JP2019536015A - 良性腫瘍ではなく悪性腫瘍を標的とし、かつ結合する検出可能な分子 - Google Patents

良性腫瘍ではなく悪性腫瘍を標的とし、かつ結合する検出可能な分子 Download PDF

Info

Publication number
JP2019536015A
JP2019536015A JP2019523046A JP2019523046A JP2019536015A JP 2019536015 A JP2019536015 A JP 2019536015A JP 2019523046 A JP2019523046 A JP 2019523046A JP 2019523046 A JP2019523046 A JP 2019523046A JP 2019536015 A JP2019536015 A JP 2019536015A
Authority
JP
Japan
Prior art keywords
target
tumors
bind
benign
tumor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2019523046A
Other languages
English (en)
Japanese (ja)
Other versions
JP2019536015A5 (enExample
Inventor
ジェンセン、スティーブン、ディー．
Original Assignee
カオ グループ、インク．
カオ グループ、インク．
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by カオ グループ、インク．, カオ グループ、インク． filed Critical カオ グループ、インク．
Publication of JP2019536015A publication Critical patent/JP2019536015A/ja
Publication of JP2019536015A5 publication Critical patent/JP2019536015A5/ja
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/006—Biological staining of tissues in vivo, e.g. methylene blue or toluidine blue O administered in the buccal area to detect epithelial cancer cells, dyes used for delineating tissues during surgery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/70—Mechanisms involved in disease identification
    • G01N2800/7023—(Hyper)proliferation
    • G01N2800/7028—Cancer

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Physics & Mathematics (AREA)
  • Surgery (AREA)
  • Molecular Biology (AREA)
  • Medical Informatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pathology (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Optics & Photonics (AREA)
  • Biophysics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
JP2019523046A 2016-10-26 2017-10-25 良性腫瘍ではなく悪性腫瘍を標的とし、かつ結合する検出可能な分子 Pending JP2019536015A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662412948P 2016-10-26 2016-10-26
US62/412,948 2016-10-26
PCT/US2017/058276 WO2018081262A1 (en) 2016-10-26 2017-10-25 Detectable molecules that target and bind to malignant tumors and not benign tumors

Publications (2)

Publication Number Publication Date
JP2019536015A true JP2019536015A (ja) 2019-12-12
JP2019536015A5 JP2019536015A5 (enExample) 2020-10-08

Family

ID=62025452

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2019523046A Pending JP2019536015A (ja) 2016-10-26 2017-10-25 良性腫瘍ではなく悪性腫瘍を標的とし、かつ結合する検出可能な分子

Country Status (4)

Country Link
US (1) US20190255195A1 (enExample)
JP (1) JP2019536015A (enExample)
CN (1) CN109982721A (enExample)
WO (1) WO2018081262A1 (enExample)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040047804A1 (en) * 1998-10-29 2004-03-11 The General Hospital Corporation, A Massachusetts Corporation Enhanced radiation therapy

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9678059B2 (en) * 2010-05-23 2017-06-13 Technion Research & Development Foundation Ltd. Detection, staging and grading of benign and malignant tumors
CN102372771A (zh) * 2010-08-26 2012-03-14 杨静雯 一种肿瘤靶向分子及其应用
US10106778B2 (en) * 2012-11-08 2018-10-23 Whitehead Institute For Biomedical Research Selective targeting of cancer stem cells
CN104892820B (zh) * 2015-05-11 2017-08-04 厦门大学 一种受体类分子靶向显像剂及其制备方法

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040047804A1 (en) * 1998-10-29 2004-03-11 The General Hospital Corporation, A Massachusetts Corporation Enhanced radiation therapy

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
JARED J BARROTT: "Optical and radioiodinated tethered Hsp90 inhibitors reveal selective internalization of ectopic Hsp", CHEM BIOL, vol. 20, no. 9, JPN6021029746, 19 September 2013 (2013-09-19), pages 1187 - 1197, XP093019223, ISSN: 0004721789, DOI: 10.1016/j.chembiol.2013.08.004 *

Also Published As

Publication number Publication date
CN109982721A (zh) 2019-07-05
US20190255195A1 (en) 2019-08-22
WO2018081262A1 (en) 2018-05-03

Similar Documents

Publication Publication Date Title
D'amato et al. Update on the biology and therapy of gastrointestinal stromal tumors
Zhang et al. PET/CT in the diagnosis and prognosis of osteosarcoma
Logrono et al. Recent Advances in Cell Biology, Diagnosis and Therapy of Gastrointestinal Stroma Tumor (GIST)
Georgescu et al. Correlations of proliferation markers, p53 expression and histological findings in colorectal carcinoma
JP2017121233A5 (enExample)
JP2019144254A (ja) Ｐｓｍａ上昇により致死性前立腺癌が同定される
Bruggink et al. Current role of imaging in diagnosing aortic graft infections
Campennì et al. Association of parathyroid carcinoma and thyroid disorders: A clinical review
Sweet et al. Infiltrative renal malignancies: imaging features, prognostic implications, and mimics
EP3291839A1 (en) Anti-nucleolin agent-conjugated nanoparticles as radio-sensitizers and mri and/or x-ray contrast agents
Nyström et al. A genetically encoded magnetic resonance imaging reporter enables sensitive detection and tracking of spontaneous metastases in deep tissues
WO2013166153A2 (en) Methods and compositions for cancer diagnosis
JP2019536015A (ja) 良性腫瘍ではなく悪性腫瘍を標的とし、かつ結合する検出可能な分子
Ferguson Advances in the adjuvant treatment of infantile fibrosarcoma
Rosa et al. Colorectal cancer patients before resection of hepatic metastases
Hou et al. Evaluation of galactography for nipple discharge
Koide et al. Exfoliated cancer cells during intersphincteric resection for very low rectal cancer
Han et al. Imaging techniques for minimally invasive thoracic surgery—Korea University Guro Hospital experiences
Shim et al. Use of laparoscopy as an alternative to computed tomography (CT) and positron emission tomography (PET) scans for the detection of recurrence in patients with gastric cancer: a pilot study
Nakajo et al. Clinical significance of primary lesion FDG uptake for choice between oesophagectomy and endoscopic submucosal dissection for resectable oesophageal squamous cell carcinomas
Marcheix et al. Lung metastases of diffuse giant cell tumour of the fibular tendon sheath at the ankle: a case report
Lazarioti et al. Diagnostic and Therapeutic Efficacy of Imaging Modalities in Non-Small Cell Lung Cancer (NSCLC): experience from a Phase III clinical study using tumor targeted Lipoplatin nanoparticles
Chen Hodgkin lymphoma
Yan et al. Aggressive Primary Pericardial Mesothelioma: A Case Report and Review of the Literature
Wang et al. Surgical Guidance of Head and Neck Squamous Cell Carcinoma Enabled by a c-MET-Targeting Fluorescent Probe cMBP-ICG

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20200828

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20200828

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20210730

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20210803

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20220308