JP2019512274A5 - - Google Patents
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- Publication number
- JP2019512274A5 JP2019512274A5 JP2019501754A JP2019501754A JP2019512274A5 JP 2019512274 A5 JP2019512274 A5 JP 2019512274A5 JP 2019501754 A JP2019501754 A JP 2019501754A JP 2019501754 A JP2019501754 A JP 2019501754A JP 2019512274 A5 JP2019512274 A5 JP 2019512274A5
- Authority
- JP
- Japan
- Prior art keywords
- tissue
- composition
- biomolecule
- sample
- use according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 239000000203 mixture Substances 0.000 claims description 37
- 238000005070 sampling Methods 0.000 claims description 25
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 claims description 18
- 238000001514 detection method Methods 0.000 claims description 16
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical group [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims description 12
- 108020004707 nucleic acids Proteins 0.000 claims description 12
- 102000039446 nucleic acids Human genes 0.000 claims description 12
- 150000007523 nucleic acids Chemical class 0.000 claims description 12
- 241000710780 Bovine viral diarrhea virus 1 Species 0.000 claims description 11
- PPBOKXIGFIBOGK-BDTUAEFFSA-N bvdv Chemical compound C([C@@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)C(C)C)[C@@H](C)CC)C1=CN=CN1 PPBOKXIGFIBOGK-BDTUAEFFSA-N 0.000 claims description 11
- 239000000243 solution Substances 0.000 claims description 11
- 102000004169 proteins and genes Human genes 0.000 claims description 10
- BACYUWVYYTXETD-UHFFFAOYSA-N N-Lauroylsarcosine Chemical compound CCCCCCCCCCCC(=O)N(C)CC(O)=O BACYUWVYYTXETD-UHFFFAOYSA-N 0.000 claims description 8
- 238000001574 biopsy Methods 0.000 claims description 8
- 108090000623 proteins and genes Proteins 0.000 claims description 8
- 108700004121 sarkosyl Proteins 0.000 claims description 8
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical group OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 claims description 6
- 239000007983 Tris buffer Substances 0.000 claims description 6
- 239000011780 sodium chloride Substances 0.000 claims description 6
- 159000000000 sodium salts Chemical class 0.000 claims description 6
- LENZDBCJOHFCAS-UHFFFAOYSA-N tris Chemical group OCC(N)(CO)CO LENZDBCJOHFCAS-UHFFFAOYSA-N 0.000 claims description 6
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 6
- 244000052769 pathogen Species 0.000 claims description 5
- 239000006172 buffering agent Substances 0.000 claims description 4
- 239000002738 chelating agent Substances 0.000 claims description 4
- 238000003205 genotyping method Methods 0.000 claims description 4
- 238000009396 hybridization Methods 0.000 claims description 4
- 239000003550 marker Substances 0.000 claims description 4
- 239000003002 pH adjusting agent Substances 0.000 claims description 4
- 239000004094 surface-active agent Substances 0.000 claims description 4
- 238000011529 RT qPCR Methods 0.000 claims description 3
- 230000003321 amplification Effects 0.000 claims description 3
- 238000003199 nucleic acid amplification method Methods 0.000 claims description 3
- 238000004321 preservation Methods 0.000 claims description 3
- ZGTMUACCHSMWAC-UHFFFAOYSA-L EDTA disodium salt (anhydrous) Chemical compound [Na+].[Na+].OC(=O)CN(CC([O-])=O)CCN(CC(O)=O)CC([O-])=O ZGTMUACCHSMWAC-UHFFFAOYSA-L 0.000 claims description 2
- 238000002965 ELISA Methods 0.000 claims description 2
- 108010067770 Endopeptidase K Proteins 0.000 claims description 2
- 108091005461 Nucleic proteins Proteins 0.000 claims description 2
- 108091005804 Peptidases Proteins 0.000 claims description 2
- 102000035195 Peptidases Human genes 0.000 claims description 2
- 239000002535 acidifier Substances 0.000 claims description 2
- 229910001854 alkali hydroxide Inorganic materials 0.000 claims description 2
- 150000008044 alkali metal hydroxides Chemical group 0.000 claims description 2
- 230000003113 alkalizing effect Effects 0.000 claims description 2
- 238000004458 analytical method Methods 0.000 claims description 2
- 230000003139 buffering effect Effects 0.000 claims description 2
- 239000003795 chemical substances by application Substances 0.000 claims description 2
- 239000003814 drug Substances 0.000 claims description 2
- 229940079593 drug Drugs 0.000 claims description 2
- 239000005556 hormone Substances 0.000 claims description 2
- 229940088597 hormone Drugs 0.000 claims description 2
- 230000002934 lysing effect Effects 0.000 claims description 2
- 239000002207 metabolite Substances 0.000 claims description 2
- 235000019833 protease Nutrition 0.000 claims description 2
- 150000003839 salts Chemical class 0.000 claims description 2
- 238000012163 sequencing technique Methods 0.000 claims description 2
- 239000000523 sample Substances 0.000 description 16
- 238000000034 method Methods 0.000 description 2
- 108020004711 Nucleic Acid Probes Proteins 0.000 description 1
- 239000011324 bead Substances 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 238000000684 flow cytometry Methods 0.000 description 1
- 238000003364 immunohistochemistry Methods 0.000 description 1
- 238000002493 microarray Methods 0.000 description 1
- 239000002853 nucleic acid probe Substances 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP16162349.1A EP3222719B8 (en) | 2016-03-24 | 2016-03-24 | Use of an aqueous composition for dissolving biomolecules from a tissue sample |
| EP16162349.1 | 2016-03-24 | ||
| PCT/EP2017/056782 WO2017162721A1 (en) | 2016-03-24 | 2017-03-22 | Use of an aqueous composition for dissolving biomolecules from a tissue sample |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2019512274A JP2019512274A (ja) | 2019-05-16 |
| JP2019512274A5 true JP2019512274A5 (cg-RX-API-DMAC7.html) | 2020-04-23 |
Family
ID=55646357
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019501754A Withdrawn JP2019512274A (ja) | 2016-03-24 | 2017-03-22 | 組織試料由来の生体分子を溶解させるための水性組成物の使用 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20190100746A1 (cg-RX-API-DMAC7.html) |
| EP (2) | EP3222719B8 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2019512274A (cg-RX-API-DMAC7.html) |
| CN (1) | CN109153991B (cg-RX-API-DMAC7.html) |
| AR (1) | AR108041A1 (cg-RX-API-DMAC7.html) |
| AU (1) | AU2017237464B2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA3017679A1 (cg-RX-API-DMAC7.html) |
| DK (1) | DK3222719T3 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2802453T3 (cg-RX-API-DMAC7.html) |
| PL (2) | PL3222719T3 (cg-RX-API-DMAC7.html) |
| RU (1) | RU2745529C2 (cg-RX-API-DMAC7.html) |
| UY (1) | UY37165A (cg-RX-API-DMAC7.html) |
| WO (1) | WO2017162721A1 (cg-RX-API-DMAC7.html) |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3700555A (en) * | 1970-10-12 | 1972-10-24 | Technicon Instr | Method and apparatus for lymphocyte separation from blood |
| WO1996013214A1 (en) * | 1994-10-31 | 1996-05-09 | Boston Scientific Corporation | Biopsy needle |
| DE19758619C2 (de) | 1997-09-11 | 2003-12-18 | Biopsytec Gmbh | Vorrichtung zur Probenahme und Kennzeichnung eines Lebewesens |
| EP1088212B1 (de) * | 1998-05-25 | 2001-11-21 | Agrobiogen GmbH | Vorrichtung und verfahren zur gewinnung und erst-aufbereitung von gewebeproben für die molekulargenetische diagnostik |
| WO2002033128A2 (en) * | 2000-10-18 | 2002-04-25 | Pharmasset Limited | Multiplex quantification of nucleic acids in diseased cells |
| US7473532B2 (en) * | 2003-03-10 | 2009-01-06 | Expression Pathology, Inc. | Liquid tissue preparation from histopathologically processed biological samples, tissues and cells |
| BRPI0507186A (pt) * | 2004-01-30 | 2007-06-26 | Texas A & M Univ Sys | composição, métodos e usos para uma nova famìlia de peptìdeos |
| FR2917574B1 (fr) * | 2007-06-22 | 2010-05-07 | Chevillot Sarl | Boucle auriculaire de marquage avec dispositif de prelevement de tissus |
| WO2009085355A2 (en) * | 2007-10-01 | 2009-07-09 | Longhorn Vaccines & Diagnostics Llc | Biological specimen collection and transport system and methods of use |
| CA2707841C (en) * | 2007-12-04 | 2017-10-24 | Prionics Ag | Kit and method for detecting bovine viral diarrhea virus in tissue samples |
| CN104232617A (zh) * | 2008-05-23 | 2014-12-24 | 生命科技公司 | 用于dna提取的方法和试剂盒 |
| US10190152B2 (en) * | 2009-09-03 | 2019-01-29 | Becton, Dickinson And Company | Methods and compositions for direct chemical lysis |
| RU2422532C2 (ru) * | 2009-09-18 | 2011-06-27 | Общество с ограниченной ответственностью "РусИнкор-Мед" | Способ выделения низкомолекулярных ядерных рибонуклеопротеидов (рнп) из тканей и органов млекопитающих |
| WO2011091438A1 (en) * | 2010-01-25 | 2011-07-28 | George Mason Intellectual Properties, Inc. | Improved one-step cell and tissue preservative for morphologic and molecular analysis |
| US8652821B2 (en) * | 2010-10-20 | 2014-02-18 | Bio-Rad Laboratories, Inc. | Stabilized protease-containing solutions for purifying RNA-free DNA |
| CN107400711A (zh) * | 2011-08-03 | 2017-11-28 | 伯乐实验室公司 | 使用透化处理的细胞过滤小核酸 |
| ES2791760T3 (es) * | 2011-09-07 | 2020-11-05 | Sinai School Medicine | Ceramidasa y diferenciación celular |
| EP3594361A1 (en) * | 2012-03-28 | 2020-01-15 | Longhorn Vaccines and Diagnostics, LLC | Compositions and methods for the collection and isolation of nucleic acids from biological specimens suspected of containing mycobacterium tuberculosis |
| EP2900234B1 (en) * | 2012-09-28 | 2020-10-28 | Bose Institute | Cancer chemotherapeutic agent/formulation, manufacture and use thereof |
| WO2016029020A1 (en) * | 2014-08-20 | 2016-02-25 | Abogen, Inc. | Devices, solutions and methods for sample collection related applications |
-
2016
- 2016-03-24 PL PL16162349T patent/PL3222719T3/pl unknown
- 2016-03-24 EP EP16162349.1A patent/EP3222719B8/en active Active
- 2016-03-24 ES ES16162349T patent/ES2802453T3/es active Active
- 2016-03-24 DK DK16162349.1T patent/DK3222719T3/da active
-
2017
- 2017-03-22 RU RU2018133641A patent/RU2745529C2/ru active
- 2017-03-22 PL PL17711678T patent/PL3417060T3/pl unknown
- 2017-03-22 AU AU2017237464A patent/AU2017237464B2/en active Active
- 2017-03-22 WO PCT/EP2017/056782 patent/WO2017162721A1/en not_active Ceased
- 2017-03-22 US US16/086,908 patent/US20190100746A1/en not_active Abandoned
- 2017-03-22 EP EP17711678.7A patent/EP3417060B8/en active Active
- 2017-03-22 JP JP2019501754A patent/JP2019512274A/ja not_active Withdrawn
- 2017-03-22 UY UY0001037165A patent/UY37165A/es not_active Application Discontinuation
- 2017-03-22 AR ARP170100709A patent/AR108041A1/es unknown
- 2017-03-22 CA CA3017679A patent/CA3017679A1/en not_active Abandoned
- 2017-03-22 CN CN201780031557.3A patent/CN109153991B/zh active Active
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