JP2019520332A - Ｃｍｖエピトープ - Google Patents

Ｃｍｖエピトープ Download PDF

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Publication number
JP2019520332A
JP2019520332A JP2018561467A JP2018561467A JP2019520332A JP 2019520332 A JP2019520332 A JP 2019520332A JP 2018561467 A JP2018561467 A JP 2018561467A JP 2018561467 A JP2018561467 A JP 2018561467A JP 2019520332 A JP2019520332 A JP 2019520332A
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JP
Japan
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subject
apc
cmv
cell
cells
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Pending
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JP2018561467A
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English (en)
Japanese (ja)
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JP2019520332A5 (enExample
Inventor
カンナ，ラジーブ
スミス，コーリー
Original Assignee
ザ カウンシル オブ ザ クイーンズランド インスティテュート オブ メディカル リサーチ
ザ カウンシル オブ ザ クイーンズランド インスティテュート オブ メディカル リサーチ
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Application filed by ザ カウンシル オブ ザ クイーンズランド インスティテュート オブ メディカル リサーチ, ザ カウンシル オブ ザ クイーンズランド インスティテュート オブ メディカル リサーチ filed Critical ザ カウンシル オブ ザ クイーンズランド インスティテュート オブ メディカル リサーチ
Publication of JP2019520332A publication Critical patent/JP2019520332A/ja
Publication of JP2019520332A5 publication Critical patent/JP2019520332A5/ja
Priority to JP2023020200A priority Critical patent/JP2023071724A/ja
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/46—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A61K2039/572—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 cytotoxic response
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16111—Cytomegalovirus, e.g. human herpesvirus 5
    • C12N2710/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16111—Cytomegalovirus, e.g. human herpesvirus 5
    • C12N2710/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mycology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP2018561467A 2016-05-23 2017-05-23 Ｃｍｖエピトープ Pending JP2019520332A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2023020200A JP2023071724A (ja) 2016-05-23 2023-02-13 Ｃｍｖエピトープ

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662340223P 2016-05-23 2016-05-23
US62/340,223 2016-05-23
PCT/IB2017/000849 WO2017203370A2 (en) 2016-05-23 2017-05-23 Cmv epitopes

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2023020200A Division JP2023071724A (ja) 2016-05-23 2023-02-13 Ｃｍｖエピトープ

Publications (2)

Publication Number Publication Date
JP2019520332A true JP2019520332A (ja) 2019-07-18
JP2019520332A5 JP2019520332A5 (enExample) 2020-07-02

Family

ID=60412168

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2018561467A Pending JP2019520332A (ja) 2016-05-23 2017-05-23 Ｃｍｖエピトープ
JP2023020200A Pending JP2023071724A (ja) 2016-05-23 2023-02-13 Ｃｍｖエピトープ

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2023020200A Pending JP2023071724A (ja) 2016-05-23 2023-02-13 Ｃｍｖエピトープ

Country Status (7)

Country Link
US (2) US20200316119A1 (enExample)
EP (1) EP3463400A4 (enExample)
JP (2) JP2019520332A (enExample)
CN (1) CN109475579A (enExample)
AU (2) AU2017271136A1 (enExample)
CA (1) CA3025234A1 (enExample)
WO (1) WO2017203370A2 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2023526766A (ja) * 2020-04-28 2023-06-23 ザ・カウンシル・オヴ・ザ・クイーンズランド・インスティテュート・オヴ・メディカル・リサーチ ヒトサイトメガロウイルスポリエピトープワクチン組成物

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2018346719A1 (en) 2017-10-06 2020-04-23 Oslo Universitetssykehus Hf Chimeric antigen receptors
US20210393684A1 (en) * 2018-05-18 2021-12-23 The Council Of The Queensland Institute Of Medical Research (Qimr) Adoptive T-Cell Therapy for CMV Infection and CMV-Associated Diseases
MX2021002702A (es) 2018-09-10 2021-05-12 Atara Biotherapeutics Inc Metodos para expandir celulas t del receptor de antigeno quimerico especificas de antigenos, composiciones y usos relacionados con las mismas.
CN114787190A (zh) * 2019-10-09 2022-07-22 昆士兰医学研究所理事会 靶向epha3及其用途
CN111875698B (zh) * 2020-07-29 2021-11-05 广州呈源生物免疫技术有限公司 靶向hcmv的tcr及其获得方法和应用

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003501076A (ja) * 1999-06-04 2003-01-14 フロリアン・ケルン ヒトｃｍｖに対するワクチン接種のためのペプチド
WO2010037397A1 (en) * 2008-10-01 2010-04-08 Dako Denmark A/S Mhc multimers in cmv immune monitoring

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Publication number Priority date Publication date Assignee Title
DE10009341A1 (de) * 2000-02-22 2001-09-06 Florian Kern Verfahren zur antigen-spezifischen Stimulation von T-Lymphozyten
WO2003008537A2 (en) * 2001-04-06 2003-01-30 Mannkind Corporation Epitope sequences
AUPR593101A0 (en) * 2001-06-26 2001-07-19 Council Of The Queensland Institute Of Medical Research, The Cytomegalovirus t cell epitopes
EP1651666B1 (en) * 2003-07-11 2009-05-27 Alphavax, Inc. Alphavirus-based cytomegalovirus vaccines
AU2012227280B2 (en) * 2004-11-29 2016-09-22 The Council Of The Queensland Institute Of Medical Research Human cytomegalovirus immunotherapy
US7976845B2 (en) * 2004-11-29 2011-07-12 The Council Of The Queensland Institute Of Medical Research Human cytomegalovirus immunotherapy
TW201000119A (en) * 2008-06-10 2010-01-01 Oncotherapy Science Inc MYBL2 epitope peptides and vaccines containing the same
EP2313503A4 (en) * 2008-08-01 2014-01-08 Merck Sharp & Dohme Variant HCMV-PP65, IE1 and IE2 polynucleotides, and uses thereof
GB0917094D0 (en) * 2009-09-29 2009-11-11 Ucl Biomedica Plc T-cell receptor
ES2928851T3 (es) * 2012-02-09 2022-11-23 Baylor College Medicine Mezclas pep para generar CTL multivíricos con amplia especificidad
US9585952B2 (en) * 2012-05-16 2017-03-07 Adelaide Research & Innovation Pty Ltd Cellular vaccine and method of inducing an immune response in a subject
GB201312133D0 (en) * 2013-07-05 2013-08-21 Univ Birmingham Immunotherapy
WO2015142671A2 (en) * 2014-03-17 2015-09-24 Flugen, Inc. Influenza virus vectors and uses therefor

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003501076A (ja) * 1999-06-04 2003-01-14 フロリアン・ケルン ヒトｃｍｖに対するワクチン接種のためのペプチド
WO2010037397A1 (en) * 2008-10-01 2010-04-08 Dako Denmark A/S Mhc multimers in cmv immune monitoring

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
JDI, 2007, VOL.195, PP,1789-1798, JPN6022006768, ISSN: 0005054160 *
JOURNAL OF VIROLOGY, 1999, VOL.73, NO.10, PP.8179-8184, JPN6022006770, ISSN: 0005054161 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2023526766A (ja) * 2020-04-28 2023-06-23 ザ・カウンシル・オヴ・ザ・クイーンズランド・インスティテュート・オヴ・メディカル・リサーチ ヒトサイトメガロウイルスポリエピトープワクチン組成物

Also Published As

Publication number Publication date
WO2017203370A3 (en) 2018-02-01
EP3463400A2 (en) 2019-04-10
AU2023201279A1 (en) 2023-04-20
WO2017203370A2 (en) 2017-11-30
CN109475579A (zh) 2019-03-15
AU2017271136A1 (en) 2019-01-03
JP2023071724A (ja) 2023-05-23
US20200316119A1 (en) 2020-10-08
EP3463400A4 (en) 2020-07-29
CA3025234A1 (en) 2017-11-30
US20250127874A1 (en) 2025-04-24

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