JP2019515672A5 - - Google Patents

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Publication number
JP2019515672A5
JP2019515672A5 JP2018554677A JP2018554677A JP2019515672A5 JP 2019515672 A5 JP2019515672 A5 JP 2019515672A5 JP 2018554677 A JP2018554677 A JP 2018554677A JP 2018554677 A JP2018554677 A JP 2018554677A JP 2019515672 A5 JP2019515672 A5 JP 2019515672A5
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Japan
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host cell
amino acid
acid sequence
seq
domain
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JP2018554677A
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Japanese (ja)
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JP2019515672A (ja
JP7198670B2 (ja
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Priority claimed from PCT/US2017/028693 external-priority patent/WO2017184901A1/en
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Publication of JP2019515672A5 publication Critical patent/JP2019515672A5/ja
Priority to JP2022139098A priority Critical patent/JP2022164858A/ja
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Publication of JP7198670B2 publication Critical patent/JP7198670B2/ja
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JP2018554677A 2016-04-20 2017-04-20 免疫調整性il2r融合タンパク質およびその使用 Active JP7198670B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2022139098A JP2022164858A (ja) 2016-04-20 2022-09-01 免疫調整性il2r融合タンパク質およびその使用

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662325428P 2016-04-20 2016-04-20
US62/325,428 2016-04-20
PCT/US2017/028693 WO2017184901A1 (en) 2016-04-20 2017-04-20 Immunomodulatory il2r fusion proteins and uses thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2022139098A Division JP2022164858A (ja) 2016-04-20 2022-09-01 免疫調整性il2r融合タンパク質およびその使用

Publications (3)

Publication Number Publication Date
JP2019515672A JP2019515672A (ja) 2019-06-13
JP2019515672A5 true JP2019515672A5 (cg-RX-API-DMAC7.html) 2020-05-28
JP7198670B2 JP7198670B2 (ja) 2023-01-04

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ID=58710057

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JP2018554677A Active JP7198670B2 (ja) 2016-04-20 2017-04-20 免疫調整性il2r融合タンパク質およびその使用
JP2022139098A Ceased JP2022164858A (ja) 2016-04-20 2022-09-01 免疫調整性il2r融合タンパク質およびその使用

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JP2022139098A Ceased JP2022164858A (ja) 2016-04-20 2022-09-01 免疫調整性il2r融合タンパク質およびその使用

Country Status (7)

Country Link
US (1) US20190127435A1 (cg-RX-API-DMAC7.html)
EP (1) EP3445847B1 (cg-RX-API-DMAC7.html)
JP (2) JP7198670B2 (cg-RX-API-DMAC7.html)
CN (1) CN109312304A (cg-RX-API-DMAC7.html)
CA (1) CA3021455A1 (cg-RX-API-DMAC7.html)
ES (1) ES2981274T3 (cg-RX-API-DMAC7.html)
WO (1) WO2017184901A1 (cg-RX-API-DMAC7.html)

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ES2979088T3 (es) 2015-03-05 2024-09-24 Fred Hutchinson Cancer Center Proteínas de fusión inmunomoduladoras y usos de las mismas
WO2017201432A2 (en) * 2016-05-19 2017-11-23 Jounaidi Youssef Tethered interleukin-2 to its receptor il-2rbeta, a platform to enhance natural killer and regulatory t cell activity
JP2020511136A (ja) * 2017-03-17 2020-04-16 フレッド ハッチンソン キャンサー リサーチ センター 免疫調節性融合タンパク質およびその使用
WO2019052562A1 (zh) * 2017-09-15 2019-03-21 科济生物医药(上海)有限公司 Il-4r的融合蛋白及其应用
CN108504685A (zh) * 2018-03-27 2018-09-07 宜明细胞生物科技有限公司 一种利用CRISPR/Cas9系统同源重组修复IL-2RG缺陷基因的方法
CN110615843B (zh) * 2018-06-20 2023-05-09 上海隆耀生物科技有限公司 一种包含第三信号受体的嵌合抗原受体及其应用
CN110582515A (zh) * 2018-11-12 2019-12-17 天境生物科技(上海)有限公司 包含cd47抗体和细胞因子的融合蛋白
WO2020259707A1 (zh) * 2019-06-28 2020-12-30 科济生物医药(上海)有限公司 抗移植反应的细胞和方法
US20220296644A1 (en) * 2019-09-11 2022-09-22 The Board Of Trustees Of The Leland Stanford Junior University Chimeric orthogonal receptor proteins and methods of use
EP4031583A4 (en) * 2019-09-16 2023-11-15 Fred Hutchinson Cancer Center CHIMERIC RECEPTOR PROTEINS AND THEIR USES
GB201913697D0 (en) * 2019-09-23 2019-11-06 King S College London DAP10/DAP12 fusion polypeptides
US20240122979A1 (en) * 2019-10-08 2024-04-18 Provincial Health Services Authority Chimeric Cytokine Receptors
US20230030680A1 (en) * 2020-01-07 2023-02-02 St. Jude Children's Research Hospital, Inc Chimeric gmcsf-il18 receptor
CN113249330A (zh) * 2021-05-20 2021-08-13 深圳市先康达生命科学有限公司 免疫细胞及其应用
WO2023081727A1 (en) * 2021-11-02 2023-05-11 Fred Hutchinson Cancer Center Treatments for cancers utilizing cell-targeted therapies and associated research protocols
IL322949A (en) 2023-03-03 2025-10-01 Arsenal Biosciences Inc Systems targeting PSMA and CA9
WO2025039159A1 (en) * 2023-08-21 2025-02-27 Hangzhou Hervor Therapeutics Co., Ltd Synthetic cytokine signaling system, preparation method, and uses thereof
WO2025081123A1 (en) 2023-10-12 2025-04-17 Fred Hutchinson Cancer Center Methods and compositions for improving t cell immunotherapy
WO2025085536A1 (en) * 2023-10-16 2025-04-24 Lankenau Institute For Medical Research Biologic conjugates that inhibit production of inflammatory cells and methods of use
CN117511885B (zh) * 2024-01-08 2024-06-11 青岛华赛伯曼医学细胞生物有限公司 提高识别和杀伤肿瘤能力的工程化til细胞及其应用
WO2025245169A1 (en) 2024-05-21 2025-11-27 Fred Hutchinson Cancer Center Immunotherapy cells equipped with a collagen-targeting payload

Family Cites Families (7)

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Publication number Priority date Publication date Assignee Title
US5283173A (en) 1990-01-24 1994-02-01 The Research Foundation Of State University Of New York System to detect protein-protein interactions
EP0693084A4 (en) * 1993-04-06 1999-06-02 Hutchinson Fred Cancer Res CHIMERAL CYTOKINE RECEPTORS IN LYMPHOCYTE
CN1911965B (zh) * 2001-01-17 2013-05-29 新兴产品开发西雅图有限公司 结合域-免疫球蛋白融合蛋白
WO2008042814A2 (en) 2006-09-29 2008-04-10 California Institute Of Technology Mart-1 t cell receptors
US9272002B2 (en) * 2011-10-28 2016-03-01 The Trustees Of The University Of Pennsylvania Fully human, anti-mesothelin specific chimeric immune receptor for redirected mesothelin-expressing cell targeting
EP3594245A1 (en) * 2012-02-13 2020-01-15 Seattle Children's Hospital d/b/a Seattle Children's Research Institute Bispecific chimeric antigen receptors and therapeutic uses thereof
EP2986636B1 (en) * 2013-04-17 2018-11-14 Baylor College Of Medicine Immunosuppressive tgf-beta signal converter

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