JP2019218297A - Dental separation material - Google Patents

Abstract

To provide a dental separation material for easily removing a dental adhesion adhered to a non-adhesion scheduled plane, capable of easily removing a separation material itself, and preventing adhesion error to an adhesion scheduled plane, and even if adhesion occurs, capable of being aware of and dealt with it.SOLUTION: There is provided a dental separation material in which, a water soluble composition comprising: (A) 100 mass parts of a water soluble organic solvent whose boiling point is 150°C or greater, such as propylene glycol; (B) 0.1 mass parts or more and 50 mass parts or less of a water soluble polymer such as hydroxypropyl cellulose; and (C) 0.001 mass parts or more and 5 mass parts or less of water soluble dye such as brilliant blue FCF, is applied in advance, to a non-adhesion scheduled plane of a repaired tooth or a dental prosthetic.SELECTED DRAWING: None

Description

  The present invention relates to compositions used in dentistry. More specifically, the present invention relates to a dental separating material used for preventing excess dental adhesive from adhering to a non-joining surface.

  BACKGROUND ART In repairing a lost tooth part due to caries or the like, a filling restoration material called a composite resin and a prosthesis such as a ceramic or metal crown restoration are widely used. At the time of such restoration, a dental adhesive containing a polymerizable monomer and inorganic particles is always used in combination. The performance of such dental adhesives has been significantly improved in recent years, and many exhibit very high adhesive strength and high mechanical strength. On the other hand, such a dental adhesive is erroneously formed at an unintended location, for example, when excess dental adhesive protrudes from between objects to be bonded at the time of bonding, or when applying (applying) the dental adhesive. For example, it may unintentionally adhere to a surface different from the surface to be bonded (hereinafter, also referred to as a “non-bonding scheduled surface”). Dental adhesive adhered to the surface of a tooth or a prosthesis becomes a home of bacteria in the oral cavity and may cause periodontal disease. Therefore, it is necessary to completely remove the non-adhesive part of the dental adhesive.

  A method used as a method for removing a dental adhesive that has adhered to a non-bonding surface is physical removal using a scaler, dental floss, or the like. However, it has not been possible to completely remove it by such a method. Because, it is difficult to find all the small deposits in the narrow oral cavity, and even if it can be found, it is not easy to remove because of the high adhesive strength and high mechanical strength of the adhesive itself as described above That's why. In addition, there is a risk that the peripheral portion may be damaged if physically difficult to remove.

  On the other hand, at the time of dental treatment, there is known a separating material for responding to a demand for preventing adhesion between a cavity surface of a tooth formed with a cavity and a resin or a temporary sealing material used for restoration. It is also known that by applying a material to a non-bonding surface in advance, it is possible to easily remove the dental adhesive adhering to the non-bonding surface (see Patent Documents 1 and 2).

  That is, in Patent Document 1, after a cavity is formed in a carious tooth, a separating material is applied to the cavity surface, and then a curable resin is filled and cured, a cured resin body is taken out from the cavity, and the cavity surface is pre-treated. A method of restoring a cavity of a carious tooth by bonding a cured resin body cured with an adhesive to a cavity, wherein a separating material applied to the cavity surface before filling with an uncured curable resin is (A A) a hydroxyl-containing compound selected from glycerin or polyethylene glycol, which has at least two hydroxyl groups in the molecule, has a freezing point of 15 ° C. or lower, and is water-soluble or water-dispersible, and 15 to 95 parts by weight; A hydroxyl group-containing compound 5-85 selected from water-soluble or water-dispersible polyethylene glycol having at least two hydroxyl groups in the molecule, having a freezing point of 30 ° C. or higher, and The amount unit (here, the sum is 100 parts by weight of (A) and (B)) is a discloses a dental separation material containing, the separation material can also be used for the purpose.

  Patent Document 2 discloses a resin separating material that enables a resin-based temporary sealing material to be easily separated from the resin, and the separating material itself forms a continuous solid film on a tooth surface, that is, a so-called solid film forming ability. As a separating material, (A) a water-soluble polymer which is solid at 30 ° C., is insoluble or hardly soluble in alkyl methacrylate and is soluble in 5 parts by weight or more in 100 parts by weight of water, and (B) methyl alcohol , Ethyl alcohol, 1-propyl alcohol, 2-propyl alcohol, 1-butyl alcohol, 2-butyl alcohol, acetone and methyl ethyl ketone. A mixed aqueous solvent with water, wherein the mixed aqueous medium contains a water-soluble organic solvent in an amount of 50% by weight or more. Dental resin separation material comprising a composition unit containing a medium is disclosed, the separation material is that it can be used for the purpose.

Patent No. 4232214 Japanese Patent No. 4712164 JP 2000-128723 A JP 2004-284969 A

  Since the separation material disclosed in Patent Literature 1 uses a component having a low freezing point, it was necessary to heat the mixture to, for example, 70 ° C. and mix to form a paste. Further, the obtained paste was white or translucent white, had poor visibility, and could not be confirmed even when the separating material was unintentionally adhered to the portion to be adhered. If the separating material adheres to the surface of the part to be bonded (hereinafter, also simply referred to as “surface to be bonded”) to which the adhesive is applied to perform bonding, the bonded prosthesis or filler may fall off. Could develop into a major problem.

  Further, the separation material disclosed in Patent Document 2 is premised on forming a solid film, and for that purpose, air blowing is performed in the oral cavity using a water-soluble organic solvent having a relatively low boiling point such as methyl alcohol. For example, it is necessary to volatilize the water-soluble organic solvent. However, when air blowing is performed, not only the separation material may be scattered in the oral cavity, but also the separation material once formed into a solid film has a low solubility in water, which makes it difficult to remove itself. there were. Further, Patent Document 2 does not particularly recognize a problem caused by the poor visibility.

  Therefore, the present invention is a separating material that can easily remove the dental adhesive that has adhered to the non-bonding surface, and the separating material itself can be easily removed, and furthermore, the separating material can be erroneously attached to the bonding surface. It is an object of the present invention to provide a dental separating material that can prevent such a situation and even if it adheres, can notice the situation and take appropriate measures.

  The present inventor, after coating on the surface to be not adhered, stays in the place where it was applied in a state of a highly viscous liquid or semi-solid without requiring a special drying operation, and was adhered thereon by washing with water. It can be easily removed from the non-adhesive surface together with the dental adhesive, and the addition of a water-soluble dye enhances visibility, making it easier to apply so that it does not adhere to the adhesive surface during application. In the case of adhesion, the authors conducted a study based on the development concept of making it easy to notice the problem and removing it, or to apply it again after cleaning. As a result, they succeeded in finding a separation material that can solve the above-mentioned problems, and have completed the present invention.

That is, the present invention, when bonding a dental prosthesis or a dental filler to a tooth to be repaired using a dental adhesive, the surface of the non-adhered portion of the tooth to be repaired, the dental prosthesis or the dental prosthesis. By applying in advance to the surface of the non-adhesive portion of the dental filler and the non-adhesive surface consisting of at least one selected from the group consisting of the surfaces of the teeth surrounding the tooth to be repaired, A dental separating material for preventing the adhesive for directly adhering to the non-adhesion expected surface,
(A) a water-soluble organic solvent having a boiling point of 150 ° C. or more: 100 parts by mass,
(B) water-soluble polymer: 0.1 to 50 parts by mass, and (C) water-soluble dye: a water-soluble composition containing 0.001 to 5 parts by mass. The dental separating material described above.

  The separation material of the present invention is preferably made of a water-soluble liquid composition having a complex viscosity at 25 ° C of 400 mPa · s or more and 120,000 mPa · s or less.

  It is preferable that the composition further comprises 0.001 to 1 part by mass of a polymerization inhibitor based on 100 parts by mass of the water-soluble organic solvent (A).

  Patent Literature 3 and Patent Literature 4 disclose a surface coating material and an oxygen barrier material containing a water-soluble organic solvent and a water-soluble polymer. However, these documents only describe that the above-mentioned surface coating material or oxygen barrier material is used to reduce polymerization inhibition due to oxygen in the air. It is neither disclosed nor suggested for use in wood.

  The dental separation material of the present invention has improved visibility due to the addition of a water-soluble dye, so it is easy to apply it to the non-bonding surface so as not to adhere to the bonding surface, and if it is mistakenly attached to the bonding surface. Has the characteristic that it can be easily noticed and removed, or it can be washed and then applied again. In addition, after application to the non-bonding surface, it remains at the place where it was applied in a viscous liquid or semi-solid state without requiring any special drying operation. Not only can it be easily removed, etc., but also can be easily removed from the non-bonding surface by washing with water (in some cases, together with the dental adhesive adhered thereon). Also have.

  Therefore, by using the dental separating material of the present invention, while avoiding the danger of poor bonding that leads to a major problem such as the prosthesis and the filler falling off, the surface itself does not remain, and the non-bonded surface It is possible to easily remove the dental adhesive that has adhered to the surface.

  The separating material of the present invention, when bonding a dental prosthesis or a dental filler to a tooth to be repaired using a dental adhesive, the surface of the non-adhered portion of the tooth to be repaired, the dental prosthesis or The surface of the non-adhesive portion of the dental filler, and the non-adhesive surface consisting of at least one selected from the group consisting of the surface of the surrounding teeth of the tooth to be repaired, is applied in advance to the non-adhesive surface during the adhering operation. A dental separating material for preventing a dental adhesive from directly adhering to the non-bonding surface, wherein (A) a water-soluble organic solvent having a boiling point of 150 ° C. or more: 100 parts by mass, and (B) a water-soluble organic solvent. It is characterized by comprising a water-soluble composition containing a polymer: 0.1 to 50 parts by mass, and (C) a water-soluble dye: 0.001 to 5 parts by mass.

  To prevent the dental adhesive from directly adhering to the non-bonding surface during the bonding operation means to prevent the dental adhesive from directly contacting the non-bonding surface. However, it is permissible that the dental adhesive is indirectly adhered to the non-bonding surface via the dental separating material of the present invention. In this case, the dental adhesive which has indirectly adhered can be easily removed together with the dental separating material of the present invention by an operation such as washing with water, so that it does not remain in the oral cavity. In the present invention, the term "water-soluble" means a property of dissolving at a concentration of 0.5 parts by weight or more in 100 parts by weight of water at 25 ° C.

  Hereinafter, (A) a water-soluble organic solvent, (B) a water-soluble polymer, and (C) a water-soluble dye used in the separation material of the present invention, and other components that can be further added as necessary, are described below. Details will be described.

<(A) Water-soluble organic solvent having a boiling point of 150 ° C. or higher>
The water-soluble organic solvent is not particularly limited as long as it is a water-soluble organic solvent having a boiling point of 150 ° C. or higher, and a known water-soluble organic solvent can be used.

  Preferred examples of the water-soluble organic solvent include n-octanol, ethylene glycol, 1,4-dioxane, dimethylformamide, hexamethylphosphoric triamide, dimethyl sulfoxide, polyethylene glycol, and propylene glycol. One of these water-soluble organic solvents may be used alone, or two or more thereof may be used in combination. When two or more water-soluble organic solvents are used, the reference mass is the total mass of the water-soluble organic solvents.

  From the viewpoint that the risk of volatilization in the oral cavity and the inhalation of the water-soluble organic solvent by the user and the risk of forming a solid film that is difficult to remove is lower, an aqueous solution having a boiling point of 160 ° C or higher, particularly 180 ° C or higher. It is preferable to use a neutral organic solvent. It is preferable to use an alcohol compound from the viewpoint of biosafety. Specific examples of the water-soluble organic solvent particularly preferably used from such a viewpoint include ethylene glycol and propylene glycol.

<(B) Water-soluble polymer>
The water-soluble polymer is not particularly limited as long as it is a polymer compound having water solubility, and gelatin, collagen, polyvinyl alcohol, polyvinylpyrrolidone, carboxyvinyl polymer, alginate, propylene glycol alginate, methylcellulose, ethylcellulose, hydroxymethylcellulose, Hydroxyethyl cellulose, hydroxypropyl cellulose and the like can be used. Among them, it is preferable to use a cellulose derivative because it is chemically stable.

  In addition, (B) the water-soluble polymer is contained in the (A) water-soluble organic solvent at room temperature because it is not necessary to perform heating which may cause denaturation of the component when preparing the dental separation material. It is preferable that the composition is uniformly dispersed to form a uniform liquid composition. (C) The combination of a water-soluble dye and (A) aqueous It is particularly preferred that the compound is uniformly dissolved in a neutral organic solvent to form a colorless and transparent liquid composition. From such a viewpoint, it is most preferable to use hydroxypropyl cellulose as the water-soluble polymer.

  In the present invention, the compounding amount of (B) the water-soluble polymer is 0.1 mass per 100 parts by mass of the (A) water-soluble organic solvent so that high coatability and separability can be exhibited. Parts by mass and not more than 50 parts by mass. In order to exhibit higher coatability and separability, (A) it is preferably from 1 to 30 parts by mass, and more preferably from 2 to 10 parts by mass, per 100 parts by mass of the water-soluble organic solvent. Is particularly preferred. In addition, only one type of water-soluble polymer may be used, or two or more types may be used in combination. When two or more water-soluble polymers are used, the reference mass is the total mass of the water-soluble polymers.

<(C) Water-soluble dye>
The water-soluble dye is not particularly limited as long as it has water solubility and can be dissolved in the component (A) and / or the component (B). Amaranth, erythrosine, alla red AC, pneucoxin, phloxine , Rose Bengal, Acid Red, Tartrazine, Sunset Yellow FCF, Fast Green FCF, Brilliant Blue FCF, Tar Dyes such as Indigo Carmine, Caramel Dye, Gardenia Yellow Dye, Gardenia Red Dye, Gardenia Blue Dye, Anatoine Dye, Anthocyanin Dye , Paprika color, safflower color, red koji color, flavonoid color, cochineal color, red cabbage color and the like can be used without particular limitation. Among these, a blue dye is preferably used from the viewpoint of visibility in the oral cavity, and brilliant blue FCF is particularly preferably used.

  The amount of the water-soluble dye (C) is 0.001 to 5 parts by mass per 100 parts by mass of the water-soluble organic solvent (A) from the viewpoint of visibility. The amount of the water-soluble dye (C) is preferably 0.01 to 3 parts by mass per 100 parts by mass of the (A) water-soluble organic solvent, because the higher visibility is efficiently obtained. , 0.04 parts by mass or more and 1 part by mass or less is particularly preferable. In addition, only one type of water-soluble dye may be used, or two or more types may be used in combination. When two or more water-soluble dyes are used, the reference mass is the total mass of the water-soluble dyes.

<Other additives>
In the dental separating material of the present invention, when the dental adhesive and the dental separating material come into contact with each other, the curing of the dental adhesive is inhibited, and a polymerization inhibitor is used for the reason that the dental adhesive is easily separated. It is preferable to mix them. Suitable polymerization inhibitors include di-t-butylhydroxy-p-cresol, hydroquinone monomethyl ether and the like. When such a polymerization inhibitor is compounded, the compounding amount is preferably in the range of 0.0001 to 5 parts by mass, more preferably 0.001 part by mass, per 100 parts by mass of the water-soluble organic solvent (A). It is particularly preferable to mix in the range of not less than 2 parts by mass and most preferably in the range of not less than 0.01 part by mass and not more than 1 part by mass.

  In the dental separation material of the present invention, water, a fragrance, an antibacterial agent and the like can be blended as long as the effect is not impaired.

  Incidentally, the dental separating material of the present invention is an additive that promotes the curing of the dental adhesive, that is, an organic peroxide, an oxidizing agent such as an inorganic peroxide, an amine compound, a thiourea compound, a sulfinic acid compound, It preferably does not contain a reducing agent such as a barbituric acid compound, a borate compound or a borane compound, or a transition metal compound such as a vanadium compound or a copper compound.

<Viscosity>
The viscosity of the dental separating material of the present invention is not particularly limited. However, if the viscosity is too low, it is difficult to stay on the coated surface, and if the viscosity is too high, it is difficult to apply. From such a viewpoint, the dental separation material of the present invention preferably has a complex viscosity at 25 ° C of 400 mPa · s or more and 120,000 mPa · s or less, and more preferably 6000 mPa · s to 90000 mPa · s or less. It is particularly preferably from 10,000 mPa · s to 40,000 mPa · s.

  The dental separation material of the present invention can be easily prepared by mixing a predetermined amount of each component at room temperature. The prepared dental separation material is filled in a container such as a syringe or a bottle, and is taken out of a necessary amount from these at the time of use, and is applied to a surface to be not bonded to be used. When applying, it may be applied directly from a syringe, or may be applied using a sponge piece or a small brush.

  Hereinafter, the present invention will be described with reference to Examples, but the present invention is not limited thereto. Hereinafter, abbreviations of the substances used in each of the examples and comparative examples will be described.

<(A) Water-soluble organic solvent>
PG; propylene glycol (boiling point: 188 ° C)
EG; ethylene glycol (boiling point: 197 ° C)
OC; n-octanol (boiling point: 195 ° C)
<(B) Water-soluble polymer>
HPC; hydroxypropylcellulose CMC; carboxymethylcellulose <(C) water-soluble dye>
BR; Brilliant Blue FCF
AM; Amaranth.

Example 1
<Preparation of dental separation material>
0.04 parts by mass of brilliant blue FCF was added to 100 parts by mass of propylene glycol, and the mixture was stirred at room temperature to confirm complete dissolution. Thereafter, 5 parts by mass of hydroxypropylcellulose was further added, and the mixture was stirred at room temperature to confirm that the mixture was uniform.

<Evaluation of separation ability>
The bovine teeth are polished equilibrium on the lips with No. 800 emery paper to form a flat enamel surface, and the surface is coated with the dental separating material of the above composition 1, and then a dental adhesive is further applied thereon. (Relix Unicem 2 Automix, manufactured by 3MS Co., Ltd.) was applied. Then, after leaving in a 37 ° C. constant temperature bath for 3 hours, the dental adhesive was removed with a dental probe, and the separating ability was evaluated based on the following evaluation criteria.
Evaluation criteria:
3: Complete removal within 1 second 2: Complete removal within 2 to 3 seconds 1: Complete removal takes 4 seconds or more Similarly, the above evaluation is performed 10 times in total, and the average value is used for the dental treatment. When the separation power of the separation material was used, the separation power was 3.

<Measurement of complex viscosity>
Using a rheometer MCR302 manufactured by Anton Paar, a dental separation material of the composition 1 was sandwiched between parallel disks having a radius of 25 mm, a measurement temperature of 25 ° C., a gap of 0.5 mm, a strain γ = 0.1%, and a frequency f. When the complex viscosity was measured under the condition of = 1 Hz, the complex viscosity was 9.0 × 10 ⁴ mPa · s.

<Evaluation of visibility>
The dental separation material of the composition 1 was applied to a white portion of an opacity test paper (manufactured by TR Giken Co., Ltd.) in a size of 1 mm or less in diameter. Thereafter, the visibility was evaluated based on the following evaluation criteria.
Evaluation criteria:
3: Visible within 1 second 2: Visible within 2 to 3 seconds 1: Visible for 4 seconds or more Similarly, the above evaluation was performed 10 times in total, and the average value was regarded as the visibility of the dental separation material. However, the visibility was 3.

Examples 2 to 12 and Comparative Examples 1 and 2
The same operation as in Example 1 was performed, except that the compounding amounts of the respective components were changed to the compounding amounts shown in Table 1, and the same evaluation was performed. Table 2 shows the results and the composition used.

Example 13
Composition 1 of the dental separation material was prepared in the same manner as in Example 1, and the obtained dental separation material was evaluated for removability as follows. That is, 0.05 g of the prepared dental separation material was applied on a slide glass, and air blowing was performed for 30 seconds using a dental unit (Utilio, manufactured by Morita). Further, water was sprayed for 10 seconds using the same dental unit, and then air blowing was performed for 10 seconds. The amount of the remaining dental separation material on the slide glass was evaluated. The air blow for 30 seconds before spraying water is an operation that is not particularly necessary in actual application, but was performed to confirm the removability under severe conditions such as evaporation of the solvent.
The evaluation criteria for the removability were as shown below. The same evaluation was performed 10 times in total, and the average value was regarded as the removability of the dental separation material. Table 3 shows the results.
Evaluation criteria:
3: 0-10% residual rate of dental separation material
2: Residual rate of dental separation material 11 to 80%
1: The residual ratio of the dental separating material is 81 to 100%.

Example 14 and Comparative Examples 3 and 4
A dental separation material was prepared in the same manner as in Example 1, except that the amounts of the components were changed to the amounts shown in Table 1. The same evaluation as in Example 13 was performed on the obtained dental separation material. Table 3 shows the results and the composition used.

  Examples 1 to 12 contained (A) a water-soluble organic solvent, (B) a water-soluble polymer, and (C) a water-soluble dye, and exhibited good separation ability, complex viscosity, and visibility. Comparative Example 1 was poor in visibility because it did not contain (C) a water-soluble dye. Comparative Example 2 had no (B) water-soluble polymer, and thus had poor separation ability.

  In Examples 13 and 14, since the water-soluble organic solvent had a boiling point of 150 ° C. or higher, the removability was excellent even after air blowing was performed. On the other hand, in Comparative Examples 3 and 4, since a solid film was formed after air blowing, the removability was very poor.

Claims (4)

When bonding a dental prosthesis or a dental filler to a tooth to be repaired using a dental adhesive, the surface of the non-adhered portion of the tooth to be repaired, the non-adhesion of the dental prosthesis or the dental filler, The dental adhesive is applied to the non-adhesive surface of at least one selected from the group consisting of the surface of the adhesive portion and the peripheral teeth of the tooth to be repaired by applying the dental adhesive during the bonding operation. A dental separating material for preventing direct adhesion to a surface to be bonded,
(A) a water-soluble organic solvent having a boiling point of 150 ° C. or more: 100 parts by mass,
(B) water-soluble polymer: 0.1 to 50 parts by mass, and (C) water-soluble dye: a water-soluble composition containing 0.001 to 5 parts by mass. Said dental separating material.   The dental separation material according to claim 1, comprising a water-soluble liquid composition having a complex viscosity at 25 ° C of 400 mPa · s or more and 120,000 mPa · s or less.   The dental separation material according to claim 1 or 2, wherein the (B) water-soluble polymer is a cellulose derivative.   The dental separating material according to any one of claims 1 to 3, further comprising 0.001 to 1 part by mass of a polymerization inhibitor based on 100 parts by mass of the water-soluble organic solvent (A).