JP2019015709A5 - Synthetic light generation method and optical property change part, light source part, measuring device, optical detection method, imaging method, functional bio-related substance - Google Patents

Synthetic light generation method and optical property change part, light source part, measuring device, optical detection method, imaging method, functional bio-related substance Download PDF

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JP2019015709A5
JP2019015709A5 JP2017235820A JP2017235820A JP2019015709A5 JP 2019015709 A5 JP2019015709 A5 JP 2019015709A5 JP 2017235820 A JP2017235820 A JP 2017235820A JP 2017235820 A JP2017235820 A JP 2017235820A JP 2019015709 A5 JP2019015709 A5 JP 2019015709A5
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optical path
light
predetermined wavelength
optical
wavelength light
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Priority to US15/843,115 priority Critical patent/US10660523B2/en
Priority to CN201810057578.9A priority patent/CN109211784A/en
Priority to CN202211646296.5A priority patent/CN116413211A/en
Publication of JP2019015709A publication Critical patent/JP2019015709A/en
Priority to US16/852,902 priority patent/US10918284B2/en
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Priority to JP2022100732A priority patent/JP7332120B2/en
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発光源と光学特性変更部から構成される光源部において
前記発光源から放射された所定波長光が、前記光学特性変更部内の互いに異なる第1の光路または第2の光路を通過し、
前記光学特性変更部内では、前記第1の光路と前記第2の光路との間の光路長が変化し、
前記第1の光路を通過した前記所定波長と前記第2の光路を通過した前記所定波長光合成または混合する光源部。
In the light source unit consisting of the light emitting source and the optical characteristic changing unit ,
The predetermined wavelength light emitted from the light emitting source passes through a first optical path or a second optical path different from each other in the optical characteristic changing unit .
In the optical characteristic changing unit, the optical path length between the first optical path and the second optical path changes, and the optical path length changes.
It said first optical path the light source unit you combining or mixing the predetermined wavelength light having passed through the second optical path and the predetermined wavelength light that has passed through the.
対象体に照射する所定の波長光を含む第1の光を放射する光源部と、
前記対象体から得られる第2の光を検出する検出部と、から構成される測定装置において、
前記第1の光の光路の少なくとも一部は、第1の光路と第2の光路から構成され、
前記第1の光路と前記第2の光路との間の光路長が変化し、
前記第1の光路と前記第2の光路を個別に通過した前記所定の波長光は、所定箇所で合成または混合される測定装置。
A light source unit that emits first light including light of a predetermined wavelength that irradiates the object,
In a measuring device including a detection unit that detects a second light obtained from the object,
The first light at least a portion of the optical path of the is composed of a first optical path and second optical path,
The optical path length between the first optical path and the second optical path changes,
A measuring device in which the predetermined wavelength light that has passed through the first optical path and the second optical path individually is synthesized or mixed at a predetermined location.
所定の波長光を分割して、互いに異なる第1の光路内または第2の光路内を通過させ、Light of a predetermined wavelength is divided and passed through different first optical paths or second optical paths.
前記第1の光路と前記第2の光路間で光路長が変化し、The optical path length changes between the first optical path and the second optical path,
前記第1の光路を通過した前記所定の波長光と前記第2の光路を通過した前記所定の波長光を合成して合成光を生成し、The predetermined wavelength light that has passed through the first optical path and the predetermined wavelength light that has passed through the second optical path are combined to generate synthetic light.
生成した前記合成光を放出する合成光生成方法。A method for generating synthetic light that emits the generated synthetic light.
所定の波長光を含む第1の光を対象体に照射し、前記対象体から得られる第2の光を検出する光学的検出方法であり、
前記第1の光の光路の少なくとも一部は、互いに異なる第1の光路と第2の光路から構成され、
前記第1の光路と前記第2の光路との間の光路長が変化し、
前記第1の光路と前記第2の光路を個別に通過した前記所定の波長光は、所定箇所で合成または混合される光学的検出方法。
It is an optical detection method that irradiates a target body with a first light including a predetermined wavelength light and detects a second light obtained from the target body.
The first light at least a portion of the optical path of the is composed of different first optical path and second optical path,
The optical path length between the first optical path and the second optical path changes,
An optical detection method in which the predetermined wavelength light that has passed through the first optical path and the second optical path individually is synthesized or mixed at a predetermined location.
所定の波長光を含む第1の光を対象体に照射し、前記対象体から得られる第2の光を利用してイメージングするイメージング方法であり、
前記第1の光の光路の少なくとも一部は、互いに異なる第1の光路と第2の光路から構成され、
前記第1の光路と前記第2の光路との間の光路長が変化し、
前記第1の光路と前記第2の光路を個別に通過した前記所定の波長光は、所定箇所で合成または混合されるイメージング方法。
This is an imaging method in which a target body is irradiated with first light including light having a predetermined wavelength, and the second light obtained from the target body is used for imaging.
The first light at least a portion of the optical path of the is composed of different first optical path and second optical path,
The optical path length between the first optical path and the second optical path changes,
An imaging method in which the predetermined wavelength light that has passed through the first optical path and the second optical path individually is combined or mixed at a predetermined location.
複数光路生成用光学特性変更部と光合成部から構成される光学特性変更部であり、It is an optical characteristic changing part consisting of an optical characteristic changing part for generating multiple optical paths and a photosynthetic part.
前記複数光路生成用光学特性変更部内で所定の波長光が第1の光路と第2の光路に分割され、A predetermined wavelength light is divided into a first optical path and a second optical path in the optical property changing unit for generating a plurality of optical paths.
前記第1の光路と前記第2の光路との間で光路長が変化し、The optical path length changes between the first optical path and the second optical path,
前記第1の光路内を通過した前記所定の波長光と前記第2の光路内を通過した前記所定の波長光が前記光合成部内で合成される光学特性変更部。An optical characteristic changing unit in which the predetermined wavelength light that has passed through the first optical path and the predetermined wavelength light that has passed through the second optical path are combined in the photosynthesis unit.
前記合成において、前記第1の光路を通過後の前記所定の波長光の進行方向と前記第2の光路を通過後の前記所定の波長光の進行方向を一致させる請求項3に記載の合成光生成方法。The synthetic light according to claim 3, wherein in the synthesis, the traveling direction of the predetermined wavelength light after passing through the first optical path and the traveling direction of the predetermined wavelength light after passing through the second optical path are made to coincide with each other. Generation method. 前記合成または混合では、前記第1の光路を通過後の前記所定の波長光の進行方向と前記第2の光路を通過後の前記所定の波長光の進行方向を一致させる請求項4に記載の光学的検出方法。The fourth aspect of the present invention, wherein in the synthesis or mixing, the traveling direction of the predetermined wavelength light after passing through the first optical path and the traveling direction of the predetermined wavelength light after passing through the second optical path are matched. Optical detection method. 前記第1の光路内を通過して前記光合成部を経た後の前記所定の波長光の進行方向と、The traveling direction of the predetermined wavelength light after passing through the first optical path and passing through the photosynthetic unit, and
前記第2の光路内を通過して前記光合成部を経た後の前記所定の波長光の進行方向と、が一致する請求項6に記載の光学特性変更部。The optical characteristic changing unit according to claim 6, wherein the traveling direction of the predetermined wavelength light after passing through the second optical path and passing through the photosynthetic unit coincides with the traveling direction.
0.7μm以上で2.5μm以下の範囲内に含まれる所定波長光の吸収特性を有する機能性バイオ関連物質で有り、
前記機能性バイオ関連物質に第1の光を照射し、前記機能性バイオ関連物質から得られる第2の光を用いて前記機能性バイオ関連物質の構造または状態状態変化が検出可能であり、
前記第1の光の光路の少なくとも一部は互いに異なる第1の光路と第2の光路から構成され、
前記第1の光路と前記第2の光路との間の光路長が変化し、
前記第1の光路と前記第2の光路を個別に通過した前記所定波長光は、所定箇所で合成または混合される機能性バイオ関連物質。
It is a functional bio-related substance having absorption characteristics of light of a predetermined wavelength contained in the range of 0.7 μm or more and 2.5 μm or less .
The functional bio-related substance is irradiated with the first light, and the structure, state , or state change of the functional bio-related substance can be detected by using the second light obtained from the functional bio-related substance.
At least part of the optical path of the first light is composed of different first optical path and second optical path from each other,
The optical path length between the first optical path and the second optical path changes,
The predetermined wavelength light that has passed through the first optical path and the second optical path individually is a functional bio-related substance that is synthesized or mixed at a predetermined location.
JP2017235820A 2017-07-07 2017-12-08 Synthetic light generating method, optical property changing unit, light source unit, measuring device, optical detection method, imaging method Active JP7163019B2 (en)

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US15/843,115 US10660523B2 (en) 2017-07-07 2017-12-15 Light-source unit, measurement apparatus, near-infrared microscopic apparatus, optical detection method, imaging method, calculation method, functional bio-related substance, state management method, and manufacturing method
CN201810057578.9A CN109211784A (en) 2017-07-07 2018-01-19 Light source portion, measurement device, near-infrared microscope equipment, optical detecting method, functional living being hazardous substance and method of state management
CN202211646296.5A CN116413211A (en) 2017-07-07 2018-01-19 Light source unit, optical detection method and apparatus, imaging method and apparatus
US16/852,902 US10918284B2 (en) 2017-07-07 2020-04-20 Light-source unit, measurement apparatus, near-infrared microscopic apparatus, optical detection method, imaging method, calculation method, functional bio-related substance, state management method, and manufacturing method
JP2022100732A JP7332120B2 (en) 2017-07-07 2022-06-22 Synthetic light generating method, optical property changing unit, light source unit, measuring device, optical detection method, imaging method
JP2023125423A JP2023153925A (en) 2017-07-07 2023-08-01 Method for generating synthetic light, method for using light, light source unit, imaging method, and optical detection method

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