JP2019071904A - Three-dimensional structure containing volatile chemical - Google Patents

Abstract

To secure a surface area even if reducing a size of an entire structure containing volatile chemical and thereby suppress an amount of volatilization decrease of the volatile chemical, and reduce a portion coming into contact with the inner wall of a container out of the surface area of the entire structure as much as possible to thereby avoid the volatilization of the volatile chemical from being obstructed and prevent the contamination of the container.SOLUTION: A three-dimensional structure is characterized in that a resin composition containing the volatile chemical having volatilization properties is formed in a shape of a flat plate. The three-dimensional structure has through-holes penetrated from the front to the back face, and the peripheral edges of the through-holes have shapes selected from polygonal shapes, circular shapes, circular arc shapes and spiral shapes when the three-dimensional structure is viewed from the front. The peripheral shapes of the through-holes have shapes formed in coplanar or continuously changing surfaces.SELECTED DRAWING: Figure 2

Description

  The present invention relates to a steric structure containing a volatile drug.

  In a house, windows and entrances become entrances for pests. It is conceivable to dispose insect repellents at these places as a method of suppressing the infestation of pests from the ingress to this.

  As an example of such an insect repellent, an insect repellent having a volatile repellent held in a net and housed in a container having an open window, or an insect repellent having a net holding a volatile chemical incorporated in a frame member A tool (refer patent document 1) etc. are known.

JP, 2006-314284, A

  By the way, although these insect repellents are often suspended and used by a window, a front door, etc., in this case, they may feel in the way of a moth repellent, or they may be disturbed. In order to solve this problem, it is conceivable to reduce the presence of the insect repellent by reducing the size or thickness of the entire insect repellent.

  However, in order to reduce the size or thickness of the entire insect repellent, it is necessary to make the net holding the insect repellent in the insect repellent smaller, as a result, the amount of volatilization of the insect repellent is reduced. With this, the repellent effect will be reduced.

  In addition, when a net containing a volatile drug is stored in a container and used, the volatile drug volatilizes from the surface of the net, but if there are many portions of the total surface area of the net that contact the inner wall of the container, the volatilization The volatilization of the drug may be impeded to reduce the amount of volatilization, or the volatilizable drug adhering to the inner wall may cause contamination of the container.

  By the way, this problem may cause similar problems such as reduction of the amount of volatilization and contamination even when using a repellant, a fragrance, an antibacterial agent or the like other than the insect repellent agent.

  Therefore, according to the present invention, even if the size of the entire structure containing the volatile drug is reduced, the surface area is secured to suppress the decrease in the amount of volatilization drug volatilized, and the inner wall of the container among the surface area of the entire structure. It is an object of the present invention to reduce the number of parts that can come into contact with the container as much as possible and to prevent the volatilization of the volatilization agent from being prevented while preventing the container from being contaminated.

  The present invention is a three-dimensional structure formed by molding a resin composition containing a volatilizing agent having volatilization into a flat plate shape, the three-dimensional structure having a through hole penetrating from the front to the back, and the three-dimensional structure When the structure is viewed from the front, the peripheral edge of the through hole has a shape selected from a polygonal shape, a circular shape, an arc shape and a spiral shape, and the peripheral shape of the through hole is coplanar or continuous. The above problem is solved by using the volatile drug-containing three-dimensional structure having a shape formed on the changing surface.

Since the volatile drug-containing three-dimensional structure according to the present invention is a three-dimensional structure, the surface area within a certain range is increased as compared with the case of a substantially planar net. Therefore, even if the overall size is reduced, the surface area capable of volatilizing the volatilizing agent can be secured, and the volatilization amount of the volatilizing agent can be maintained.
Furthermore, since it has a through-hole penetrating from the front to the back, by aligning the flow of the drug to be volatilized in a certain direction to make it easy to generate an air flow, the drug with high concentration is collected in the target direction to enhance the insecticidal effect. Can.
In addition, since it has a three-dimensional structure, the portion of the volatile drug-containing three-dimensional structure in contact with the container can be reduced, and the decrease in the volatilization drug volatilization amount and the contamination of the container caused by the contact with the inner wall of the container can be suppressed. Is possible.

(A) a perspective view showing an example of a three-dimensional structure, (b) a front view of (a), (c) a side view of (a), (d) an end view of (a), (e) (b) ee sectional drawing, (f) ff sectional drawing of (b) (A) a perspective view showing another example of the three-dimensional structure, (b) a front view of (a), (c) a side view of (a), (d) an end view of (a), (e) (b) Ee) cross-sectional view of (f) and (b) (A) a perspective view showing another example of the three-dimensional structure, (b) a front view of (a), (c) a side view of (a), (d) an end view of (a), (e) (b) Ee) cross-sectional view of (f) and (b) (A) a perspective view showing another example of the three-dimensional structure, (b) a front view of (a), (c) a side view of (a), (d) an end view of (a), (e) (b) Ee) cross-sectional view of (f) and (b) ff cross-sectional view of (g) and (g) g-g cross-sectional view (A) a perspective view showing another example of the three-dimensional structure, (b) a front view of (a), (c) a side view of (a), (d) an end view of (a), (e) (b) E) cross section of (A) a perspective view showing another example of the three-dimensional structure, (b) a front view of (a), (c) a side view of (a), (d) an end view of (a), (e) (a) (F) cross-sectional view of (f) and (b), cross-sectional view of (g) and (g) (A) a perspective view showing another example of the three-dimensional structure, (b) a front view of (a), (c) a side view of (a), (d) an end view of (a), (e) (a) (F) cross-sectional view of (f) and (b), cross-sectional view of (g) and (g) (A) a perspective view showing another example of the three-dimensional structure, (b) a front view of (a), (c) a side view of (a), (d) an end view of (a), (e) (a) A rear view of (f) (b) ff cross section (A) a perspective view showing another example of the three-dimensional structure, (b) a front view of (a), (c) a side view of (a), (d) an end view of (a), (e) (a) (F) cross-sectional view of (f) and (b), cross-sectional view of (g) and (g) (A) A perspective view showing another example of the three-dimensional structure, (b) a front view of (a) (A) A perspective view showing another example of the three-dimensional structure, (b) a front view of (a) (A) A perspective view showing another example of the three-dimensional structure, (b) a front view of (a) (A) A perspective view showing another example of the three-dimensional structure, (b) a front view of (a) (A) a perspective view showing another example of the three-dimensional structure, (b) a front view of (a), (c) a side view of (a), (d) an end view of (a), (e) (b) E) cross section of (B) (a) front view, (c) (a) side view, (d) (d) cross-sectional view of (d) (b) (a perspective view showing an example of a three-dimensional structure used in Reference Example 1 e) ee cross-sectional view of (b), end view of (f) (a), (g) cross-sectional view of (g) g-g, (h) cross-sectional view of (b)

  The volatilizable drug-containing three-dimensional structure according to the present invention is a three-dimensional structure obtained by forming a resin composition containing a volatilizable drug into a flat plate shape.

[Volatile drug]
The volatile chemical is not particularly limited as long as the active ingredient volatilizes at normal temperature and the active ingredient volatilizes at normal temperature, and an insect repellent, a repellent, an aromatic, a deodorant, an anti-odor A lozenge, an antibacterial agent etc. can be used.

  The above insect repellents include transfluthrin, metfluthrin, empentrin, profluthrin, allethrin, framethrin, praretrin, resmethrin, phthalthrin, phenothrin, pyrethroid insecticidal components such as natural pyrethrin, organophosphorus insecticidal components such as dichlorvos, fenitrothion, marathon, Insect growth control agents such as methoprene, hydroprene and the like, and the like are mentioned, and among them, pyrethroid insecticidal components selected from transfluthrin, metfluthrin, empentrin and profluthrin are preferable. Among these compounds, optical isomers or geometric isomers based on asymmetric carbon and unsaturated bond may exist, but it is of course that each of them or any mixture thereof is also included in the present invention. .

  Examples of the repellent agent include N, N-diethyl toluamide (diet), dimethyl phthalate, dibutyl phthalate, 2-ethyl-hexanediol, dibutyl succinate, p-menthane-3,8-diol and the like.

  As the above-mentioned fragrance, citronella oil, orange oil, lemon oil, lime oil, yuzu oil, lavender oil, peppermint oil, eucalyptus oil, jasmine oil, soy sauce, green tea essential oil, limonene, α-pinene, linalool, geraniol, phenyl Ethyl alcohol, amyl cinnamic aldehyde, benzyl acetate and the like can be mentioned.

  As the above-mentioned deodorant, as volatile ones, mention may be made, for example, of pyrethrum such as hiba oil, cypress oil, bamboo extract, bamboo extract, yomigi extract, tung oil, ethyl pyruvate, phenylethyl pyruvate and the like.

  Examples of the fungicides include 2-n-octyl-4-isothiazolin-3-one, isopropylmethylphenol and orthophenylphenol.

  Examples of the antibacterial agent include hinokitiol, tetrahydrolinalool, eugenol, citronellal, allyl isothiocyanate and the like.

[Resin composition]
Next, the resin composition which comprises said three-dimensional body is demonstrated.
This resin composition is a composition in which a resin contains a volatile drug, and is a composition capable of volatilizing the above-mentioned volatile drug contained.

The resin is not particularly limited as long as it is capable of gradually volatilizing the contained volatilizing agent from the surface as it is or when a carrier described later is used. For example, a polyolefin resin such as polyethylene (PE) such as branched low density polyethylene (LDPE) or linear low density polyethylene (LLDPE), polypropylene (PP), or a carboxylic acid ester thereof (vinyl acetate, methyl methacrylate) And polyolefin copolymers with ethyl methacrylate etc.). Such carboxylic acid esters are effective in controlling the volatilization of the volatilizing agent from the resin surface, and generally have a tendency to delay the bleeding rate of the volatilizing agent as the blending ratio of the carboxylic acid ester to the polyolefin resin increases. . In the present invention, ethylene-vinyl acetate copolymer (EVA), ethylene-methyl methacrylate copolymer (EMMA), etc., in which 1 to 35% by weight of carboxylic acid ester is blended to polyolefin resin, are suitably used Be done.
In addition, it is possible to use a polymer blend in which the content ratio of the polyolefin copolymer and the homopolymer of olefin is adjusted and mixed, and, if necessary, to contain other polymer compounds such as a styrene elastomer. You can also.
In addition, the said carboxylic acid ester means unsaturated carboxylic acid ester or carboxylic acid vinyl ester.

  In the above-mentioned resin composition, carriers such as talc, alumina, silica and white carbon may be used in combination as needed, and further, a colorant, a stabilizer, an antistatic agent and the like may be appropriately blended. If a carrier is used, it is convenient to be able to employ a manufacturing process in which a masterbatch containing a high concentration of volatile chemicals in the resin is prepared in the first step, and further diluted to a predetermined concentration using the resin in the second step. It is. In addition, communicating bubbles may be generated from the inside to the surface of the resin composition, and the internal volatilizing agent may be easily bled on the surface.

  The content of the volatile drug in the resin composition is appropriately determined depending on the type of the volatile drug to be used, the type of resin, the usage environment, the usage period, and the like. The longer the use period, the higher the content of the volatile drug, but it is appropriate to set in the range of 1 to 20% by weight. If it is less than 1% by weight, it is difficult to secure the dose necessary to exert the effect. On the other hand, if it exceeds 20% by weight, molding after kneading the volatile drug becomes difficult, and the resin surface is further deteriorated. In some cases, the volatilization drug may bleed excessively to cause stickiness.

  When the above carrier is used, the amount of use of the carrier in the resin composition is preferably 5 parts by weight or more, and preferably 10 parts by weight or more, with respect to 100 parts by weight of the volatile drug to be used. If the amount is less than 5 parts by weight, the ability to retain the volatile drug will be poor and production by the masterbatch will be difficult. On the other hand, the upper limit of the amount of carrier used is preferably 50 parts by weight, preferably about 35 to 40 parts by weight with respect to 100 parts by weight of the volatile drug. If it is more than 50 parts by weight, the strength of the steric structure and the bleeding property of the volatile drug may be affected.

  The volatile drug-containing three-dimensional structure according to the present invention can be molded by subjecting the above resin composition to injection molding or the like. The injection molding conditions can be performed under well-known conditions in consideration of the type of resin to be used, the blending ratio of each component, and the like.

In the resin composition, the volatile drug bleeds onto the surface of the volatile drug-containing three-dimensional structure, and is volatilized from the surface, so when the volatile drug-containing three-dimensional structure is touched, the volatile drug There is a risk of sticking to the hand. Therefore, it is preferable to use the volatile drug-containing three-dimensional structure according to the present invention in a container. This container is not particularly limited as long as it is difficult to touch the internal volatilizable drug-containing three-dimensional structure and there is a hole (open window) to such an extent that the volatilizable drug is easily volatilized. Moreover, it is preferable that this container has a structure which can be hung or attached to a screen door or the like according to the usage.
In addition, the volatilizable drug-containing three-dimensional structure of the present invention is stronger than the net shape, and also has an advantage of being able to be stored in a container smoothly in the manufacturing process.

[3D structure]
Next, the three-dimensional structure which shape | molded the said resin composition is demonstrated.
This three-dimensional structure is formed into a flat plate shape, and has a through hole penetrating from the front to the back. The surface area of the three-dimensional structure can be increased by the through holes, and the amount of volatilization of the drug can be increased, and the flow of the drug to be volatilized can be aligned in a certain direction to easily generate an air flow. The high drug can be collected in the desired direction to enhance the insect repellent effect.

  The peripheral edge of the through hole has a triangular shape, a quadrangular shape, a pentagonal shape, a hexagonal shape, a polygonal shape such as an octagonal shape, a circular shape such as a perfect circle shape, an oval shape, or an arc shape when the three-dimensional structure is viewed from the front. And forms a spiral shape or the like. And the shape of the periphery of the through hole is the shape formed in the same plane or the field which changes continuously. This makes it possible to simultaneously exhibit the features of design, ease of molding, and expansion of the volatilization of the volatilizing agent.

  It is preferable that such a through hole is provided such that the concealing rate when viewed from the front or the side of the three-dimensional structure is within a predetermined range, from the viewpoint of expansion of the volatilization of the volatilizable drug. The hiding ratio when viewed from the front of the three-dimensional structure is preferably 5% or more, and preferably 10% or more. If it is less than 5%, not only the formation of the three-dimensional structure becomes difficult, but also the strength of the structure itself may be reduced. On the other hand, the upper limit of the concealment rate when viewed from the front is preferably 50%, preferably 40%. If it is more than 50%, it may be difficult to align the flow of medicine in a certain direction.

  Further, the hiding ratio when viewed from the side of the three-dimensional structure is preferably 50% or more, and preferably 80% or more. If it is less than 50%, it may be difficult to align the flow of medicine in a certain direction. On the other hand, since the side surface does not need to have a through hole, the upper limit of the concealing rate when viewed from the side is 100%.

As an example of such a three-dimensional structure, the structure of the following FIGS. 1-14 is mentioned.
If the peripheral edge of the through hole has a specific shape, the peripheral edge of the specific shape through hole and the peripheral edge of the adjacent through hole having the same shape, or between the outer peripheral edge of the three-dimensional structure The periphery of the through-hole of the shape which is not a specific shape may arise. This is because depending on the shape of the peripheral edge of the through hole, it is not possible to fill the entire front face of the three-dimensional structure with that shape, and a remaining portion is generated. In the following, the shape of the remaining portion is not particularly mentioned, but the presence or absence of the remaining portion can be determined from each drawing or the like.

First, in the three-dimensional structures 11a to 11e shown in each of FIGS. 1 to 5, the shapes of the peripheral edges 13a to 13e of the through holes 12a to 12e are held constant from the front to the back of the three-dimensional structures 11a to 11e. It is. In the thickness direction, the outer peripheral edges 14a to 14e of the three-dimensional structure and the peripheral edges 13a to 13e of the through holes 12a to 12e are all flat. And this thickness direction length has a thickness about self-supporting (can be erected without a support) when this surface is turned down, in that it becomes easy to arrange the flow of medicine in a fixed direction preferable.
In each of FIGS. 1 to 5, the shapes of the peripheral edges 13a to 13e of the through holes 12a to 12e are an equilateral triangle (FIG. 1), a square (FIG. 2), an equilateral hexagon (FIG. 3), and a perfect circle (FIG. 4). And a plurality of triangles (FIG. 5).

The three-dimensional structure 11f shown in each drawing of FIG. 6 can be formed by shaping the rod-like body of the resin composition as the shape of the through hole 12f (that is, the shape of the peripheral edge 13f of the through hole). It is a structure which has the through-hole formation part 15f. A plurality of the through hole forming portions 15f are arranged on the same plane and connected to each other to constitute a front portion of the three-dimensional structure. And, a rod-like body is connected to the plurality of through-hole forming parts 15f, and a large number of legs 16f are formed, and the end edge part of the leg 16f consisting of the rod-like body constitutes the back face of the three-dimensional structure. Do. Therefore, the three-dimensional structure shown in FIG. 6 is flat as a whole.
In each of FIGS. 6A and 6B, a square is exemplified as the shape of the through hole 12f (the shape of the peripheral edge 13f of the through hole), that is, the shape of the through hole forming portion 15f.

In the three-dimensional structures 11g and 11h shown in FIGS. 7 and 8, circular or polygonal holes are made in the plate-like members 17g and 17h, and one surface of the plate-like members is covered so as to cover the holes. The cover portions 18 g and 18 h are provided on the other side or both sides. For this reason, the three-dimensional structure shown to each figure of FIG. 7, 8 becomes flat form as a whole. The cover portions 18g and 18h are surfaces projecting from the plate-like members, and when the plurality of plate-like members are stacked, the cover portions 18g and 18h refer to a shape portion in which the projecting surfaces overlap.
The cover portions 18g and 18h have a shape obtained by cutting a true sphere or an ellipsoid, a hemispherical shape, a dome shape, a prism having a shape such as a triangular prism, a quadrangular prism, a hexagonal prism, etc. And hollow bodies having a frustum shape having a frustum shape such as a pyramid frustum such as a triangular frustum, a quadrangular frustum or a hexagonal frustum, or a frustum shape. Then, the bottom surface is opened, and the inside of the cover portion communicates with the hole of the plate-like body.
Furthermore, the through holes 12g and 12h are provided in portions other than the cover portion and the holes of the plate-like body. The shape of the through hole may be linear as well as the above-described shape.
In each of FIGS. 7 and 8, the shape of the hole of the plate-like member is a true circle, and the shape of the cover portion is a true sphere hemispherical (FIG. 7) and a truncated cone (FIG. 8). The through holes have an arc shape, a perfect circle shape, a linear shape (FIG. 7), and a perfect circle shape (FIG. 8).

A three-dimensional structure 11i shown in each drawing of FIG. 9 can be formed as a shape of the through hole (that is, a shape of a peripheral edge of the through hole) by bending a rod-like body of the resin composition. It is a structure which has the hole formation part 15i. Then, the through-hole forming portions 15i are arranged in one step, or another through-hole forming portion 15i is overlapped in a plurality of two or more steps in the through-hole forming portions 15i arranged in one step, or the like. The through hole forming portions 15i are connected directly or via a connecting member.
When the through hole forming portions 15i are stacked in multiple stages, the side edge portions of the other through hole forming portions are disposed below the holes of the through hole forming portions 15i, but they are only partially obstructive.
In each of FIGS. 9A and 9B, a rectangle is exemplified as the shape of the through hole (the shape of the periphery of the through hole), that is, the shape of the through hole forming portion 15i.

The three-dimensional structures 11j, 11k, 11m, and 11n shown in the respective drawings of FIGS. 10 to 13 are intersections of one surface of lattice bodies 19j, 19k, 19m, and 19n having a structure in which a plurality of rod-like bodies intersect in a lattice shape. In this structure, legs 16j, 16k, 16m and 16n made of rod-like members are connected at right angles to the one surface. And, in the rod-like body between the intersection of the lattice and the adjacent intersection, the projections 20j, 20k, 20m, or the like on the one surface, the surface opposite to the one surface, or both surfaces. 20 n are formed.
The projection is a rod-like body or a plate-like body which is formed into a predetermined shape. Examples of this shape include a polygonal shape, and a shape obtained by cutting a part of a true circle or an ellipse.
In each of FIGS. 10 to 11, the protrusions 20j and 20k are disposed on the one side, and in each of FIGS. 12 to 13, the protrusions 20m and 20n are on both sides. An example is provided. In each of FIGS. 10 and 12, the protrusions 20j and 20m exemplify a trapezoidal plate-like body, and in each of FIGS. 11 and 13, the protrusions 20k and 20n have a trapezoidal shape. What formed the external shape with the rod-shaped body is illustrated.
Furthermore, although the protrusions 20m and 20n disposed on both surfaces in each of FIGS. 12 to 13 are the same, they may be different.

  A three-dimensional structure 11p shown in each drawing of FIG. 14 is a structure having a shape in which a spiral through hole 12p is formed in a plate-like body 17p and a central portion of the spiral is lifted upward. For this reason, the plate-like body 17p will form the surface where height changes continuously, and as a structure, it will have thickness and it will become a three-dimensional structure.

The volatile drug-containing three-dimensional structure according to the present invention can be manufactured by subjecting the above-mentioned resin composition to molding processing such as injection molding, deformation, bending, bonding and the like. These conditions can be performed under well-known conditions in consideration of the type of resin to be used, the blending ratio of each component, and the like.

In the resin composition, the volatile drug bleeds onto the surface of the volatile drug-containing three-dimensional structure, and is volatilized from the surface, so when the volatile drug-containing three-dimensional structure is touched, the volatile drug There is a risk of sticking to the hand. Therefore, it is preferable to use the volatile drug-containing three-dimensional structure according to the present invention in a container. This container is not particularly limited as long as it is difficult to touch the internal volatilizable drug-containing three-dimensional structure and there is a hole (open window) to such an extent that the volatilizable drug is easily volatilized. Moreover, it is preferable that this container has a structure which can be hung or attached to a screen door or the like according to the usage.
In addition, the volatilizable drug-containing three-dimensional structure of the present invention is stronger than the net shape, and also has an advantage of being able to be stored in a container smoothly in the manufacturing process.

  The volatile drug-containing three-dimensional structure according to the present invention is housed in the above container, suspended, affixed to a screen door or the like, or allowed to stand, depending on the volatile drug used, an insect repellent It can be used as an insect repellent, a fragrance, a deodorant and the like.

  Hereinafter, the present invention will be more specifically described using examples. The present invention is not limited to the following examples unless it exceeds the gist.

Example 1
An experiment was conducted using a volatile drug-containing three-dimensional structure formed from the three-dimensional structure shown in FIG.
First, 50 parts by weight of transfluthrin (manufactured by Sumitomo Chemical Co., Ltd.) as a volatile chemical, 18 parts by weight of white carbon (manufactured by EVONIK: Carplex # 80, average particle size: 15 μm), ethylene-vinyl acetate copolymer (Tosoh Corp .: Ultracene 710, content of vinyl acetate in copolymer: 28%) 20 parts by weight, and LDPE (Asahi Kasei Corp .: Suntec LDM 6520) 12 parts by weight at 120 to 140 ° C. It knead | mixed and manufactured pellet-form masterbatch.
Next, 100 parts by weight of the obtained pellets and 300 parts by weight of the LDPE are kneaded at 120 to 140 ° C., and the obtained resin composition is injection-molded and joined, and the volatilization comprising the three-dimensional structure shown in FIG. The drug-containing steric structure (10 g) was obtained.
The size of the entire volatile drug-containing three-dimensional structure was 95 mm × 160 mm × 12 mm. The surface area of this volatile drug-containing three-dimensional structure was 90,800 mm ² .
The resulting volatile drug-containing three-dimensional structure was suspended in a room, and the amount and time of volatilization of the volatile drug were measured under the conditions of 25 ° C. and a wind speed of 0.5 m. The volatilization amount and the volatilization time were measured by measuring the weight of the volatilizable drug-containing three-dimensional structure with time.
As a result, the volatilization time was about 200 days, and the average volatilization amount over the entire period was 5.8 mg / day.

(Comparative example 1)
The resin composition obtained in Example 1 was injection-molded to obtain a cylindrical net having a rhombus-shaped net (4.8 g). This net has a thickness of 0.7 mm in outer diameter and a mesh size of 4 mm × 4 mm, and the overall size when the tubular shape is held flat is 80 mm × 150 mm (cut and spread on one side The width of the sample was 160 mm × 150 mm) and about twice the size of Example 1. The surface area of this volatile drug-containing three-dimensional structure was 20400 mm ² .
The amount of volatilization of the volatilizable agent and the volatilization time were measured in the same manner as in Example 1 for the obtained net.
As a result, the volatilization time was about 200 days, but the average volatilization amount over the entire period is 2.
In order to obtain the volatilization amount equivalent to that of the volatile drug-containing steric structure of the present invention at 9 mg / day, it is necessary to make the net large or heavy, which makes product design difficult Was expected to accompany.

(result)
As described above, the volatilization amount of the volatilizable drug-containing steric structure of Example 1 is about twice that of the volatilization amount of Comparative Example 1, and the increase in the volatilization amount is remarkable more than expected from the surface area contrast. In addition, it has become clear that, by reducing the portion of the structure in contact with the container, it is possible to suppress the decrease in the volatilization amount of the volatile drug and the contamination of the container caused by the contact with the inner wall of the container.

(Reference Example 1)
The method described in Example 1 except using metfluthrin (manufactured by Sumitomo Chemical Co., Ltd .: Eminence) as the volatilizing agent and using a steric structure as shown in Japanese Patent No. 5547350 (FIG. 15) The volatile drug-containing three-dimensional structure was produced according to
The volatile drug-containing three-dimensional structure is suspended indoors, and the wind is applied to the front or side of the volatile drug-containing three-dimensional structure under conditions of 25 ° C. and a wind speed of 0.5 m / s for 30 days The amount of volatilization of the drug was measured by weight loss of the volatilizable drug-containing three-dimensional structure, and the amount of volatilization per unit time (mg / h, mg / day) was calculated. The results are shown in Table 1.

(Examples 2 to 11)
A volatile drug-containing three-dimensional structure is produced in the same manner as in Reference Example 1 except that the three-dimensional structure shown in FIGS. 1 to 9 and 14 is used as a three-dimensional structure, and the volatilization amount of the volatile drug (mg / mg h, mg / day) was calculated. The results are shown in Table 1.

[result]
In each of Examples 2 to 11, the amount of chemical volatilization when the wind was applied to the front was higher than that of Reference Example 1. On the other hand, the volatilization amount on the side was slightly lower in Examples 2 to 11 than in Reference Example 1. And the average of the amount of volatilization of the side and the front was equivalent in reference example 1 and examples 2-11.
Therefore, both the reference example 1 and the examples 2 to 11 were able to exhibit a sufficient amount of volatilization. Moreover, it turned out that Examples 2-11 can collect a high concentration medicine to the object direction. This is expected to enhance the insect repellent effect at the target location.

11a to 11k, 11m, 11n, 11p Three-dimensional structures 12a to 12h, 12p Through holes 13a to 13f Through holes peripheral edges 14a to 14e Outer peripheral edges 15f, 15i Through hole forming portions 16f, 16j, 16k, 16m, 16n Legs 17g , 17h, 17p Plates 18g, 18h Covers 19j, 19k, 19m, 19n Lattices 20j, 20k, 20m, 20n Protrusions

Claims (1)

A spiral through hole is formed in the plate-like body,
It comprises a structure having a shape that holds a state in which a portion of the plate-like body at the center of the spiral is lifted upward,
Amount of volatilization of metfluthrin (mg / h) for 30 days under conditions of 25 ° C and wind speed of 0.5 m, which is the amount of volatilization when the wind is applied to the front and the volatilization amount when the wind is applied to the side A volatile drug-containing three-dimensional structure having a ratio (frontal volatilization amount / side volatilization amount) of more than 1.00 and 1.56 or less .

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