JP2019529481A - 胆汁酸誘導体の結晶形態 - Google Patents
胆汁酸誘導体の結晶形態 Download PDFInfo
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Classifications
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- C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
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- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
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- A—HUMAN NECESSITIES
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- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
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- Diabetes (AREA)
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- Gastroenterology & Hepatology (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
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| Application Number | Priority Date | Filing Date | Title |
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| US201662402813P | 2016-09-30 | 2016-09-30 | |
| US62/402,813 | 2016-09-30 | ||
| PCT/US2017/054227 WO2018064441A1 (en) | 2016-09-30 | 2017-09-29 | Crystalline forms of a bile acid derivative |
Publications (2)
| Publication Number | Publication Date |
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| JP2019529481A true JP2019529481A (ja) | 2019-10-17 |
| JP2019529481A5 JP2019529481A5 (cg-RX-API-DMAC7.html) | 2020-09-17 |
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| KR (1) | KR20190057108A (cg-RX-API-DMAC7.html) |
| CN (1) | CN109963567A (cg-RX-API-DMAC7.html) |
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| BR (1) | BR112019006242A2 (cg-RX-API-DMAC7.html) |
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| MX (1) | MX2019003684A (cg-RX-API-DMAC7.html) |
| WO (1) | WO2018064441A1 (cg-RX-API-DMAC7.html) |
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| IL291985A (en) | 2019-10-07 | 2022-06-01 | Kallyope Inc | Gpr119 agonists |
| PH12022552277A1 (en) | 2020-02-28 | 2024-03-04 | Kallyope Inc | Gpr40 agonists |
| UY39222A (es) | 2020-05-19 | 2021-11-30 | Kallyope Inc | Activadores de la ampk |
| EP4172162A4 (en) | 2020-06-26 | 2024-08-07 | Kallyope, Inc. | AMPK ACTIVATORS |
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| EP2040713B1 (en) * | 2006-06-27 | 2014-06-18 | Intercept Pharmaceuticals Inc. | Bile acid derivatives as fxr ligands for the prevention or treatment of fxr-mediated deseases or conditions |
| KR20090066297A (ko) * | 2006-10-16 | 2009-06-23 | 화이자 프로덕츠 인크. | 치료용 피라졸릴 티에노피리딘 |
| US8329691B2 (en) * | 2007-10-15 | 2012-12-11 | Takeda Pharmaceutical Company Limited | Amide compounds and use of the same |
| EP2468762A1 (en) * | 2010-11-30 | 2012-06-27 | Dr. Falk Pharma Gmbh | Optimized synthesis of pure, non-polymorphic, crystalline bile acids with defined particle size |
| CN104781272A (zh) * | 2012-06-19 | 2015-07-15 | 英特塞普特医药品公司 | 奥贝胆酸的制备、用途和固体形式 |
| US9777038B2 (en) * | 2012-10-26 | 2017-10-03 | Intercept Pharmaceuticals, Inc. | Process for preparing bile acid derivatives |
| AU2013352288B2 (en) * | 2012-11-28 | 2017-11-23 | Intercept Pharmaceuticals, Inc. | Treatment of pulmonary disease |
| HUP1300504A2 (en) * | 2013-08-27 | 2015-03-30 | Egis Gyogyszergyar Nyilvanosan Muekoedoe Reszvenytarsasag | Sorafenib salts |
| AU2016306297A1 (en) * | 2015-08-07 | 2018-02-22 | Intercept Pharmaceuticals, Inc. | Methods for preparation of bile acids and derivatives thereof |
| CN108350020A (zh) * | 2015-09-24 | 2018-07-31 | 英特塞普特医药品公司 | 用于制备胆汁酸衍生物的方法和中间体 |
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2017
- 2017-09-29 CN CN201780071347.7A patent/CN109963567A/zh active Pending
- 2017-09-29 MX MX2019003684A patent/MX2019003684A/es unknown
- 2017-09-29 EP EP17857474.5A patent/EP3518937A4/en not_active Withdrawn
- 2017-09-29 JP JP2019516972A patent/JP2019529481A/ja not_active Withdrawn
- 2017-09-29 US US16/337,982 patent/US20200024299A1/en not_active Abandoned
- 2017-09-29 BR BR112019006242A patent/BR112019006242A2/pt not_active IP Right Cessation
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- 2017-09-29 CA CA3038534A patent/CA3038534A1/en not_active Abandoned
- 2017-09-29 AU AU2017336803A patent/AU2017336803A1/en not_active Abandoned
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2019
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Also Published As
| Publication number | Publication date |
|---|---|
| EP3518937A4 (en) | 2020-04-29 |
| IL265621A (en) | 2019-05-30 |
| AU2017336803A1 (en) | 2019-04-18 |
| BR112019006242A2 (pt) | 2019-06-18 |
| MX2019003684A (es) | 2019-08-05 |
| WO2018064441A1 (en) | 2018-04-05 |
| CN109963567A (zh) | 2019-07-02 |
| US20200024299A1 (en) | 2020-01-23 |
| CA3038534A1 (en) | 2018-04-05 |
| EP3518937A1 (en) | 2019-08-07 |
| KR20190057108A (ko) | 2019-05-27 |
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