JP2018535236A5 - - Google Patents

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JP2018535236A5
JP2018535236A5 JP2018527219A JP2018527219A JP2018535236A5 JP 2018535236 A5 JP2018535236 A5 JP 2018535236A5 JP 2018527219 A JP2018527219 A JP 2018527219A JP 2018527219 A JP2018527219 A JP 2018527219A JP 2018535236 A5 JP2018535236 A5 JP 2018535236A5
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Japan
Prior art keywords
powder
fine needle
water
needle
spicule
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JP2018527219A
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Japanese (ja)
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JP2018535236A (en
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Priority claimed from PCT/KR2016/013634 external-priority patent/WO2017091010A1/en
Priority claimed from KR1020160157312A external-priority patent/KR20170061082A/en
Publication of JP2018535236A publication Critical patent/JP2018535236A/en
Publication of JP2018535236A5 publication Critical patent/JP2018535236A5/ja
Priority to JP2021110833A priority Critical patent/JP7233120B2/en
Pending legal-status Critical Current

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Claims (18)

三角錐（ｔｒｉａｎｇｕｌａｒ ｐｙｒａｍｉｄ）ないし六角錐（ｓｅｘａｎｇｕｌａｒ ｐｙｒａｍｉｄ）形状の水溶性微細ニードル粉末であって、錐底面の内角のうち少なくともいずれか１つが９０度以下である、水溶性微細ニードル（ｍｉｃｒｏ−ｎｅｅｄｌｅ）粉末（ｓｐｉｃｕｌｅ）。 A triangular pyramid (triangular pyramid) to hexagonal pyramid (sexangular pyramid) water-soluble fine needle powder shape, one even without least Chi caries internal angle of the cone bottom is 90 degrees or less, the water-soluble fine needle (micro -Needle) a powder. 前記微細ニードル粉末が、多糖類、単糖類、オリゴ糖類、ポリビニルアルコール、カルボキシビニル重合体、セルロース重合体、ヒアルロン酸重合体、及びキトサンからなる群より選ばれるいずれか１つ以上またはそれらの混合物を有する、請求項１に記載の水溶性微細ニードル（ｍｉｃｒｏ−ｎｅｅｄｌｅ）粉末（ｓｐｉｃｕｌｅ）。 The fine needle powder, polysaccharide, monosaccharides, oligosaccharides, polyvinyl alcohol, carboxyvinyl polymers, cellulose polymers, hyaluronic acid polymers, and chitosan down or Ranaru from any one or more or their selected group having mixtures, water-soluble fine needle according to claim 1 (micro-needle) powder (spicule). 前記微細ニードル粉末がヒアルロン酸重合体を有する、請求項１に記載の水溶性微細ニードル（ｍｉｃｒｏ−ｎｅｅｄｌｅ）粉末（ｓｐｉｃｕｌｅ）。 The fine needle powder has a hyaluronic acid polymer, water-soluble fine needle according to claim 1 (micro-needle) powder (spicule). 前記ヒアルロン酸重合体の分子量が０．１ｋＤａないし５０ｋＤａである、請求項３に記載の水溶性微細ニードル（ｍｉｃｒｏ−ｎｅｅｄｌｅ）粉末（ｓｐｉｃｕｌｅ）。 The molecular weight of the hyaluronic acid polymer are 50kDa to no 0.1 kDa, water-soluble fine needle according to 請 Motomeko 3 (micro-needle) powder (spicule). 前記微細ニードル粉末のサイズが０．０１ｍｍないし２ｍｍである、請求項１に記載の水溶性微細ニードル（ｍｉｃｒｏ−ｎｅｅｄｌｅ）粉末（ｓｐｉｃｕｌｅ）。 Said to have no 0.01mm size of the fine needle powder is 2 mm, water-soluble fine needle according to claim 1 (micro-needle) powder (spicule). 前記微細ニードル粉末の頂点内角が４０度以下である、請求項１に記載の水溶性微細ニードル（ｍｉｃｒｏ−ｎｅｅｄｌｅ）粉末（ｓｐｉｃｕｌｅ）。 The apex interior angle of the fine needle powder Ru der 40 degrees or less, the water-soluble fine needle according to claim 1 (micro-needle) powder (spicule). 前記微細ニードル粉末の内部が空いている、請求項１に記載の水溶性微細ニードル（ｍｉｃｒｏ−ｎｅｅｄｌｅ）粉末（ｓｐｉｃｕｌｅ）。 The interior of the fine needle powder is free, water-soluble fine needle according to claim 1 (micro-needle) powder (spicule). 前記微細ニードル粉末は、生理活性有効成分を含有する、請求項１に記載の水溶性微細ニードル（ｍｉｃｒｏ−ｎｅｅｄｌｅ）粉末（ｓｐｉｃｕｌｅ）。 The water-soluble micro-needle powder according to claim 1, wherein the fine needle powder contains a biologically active ingredient. 前記微細ニードル粉末がヒアルロン酸重合体を有する、請求項８に記載の水溶性微細ニードル（ｍｉｃｒｏｎｅｅｄｌｅ）粉末（ｓｐｉｃｕｌｅ）。 The fine needle powder has a hyaluronic acid polymer, water-soluble fine needle according to claim 8 (microneedle) powder (spicule). 前記ヒアルロン酸重合体の分子量が０．１ｋＤａないし５０ｋＤａである、請求項９に記載の水溶性微細ニードル（ｍｉｃｒｏｎｅｅｄｌｅ）粉末（ｓｐｉｃｕｌｅ）。 The molecular weight of the hyaluronic acid polymer are 50kDa to no 0.1 kDa, water-soluble fine needle according to claim 9 (microneedle) powder (spicule). 前記微細ニードル粉末の内部が空いている、請求項８に記載の水溶性微細ニードル（ｍｉｃｒｏｎｅｅｄｌｅ）粉末（ｓｐｉｃｕｌｅ）。 The fine needle inside the powder is free, water-soluble fine needle according to 請 Motomeko 8 (microneedle) powder (spicule). 前記生理活性有効成分が、ポリペプチド、オリゴペプチド、細胞培養濾液、ＤＮＡ断片、ＲＮＡ断片、抗酸化剤、インシュリン、及び成長ホルモンからなる群より選ばれるいずれか１つ以上またはそれらの混合物である、請求項８に記載の水溶性微細ニードル（ｍｉｃｒｏｎｅｅｄｌｅ）粉末（ｓｐｉｃｕｌｅ）。 The bioactive active ingredient, a polypeptide, an oligopeptide, a cell culture filtrate, DNA fragments, RNA fragments, antioxidants, insulin, and any one or more or a mixture thereof selected from the group consisting of growth hormone there, the water-soluble fine needle (microneedle) powder according to 請 Motomeko 8 (spicule). 前記生理活性有効成分が、ヒト上皮成長因子（ＥＧＦ）、繊維芽細胞成長因子（ＦＧＦ）、幹細胞培養濾液及びビタミンＣの群から選ばれる１つ以上又はこれらの混合物である、請求項８に記載の水溶性微細ニードル（ｍｉｃｒｏｎｅｅｄｌｅ）粉末（ｓｐｉｃｕｌｅ）。 The bioactive active ingredient, human epidermal growth factor (EGF), fibroblast growth factor (FGF), is one or more or a mixture thereof selected from the group consisting of stem cell culture filtrate and vitamin C, the 請 Motomeko 8 water-soluble fine needle according (microneedle) powder (spicule). 三角錐（ｔｒｉａｎｇｕｌａｒ ｐｙｒａｍｉｄ）ないし六角錐（ｓｅｘａｎｇｕｌａｒ ｐｙｒａｍｉｄ）形状の水溶性微細ニードル粉末であって、錐底面の内角のうち少なくともいずれか１つが９０度以下である水溶性微細ニードル（ｍｉｃｒｏ−ｎｅｅｄｌｅ）粉末（ｓｐｉｃｕｌｅ）を含有する、非水系化粧剤組成物。 Triangular pyramid (triangular pyramid) to hexagonal pyramid (sexangular pyramid) a water-soluble fine needle powder form, water-soluble fine needle one even without least Chi caries internal angle of the cone bottom is 90 degrees or less (micro- needle) containing a powder (spicule), non-aqueous cosmetic composition. 前記水溶性微細ニードル粉末が化粧剤組成物重量に対して０．０１重量％ないし１５重量％である、請求項１４に記載の非水系化粧剤組成物。 The water-soluble fine needle powder is 0.01% to 15% by weight relative to the cosmetic composition weight, non-aqueous cosmetic composition according to claim 14. 前記水溶性微細ニードル粉末は、生理活性有効成分を含有する、請求項１４に記載の非水系化粧剤組成物。 The non-aqueous cosmetic composition according to claim 14, wherein the water-soluble fine needle powder contains a physiologically active ingredient. 三角錐（ｔｒｉａｎｇｕｌａｒ ｐｙｒａｍｉｄ）ないし六角錐（ｓｅｘａｎｇｕｌａｒ ｐｙｒａｍｉｄ）形状の水溶性微細ニードル粉末であって、錐底面の内角のうち少なくともいずれか１つが９０度以下である第１の水溶性微細ニードル（ｍｉｃｒｏ−ｎｅｅｄｌｅ）粉末（ｓｐｉｃｕｌｅ）と；
三角錐（ｔｒｉａｎｇｕｌａｒ ｐｙｒａｍｉｄ）ないし六角錐（ｓｅｘａｎｇｕｌａｒ ｐｙｒａｍｉｄ）形状の水溶性微細ニードル粉末であって、錐底面の内角のうち少なくともいずれか１つが９０度以下であり、生理活性有効成分を含有する第２の水溶性微細ニードル（ｍｉｃｒｏ−ｎｅｅｄｌｅ）粉末（ｓｐｉｃｕｌｅ）と；
を含有する、非水系化粧剤組成物。 A triangular pyramid (triangular pyramid) to hexagonal pyramid (sexangular pyramid) water-soluble fine needle powder form, the first water-soluble fine needle any one even without least Chi caries internal angle of the cone bottom is less than 90 degrees (Micro-needle) powder ;
A triangular pyramid (triangular pyramid) to hexagonal pyramid (sexangular pyramid) water-soluble fine needle powder shape, one even without least Chi caries internal angle of the cone bottom but not more than 90 degrees, containing a physiologically active active ingredient A second water-soluble micro-needle powder ;
The having-containing, non-aqueous cosmetic composition. 前記生理活性有効成分が、ヒト上皮成長因子（ＥＧＦ）、繊維芽細胞成長因子（ＦＧＦ）、幹細胞培養濾液及びビタミンＣの群から選ばれる１つ以上又はこれらの混合物である、請求項１７に記載の非水系化粧剤組成物。 The biologically active effective ingredients, human epidermal growth factor (EGF), fibroblast growth factor (FGF), is one or more or a mixture thereof selected from the group consisting of stem cell culture filtrate and vitamin C, 請 Motomeko 17 3. The non- aqueous cosmetic composition according to item 1.
JP2018527219A 2015-11-25 2016-11-24 Water-soluble fine needle powder and non-aqueous cosmetic composition containing the same Pending JP2018535236A (en)

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KR20150165847 2015-11-25
KR10-2015-0165847 2015-11-25
PCT/KR2016/013634 WO2017091010A1 (en) 2015-11-25 2016-11-24 Water-soluble microneedle spicules and nonaqueous cosmetic composition containing same
KR1020160157312A KR20170061082A (en) 2015-11-25 2016-11-24 Water-Soluble Micro-Spicules and Non-Aqueous Cosmetic Composition Comprising the Same
KR10-2016-0157312 2016-11-24

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