JP2019523633A - 組織の損傷に関連した疾患及び障害を予防及び治療する組織保護ペプチド - Google Patents

組織の損傷に関連した疾患及び障害を予防及び治療する組織保護ペプチド Download PDF

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JP2019523633A
JP2019523633A JP2018556357A JP2018556357A JP2019523633A JP 2019523633 A JP2019523633 A JP 2019523633A JP 2018556357 A JP2018556357 A JP 2018556357A JP 2018556357 A JP2018556357 A JP 2018556357A JP 2019523633 A JP2019523633 A JP 2019523633A
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cancer
disease
peptide
peptides
cell
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JP2019523633A5 (https=
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ブリネス マイケル
ブリネス マイケル
セラミ アンソニイ
セラミ アンソニイ
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アライム ファーマシューティカルズ，インコーポレーテッド
アライム ファーマシューティカルズ，インコーポレーテッド
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/1008—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Pain & Pain Management (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Rheumatology (AREA)
  • Toxicology (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP2018556357A 2016-04-29 2017-04-28 組織の損傷に関連した疾患及び障害を予防及び治療する組織保護ペプチド Pending JP2019523633A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662329743P 2016-04-29 2016-04-29
US62/329,743 2016-04-29
PCT/US2017/030100 WO2017189988A1 (en) 2016-04-29 2017-04-28 Tissue protective peptides for preventing and treating diseases and disorders associated with tissue damage

Publications (2)

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JP2019523633A true JP2019523633A (ja) 2019-08-29
JP2019523633A5 JP2019523633A5 (https=) 2020-06-18

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JP2018556357A Pending JP2019523633A (ja) 2016-04-29 2017-04-28 組織の損傷に関連した疾患及び障害を予防及び治療する組織保護ペプチド

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Country Link
US (1) US10864253B2 (https=)
EP (1) EP3448415A4 (https=)
JP (1) JP2019523633A (https=)
CN (1) CN109310741A (https=)
WO (1) WO2017189988A1 (https=)

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AU2020245535B2 (en) * 2019-03-26 2022-06-30 Pinova Therapeutics Inc. Devices and methods for delivering pharmaceutical compositions
US12377112B2 (en) * 2019-04-17 2025-08-05 Compass Pathfinder Limited Methods of treating neurocognitive disorders, chronic pain and reducing inflammation
BR112022009955A2 (pt) * 2019-12-13 2022-08-09 Massachusetts Inst Technology Barreiras de tecido sintético e seus usos
EP4276105A4 (en) * 2021-01-11 2024-12-18 Sichuan Gooddoctor Panxi Pharmaceutical Co. Ltd POLYPEPTIDE FOR REPAIRING A SKIN WOUND OR A MUCOSAL INJURY, AND ITS USE
CN119908970B (zh) * 2025-01-23 2026-02-03 诺德溯源(广州)生物科技有限公司 一种用于改善女性更年期衰老的护肤组合物及其应用

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US20070060519A1 (en) * 2004-01-28 2007-03-15 Johannes Rozing Hsp therapy in conjunction with a low antigenicity diet
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US20110212105A1 (en) * 2006-04-28 2011-09-01 Vivian Huerta Galindo Method to block the infection by flaviviruses, molecules and uses
CA2940078A1 (en) * 2014-03-03 2015-09-11 Centro De Ingenieria Genetica Y Biotecnologia Beta hairpin peptides having anti-viral properties against the dengue virus

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US20090202618A1 (en) * 2003-11-24 2009-08-13 Yeda Research & Development Co. Ltd Dna vaccines encoding hsp60 peptide fragments for treating autoimmune diseases
US20070060519A1 (en) * 2004-01-28 2007-03-15 Johannes Rozing Hsp therapy in conjunction with a low antigenicity diet
US20110212105A1 (en) * 2006-04-28 2011-09-01 Vivian Huerta Galindo Method to block the infection by flaviviruses, molecules and uses
CA2940078A1 (en) * 2014-03-03 2015-09-11 Centro De Ingenieria Genetica Y Biotecnologia Beta hairpin peptides having anti-viral properties against the dengue virus

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WO2017189988A8 (en) 2018-01-25
EP3448415A1 (en) 2019-03-06
EP3448415A4 (en) 2019-11-06
US20190134156A1 (en) 2019-05-09
CN109310741A (zh) 2019-02-05
US10864253B2 (en) 2020-12-15
WO2017189988A1 (en) 2017-11-02

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