JP2019030614A - Hydrogen gas suction apparatus for clinical study for demonstrating therapeutic effect of hydrogen gas - Google Patents

Hydrogen gas suction apparatus for clinical study for demonstrating therapeutic effect of hydrogen gas Download PDF

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JP2019030614A
JP2019030614A JP2017161624A JP2017161624A JP2019030614A JP 2019030614 A JP2019030614 A JP 2019030614A JP 2017161624 A JP2017161624 A JP 2017161624A JP 2017161624 A JP2017161624 A JP 2017161624A JP 2019030614 A JP2019030614 A JP 2019030614A
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hydrogen gas
hydrogen
water
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里香 稲葉
Rika Inaba
里香 稲葉
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Abstract

To provide a hydrogen gas suction apparatus for clinical study for demonstrating a therapeutic effect of hydrogen gas.SOLUTION: Highly pure hydrogen gas generated by using a capsule 1 for adjusting a reaction rate of CaHis guided to a metering tank 6 so that a hydrogen gas suction amount and the hydrogen gas concentration of suction gas can be actually measured.SELECTED DRAWING: Figure 2

Description

技術の分野Technology field

２０１６年１１月３０日、水素ガス吸引療法が厚生労働省の先進医療Ｂに認定されたのに伴って、予防医療の面に重点を置いた医学が今大きく前進しようとしている。本発明は、この最近注目されている予防医療の分野の技術に関するものである。  On November 30, 2016, as hydrogen gas inhalation therapy was certified as Advanced Medicine B by the Ministry of Health, Labor and Welfare, medicine with an emphasis on preventive medicine is now making great progress. The present invention relates to a technique in the field of preventive medicine which has recently been attracting attention.

人口の高齢化がクローズアップされている今日、水素ガスが予防医療に効果があると言われるようになって、水素水や水素ガス吸引器具類が日常的に目につくようになってきた。  Today, when the population is aging, hydrogen gas is said to be effective in preventive medicine, and hydrogen water and hydrogen gas suction devices have come to be noticed on a daily basis.

特に、厚生労働省の認定以来、電気分解で発生させた水素ガスを、鼻に装着したノズルや口に当てたマスクで吸引する器具が急に増えたように思われるが、これらには医学論文や臨床研究には使用できないという問題があって、今一つ工夫が必要である。  In particular, since the approval of the Ministry of Health, Labor and Welfare, there seems to be a sudden increase in the number of instruments that suck in hydrogen gas generated by electrolysis using a nozzle attached to the nose or a mask applied to the mouth. There is a problem that it cannot be used for clinical research, so another contrivance is necessary.

今回認定された水素ガス吸引療法は、心停止後症候群（心停止して後、自己心拍が再開したが、その後も昏睡状態が持続している患者）を対象にしたものである。また、治療条件は、安全を考慮して水素濃度が２％の酸素を１８時間人工呼吸器で吸入したと限定している。  The hydrogen gas aspiration therapy approved this time is intended for post-cardiac arrest syndrome (patients whose self-beating has resumed after cardiac arrest but have continued coma). Further, the treatment condition is limited in consideration of safety, in which oxygen with a hydrogen concentration of 2% is inhaled by a ventilator for 18 hours.

この認定から学ぶことは下記の四つである。
１．水素は脳細胞の活性化に有効であること。
２．水素ガス濃度が２％の酸素を１８時間吸入しても脳に悪影響を及ぼさないこと。
３．水素ガス濃度が治療効果に影響すること。
４．認定は心停止後症候群に対するもので、市販されている水素ガス吸引器などの治療効 果を認定したものではない。認定にはそれぞれについて臨床研究が必要であること。
水素ガス吸引器の開発はこれらのことを考慮して実行されなければならない。There are four things to learn from this certification:
1. Hydrogen is effective in activating brain cells.
2. Inhalation of oxygen with a hydrogen gas concentration of 2% for 18 hours should not affect the brain.
3. The hydrogen gas concentration affects the therapeutic effect.
4). The accreditation is for post-cardiac arrest syndrome, not a therapeutic effect such as a commercially available hydrogen gas aspirator. Accreditation requires clinical research for each.
The development of a hydrogen gas aspirator must be carried out in consideration of these points.

先ず、吸引した水素ガスの濃度について考えて見る。これについては、安全を考慮して２％としてあるが、これは水素ガス濃度が４％になると爆発の危険があるのを避けるためのものである。危険がなければ濃度は高い方が良い。１％よりも２％が、それ以上でも良いということがこの表現から推測することができる。  First, consider the concentration of the sucked-in hydrogen gas. This is 2% in consideration of safety, but this is to avoid the danger of explosion when the hydrogen gas concentration reaches 4%. If there is no danger, a higher concentration is better. It can be inferred from this expression that 2% is better than 1%.

推測の理由はこうである。毛細血管と組織細胞間のＯ２とＣＯ２ガスのやりとりは、毛細血管と細胞間のＯ２の濃度差、及びＣＯ２の濃度差による拡散で行われるものである。Ｈ２も同様で、Ｈ２のやりとりは濃度差による拡散で行われているはずで、細胞に供給されるＨ２の量と供給速度はＨ２の濃度差に依存している、とするのが科学的に妥当な判断だと言える。従って、水素濃度の上限値と下限値をどこに設定するか、これは医学論文や臨床研究で避けて通れない重要な課題である。The reason for the guess is this. The exchange of O 2 and CO 2 gas between the capillary and the tissue cell is performed by diffusion due to the difference in O 2 concentration between the capillary and the cell and the difference in CO 2 concentration. H 2 is similar, exchange of H 2 than should have been done in diffusion due to concentration difference, the amount and feed rate of H 2 fed to the cell is dependent on the concentration difference of H 2, and to Can be said to be a scientifically valid judgment. Therefore, where to set the upper and lower limits of the hydrogen concentration is an important issue that cannot be avoided in medical papers and clinical research.

濃度に限らない。水素ガスの吸引量も必要である。水素が効くと言われている病気はいろいろあるが、それ等は臨床研究で裏付けされたものではない。それぞれの患者について

Figure 2019030614
が要求される。これを明記してないと医学論文にはならない。現在市販されている水素ガス吸引方式の全部が臨床研究に向かないというのはこうした理由によるものである。It is not limited to concentration. A suction amount of hydrogen gas is also required. There are various diseases that are said to work with hydrogen, but these are not supported by clinical studies. About each patient
Figure 2019030614
Is required. If this is not specified, it will not be a medical paper. This is why all of the hydrogen gas suction systems currently on the market are not suitable for clinical research.

例えば、現在市販されている電気分解方式による吸気の水素ガス濃度は次式で算出される。

Figure 2019030614
このように見積もると、濃度は０．５３％と算出される。For example, the hydrogen gas concentration of the intake air by the electrolysis method currently marketed is calculated by the following equation.
Figure 2019030614
In this way, the concentration is calculated as 0.53%.

この水素濃度、０．５３％の分圧で毛細管から組織細胞へ拡散で水素が供給されるのか、されるとして、その量は、供給速度はどうなるか。また吸引効率が０．８で良いのか悪いのか。吸引量はどうかなど、不確定要素が多々あり、臨床研究や医学論文には不向きである。  Whether hydrogen is supplied by diffusion from capillary tube to tissue cells at this hydrogen concentration, partial pressure of 0.53%, what is the supply rate of the amount? Is the suction efficiency 0.8 good or bad? There are many uncertainties, such as how the amount of suction is, and it is not suitable for clinical research and medical papers.

そこで、電気分解や化学反応で発生した水素をそのまま吸引するのではなく、一旦計量槽に導入して、水素ガスの量を確認して吸引できるようにした。  Therefore, hydrogen generated by electrolysis or chemical reaction is not sucked as it is, but once introduced into a measuring tank, the amount of hydrogen gas can be confirmed and sucked.

吸引法は、肺活量を測定する要領で深く息を吐いて、肺に残存している予備吸気と予備

Figure 2019030614
るようにした。すると吸引後、通常の呼吸をしていても、深呼吸をしなければ肺に吸い込んだ吸気の水素濃度に変化が生じない。The inhalation method is a method of measuring vital capacity, exhaling deeply, and pre-inspiration remaining in the lungs and
Figure 2019030614
It was to so. Then, even after taking a normal breath after inhalation, if you do not take a deep breath, there will be no change in the hydrogen concentration of the inhaled air inhaled into the lungs.

この吸引法によると、吸気の水素ガス濃度は次式で表される。

Figure 2019030614
According to this suction method, the hydrogen gas concentration in the intake air is expressed by the following equation.
Figure 2019030614

水素が効くと言われる病名を列挙するとこうなる。
糖尿病、ガン、白内障、肝炎、リウマチ、シミ、シワ、アレルギー、アトピー、認知症、パーキンソン病、動脈硬化、心筋梗塞、脳卒中
これらは臨床研究で裏付けされていないので、それぞれの患者について水素の治療効果を確認する必要があるが、本発明の方式によるとそれが可能である。水素の濃度も吸引量も自由に、広範囲に選定できるので、様々な条件で臨床研究を行うことができる。上記の病気のうちひとつでも良い。臨床研究で好結果が得られればそれで十分である。This is the list of disease names that are said to work.
Diabetes, cancer, cataracts, hepatitis, rheumatism, blemishes, wrinkles, allergies, atopy, dementia, Parkinson's disease, arteriosclerosis, myocardial infarction, stroke. However, according to the method of the present invention, this is possible. Since the hydrogen concentration and the amount of suction can be freely selected over a wide range, clinical research can be conducted under various conditions. It can be one of the above diseases. It is sufficient if good results are obtained in clinical research.

図１の水素発生カプセル１は、筒の一端を水が浸透する浸透材２、例えば綿で閉じて、ＣａＨ２を入れたものである。浸透材の部分を水に浸すと、滲み透った水とＣａＨ２が反応して生じたＣａ（ＯＨ）２は筒の内部に残存し、発生した高純度の水素ガスは、筒の開口部から放出されるようにしたのもである。The hydrogen generating capsule 1 in FIG. 1 is one in which one end of a cylinder is closed with a penetrating material 2 through which water penetrates, for example, cotton, and CaH 2 is placed therein. When the penetrant part is immersed in water, Ca (OH) 2 generated by the reaction between the penetrating water and CaH 2 remains in the cylinder, and the generated high-purity hydrogen gas flows into the opening of the cylinder. It was also released from.

このカプセルを、水素サーバー３に投入すると、浸透した水道水４とＣａＨ２との反応で生じた水素ガスは、水素ガス供給チューブ５を通って水素ガス計量槽６に供給される。すると、計量槽に溜めてある水が押し出されて、水面７に上下の変位が生じる。その変位で計量槽に流入した水素ガスの容積を計量して、水素ガス吸引ノズル８から適量の水素ガスを吸引できるように工夫した。When this capsule is introduced into the hydrogen server 3, the hydrogen gas generated by the reaction between the permeated tap water 4 and CaH 2 is supplied to the hydrogen gas metering tank 6 through the hydrogen gas supply tube 5. Then, the water stored in the measuring tank is pushed out and the water surface 7 is displaced up and down. The volume of the hydrogen gas flowing into the measuring tank was measured by the displacement, and it was devised so that an appropriate amount of hydrogen gas could be sucked from the hydrogen gas suction nozzle 8.

悪玉活性酸素が生じるのはストレス、ウイルス、放射線、紫外線、タバコ、排ガス、運動、その他食品添加物などによるもので、病気の８０％はこの悪玉活性酸素が関係していると言われている。  Bad active oxygen is caused by stress, viruses, radiation, ultraviolet rays, tobacco, exhaust gas, exercise, and other food additives. It is said that 80% of diseases are related to this bad active oxygen.

特に怖いのは、高齢者に特有の免疫力の衰退である。これが衰えると、悪玉活性酸素を無害にする作用も低下して、血管・血液のダメージに起因する動脈硬化、高血圧、心筋梗塞、脳卒中、冷え性が誘発されて、健康寿命の短縮を招くと言われている。  Particularly scary is the decline in immunity unique to the elderly. If this declines, the effect of harming bad active oxygen will also decline, and arteriosclerosis, hypertension, myocardial infarction, stroke, coldness due to blood vessel / blood damage will be induced, leading to a shortened healthy life expectancy. ing.

高齢者の医療費の増大で現役世代に重い負担をかけている、世界に例のない高齢化社会を迎えている今の日本に必要なのは、子供に頼る少子化対策よりも、人に頼らないで元気で、病気しないで暮らせる高齢者対策である。  Japan is now facing an unprecedented aging society, which places a heavy burden on the active generation due to an increase in medical expenses for the elderly. What is needed in Japan today is less dependent on people than measures to reduce the birthrate that rely on children. It is a measure for the elderly who can live well without illness.

日常、高齢者がお茶を汲む感覚で、適量の水素ガスが吸引できるように工夫された本発明が、高齢者の病気の治療に、健康寿命の延長に有効であることが立証されると、超高齢化社会を迎えるこれからの日本の全産業に及ぼす効果には計り知れないものがある。  When it is proved that the present invention devised so that an appropriate amount of hydrogen gas can be sucked in as if an elderly person draws tea on a daily basis is effective in the treatment of the disease of the elderly and the extension of the healthy life span. There are immeasurable effects on all Japanese industries in the future as we face a super-aging society.

浸透材を染み透った水と反応して水素（Ｈ２）と水酸化カルシウム（Ｃａ（ＯＨ）２）が生成されるようにした水素発生カプセルの断面図である。FIG. 3 is a cross-sectional view of a hydrogen generating capsule in which hydrogen (H 2 ) and calcium hydroxide (Ca (OH) 2 ) are generated by reacting with water penetrating a penetrating material. 水素サーバーからの水素で、計量槽に溜めてある水を押し出して生じた水面の変位で水素ガスの容積が計量できるようにした断面図である。It is sectional drawing which enabled the volume of hydrogen gas to be measured by the displacement of the water surface produced by pushing out the water stored in the measurement tank with the hydrogen from a hydrogen server.

１ 水素発生カプセル
２ 水が滲み透る浸透材
３ 水素サーバー
４ 水道水
５ 水素ガス供給チューブ
６ 水素ガス計量槽
７ 水面
８ 水素ガス吸引ノズルDESCRIPTION OF SYMBOLS 1 Hydrogen generating capsule 2 Osmotic material through which water permeates 3 Hydrogen server 4 Tap water 5 Hydrogen gas supply tube 6 Hydrogen gas measuring tank 7 Water surface 8 Hydrogen gas suction nozzle

Claims (2)

水素ガス発生装置から計量槽に水素ガスを供給して、計量槽に溜めてある水を排除し、その時に生じる水面の変位で水素ガスの容積を計測して、計量槽に設けてある水素ガス吸引器ノズルから適量の水素ガスが吸引できるようにした水素ガス吸引器。  Hydrogen gas is supplied from the hydrogen gas generator to the measuring tank, the water stored in the measuring tank is removed, the volume of the hydrogen gas is measured by the displacement of the water surface generated at that time, and the hydrogen gas provided in the measuring tank A hydrogen gas aspirator that can draw an appropriate amount of hydrogen gas from the aspirator nozzle. 毛細管現象で水が滲み透るように加工したカプセルにＣａＨ２（水素化カルシウム）を封入し、浸透する水の量で反応速度を調整することにより、高純度の水素ガスが持続的に供給できるようにした水素ガス供給カプセル。Capsules that have been processed so that water can penetrate and penetrate through capillarity can be filled with CaH 2 (calcium hydride), and the reaction rate can be adjusted according to the amount of water that penetrates. Hydrogen gas supply capsule.
JP2017161624A 2017-08-07 2017-08-07 Hydrogen gas suction apparatus for clinical study for demonstrating therapeutic effect of hydrogen gas Pending JP2019030614A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110898299A (en) * 2019-11-20 2020-03-24 郭俭 Portable cardiac arrest rescue machine

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110898299A (en) * 2019-11-20 2020-03-24 郭俭 Portable cardiac arrest rescue machine

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