JP2018509426A5 - - Google Patents

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Publication number
JP2018509426A5
JP2018509426A5 JP2017548389A JP2017548389A JP2018509426A5 JP 2018509426 A5 JP2018509426 A5 JP 2018509426A5 JP 2017548389 A JP2017548389 A JP 2017548389A JP 2017548389 A JP2017548389 A JP 2017548389A JP 2018509426 A5 JP2018509426 A5 JP 2018509426A5
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JP
Japan
Prior art keywords
compound
treatment
prevention
solvate
salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2017548389A
Other languages
English (en)
Japanese (ja)
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JP2018509426A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2016/055496 external-priority patent/WO2016146606A1/de
Publication of JP2018509426A publication Critical patent/JP2018509426A/ja
Publication of JP2018509426A5 publication Critical patent/JP2018509426A5/ja
Pending legal-status Critical Current

Links

JP2017548389A 2015-03-19 2016-03-15 血栓症の治療のための因子XIa阻害剤としてのオキソピリジン誘導体 Pending JP2018509426A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP15159829.9 2015-03-19
EP15159829 2015-03-19
PCT/EP2016/055496 WO2016146606A1 (de) 2015-03-19 2016-03-15 Oxopyridin-derivate als faktor xia hemmer zur behandlung von thrombose

Publications (2)

Publication Number Publication Date
JP2018509426A JP2018509426A (ja) 2018-04-05
JP2018509426A5 true JP2018509426A5 (US20070167479A1-20070719-C00034.png) 2019-04-11

Family

ID=52736868

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2017548389A Pending JP2018509426A (ja) 2015-03-19 2016-03-15 血栓症の治療のための因子XIa阻害剤としてのオキソピリジン誘導体

Country Status (7)

Country Link
US (1) US20190119213A1 (US20070167479A1-20070719-C00034.png)
EP (1) EP3271332A1 (US20070167479A1-20070719-C00034.png)
JP (1) JP2018509426A (US20070167479A1-20070719-C00034.png)
CN (1) CN107428689A (US20070167479A1-20070719-C00034.png)
CA (1) CA2979937A1 (US20070167479A1-20070719-C00034.png)
HK (1) HK1247615A1 (US20070167479A1-20070719-C00034.png)
WO (1) WO2016146606A1 (US20070167479A1-20070719-C00034.png)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10077265B2 (en) * 2014-09-24 2018-09-18 Bayer Pharma Aktiengesellschaft Substituted oxopyridine derivatives
US11884660B2 (en) 2018-04-10 2024-01-30 Bayer Pharma Aktiengesellschaft Substituted oxopyridine derivative
BR112021000439A2 (pt) * 2018-07-19 2021-04-06 Jiangsu Hengrui Medicine Co., Ltd. Método para preparar o inibidor do fator de coagulação xia e intermediário do mesmo
TW202039510A (zh) * 2018-12-21 2020-11-01 德商拜耳廠股份有限公司 經取代的側氧基吡啶衍生物
CA3124296A1 (en) 2018-12-21 2020-06-25 Bayer Aktiengesellschaft Substituted oxopyridine derivatives
CN116947818B (zh) * 2023-09-18 2023-12-19 成都施贝康生物医药科技有限公司 一种氧代吡啶类化合物、中间体及其制备方法和用途

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200813017A (en) * 2006-05-05 2008-03-16 Millennium Pharm Inc Factor XA inhibitors
WO2014160592A2 (en) * 2013-03-27 2014-10-02 Merck Sharp & Dohme Corp. FACTOR XIa INHIBITORS
TWI633089B (zh) * 2013-03-28 2018-08-21 拜耳製藥股份有限公司 經取代的酮基吡啶衍生物
EP3063150B1 (de) * 2013-10-30 2017-11-22 Bayer Pharma Aktiengesellschaft Substituierte oxopyridin-derivate
WO2016046156A1 (de) * 2014-09-24 2016-03-31 Bayer Pharma Aktiengesellschaft Substituierte oxopyridin-derivate
JP6517925B2 (ja) * 2014-09-24 2019-05-22 バイエル ファーマ アクチエンゲゼルシャフト 置換されたオキソピリジン誘導体
US10077265B2 (en) * 2014-09-24 2018-09-18 Bayer Pharma Aktiengesellschaft Substituted oxopyridine derivatives
US10138236B2 (en) * 2014-09-24 2018-11-27 Bayer Pharma Aktiengesellschaft Factor xia-inhibiting pyridobenzazepine and pyridobenzazocine derivatives
WO2016046159A1 (de) * 2014-09-24 2016-03-31 Bayer Pharma Aktiengesellschaft Substituierte oxopyridin-derivate
EP3197872B1 (de) * 2014-09-24 2019-01-30 Bayer Pharma Aktiengesellschaft (2h)-2-oxopyridine als faktor xia-inhibitoren zur behandlung von thrombotischen erkrankungen
JO3703B1 (ar) * 2015-07-09 2021-01-31 Bayer Pharma AG مشتقات أوكسوبيريدين مستبدلة
WO2017037051A1 (de) * 2015-09-04 2017-03-09 Bayer Pharma Aktiengesellschaft Substituierte oxopyridin-derivate
RU2742771C2 (ru) * 2016-08-31 2021-02-10 Цзянсу Хэнжуй Медицин Ко., Лтд. Производное оксопиколинамида, способ его получения и его фармацевтическое применение

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