JP2019537434A5 - - Google Patents

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Publication number
JP2019537434A5
JP2019537434A5 JP2019519212A JP2019519212A JP2019537434A5 JP 2019537434 A5 JP2019537434 A5 JP 2019537434A5 JP 2019519212 A JP2019519212 A JP 2019519212A JP 2019519212 A JP2019519212 A JP 2019519212A JP 2019537434 A5 JP2019537434 A5 JP 2019537434A5
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JP
Japan
Prior art keywords
seq
inhibitor
atp
sample
luciferase
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JP2019519212A
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English (en)
Japanese (ja)
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JP2019537434A (ja
JP7175881B2 (ja
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Priority claimed from PCT/US2017/056571 external-priority patent/WO2018071807A2/en
Publication of JP2019537434A publication Critical patent/JP2019537434A/ja
Publication of JP2019537434A5 publication Critical patent/JP2019537434A5/ja
Priority to JP2022162232A priority Critical patent/JP7615100B2/ja
Application granted granted Critical
Publication of JP7175881B2 publication Critical patent/JP7175881B2/ja
Active legal-status Critical Current
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JP2019519212A 2016-10-13 2017-10-13 ルシフェリン分解産物による阻害に対して改善された耐性を持つ熱安定性ルシフェラーゼ Active JP7175881B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2022162232A JP7615100B2 (ja) 2016-10-13 2022-10-07 ルシフェリン分解産物による阻害に対して改善された耐性を持つ熱安定性ルシフェラーゼ

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662407815P 2016-10-13 2016-10-13
US62/407,815 2016-10-13
PCT/US2017/056571 WO2018071807A2 (en) 2016-10-13 2017-10-13 Thermal stable luciferase with improved resistance to inhibition by luciferin break-down products

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2022162232A Division JP7615100B2 (ja) 2016-10-13 2022-10-07 ルシフェリン分解産物による阻害に対して改善された耐性を持つ熱安定性ルシフェラーゼ

Publications (3)

Publication Number Publication Date
JP2019537434A JP2019537434A (ja) 2019-12-26
JP2019537434A5 true JP2019537434A5 (https=) 2020-11-26
JP7175881B2 JP7175881B2 (ja) 2022-11-21

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ID=61905997

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2019519212A Active JP7175881B2 (ja) 2016-10-13 2017-10-13 ルシフェリン分解産物による阻害に対して改善された耐性を持つ熱安定性ルシフェラーゼ
JP2022162232A Active JP7615100B2 (ja) 2016-10-13 2022-10-07 ルシフェリン分解産物による阻害に対して改善された耐性を持つ熱安定性ルシフェラーゼ

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2022162232A Active JP7615100B2 (ja) 2016-10-13 2022-10-07 ルシフェリン分解産物による阻害に対して改善された耐性を持つ熱安定性ルシフェラーゼ

Country Status (4)

Country Link
US (1) US11261478B2 (https=)
EP (1) EP3526343B1 (https=)
JP (2) JP7175881B2 (https=)
WO (1) WO2018071807A2 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019236731A1 (en) * 2018-06-05 2019-12-12 Promega Corporation Luciferase enzymes for use with thermostable luciferins in bioluminescent assays
US11596895B2 (en) 2020-07-17 2023-03-07 Air Products And Chemicals, Inc. Radial adsorber, adsorption system, and adsorption methods
JPWO2024158050A1 (https=) 2023-01-27 2024-08-02
CN117925547B (zh) * 2023-08-01 2024-10-11 上海碧云天生物技术股份有限公司 经改造的萤火虫萤光素酶、其制备方法及应用

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1978091A1 (en) * 1994-01-03 2008-10-08 Promega Corporation Mutant luciferases
GB9707486D0 (en) * 1997-04-11 1997-05-28 Secr Defence Enzyme assays
US6602677B1 (en) 1997-09-19 2003-08-05 Promega Corporation Thermostable luciferases and methods of production
JP3749628B2 (ja) * 1997-12-26 2006-03-01 キッコーマン株式会社 ルシフェラーゼおよびそれを用いる細胞内ａｔｐの測定法
GB9823468D0 (en) * 1998-10-28 1998-12-23 Secr Defence Novel enzyme
US7192729B2 (en) * 1999-07-06 2007-03-20 General Atomics Methods for assaying homocysteine
US7083911B2 (en) 2001-02-16 2006-08-01 Promega Corporation Method for detection of ATP
US7183092B2 (en) * 2003-10-03 2007-02-27 Board Of Control Of Michigan Technological University Modified luciferase
DE102006054562A1 (de) * 2006-11-20 2008-05-21 Bayer Healthcare Ag Verfahren zum Nachweis von Pyrophosphat mit Biolumineszenz Detektion
JP5188771B2 (ja) * 2007-09-26 2013-04-24 株式会社日立製作所 変異型ホタルルシフェラーゼ
JPWO2009066673A1 (ja) * 2007-11-20 2011-04-07 キッコーマン株式会社 核酸分析用組成物
WO2009140662A1 (en) * 2008-05-15 2009-11-19 Illumina, Inc. Engineered luciferases
US8735559B2 (en) 2010-05-11 2014-05-27 Promega Corporation Mutant protease biosensors with enhanced detection characteristics
WO2012109470A2 (en) * 2011-02-09 2012-08-16 University Of Massachusetts Mutant luciferases
US10241109B2 (en) 2013-11-08 2019-03-26 Mcmaster University Method of stabilizing molecules without refrigeration using water soluble polymers and applications thereof in performing chemical reactions

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