JP2019500902A5 - - Google Patents
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- Publication number
- JP2019500902A5 JP2019500902A5 JP2018553039A JP2018553039A JP2019500902A5 JP 2019500902 A5 JP2019500902 A5 JP 2019500902A5 JP 2018553039 A JP2018553039 A JP 2018553039A JP 2018553039 A JP2018553039 A JP 2018553039A JP 2019500902 A5 JP2019500902 A5 JP 2019500902A5
- Authority
- JP
- Japan
- Prior art keywords
- morpholino oligomer
- antisense morpholino
- formula
- cpp
- antisense
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562387178P | 2015-12-23 | 2015-12-23 | |
| US62/387,178 | 2015-12-23 | ||
| PCT/US2016/068376 WO2017112888A1 (en) | 2015-12-23 | 2016-12-22 | Antisense antibacterial compounds and methods |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2019500902A JP2019500902A (ja) | 2019-01-17 |
| JP2019500902A5 true JP2019500902A5 (enExample) | 2020-02-06 |
| JP7393121B2 JP7393121B2 (ja) | 2023-12-06 |
Family
ID=59091240
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018553039A Active JP7393121B2 (ja) | 2015-12-23 | 2016-12-22 | アンチセンス抗菌化合物および方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US11142764B2 (enExample) |
| EP (1) | EP3394262B1 (enExample) |
| JP (1) | JP7393121B2 (enExample) |
| AU (1) | AU2016379402B2 (enExample) |
| CA (1) | CA3009342A1 (enExample) |
| WO (1) | WO2017112888A1 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2015175977A2 (en) | 2014-05-16 | 2015-11-19 | Geller Bruce L | Antisense antibacterial compounds and methods |
| EP3569252B1 (en) | 2014-05-19 | 2021-12-15 | Oregon State University | Antisense antibacterial compounds and methods |
| AU2015372560B2 (en) | 2014-12-31 | 2021-12-02 | Board Of Regents, The University Of Texas System | Antisense antibacterial compounds and methods |
| AU2016379399B2 (en) | 2015-12-23 | 2022-12-08 | Board Of Regents, The University Of Texas System | Antisense antibacterial compounds and methods |
| GB2579253A (en) | 2018-11-28 | 2020-06-17 | Pedanius Therapeutics Ltd | Antibacterial antisense agents |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5185444A (en) | 1985-03-15 | 1993-02-09 | Anti-Gene Deveopment Group | Uncharged morpolino-based polymers having phosphorous containing chiral intersubunit linkages |
| US5521063A (en) | 1985-03-15 | 1996-05-28 | Antivirals Inc. | Polynucleotide reagent containing chiral subunits and methods of use |
| US5166315A (en) | 1989-12-20 | 1992-11-24 | Anti-Gene Development Group | Sequence-specific binding polymers for duplex nucleic acids |
| US5217866A (en) | 1985-03-15 | 1993-06-08 | Anti-Gene Development Group | Polynucleotide assay reagent and method |
| US5034506A (en) | 1985-03-15 | 1991-07-23 | Anti-Gene Development Group | Uncharged morpholino-based polymers having achiral intersubunit linkages |
| AU5661386A (en) | 1985-03-15 | 1986-10-13 | Stirchak, E. | Stereoregular polynucleotide-binding polymers |
| US5506337A (en) | 1985-03-15 | 1996-04-09 | Antivirals Inc. | Morpholino-subunit combinatorial library and method |
| WO1993001286A2 (en) | 1991-06-28 | 1993-01-21 | Massachusetts Institute Of Technology | Localized oligonucleotide therapy |
| DK2111876T3 (da) | 1995-12-18 | 2011-12-12 | Angiodevice Internat Gmbh | Tværbundne polymerpræparater og fremgangsmåder til anvendelse deraf |
| US6245747B1 (en) | 1996-03-12 | 2001-06-12 | The Board Of Regents Of The University Of Nebraska | Targeted site specific antisense oligodeoxynucleotide delivery method |
| US6677153B2 (en) | 1999-11-29 | 2004-01-13 | Avi Biopharma, Inc. | Antisense antibacterial method and composition |
| US6965025B2 (en) | 2001-12-10 | 2005-11-15 | Isis Pharmaceuticals, Inc. | Antisense modulation of connective tissue growth factor expression |
| ES2351976T3 (es) | 2003-04-29 | 2011-02-14 | Avi Biopharma, Inc. | Composiciones para mejorar el transporte y la eficacia antisentido de análogos de ácidos nucleicos en células. |
| US8067571B2 (en) * | 2005-07-13 | 2011-11-29 | Avi Biopharma, Inc. | Antibacterial antisense oligonucleotide and method |
| EP1915161B1 (en) | 2005-07-13 | 2017-04-26 | Sarepta Therapeutics, Inc. | Antisense antibacterial method and compound |
| AU2008271050B2 (en) * | 2007-06-29 | 2014-11-06 | Sarepta Therapeutics, Inc. | Tissue specific peptide conjugates and methods |
| US20100016215A1 (en) | 2007-06-29 | 2010-01-21 | Avi Biopharma, Inc. | Compound and method for treating myotonic dystrophy |
| US8299206B2 (en) | 2007-11-15 | 2012-10-30 | Avi Biopharma, Inc. | Method of synthesis of morpholino oligomers |
| CA2884340C (en) | 2007-11-15 | 2017-07-25 | Sarepta Therapeutics, Inc. | Method of synthesis of morpholino oligomers |
| US8076476B2 (en) | 2007-11-15 | 2011-12-13 | Avi Biopharma, Inc. | Synthesis of morpholino oligomers using doubly protected guanine morpholino subunits |
| US20110269665A1 (en) | 2009-06-26 | 2011-11-03 | Avi Biopharma, Inc. | Compound and method for treating myotonic dystrophy |
| WO2012031243A2 (en) * | 2010-09-03 | 2012-03-08 | Avi Biopharma, Inc. | dsRNA MOLECULES COMPRISING OLIGONUCLEOTIDE ANALOGS HAVING MODIFIED INTERSUBUNIT LINKAGES AND/OR TERMINAL GROUPS |
| PL2623507T3 (pl) | 2010-09-30 | 2017-03-31 | Nippon Shinyaku Co., Ltd. | Pochodna kwasu morfolinonukleinowego |
| WO2012150960A1 (en) | 2011-05-05 | 2012-11-08 | Avi Biopharma, Inc. | Peptide oligonucleotide conjugates |
| WO2015175977A2 (en) * | 2014-05-16 | 2015-11-19 | Geller Bruce L | Antisense antibacterial compounds and methods |
| EP3569252B1 (en) * | 2014-05-19 | 2021-12-15 | Oregon State University | Antisense antibacterial compounds and methods |
| AU2015372560B2 (en) | 2014-12-31 | 2021-12-02 | Board Of Regents, The University Of Texas System | Antisense antibacterial compounds and methods |
| AU2016379399B2 (en) | 2015-12-23 | 2022-12-08 | Board Of Regents, The University Of Texas System | Antisense antibacterial compounds and methods |
| US20200283768A1 (en) | 2017-10-23 | 2020-09-10 | Board Of Regents, The University Of Texas System | Antisense antibacterial compounds and methods |
-
2016
- 2016-12-22 AU AU2016379402A patent/AU2016379402B2/en active Active
- 2016-12-22 US US16/064,306 patent/US11142764B2/en active Active
- 2016-12-22 WO PCT/US2016/068376 patent/WO2017112888A1/en not_active Ceased
- 2016-12-22 EP EP16880107.4A patent/EP3394262B1/en active Active
- 2016-12-22 JP JP2018553039A patent/JP7393121B2/ja active Active
- 2016-12-22 CA CA3009342A patent/CA3009342A1/en active Pending
-
2021
- 2021-10-12 US US17/498,880 patent/US12209240B2/en active Active
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