JP2018530622A5 - - Google Patents
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- Publication number
- JP2018530622A5 JP2018530622A5 JP2018539225A JP2018539225A JP2018530622A5 JP 2018530622 A5 JP2018530622 A5 JP 2018530622A5 JP 2018539225 A JP2018539225 A JP 2018539225A JP 2018539225 A JP2018539225 A JP 2018539225A JP 2018530622 A5 JP2018530622 A5 JP 2018530622A5
- Authority
- JP
- Japan
- Prior art keywords
- gel formulation
- composition
- gel
- urinary tract
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000203 mixture Substances 0.000 claims description 21
- 238000009472 formulation Methods 0.000 claims description 17
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims description 12
- 208000019206 urinary tract infection Diseases 0.000 claims description 11
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims description 9
- 239000013022 formulation composition Substances 0.000 claims description 8
- 244000000010 microbial pathogen Species 0.000 claims description 8
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims description 6
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 claims description 6
- 150000001875 compounds Chemical class 0.000 claims description 6
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 claims description 6
- 235000015112 vegetable and seed oil Nutrition 0.000 claims description 6
- 239000008158 vegetable oil Substances 0.000 claims description 6
- 229920000663 Hydroxyethyl cellulose Polymers 0.000 claims description 4
- 239000004354 Hydroxyethyl cellulose Substances 0.000 claims description 4
- 239000004264 Petrolatum Substances 0.000 claims description 4
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims description 4
- 235000019447 hydroxyethyl cellulose Nutrition 0.000 claims description 4
- 235000019271 petrolatum Nutrition 0.000 claims description 4
- 229940066842 petrolatum Drugs 0.000 claims description 4
- 239000011780 sodium chloride Substances 0.000 claims description 4
- 229940100613 topical solution Drugs 0.000 claims description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 4
- 229920002153 Hydroxypropyl cellulose Polymers 0.000 claims description 3
- 239000003242 anti bacterial agent Substances 0.000 claims description 3
- 239000003429 antifungal agent Substances 0.000 claims description 3
- 229940121375 antifungal agent Drugs 0.000 claims description 3
- 239000003904 antiprotozoal agent Substances 0.000 claims description 3
- 239000003443 antiviral agent Substances 0.000 claims description 3
- 235000010323 ascorbic acid Nutrition 0.000 claims description 3
- 229960005070 ascorbic acid Drugs 0.000 claims description 3
- 239000011668 ascorbic acid Substances 0.000 claims description 3
- UWLPCYBIJSLGQO-UHFFFAOYSA-N dodecanoic acid;propane-1,2,3-triol Chemical compound OCC(O)CO.CCCCCCCCCCCC(O)=O UWLPCYBIJSLGQO-UHFFFAOYSA-N 0.000 claims description 3
- 239000001863 hydroxypropyl cellulose Substances 0.000 claims description 3
- 235000010977 hydroxypropyl cellulose Nutrition 0.000 claims description 3
- 235000014655 lactic acid Nutrition 0.000 claims description 3
- 239000004310 lactic acid Substances 0.000 claims description 3
- 229940068918 polyethylene glycol 400 Drugs 0.000 claims description 3
- 230000003115 biocidal effect Effects 0.000 claims description 2
- 230000002401 inhibitory effect Effects 0.000 claims description 2
- 230000000699 topical effect Effects 0.000 claims description 2
- ARIWANIATODDMH-AWEZNQCLSA-N 1-lauroyl-sn-glycerol Chemical compound CCCCCCCCCCCC(=O)OC[C@@H](O)CO ARIWANIATODDMH-AWEZNQCLSA-N 0.000 claims 1
- ARIWANIATODDMH-UHFFFAOYSA-N Lauric acid monoglyceride Natural products CCCCCCCCCCCC(=O)OCC(O)CO ARIWANIATODDMH-UHFFFAOYSA-N 0.000 claims 1
- 239000007788 liquid Substances 0.000 claims 1
- 238000000034 method Methods 0.000 description 13
- 235000019482 Palm oil Nutrition 0.000 description 3
- 235000005687 corn oil Nutrition 0.000 description 3
- 239000002285 corn oil Substances 0.000 description 3
- 239000004006 olive oil Substances 0.000 description 3
- 235000008390 olive oil Nutrition 0.000 description 3
- 239000002540 palm oil Substances 0.000 description 3
- 230000002485 urinary effect Effects 0.000 description 2
- WZIMSXIXZTUBSO-UHFFFAOYSA-N 2-[[bis(carboxymethyl)amino]methyl-(carboxymethyl)amino]acetic acid Chemical compound OC(=O)CN(CC(O)=O)CN(CC(O)=O)CC(O)=O WZIMSXIXZTUBSO-UHFFFAOYSA-N 0.000 description 1
- 239000002202 Polyethylene glycol Substances 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 229920002678 cellulose Polymers 0.000 description 1
- 239000001913 cellulose Substances 0.000 description 1
- 239000002738 chelating agent Substances 0.000 description 1
- 235000015165 citric acid Nutrition 0.000 description 1
- 150000002334 glycols Chemical class 0.000 description 1
- 150000004678 hydrides Chemical class 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 229920001223 polyethylene glycol Polymers 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562241321P | 2015-10-14 | 2015-10-14 | |
| US62/241,321 | 2015-10-14 | ||
| PCT/US2016/056078 WO2017066100A1 (en) | 2015-10-14 | 2016-10-07 | Compositions and methods to treat urinary tract infections |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2018530622A JP2018530622A (ja) | 2018-10-18 |
| JP2018530622A5 true JP2018530622A5 (enExample) | 2019-11-14 |
Family
ID=58518539
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018539225A Pending JP2018530622A (ja) | 2015-10-14 | 2016-10-07 | 尿路感染症を治療するための組成物および方法 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20180289656A1 (enExample) |
| EP (1) | EP3362062A4 (enExample) |
| JP (1) | JP2018530622A (enExample) |
| AU (1) | AU2016338662A1 (enExample) |
| BR (1) | BR112018007359A2 (enExample) |
| CA (1) | CA3000213A1 (enExample) |
| IL (1) | IL258683A (enExample) |
| WO (1) | WO2017066100A1 (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20190022227A1 (en) * | 2017-05-03 | 2019-01-24 | Regents Of The University Of Minnesota | Topical composition comprising glycerol monolaurate |
| IL316407A (en) * | 2022-04-19 | 2024-12-01 | Watershed Medical Inc | A preparation for the treatment of urinary system disorders |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4067997A (en) * | 1975-05-21 | 1978-01-10 | Med-Chem Laboratories | Synergistic microbecidal composition and method |
| US20050058673A1 (en) * | 2003-09-09 | 2005-03-17 | 3M Innovative Properties Company | Antimicrobial compositions and methods |
| EP4241844A3 (en) * | 2012-04-20 | 2023-11-08 | Hennepin Life Sciences | Compositions for topical treatment of microbial infections |
| WO2014051689A1 (en) * | 2012-09-25 | 2014-04-03 | University Of Iowa Research Foundation | Antimicrobial compositions and methods of use thereof |
-
2016
- 2016-10-07 CA CA3000213A patent/CA3000213A1/en not_active Abandoned
- 2016-10-07 EP EP16855992.0A patent/EP3362062A4/en not_active Withdrawn
- 2016-10-07 BR BR112018007359A patent/BR112018007359A2/pt not_active Application Discontinuation
- 2016-10-07 WO PCT/US2016/056078 patent/WO2017066100A1/en not_active Ceased
- 2016-10-07 AU AU2016338662A patent/AU2016338662A1/en not_active Abandoned
- 2016-10-07 US US15/765,816 patent/US20180289656A1/en not_active Abandoned
- 2016-10-07 JP JP2018539225A patent/JP2018530622A/ja active Pending
-
2018
- 2018-04-12 IL IL258683A patent/IL258683A/en unknown
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