JP2019195805A - Hydrogen dissolved water manufacturing apparatus and method, and hydrogen supply apparatus - Google Patents

Abstract

To provide an apparatus and a method for stably manufacturing high-concentration hydrogen-dissolved water.SOLUTION: A hydrogen-dissolved water manufacturing apparatus has filtration means 10 for filtering raw water, means 40 for dissolving hydrogen in the filtered raw water, means 50 for removing excess hydrogen from raw water in which hydrogen is dissolved, and means for supplying hydrogen. A hydrogen-dissolved water manufacturing method has a step of filtering raw water to manufacture filtered water, a step of mixing hydrogen into the filtered water and dissolving the hydrogen by applying pressure, and a step of removing excess hydrogen from the filtered water in which hydrogen is dissolved.SELECTED DRAWING: Figure 2

Description

  The present invention relates to a method and an apparatus for producing hydrogen-dissolved water. More specifically, the present invention relates to a method and apparatus for producing hydrogen-dissolved water for dialysis fluid or dialysis stock solution.

  Attempts have been made to treat the disease by the action of hydrogen using hydrogen-dissolved water in which hydrogen is dissolved in the dialysate or dialysis stock solution. However, when electrolyzed hydrogen-dissolved water is used, the liquid becomes alkaline. (Patent Document 1).

On the other hand, when hydrogen is dissolved by pressure, it is difficult to dissolve a sufficient amount of hydrogen, and it is difficult to stabilize the hydrogen concentration.
Therefore, there has been a demand for a technique and a method for stably producing high-concentration hydrogen-dissolved water.
There has also been a demand for a method and apparatus for supplying hydrogen to patients who have difficulty in dialysis.

JP 2017-087110 A

  Produces stable high-concentration hydrogen-dissolved water.

According to this specification, the following invention is provided.
(1) filtration means for filtering raw water;
Means for dissolving hydrogen in the filtered raw water;
An apparatus for producing a hydrogen-dissolved water solution, comprising: means for removing excess hydrogen from raw water in which hydrogen is dissolved; and means for supplying hydrogen.
(2) The apparatus for producing a hydrogen-dissolved water solution according to (1), wherein the means for dissolving hydrogen is means for dissolving hydrogen until hydrogen is supersaturated.
(3) The apparatus for producing a hydrogen-dissolved water solution according to (1) or (2), wherein the means for dissolving hydrogen includes a circulation means.
(4) The hydrogen-dissolved water production apparatus according to any one of (1) to (3), wherein the means for removing excess hydrogen is a means for discharging hydrogen by reducing pressure.
(5) The hydrogen-dissolved water production apparatus according to any one of (1) to (4), wherein the hydrogen-dissolved water is a dialysis solution or a dialysis stock solution.
(6) a step of producing filtered water by filtering raw water;
Mixing hydrogen into filtered water and applying pressure to dissolve hydrogen;
Removing excess hydrogen from filtered water in which hydrogen is dissolved;
A method for producing hydrogen-dissolved water having:
(7) The method for producing hydrogen-dissolved water according to (6), wherein the step of dissolving hydrogen is a step of dissolving hydrogen until hydrogen becomes supersaturated.
(8) The method for producing hydrogen-dissolved water according to (6) or (7), wherein the means for dissolving hydrogen includes a circulation step.
(9) The method for producing hydrogen-dissolved water according to any one of (6) to (8), wherein the step of removing excess hydrogen is a step of releasing hydrogen by reducing pressure.
(10) The method for producing hydrogen-dissolved water according to any one of (6) to (9), wherein the hydrogen-dissolved water is a dialysate or a dialysis stock solution.
(11) A hydrogen gas supply device including a pure water tank, a hydrogen generation cell, a cooling mechanism, a hydrogen-water separation mechanism, and a pump.
(12) The hydrogen gas supply device according to (11), wherein hydrogen and water are separated by a special filter.
(13) A method of supplying hydrogen gas by the hydrogen gas supply device according to (11) or (12).

  According to the present invention, high-concentration hydrogen-dissolved water can be produced stably.

FIG. 1 is a schematic diagram of the principle of the present invention. FIG. 2 is a diagram according to one embodiment (continuous operation) of the present invention (Example 1). FIG. 3 is a diagram according to one embodiment (intermittent operation) of the present invention (Example 1). FIG. 4 is a graph showing that the redox potential is decreased by the apparatus of the present invention (Example 1). FIG. 5 is a graph showing the change with time of the oxidation-reduction potential when the liquid is exchanged in the apparatus of the present invention (Example 2). FIG. 6 is a graph showing the change over time of the oxidation-reduction potential of each device during hydrogenation of the device according to one embodiment of the present invention (Example 3). FIG. 7 is a graph showing the change over time of the oxidation-reduction potential when the apparatus of the present invention, bubbling, and nanoengine are used (Example 4). FIG. 8 shows the change over time of the oxidation-reduction potential of hydrogen-dissolved water prepared by the apparatus of the present invention (Example 5). FIG. 9 is a schematic view of the hydrogen supply apparatus of the present invention (Example 6). FIG. 10 is a photograph of a nasal cannula for supplying hydrogen from the patient's nose (Example 6).

In this specification, hydrogen-dissolved water refers to a liquid in which hydrogen gas is dissolved. The liquid may be pure water or a solution. Preferably, it is a solution (dialysate) that can be used for artificial dialysis, but is not limited thereto, and may be a drinking water or an infusion solution. In short, any liquid that dissolves hydrogen may be used.
The form of hydrogen gas dissolution may be either macro bubble or micro bubble, and may include both.

  According to one embodiment of the present invention, hydrogen can be dissolved in the dialysate or dialysis stock solution under pressure. In this case, the pressure to be applied is preferably 0.03 to 0.5 MPa (megapascal), more preferably 0.05 to 0.4 MPa, and still more preferably 0.07 to 0.4 MPa.

  The dialysate that can be used in the apparatus or method of the present invention is, for example, kinderial dialysate AF4 A solution (sodium chloride 1306.8 g, calcium chloride 31.32 g, calcium chloride hydrate 42.42 g, magnesium chloride 21.36 g, anhydrous sodium acetate 103.2 g, glucose 262.5 g, pH adjuster (glacial acetic acid 25.2 g dissolved in water to adjust to 6 L), solution B (sodium bicarbonate 485.1 g dissolved in water to 7.46 L), or carbo Star dialysate / L (A solution: sodium chloride 1289g, potassium chloride 31g, calcium chloride hydrate 46g, magnesium chloride 21g, glucose 315g, citric acid hydrate (appropriate amount as pH adjuster), sodium citrate hydrate (Appropriate amount) dissolved in water and adjusted to 6 L, Liquid B: 621 g of sodium bicarbonate dissolved in water and adjusted to 7.6 L) are preferably used, but are not limited thereto.

  In order to stably produce high-concentration hydrogen-dissolved water, it is preferable that hydrogen be dissolved in a liquid by applying a pressure and passing through a long tube to be in a supersaturated state. The long tube is preferably 50 to 200 cm, more preferably 80 to 120 cm, still more preferably 80 to 100 cm. A preferable tube thickness is 0.05 to 0.6 cm, and more preferably 0.1 to 0.3 cm. Under these conditions, the feed rate of the raw water is preferably about 20 ml / min, and the flow rate of hydrogen gas is preferably 3 to 6 ml / min. However, the flow rate of the feed or gas feed is the size of the apparatus, the thickness of the tube, etc. Can be determined by a method well known to those skilled in the art. The mixture of hydrogen gas and filtered raw water is preferably structured to circulate the tube under high pressure, and the hydrogen is dissolved in the filtered raw water by circulation to be supersaturated. The supersaturated state is a state containing hydrogen at a concentration higher than the saturated concentration at normal pressure (1 atm), and is a state in which hydrogen is separated when the pressure is returned to normal pressure (1 atm, 0.101325 MPa).

  If supersaturated hydrogen-dissolved water is used as it is, hydrogen bubbles may be generated in the body during dialysis. Therefore, in the present invention, means for separating and removing excess hydrogen from supersaturated hydrogen-dissolved water or Have a method.

  In the case of a personal device with a small throughput, surplus hydrogen can be separated by at least two types of mechanisms. First, after applying hydrogen to dissolve hydrogen until it becomes supersaturated, a portion (flow channel) where no pressure is applied to the subsequent flow channel (tube) is provided, and the excess pressure is maintained by keeping the pressure lowered. Excess hydrogen can be separated by allowing the hydrogen to pass through a pipe long enough to separate (further, it is preferable to provide a hydrogen-dissolved water storage tank described later and discharge the surplus hydrogen there). Excess hydrogen gas may be appropriately discharged from an exhaust valve or the like, or may be sent to the hydrogen mixing unit for reuse.

  As another method, after hydrogen is supersaturated, it is allowed to stand without applying pressure for a certain period of time, so that excess hydrogen can be separated. In this case, it is preferable to provide a stationary tank (hydrogen-dissolved water storage tank). Furthermore, a pressure gauge may be installed in the stationary tank, and when a certain pressure is reached, hydrogen gas may be discharged into the atmosphere or the like, or sent to a hydrogen mixing unit for reuse. Alternatively, a hydrogen dissolved water level meter may be installed so that hydrogen gas is released when the pressure of the hydrogen gas increases and the water level of the hydrogen dissolved water drops below a certain level.

Moreover, it is preferable to design the flow path so that it can be circulated when dissolving hydrogen at a high pressure, and to circulate it many times until it becomes supersaturated. By circulating the flow path in a high-pressure state, hydrogen is oversaturated, then left in a hydrogen-dissolved water storage tank for a certain period of time, and after excess hydrogen gas is released, it is used as a dialysate and dialysis stock solution. An appropriate hydrogen concentration can be realized.
A long flow path is desirable for dissolving hydrogen under pressure. For that purpose, a longer flow path can be ensured by spiraling the tube through which the liquid passes.

  As one embodiment of the present invention, the hydrogen-dissolved water production apparatus is an apparatus for producing a reduced dialysate stock solution having a lower oxidation-reduction potential by dissolving hydrogen gas in the dialysate stock solution. The apparatus for producing hydrogen-dissolved water is directed from the supply side (upstream side) of the dialysate stock solution (hereinafter simply referred to as “stock solution”) to the discharge side (downstream side) of the reduced dialysate stock solution in which hydrogen gas is dissolved. The filtration unit 10, the first pump 30, the hydrogen dissolving means 40, and the surplus hydrogen removing means 50 are connected in this order (FIG. 1). A hydrogen-dissolved water storage tank may be provided to separate excess hydrogen. Further, a flow path for sending hydrogen gas generated from a water electrolysis device (hydrogen generation unit 100), which is an example of a hydrogen gas supply unit, toward the pump 30 by a pump 20 is connected upstream of the hydrogen dissolving unit.

  The pump 30 is not particularly limited as long as the pump 30 can feed the filtered raw water and hydrogen mixture under pressure, and for example, a diaphragm pump, a vortex pump, a gear pump, a magnet pump, or the like can be used. In short, any pump can be used as long as it does not easily cause air-engagement and does not corrode.

The diaphragm pump is characterized in that it is fed as a pulsating flow under pressure and that air-engagement idling is less likely to occur and can be suitably used in the present invention.
The pump may be a single head or a double head. A double-head pump has the advantage that the device can be made more compact.

  Hereinafter, the hydrogen dissolved water production apparatus on the upper side of FIG. 2 will be described, but the lower B raw water in FIG. 2 has basically the same mechanism. FIG. 2 is a type capable of continuous operation. The filter contained in the A raw water nozzle 10 has a function of filtering particulate matter contained in the raw solution. If the stock solution has already been filtered or tap water, etc., it is not necessary to provide a high-performance filter in the dialysate / stock solution hydrogen reduction device, and a corrosion-resistant wire mesh or mesh to remove solids. But you can. When the stock solution is not filtered, it is preferable to provide a filter for filtration. The filter may be of any form as long as it can separate unnecessary solids or the like, but a cartridge-type filter or a dust-removing mesh is preferably used. When it is necessary to remove bacteria and endotoxin, a membrane module such as a hollow fiber or a reverse osmosis membrane (RO membrane) may be used as a filter.

  The stock solution passes through the pipe and enters the raw water nozzle 10 where it is filtered and enters the first pump W.P. 30 through the pipe 11 from the filter. The pipe may have a narrow-diameter member (drawing joint) having a function of narrowing the inner diameter of the pipe inside. In this case, the suction side region immediately before the first pump 30 can be set to a negative pressure, and thereby deaeration can be performed. However, in the configuration of the present invention, it is not always necessary to set the intake side region to a negative pressure. This is because in the process of circulating at high pressure, hydrogen is dissolved in the liquid until it becomes supersaturated, and unnecessary nitrogen and the like are expelled during that time.

  As shown in FIG. 2, the hydrogen-dissolved water production apparatus of the present invention uses the tube pump 20 (P01A, P01B) to generate hydrogen gas generated from the hydrogen generator 100, for example, for each of the A liquid side and the B liquid side. Pumped at a flow rate of 6 ml / min, mixed with filtered raw water (for example, flow rate 20 ml / min) using the suction pressure at the inlet of the pump 30 and then pressurized by the double head diaphragm pump 30 (WP). From the pump outlet, in a spirally wound hose 40, the state of mixing of the solution and hydrogen is increased and a part is circulated back through the terminals 41 and 45 and before the hydrogen injection point, while the other 42, 50, 52 is discharged into a hydrogen-dissolved water storage tank 60 to which a suction nozzle of a personal dialyzer is connected. As the hydrogen-dissolved water storage tank, for example, a tube container or the like is preferably used, but is not limited thereto. Alternatively, hydrogen-dissolved water may be circulated through the flow path 62 from the bottom joint 61 of the hydrogen storage tank.

  At the time of discharge to the hydrogen-dissolved water storage tank, surplus hydrogen is gas-liquid separated and accumulates in the upper part of the hydrogen-dissolved water storage tank, so that the pressure of hydrogen gas increases and the liquid level in the container decreases. When the liquid level is below a certain value by the liquid level sensor 80, the exhaust tube pump 90 (P02A, P02B) is operated to have a mechanism for exhausting surplus hydrogen in the container. Excess hydrogen and waste water are discharged from the drain 130. Further, water vapor generated from the hydrogen generator is discharged from 130. A part of the surplus hydrogen may be sent to a hydrogen generator, and may be combined with hydrogen produced by the hydrogen generator to be used for hydrogen dissolved water production. In this case, it can be realized by adding one branch line from the drain (exhaust) line. As a method for returning this part, it is also possible to change the diameter of the line tube.

  In the present invention, the apparatus is made compact by disposing the hose in a spiral shape and not using the hollow fiber membrane. Moreover, since a hollow fiber membrane is not used, there is an advantage that bacteria are not generated on the membrane.

  The hydrogen dissolving means is means for dissolving hydrogen by applying pressure to the stock solution. It is preferable to use a spiral tube to lengthen the flow path. A throttle joint is installed downstream, and high pressure (0.131325 to 0.501325 pascal) is applied by a pump. Thereby, hydrogen gas melt | dissolves in a liquid and supersaturated hydrogen-dissolved water is manufactured. The throttle joint can be formed by, for example, passing a tube having an inner diameter of 1 mm and an outer diameter of 3 mm through a tube having a diameter (inner diameter) of 3 mm. The length of the throttle joint is preferably 5 to 30 mm, and more preferably 10 to 25 mm. Depending on the solution used, the upper limit of the length of the throttle joint may be 20 mm or less and 15 mm or less.

  The raw water and hydrogen gas are mixed by the diaphragm pump 30 (W.P.), pressurized, and the hydrogen gas dissolves in the raw water while passing through the line 40, resulting in a supersaturated state. When moving from the throttle joint 45 to 42, the pressure decreases and excess hydrogen gas begins to escape (gas-liquid separation). As the supersaturated hydrogen-dissolved water passes through the 50 spiral tubes, excess hydrogen gas is released and then stored in the hydrogen-dissolved water storage tank 60. Part of the stored hydrogen-dissolved water merges with the flow path 12 through the flow path 62 and is mixed with hydrogen, and is pressurized by the pump 30 to further dissolve the hydrogen. With this circulation mechanism, supersaturated hydrogen-dissolved water can be produced more reliably, and high-concentration hydrogen water can be supplied stably.

  In the hydrogen-dissolved water storage tank, excess hydrogen is stored as a gas on the upper side, and the water level of the hydrogen-dissolved water is lowered by the pressure of the hydrogen gas. The drop in the water level is detected by the level meter 80, and when it becomes lower than a predetermined height, hydrogen gas is discharged by the pump 90 (130). A part of the hydrogen gas may be mixed with the hydrogen gas generated by the hydrogen generator 100 and mixed with the raw water by the diaphragm pump 30.

  The hydrogen generator 100 electrolyzes pure water coming from the pure water tank 110 to generate hydrogen and oxygen, and uses the hydrogen for producing hydrogen-dissolved water. Hydrogen generated by the hydrogen generator 100 is sent by the pump 20 through the path 21, joins the filtered raw water, and enters the path 12. Thereafter, the diaphragm pump 30 feeds the liquid while applying pressure.

  FIG. 3 shows an intermittent operation apparatus according to another embodiment of the present invention. The raw water entered from the raw water nozzle 10 passes through the flow path 12 and is mixed with hydrogen gas by the diaphragm pump 30 and passes through the spiral pipe of the flow path 40 under pressure, during which the hydrogen gas dissolves in the raw water. To do. Thereafter, after passing through the throttle valve 45, it passes through 46 and enters a hydrogen storage tank. When a predetermined amount of hydrogen-dissolved water is stored, the liquid feeding is stopped. Thereby, excess hydrogen is released as a gas in the hydrogen-dissolved water storage tank 60. When the hydrogen gas is released and the pressure in the hydrogen-dissolved water storage tank rises and the liquid level falls, the water level sensor 80 detects a drop in the liquid level, and the pump 90 discharges the hydrogen gas. The supersaturated hydrogen-dissolved water in which hydrogen is dissolved is divided into a route to 46 and a route to 47, 48 and 49 after passing through the throttle valve 45. The routes 47, 48 and 49 are connected to the hydrogen-dissolved water storage tank 51. When the hydrogen-dissolved water storage tank becomes negative pressure and the raw water flows backward, the hydrogen-dissolved water passes through 49 → 51 → 55. It is a mechanism to prevent excessive backflow by flowing raw water into the storage tank. Reference numeral 55 denotes a joint portion of the tube. The joint is not particularly limited as long as the tube does not come off, but a joint that can be prevented from coming off with an insulation lock such as a bamboo shoot joint is preferably used. Others are similar to the continuous operation.

  The hydrogen-dissolved water of the present invention is suitably used for dialysis, but hydrogen gas may be separately sucked from the nasal cavity during dialysis. In addition to dialysis with hydrogen-dissolved water, hydrogen is supplied from the nasal cavity, so that hydrogen can be dissolved in blood and the effect of hydrogen can be obtained.

  In that case, the hydrogen generated from the hydrogen generator (H2CELL) in FIGS. 1 to 3 may be branched and supplied to the patient through the nasal cannula (see FIG. 10) from the tube. Or you may make a patient suck | inhale hydrogen gas separately separately using the hydrogen generator shown in FIG.

  When using the hydrogen-dissolved water production apparatus and hydrogen gas supply apparatus of the present invention, both apparatuses are linked so that the dialysis amount and the amount of hydrogen suction from the nasal cavity can be controlled in a balanced manner according to the patient's condition. A system that can collectively control the hydrogen supply amount may be used.

(Example 1)
FIG. 4 is an experiment for examining the time course (change over time) of the oxidation-reduction potential when hydrogen is dissolved in a liquid using the apparatus of the present invention (FIG. 2). As a mock test solution, use the same solution of NaCL (sodium chloride) as dialysate solution A on the A solution side, and use B solution (powder type of kinderial dialysate B) on the B solution side. Then, in a laboratory set at a room temperature of 25 ° C., a solution sucked by a pump serving as a dummy for a personal dialyzer was sampled in a beaker, and an oxidation-reduction potential (ORP value) was measured. The oxidation-reduction potential can be measured using, for example, a portable pH meter (model number: HM-21P) manufactured by Toa DKK. The measurement was carried out for 20 minutes (A), then the liquid was discarded for 12 minutes (B), and further the liquid was discarded for 14 minutes (C), and the oxidation-reduction potential was measured and plotted every minute. It can be seen that the redox potential decreases in the order of A, B, and C. In addition, although the redox potential on the liquid A side decreases earlier, it stops stopping on the way, so that the liquid B finally has a lower redox potential.
(Example 2)

  FIG. 5A shows the change over time of the oxidation-reduction potential when hydrogen was added to the liquid A and the liquid B, respectively, using an apparatus provided with a throttle joint for the liquid B and the liquid A. As in FIG. 4, the liquid B has a lower redox potential than the liquid A.

In FIG. 5B, hydrogenation was performed using pure water, but the test was performed in a normal state of A and B. The redox potential was almost the same.
Example 3

6A and 6B show the oxidation-reduction potential at the time of hydrogen addition measured by an apparatus different from the second and third machines. It can be seen that almost the same oxidation-reduction potential can be obtained if the devices have the same configuration.
(Example 4)

FIG. 7A shows the measurement of the oxidation-reduction potential of bubbling (commercial goldfish pump), nano engine (PCT / JP2012 / 068480), and the device of the present invention. Compared to bubbling and nanobubble generators, FIG. It can be seen that the apparatus can reduce the redox potential. FIG. 7B shows a change with time of the oxidation-reduction potential when hydrogenation is performed using the personal device of the present invention.
(Example 5)

  FIG. 8 shows the time-dependent change in oxidation-reduction potential when hydrogen-reduced water produced with the personal device of the present invention using ultrapure water was transferred to a 100 ml cup and left at room temperature at 25 ° C. Is. It can be seen that the reduced state is maintained for about 2 hours after the production, but returns to the redox potential before the reduction in about 11 hours.

Example 6 Hydrogen Supply Device FIG. 9 shows a hydrogen supply device of the present invention. The hydrogen gas generated from this apparatus can be supplied from the patient's nose by the tube and nasal cannula of FIG.

  As shown in FIG. 9, the pure water supplied from the pure water tank 210 is electrolyzed by the hydrogen generation cell and decomposed into oxygen gas and hydrogen gas. The hydrogen gas (217) containing water vapor and water is cooled by the cooling mechanism 218, and a special filter 223 provided in the hydrogen-water separation mechanism 219 (a film that transmits gas but does not transmit liquid, such as TEMISH (registered) Trademark) S-NTF1033-N06, manufactured by Nitto Denko Corporation) is separated into water 222 and hydrogen (gas) 220, and the separated hydrogen gas 221 is supplied to the patient. The water separated by the hydrogen-water separation mechanism is returned to the pure water tank 210 by the pump 226.

  In this case, pure water may be returned to the pure water tank 210 by the pump 226 when the water level detection sensor 224 becomes higher than a certain level, and the timer 225 operates the pump 226 when the timer is set and the time is reached. It may be returned to the pure water tank 210. Preferably, the water level detection sensor 224 and the timer circuit 225 may be linked to control the pump 226 with both the water level and the timer to return to the pure water tank 210.

  The level of pure water in the pure water tank is detected by a float switch (not shown) of the drought sensor 12, and hydrogen generation is stopped during drought. The hydrogen generation cell includes a hydrogen generation cell drive power supply 212. The amount of hydrogen generation is displayed by the hydrogen generator 211. Since the amount of hydrogen generation is substantially proportional to the energization current to the hydrogen generation cell, the amount of current may be converted into a hydrogen amount and displayed.

  INDUSTRIAL APPLICATION This invention can be utilized for the industry which manufactures the dialysate containing hydrogen solution water or hydrogen which manufactures a dialysate.

DESCRIPTION OF SYMBOLS 10 Filtration part 20 Pump 30 Pressure pump 40 Hydrogen dissolution part 45 Throttle valve 50 Surplus hydrogen separation part 60 Hydrogen dissolution water storage tank 61 Bottom joint 70 Liquid feed tube 80 Water level sensor 90 Pump 100 Hydrogen generation part 110 Pure water tank 120 Magnet switch 130 Drainage or Exhaust 210 Pure Water Tank 211 Hydrogen Generation Amount Display 212 Hydrogen Generation Cell Drive Power Supply 213 Pure Supply 214 Hydrogen Generation Cell 215 Pure Water + Oxygen 216 Drought Boat 217 Hydrogen + Steam + Water 218 Cooling Mechanism 219 Hydrogen-Water Separation Mechanism 220 Hydrogen 221 Hydrogen gas 222 Water 223 Special filter 224 Water surface detection sensor 225 Timer circuit 226 Pump 227 Separated water return

Claims (13)

Filtration means for filtering raw water;
Means for dissolving hydrogen in the filtered raw water;
An apparatus for producing a hydrogen-dissolved water solution, comprising: means for removing excess hydrogen from raw water in which hydrogen is dissolved; and means for supplying hydrogen.   2. The hydrogen-dissolved water production apparatus according to claim 1, wherein the means for dissolving hydrogen is means for dissolving hydrogen until hydrogen is supersaturated.   3. The hydrogen-dissolved water production apparatus according to claim 1, wherein the means for dissolving hydrogen includes a circulation means.   The hydrogen-dissolved water production apparatus according to any one of claims 1 to 3, wherein the means for removing excess hydrogen is a means for discharging hydrogen by reducing pressure.   The hydrogen-dissolved water production apparatus according to any one of claims 1 to 4, wherein the hydrogen-dissolved water is a dialysis solution or a dialysis stock solution. Filtering raw water to produce filtered water;
Mixing hydrogen into filtered water and applying pressure to dissolve hydrogen;
Removing excess hydrogen from filtered water in which hydrogen is dissolved;
A method for producing hydrogen-dissolved water having:   The method for producing hydrogen-dissolved water according to claim 6, wherein the step of dissolving hydrogen is a step of dissolving hydrogen until hydrogen becomes supersaturated.   The method for producing hydrogen-dissolved water according to claim 6 or 7, wherein the means for dissolving hydrogen includes a circulation step.   The method for producing hydrogen-dissolved water according to any one of claims 6 to 8, wherein the step of removing excess hydrogen is a step of releasing hydrogen by reducing pressure.   The method for producing hydrogen-dissolved water according to claim 6, wherein the hydrogen-dissolved water is a dialysis solution or a dialysis stock solution.   A hydrogen gas supply device comprising a pure water tank, a hydrogen generation cell, a cooling mechanism, a hydrogen-water separation mechanism, and a pump.   The hydrogen gas supply device according to claim 11, wherein hydrogen and water are separated by a special filter.   A method for supplying hydrogen gas by the hydrogen gas supply device according to claim 11.