person does not move or cannot wander. The test is performed 5 times in each of Comparative Example 1 and Examples 1 to 7.

  As can be seen from Table 1, in Comparative Example 1, there were pests 2 that became “Δ” immediately after injection, and in these pests 2, the speed of loitering did not change much, whereas in Example, In 1 to 7, none of the pests 2 became “Δ” immediately after injection. In other words, when cis-1,1,1,4,4,4-hexafluoro-2-butene attaches to the pest, the pest caused by cis-1,1,1,4,4,4-hexafluoro-2-butene The action inhibition effect of is obtained. The action-inhibitory effect of cis-1,1,1,4,4,4-hexafluoro-2-butene on pest behavior was not due to cooling, but cis-1,1,1,4,4,4-hexa It can be seen that this is due to the specific motor function-lowering effect of fluoro-2-butene, and its effect appears quickly.

  In addition, in Example 2, there was no pest 2 that had a “Δ” immediately after the injection and 10 seconds after the injection. Therefore, by setting the content of cis-1,1,1,4,4,4-hexafluoro-2-butene to 0.74 w / v% or more, when the pest control agent is attached to the pest 2, In particular, it can be seen that the action-inhibiting effect within 10 seconds after attachment is significantly increased. A particularly preferable range of the content of cis-1,1,1,4,4,4-hexafluoro-2-butene is 0.83 w / v% or more. By setting this range, the body moves immediately after injection. There were 3 pests that did not. A more preferable lower limit of the content of cis-1,1,1,4,4,4-hexafluoro-2-butene is 0.91 w / v% or more.

  Also, it can be seen that as the content of cis-1,1,1,4,4,4-hexafluoro-2-butene is increased, the action inhibiting effect of pest 2 is enhanced, but cis-1,1,1,4 Increasing the content of 4,4,4-hexafluoro-2-butene increases the amount of chemicals remaining on the flooring 3 after spraying and deteriorates cleanliness. Therefore, the upper limit is preferably 10 w / v% or less, more preferably Is 5 w / v% or less. Further, the cost of the pest control agent can be reduced by setting the upper limit of cis-1,1,1,4,4,4-hexafluoro-2-butene to 10 w / v% or less.

(Test Example 2)
Test Example 2 is a test for obtaining a difference in efficacy between Comparative Example 1 and Example 2 against various pests, as shown in Table 2.

  The test method is as shown in FIG. First, an aerosol container 1 filled with each pest control agent of Comparative Example 1 and Example 2 is prepared. Then, the insect pest 2 as the test insect is placed on the inclined plane, and the cylindrical member 4 having open ends is placed so as to surround the insect pest 2. One pest 2 was put into the cylindrical member 4. The pest 2 is released inside the cylindrical member 4 so that it can move freely. The inner diameter B of the cylindrical member 4 was 20 cm, and the height was 20 cm. The aerosol container 1 is arranged diagonally above the pest 2 and is set so that the distance L between the tip end of the nozzle 1c and the pest 2 is 60 cm. The state of Pest 2 immediately after injection was observed. The injection time is as shown in Table 2 and is changed depending on the pest 2. The room temperature of the test room was 23 ° C.

  In Table 1, "x" means that there was no effect, "△" means that there was not much effect, "○" means that there was an effect, and "◎". Is very effective. The test is performed three times in each of Comparative Example 1 and Example 2.

  As can be seen from Table 2, Example 2 was effective against all the pests 2, and most of them were extremely effective. On the other hand, Comparative Example 1 had little or no effect on Aphid anteri and centipede.

  Since the composition of Example 2 was effective against various pests, it is presumed that the compositions of other Examples 1, 3 to 7 are also effective. From this, the pest control agent according to the embodiment of the present invention, not only cockroaches, but also moths, stink bugs, lice, ants, spiders, centipedes high behavior inhibitory effect can be obtained. I understand. Particularly for moths, a very high effect was obtained even with an extremely short injection time of 2 seconds.

(Test Example 3)
Test Example 3 is a test for confirming the efficacy of Example 8 in which the propellant is LPG and the alternative CFC for cooling is not included.

  The test method, conditions, and evaluation are the same as in Test Example 2. The pest control agent of Example 8 contains LPG as a propellant and cis-1,1,1,4,4,4-hexafluoro-2-butene, and does not contain HFO-1234ze. LPG (LPG0.28) is 228.79 ml, cis-1,1,1,4,4,4-hexafluoro-2-butene is 1.21 ml (0.74 w / v%), and the total is 230 ml. is there.

  Since LPG has a lower cooling effect when attached to the pest 2 than DME, it was predicted that the action inhibiting effect would be lower than in Examples 1 to 7 of Test Examples 1 and 2, but cis-1, Since 1,1,4,4,4-hexafluoro-2-butene has a high action inhibition effect, it can be seen that an effect can be obtained against each pest 2. The propellant is not essential because a sufficient action-inhibiting effect can be obtained even if LPG having a low cooling effect on the pest 2 is used as the propellant. Particularly for moths, a very high effect was obtained even with an extremely short injection time of 2 seconds.

  In addition, since Example 8 does not contain HFO-1234ze, it was predicted that the action-inhibiting effect would be lower than in Examples 1 to 7 of Test Examples 1 and 2, but cis-1,1,1, It can be seen that the action-inhibiting effect of 4,4,4-hexafluoro-2-butene is high, and therefore an effect can be obtained against each pest 2. Therefore, the alternative CFC for cooling is not essential. In other words, the pest control agent only needs to contain at least cis-1,1,1,4,4,4-hexafluoro-2-butene, and does not need to contain an alternative CFC for cooling or a propellant. Are more preferably included.

(Test Example 4)
Test Example 4 confirms the efficacy of Example 9 containing cis-1,1,1,4,4,4-hexafluoro-2-butene and HFO-1234ze and no LPG or dimethyl ether. It is a test for.

  The test method, conditions, and evaluation are the same as in Test Example 2. Example 9 utilizes the injection action of cis-1,1,1,4,4,4-hexafluoro-2-butene and HFO-1234ze without using a propellant such as LPG and dimethyl ether. The components are attached to the pest 2. cis-1,1,1,4,4,4-hexafluoro-2-butene is 1.21 ml (0.74 w / v%), HFO-1234ze is 228.79 ml, and the total is 230 ml. .. HFO-1234ze acts as a propellant and a coolant. On the other hand, Comparative Example 2 is composed only of HFO-1234ze.

  DME has a cooling effect when it adheres to the pest 2, but in this Example 9, it was predicted that the action-inhibiting effect would decrease because it does not contain DME. However, due to the synergistic effect of the action-inhibiting effect of cis-1,1,1,4,4,4-hexafluoro-2-butene and the cooling effect of the insect pest 2 by HFO-1234ze, a high effect on each insect pest 2 is obtained. It can be seen that Therefore, propellants such as LPG and dimethyl ether are not essential. In particular, for the moths, lice, and spiders, a very high effect was obtained even with an extremely short injection time of 2 to 3 seconds.

  In addition, in Examples 1 to 7 and 9, the case of containing HFO-1234ze was illustrated, but instead of HFO-1234ze, another alternative CFC for cooling, for example, HFC-152a, HFC-134a, HFO-1234yf. The same behavior inhibition effect can be obtained even in the case of the above because the heat of vaporization when attached to a pest is similar.

  The above-described embodiments are merely examples in all respects, and should not be limitedly interpreted. Furthermore, all modifications and changes belonging to the equivalent scope of the claims are within the scope of the present invention.

  As described above, the pest control agent according to the present invention can be used for controlling pests such as cockroaches.

1 Aerosol container 1a Container body 1b Head cap 1c Nozzle

Claims (2)

In the pest control agent to be attached to pests,
cis-1,1,1,4,4,4-hexafluoro-2-butene,
An insect pest control agent comprising hydrofluorocarbon and / or hydrofluoroolefin, which is an alternative CFC for cooling. The pest control agent according to claim 1,
An alternative CFC for cooling selected from 1,1-difluoroethane, 1,1,1,2-tetrafluoroethane, 2,3,3,3-tetrafluoropropene and 1,3,3,3-tetrafluoropropene A pest control agent comprising:

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