JP2019517321A - 薬剤送達装置 - Google Patents
薬剤送達装置 Download PDFInfo
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- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
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- A61M5/178—Syringes
- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31501—Means for blocking or restricting the movement of the rod or piston
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- A—HUMAN NECESSITIES
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- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31535—Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose
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- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
- A61M5/31566—Means improving security or handling thereof
- A61M5/31571—Means preventing accidental administration
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- A—HUMAN NECESSITIES
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- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
- A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
- A61M5/31578—Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/3202—Devices for protection of the needle before use, e.g. caps
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/3202—Devices for protection of the needle before use, e.g. caps
- A61M5/3204—Needle cap remover, i.e. devices to dislodge protection cover from needle or needle hub, e.g. deshielding devices
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/3205—Apparatus for removing or disposing of used needles or syringes, e.g. containers; Means for protection against accidental injuries from used needles
- A61M5/321—Means for protection against accidental injuries by used needles
- A61M5/3243—Means for protection against accidental injuries by used needles being axially-extensible, e.g. protective sleeves coaxially slidable on the syringe barrel
- A61M5/3257—Semi-automatic sleeve extension, i.e. in which triggering of the sleeve extension requires a deliberate action by the user, e.g. manual release of spring-biased extension means
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
- A61M2005/2006—Having specific accessories
- A61M2005/2013—Having specific accessories triggering of discharging means by contact of injector with patient body
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
- A61M2005/2073—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically preventing premature release, e.g. by making use of a safety lock
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
- A61M2005/2073—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically preventing premature release, e.g. by making use of a safety lock
- A61M2005/208—Release is possible only when device is pushed against the skin, e.g. using a trigger which is blocked or inactive when the device is not pushed against the skin
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Abstract
Description
本発明は、たとえば硬い表面上への装置の落下後であっても、影響を受けない装置を保証する安全機構を備える薬剤送達装置に関する。
特に装置が患者自身によって手持ちされることがますます意図されるため、今日、市場における多くの薬剤送達装置には、装置の使用を容易にするだろう多数の機構を設けられる。追加された機能性はまた、薬剤送達装置が注射針を備えるときに有利である。これは、多くの患者は針を見て不快に感じ、また針の侵入に関して気乗りしないように感じるためである。それに関して、いくつかの構成に言及すれば、自動侵入機構および自動注入機構などの追加された機能である。
本願では、用語「遠位部分/端部」が用いられるとき、これは装置の使用下において患者の薬剤送達位置から最も離れて位置する、装置の部分/端部、または、その部材の部分/端部を意味する。これに対応して、用語「近位部分/端部」が用いられるとき、これは装置の使用下において患者の薬剤送達位置に対して最も近くに位置する、装置の部分/端部、または、その部材の部分/端部を意味する。
図面に示される実施形態は、断面がやや三角形状であり、遠位端部12および近位端部14を有する、概ね細長い管状の筐体10、図1、を備える。筐体は、活性化の際、たとえば注射針20、図3、などの薬剤送達部材を介して、筐体内部に配置される薬剤容器18から用量の薬剤の送達をもたらすことが可能な薬剤送達活性化機構16、図2、を収容するように設けられる。注射針は、使用前には適切な薬剤送達部材シールド22、図2、によって保護され得、示される実施形態では、いわゆるRNS(rigid needle shield(剛性針シールド))が用いられる。薬剤送達活性化機構は、本発明に必須ではない多数の設計および機能を有し得るため、詳細には説明されない。
Claims (10)
- 薬剤送達装置であって、
近位端部および遠位端部を有する、概ね細長い筐体(10,24)と、
活性化の際、薬剤容器(18)から用量の薬剤を送達することが可能な、薬剤送達活性化機構(16)と、
薬剤送達部材(20)に設けられ、前記筐体に配置される、前記薬剤容器(18)と、
前記薬剤送達部材(20)に設けられる、薬剤送達部材シールド(22)と、
前記筐体(10,24)の前記近位端部に移動可能に設けられる、薬剤送達部材ガード(54)と、を備え、前記薬剤送達部材ガード(54)は、前記薬剤送達活性化機構(16)に動作可能に接続されており、前記薬剤送達装置はさらに、
前記筐体の前記近位端部に解放可能に設けられる保護キャップ(42)を備え、
前記保護キャップ(42)には、薬剤送達部材シールド取外し部(50)が設けられ、
前記薬剤送達部材ガード(54)に設けられる阻止要素(58)を特徴とし、
前記阻止要素(58)は、阻止位置と解放位置との間で移動可能に設けられ、
前記阻止要素(58)には、前記筐体の近位領域(68)と係合するように設けられる係合面(62)が設けられ、
前記阻止要素(58)は、前記薬剤送達部材シールド取外し部(50)の表面と係合して前記阻止要素を前記阻止位置に保持するように設けられ、前記係合面(62)の前記近位領域(68)との係合は、前記薬剤送達部材ガード(54)の移動の阻止をもたらし、前記保護キャップ(42)および前記薬剤送達部材シールド取外し部(50)の取外しは、前記係合面(62)が前記近位領域(68)に係合するときに前記阻止要素(58)の解放位置への移動を可能にして前記薬剤送達部材ガード(54)が移動できるようにする、薬剤送達装置。 - 前記阻止要素(58)は、概ね径方向に撓むことのできる部材を備える、請求項1に記載の薬剤送達装置。
- 前記阻止要素(58)は、前記装置の停止面(68)と相互作用する前記係合面(62)が設けられる、可撓性の舌部(60)を備える、請求項2に記載の薬剤送達装置。
- 前記停止面(68)は、前記装置の筐体(24)の近位端部面を備える、請求項3に記載の薬剤送達装置。
- 前記阻止要素(58)には、内側に向けられた接触面(66)が設けられ、前記保護カバー(42)には、前記接触面が係合するところに概ね管状の薬剤送達部材シールド取外し部(50)が設けられ、薬剤送達部材シールド取外し部(50)は、薬剤送達部材シールド(22)を取り囲み、薬剤送達部材シールド(22)と係合する、請求項4に記載の薬剤送達装置。
- 前記薬剤送達部材シールド取外し部(50)は、前記薬剤送達部材シールド(22)の外面を挟持するように設けられる、傾斜した舌部(52)を備える、請求項5に記載の薬剤送達装置。
- 前記薬剤送達部材シールド取外し部(50)は、金属からなる、先行する請求項のいずれか1項に記載の薬剤送達装置。
- 前記保護キャップ(42)を解放可能に保持するように動作可能に設けられる、保護キャップ保持機構(38,46)をさらに備える、先行する請求項のいずれか1項に記載の薬剤送達装置。
- 前記保護キャップ保持機構は、接触面を形成する、前記装置の筐体部分(24)上の少なくとも1つの突出部(38)の形態の第1保持部材を備え、接触面は、前記保護キャップ上の第2保持部材の接触面(46I〜46IV)と協働するように設けられる、請求項8に記載の薬剤送達装置。
- 前記保護キャップは、弾性特性を有する材料で設計され、前記接触面は、前記保護キャップ上の解放力が前記保護キャップを曲げ、前記接触面を互いに接触させないように移動させるように設けられ、これにより前記保護キャップを解放する、請求項9に記載の薬剤送達装置。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
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SE1650778 | 2016-06-03 | ||
SE1650778-2 | 2016-06-03 | ||
PCT/EP2017/060965 WO2017207224A1 (en) | 2016-06-03 | 2017-05-09 | Medicament delivery device |
Publications (2)
Publication Number | Publication Date |
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JP2019517321A true JP2019517321A (ja) | 2019-06-24 |
JP6785319B2 JP6785319B2 (ja) | 2020-11-18 |
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JP2018563126A Active JP6785319B2 (ja) | 2016-06-03 | 2017-05-09 | 薬剤送達装置 |
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US (3) | US11273259B2 (ja) |
EP (3) | EP3463513B1 (ja) |
JP (1) | JP6785319B2 (ja) |
KR (2) | KR102384133B1 (ja) |
CN (2) | CN113304355A (ja) |
CA (1) | CA3065853C (ja) |
DK (2) | DK3622986T3 (ja) |
ES (2) | ES2846925T3 (ja) |
PT (2) | PT3463513T (ja) |
TW (1) | TWI654005B (ja) |
WO (1) | WO2017207224A1 (ja) |
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CH712753A2 (de) | 2016-07-28 | 2018-01-31 | Tecpharma Licensing Ag | Trennen einer Nadelschutzkappe von einem Produktbehälter und Verfahren zum Montieren einer Injektionsvorrichtung. |
EP3801694A4 (en) | 2018-06-08 | 2022-03-16 | Antares Pharma, Inc. | INJECTOR WITH AUTOMATIC INSERTION |
GB2577549B (en) | 2018-09-28 | 2021-08-04 | Owen Mumford Ltd | Injection device with commit feature |
US20220016356A1 (en) * | 2018-12-12 | 2022-01-20 | Shl Medical Ag | Activation prevention cap assembly |
WO2022181448A1 (en) * | 2021-02-24 | 2022-09-01 | Terumo Kabushiki Kaisha | Medication administration device |
KR102569300B1 (ko) * | 2023-03-23 | 2023-08-22 | 주식회사 비에스엘 | 자동 약물 주입 장치의 근위 캡 |
KR102542985B1 (ko) * | 2023-04-10 | 2023-06-14 | 주식회사 비에스엘 | 자동 약물 주입 장치의 바늘 보호 캡 |
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BRPI0910000B8 (pt) | 2008-06-20 | 2021-06-22 | West Pharmaceutical Services Inc | mecanismo de injeção automática com apoio frontal referência cruzada com solicitações relacionadas |
EP2954914B1 (de) | 2009-05-29 | 2018-11-21 | TecPharma Licensing AG | Injektionsvorrichtung, insbesondere autoinjektor mit stechschutz und/oder überlastsicherung für ein produktbehältnis |
CN102639170B (zh) | 2009-09-30 | 2014-10-15 | Shl集团有限责任公司 | 药物输送装置 |
EP2361648A1 (en) * | 2010-02-18 | 2011-08-31 | Sanofi-Aventis Deutschland GmbH | Remover for a protective needle shield |
WO2011145999A1 (en) | 2010-05-20 | 2011-11-24 | Shl Group Ab | Medicament delivery device |
WO2012045350A1 (en) | 2010-10-06 | 2012-04-12 | Tecpharma Licensing Ag | Locking and retaining mechanism for the needle guard sleeve of an injection device |
EP2729203B2 (en) | 2011-07-05 | 2023-09-13 | SHL Group AB | Needle sheath remover assembly |
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EP3628348A1 (en) | 2020-04-01 |
US11273259B2 (en) | 2022-03-15 |
KR102242976B1 (ko) | 2021-04-22 |
CN109310823A (zh) | 2019-02-05 |
CN109310823B (zh) | 2021-05-18 |
US20200046901A1 (en) | 2020-02-13 |
WO2017207224A1 (en) | 2017-12-07 |
TW201808368A (zh) | 2018-03-16 |
DK3463513T3 (da) | 2021-01-25 |
DK3622986T3 (da) | 2021-05-25 |
EP3622986B1 (en) | 2021-03-24 |
KR102384133B1 (ko) | 2022-04-08 |
EP3622986A1 (en) | 2020-03-18 |
ES2846925T3 (es) | 2021-07-30 |
US11191901B2 (en) | 2021-12-07 |
JP6785319B2 (ja) | 2020-11-18 |
US11986635B2 (en) | 2024-05-21 |
ES2874510T3 (es) | 2021-11-05 |
PT3622986T (pt) | 2021-05-31 |
EP3463513B1 (en) | 2020-11-11 |
EP3463513A1 (en) | 2019-04-10 |
US20220152307A1 (en) | 2022-05-19 |
CA3065853A1 (en) | 2017-12-07 |
KR20210044319A (ko) | 2021-04-22 |
US20200324056A1 (en) | 2020-10-15 |
PT3463513T (pt) | 2021-01-29 |
TWI654005B (zh) | 2019-03-21 |
CN113304355A (zh) | 2021-08-27 |
CA3065853C (en) | 2022-03-08 |
KR20190003700A (ko) | 2019-01-09 |
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