JP2018201694A - Biological sensor and measuring method using biological sensor - Google Patents

Abstract

To provide a biological sensor that can be comfortably worn and can detect a weak biological signal in a stable manner, and a measuring method using the biological sensor.SOLUTION: A biological sensor 100a includes a belt-like base material 1 having at least one of flexibility and elasticity, which can be wound around the whole circumference or longer of a predetermined site of a living body, at least one detection electrode 2 provided on a principal surface of a living body side of the base material 1 for detecting a biological signal of the living body, and at least one ground electrode 3 provided at a position different from the position of the detection electrode 2 on the principal surface of the living body side of the base material 1. The ground electrode 3 is provided on the base material 1 so that the ground electrode 3 covers the detection electrode 2 when the base material 1 is wound around the whole circumference or longer of the predetermined site of the living body.SELECTED DRAWING: Figure 1B

Description

  The present disclosure relates to a biosensor and a biosignal measurement method using the biosensor.

  Since biological information such as an electrocardiogram, an electroencephalogram, and an electromyogram is very weak, it is important for biological information sensing to remove the influence of external noise and body movement. For example, in Patent Document 1, myoelectric potential measurement electrodes are arranged on the inner surface of a conductive sheet, that is, the surface in contact with the human body, and the conductive sheet goes around the human body and measures the myoelectric potential in a cylindrical shape. Disclosed is a myoelectric potential measurement device that covers a medical electrode.

  There is also a need for a biosensor that anyone can easily wear and that can be used repeatedly. For example, Patent Document 2 discloses a surface myoelectric potential sensor in which a myoelectric potential detection electrode and an amplifier circuit are connected by a coaxial cable, and the outer conductor of the coaxial cable is a body ground wiring.

JP 2011-000223 A JP 2010-264174 A

  The present disclosure provides a biosensor that is comfortable to wear and can stably detect a weak biosignal, and a measurement method using the biosensor.

  A biosensor according to one embodiment of the present disclosure has at least one of flexibility and stretchability, a belt-like base substrate that can be wound around the entire circumference of a predetermined part of the living body, and the living body side of the base substrate And at least one detection electrode for detecting a biological signal of a living body, and at least one ground electrode provided at a position different from the detection electrode on the main surface of the base substrate on the living body side, The ground electrode is provided on the base substrate so that the ground electrode covers the detection electrode when the base substrate is wound around the entire circumference of the predetermined part of the living body.

  In addition, a measurement method using the biosensor according to one embodiment of the present disclosure includes a belt-like base substrate that has at least one of flexibility and stretchability and can be wound around the entire circumference of a predetermined part of a living body. The at least one detection electrode that is provided on the main surface of the base substrate on the living body side and detects a biological signal of the living body and the detection electrode on the main surface of the base substrate on the living body side are provided at different positions. A biosensor comprising at least one ground electrode, and the biosensor is wound so that the ground electrode covers the detection electrode when wound around the entire circumference of a predetermined part of the living body, and is detected by the detection electrode Measure the vital signal.

  According to the present disclosure, there are provided a biosensor that is comfortable to wear and can stably detect a weak biosignal and a measurement method using the biosensor.

1A is a perspective view schematically showing a biosensor according to Embodiment 1. FIG. FIG. 1B is a perspective view schematically showing how the biosensor according to Embodiment 1 is attached to a living body. 1C is a schematic cross-sectional view taken along line IC-IC in FIG. 1B. FIG. 1D is an enlarged view of a part of the schematic cross-sectional view of FIG. 1C when the biosensor according to Embodiment 1 is attached to a living body. FIG. 2 is a diagram for explaining an example of use of the biosensor according to the first embodiment. FIG. 3 is a perspective view schematically showing a biosensor according to the second embodiment. FIG. 4 is a diagram for explaining an example of use of the biosensor according to the second embodiment. FIG. 5A is a plan view schematically showing a biosensor according to Embodiment 3. FIG. 5B is a schematic cross-sectional view taken along line VB-VB in FIG. 5A. FIG. 5C is a diagram of the detection unit viewed from the living body side when the biosensor according to Embodiment 3 is attached to the living body. 5D is a schematic cross-sectional view taken along line VD-VD in FIG. 5C. FIG. 5E is a schematic cross-sectional view taken along the line VD-VD when the signal processing circuit unit is attached to the biosensor according to Embodiment 3. FIG. 6A is a plan view schematically showing a biosensor according to Embodiment 4. FIG. 6B is a schematic cross-sectional view taken along line VIB-VIB in FIG. 6A. FIG. 6C is a diagram of the detection unit viewed from the living body side when the living body sensor according to Embodiment 4 is attached to the living body. 6D is a schematic cross-sectional view taken along line VID-VID in FIG. 6C. FIG. 7A is a plan view schematically showing a biosensor according to Embodiment 5. FIG. 7B is a schematic cross-sectional view taken along the line VIIB-VIIB in FIG. 7A when the biological sensor in FIG. 7A is wound around the living body.

(Knowledge that led to this disclosure)
2. Description of the Related Art Conventionally, biomedical sensors that acquire vital information on living bodies such as electrocardiograms, electroencephalograms, and myoelectrics have been used for diagnosis of diseases and health conditions in medical practice. However, the biosensor is systemized as a medical device and cannot be used for daily monitoring.

  However, in recent years, biosensors have been increasingly mounted on wearable devices, and vital information can be acquired by attaching the wearable device to the body even during daily activities. Along with this, new needs such as applications for monitoring activities in daily health care, fitness and sports, powered suits equipped with actuators, HMI (Human Machine Interface) on prosthetic hands or prosthetic legs, etc. Service proposals for the needs of people are being made.

  In the configuration described in Patent Document 1 described above, the electroconductive sheet and the myoelectric potential measurement electrode are not arranged on the same plane, and the myoelectric potential measurement is performed on the inner side of the electroconductive sheet, that is, on the surface in contact with the human body. An electrode is disposed. Therefore, a plurality of insulating layers must be interposed between the conductive sheet and the myoelectric potential measuring electrode. Furthermore, a configuration is required in which wiring is routed from the myoelectric potential measurement electrode to the outside of the conductive sheet, that is, the side opposite to the side in contact with the human body. In order to route the wiring from the myoelectric potential measurement electrode to the outside of the conductive sheet, an insulating layer, a through hole, a connection wiring, and the like are required, and the layer configuration is complicated. As a result, even if the electroconductive sheet has flexibility and stretchability, the myoelectric potential measurement device cannot secure the flexibility and stretchability of the entire device, and the followability to the expansion and contraction and body movement of the living body is poor. Become. For this reason, there is a problem that not only the flexibility and comfort are impaired, but also noise due to the displacement between the living body surface and the electrode due to body movement is generated, and the connection reliability at the time of expansion and contraction is deteriorated. In addition, since the conductive sheet has a through-hole extending from the myoelectric potential measurement electrode to the outside of the conductive sheet, it is difficult to completely eliminate the influence of external noise on the myoelectric potential measurement electrode.

  From the above viewpoint, the present inventors have intensively studied and came up with the biosensor of the present disclosure. This knowledge will be described below.

  Biological vital information such as electroencephalogram, electrocardiogram, and myoelectricity is very weak. Therefore, it is necessary to remove as much as possible the noise source generated in the process of detecting the biological signal from the biological electrode. In particular, wearable biosensing devices such as wear-type biosensors can be easily detached and attached, have less tightness and do not impair comfort, unlike stationary medical devices such as conventional biosensors. A simple configuration is required. Furthermore, a wearable biological sensing device needs to realize a highly accurate biological sensor with a simple configuration. As described above, in consideration of convenience, the priority is given to the attachment / detachment and the simplification of the configuration, and it becomes more difficult to take measures for reducing the influence of external noise such as electromagnetic noise.

  In addition, in order to detect a weak biological signal, it is extremely important to remove external noise such as hum noise. For this reason, conventionally, as a method for removing extraneous noise, a living body grounding method has been performed in which an electrode for grounding a living body as a reference potential (GND) of a circuit is prepared separately from a detection electrode. However, with this method alone, it is difficult to completely remove external noise. In particular, in a simple structure such as a wear type, the influence of external noise can be easily cut off for the entire device including the detection electrodes and wiring. A structure is needed.

  In addition, noise that may be caused by wearing a wearable biological sensing device, for example, noise generated by displacement of the biological surface due to expansion and contraction of the biological surface and body movement (hereinafter referred to as “electrode noise”), and biological The influence of noise such as static electricity caused by rubbing between the device and the clothes cannot be ignored. In particular, when a dry electrode is used for a wear-type biosensor with an emphasis on comfort (hereinafter referred to as “dry method”), there is a problem in the adhesion between the surface of the living body and the electrode. In addition, due to body movement, the influence of electrode noise due to displacement between the surface of the living body and the electrode and poor adhesion appears significantly.

  Conventionally, in order to stably acquire the potential of a living body, a so-called wet electrode in the form of a pad soaked with a conductive gel is used as the living body electrode (hereinafter referred to as “wet method”). The electrical connection with the surface was ensured. However, the wet method is a method in which a wet electrode is directly attached to the surface of a living body and an electrical connection with the surface of the living body is established with a conductive gel or the like immersed in the electrode. It feels bad when you touch the surface directly. Further, when the wet electrode is brought into contact with the surface of the living body for a long time, troubles such as rough skin or rash occur.

  In the wet method, in activities involving sweating such as sports, sweat accumulates around the electrode, and the gel agent swells or flows out. Therefore, not only the wearing feeling is deteriorated, but also the detection sensitivity of the biological signal is reduced due to the peeling of the electrode component or the decrease in the adhesion between the electrode and the biological surface.

  From the above, it is difficult to say that the wet method is suitable for long-time wearing. Unlike medical applications that prioritize stable measurement, when general consumers wear wearable biological sensing devices on a daily basis, there is a lack of comfort and skin problems such as tightness when wearing them. Therefore, it is an important problem that long-time measurement is difficult.

  On the other hand, in the dry method using conductive fibers or the like as a dry electrode, skin troubles are improved, but it is difficult to ensure an electrical connection between the living body surface and the electrode by being in close contact with the living body surface. Therefore, for example, in a sports wear type biological sensor in which a wear and a sensor are integrated, by using a so-called compression wear, which has a binding force, the binding force especially in a portion where a dry electrode is arranged is increased. Adhesion between the electrode and the surface of the living body is performed. In the case of such a wear-type biosensor, in order to secure a close contact between the electrode and the living body surface and to stably acquire a living body signal, the pressure at which the wear tightens the living body surface, that is, between the wear and the living body surface. The contact pressure should be as large as possible. However, in this case, since it is necessary to increase the pressure of the entire wear, there is a demerit that a user feels a sense of restraint and uncomfortable feeling and impairs comfort. Along with this, there are also disadvantages such as difficulty in moving the body or significant friction between the body surface and the wear. In addition, since the wear and the sensor are integrated, the entire wear moves following the expansion and contraction of the place where the body movement is intense, and therefore, the wear and the sensor are easily affected by the deviation between the surface of the living body and the electrode and insufficient adhesion.

  From the above, in examining the structure to detect weak biological signals with high sensitivity in wear-type biosensors, it is easy to ensure desorption and comfort with a simple configuration, and at the same time, external noise such as electromagnetic noise, and It is important to remove electrode noise due to the expansion and contraction of the living body surface and body movement.

  As a result of intensive studies to solve the above problems, the present inventors have found a biosensor of the present disclosure. As will be described below, the biosensor of the present disclosure has a simple configuration and can remove external noise only by being wound around a predetermined part of a living body. In addition, the elasticity of the entire device can be maintained due to the simple configuration. Therefore, the biosensor of the present disclosure can have a shape and expansion / contraction of the surface of the living body and followability to body movement. Thereby, since the electrical connection between the living body surface and the detection electrode can be stably secured, electrode noise can be removed. Further, the biosensor of the present disclosure has been found to be capable of detecting a weak biosignal stably and with high sensitivity without impairing comfort by having the following ability.

  The present disclosure provides a biosensor that is comfortable to wear and can stably detect a weak biosignal, and a measurement method using the biosensor.

  A biosensor according to one embodiment of the present disclosure has at least one of flexibility and stretchability, a belt-like base substrate that can be wound around the entire circumference of a predetermined part of the living body, and the living body side of the base substrate And at least one detection electrode for detecting a biological signal of a living body, and at least one ground electrode provided at a position different from the detection electrode on the main surface of the base substrate on the living body side, The ground electrode is provided on the base substrate so that the ground electrode covers the detection electrode when the base substrate is wound around the entire circumference of the predetermined part of the living body.

  Thereby, since the ground electrode covers the detection electrode, the biological sensor can reduce the influence of external noise when detecting a weak signal from the biological surface. Therefore, the biological sensor can stably detect a weak biological signal. In addition, since the detection electrode and the ground electrode are provided on the same surface, the biosensor does not have a complicated multilayer structure. For this reason, the biosensor does not lose flexibility and is comfortable to wear.

  For example, the biosensor according to one embodiment of the present disclosure may include a wiring connected to the detection electrode, and the wiring may be provided on the main surface of the base substrate on the living body side.

  Thereby, the signal processing circuit can be electrically connected via the wiring.

  For example, in the biosensor according to one aspect of the present disclosure, an opening is provided at the position of the ground electrode that covers the wiring connected to the detection electrode when the base substrate is wound around the entire circumference of the predetermined part of the living body. Yes.

  Thereby, the signal processing circuit connected to the detection electrode can be placed in the opening.

  For example, in the biosensor according to one embodiment of the present disclosure, the ground electrode is formed in a region on the base substrate so as to surround the region where the detection electrode and the wiring connected to the detection electrode are provided in a plan view of the main surface. It may be provided.

  Thereby, the influence of external noise can be further reduced.

  For example, a biological sensor according to one embodiment of the present disclosure includes a signal processing circuit unit that is provided on a base substrate and includes an amplification circuit that amplifies a biological signal detected by a detection electrode, and the signal processing circuit unit detects the biological signal. It may be electrically connected to the electrode.

  As a result, an amplified signal strong against external noise can be obtained.

  For example, in the biosensor according to one embodiment of the present disclosure, the ground terminal of the amplifier circuit may be electrically connected to the ground electrode.

  As a result, the amplified signal is a signal based on the potential of the ground electrode.

  For example, the biosensor according to one embodiment of the present disclosure may include an antenna pattern provided at a position different from the detection electrode and the ground electrode on the main surface of the base substrate on the living body side.

  Thus, by providing an antenna pattern, if a communication circuit is provided, the obtained biological signal can be wirelessly transmitted to an external terminal. This eliminates the need for wiring for connecting the biosensor to an external terminal, and improves convenience. Further, since the antenna pattern is provided on the main surface of the base substrate on the living body side, it is possible to suppress the antenna pattern from being damaged by friction or the like.

  For example, in the biosensor according to an aspect of the present disclosure, the base substrate may be configured with a fiber cloth.

  Accordingly, the biological sensor can have at least one of flexibility and stretchability, and can follow the complex shape of the biological surface and deformation of the biological surface due to body movement.

  For example, in the biosensor according to one aspect of the present disclosure, the base substrate may be made of a resin material.

  Accordingly, the biological sensor can have at least one of flexibility and stretchability, and can follow the complex shape of the biological surface and deformation of the biological surface due to body movement.

  For example, in the biosensor according to one embodiment of the present disclosure, the base substrate may have air permeability.

  Thereby, the stuffiness at the time of mounting | wearing can be relieved and the feeling of wearing of a biosensor, ie, comfort, improves.

  In addition, a measurement method using the biosensor according to one embodiment of the present disclosure includes a belt-like base substrate that has at least one of flexibility and stretchability and can be wound around the entire circumference of a predetermined part of a living body. The at least one detection electrode that is provided on the main surface of the base substrate on the living body side and detects a biological signal of the living body and the detection electrode on the main surface of the base substrate on the living body side are provided at different positions. A biosensor comprising at least one ground electrode, and the biosensor is wound so that the ground electrode covers the detection electrode when wound around the entire circumference of a predetermined part of the living body, and is detected by the detection electrode Measure the vital signal.

  This makes it possible to stably detect a weak biological signal that is comfortable to wear.

  Hereinafter, embodiments of the present disclosure will be specifically described with reference to the drawings.

  It should be noted that each of the embodiments described below shows a comprehensive or specific example. Numerical values, shapes, materials, components, arrangement positions and connection forms of components, steps, order of steps, and the like shown in the following embodiments are merely examples, and are not intended to limit the present disclosure. In addition, among the constituent elements in the following embodiments, constituent elements that are not described in the independent claims indicating the highest concept are described as optional constituent elements. Also, the drawings are not necessarily shown strictly. In each figure, substantially the same configuration is denoted by the same reference numeral, and redundant description may be omitted or simplified.

  The various elements shown in the drawings are merely schematically shown for understanding of the present disclosure, and the dimensional ratio, appearance, and the like may be different from the actual ones.

  Hereinafter, the detection electrode and the ground electrode are collectively referred to as an “electrode”.

(Embodiment 1)
Hereinafter, the measurement method using the biosensor and the biosensor according to Embodiment 1 of the present disclosure will be described with reference to FIGS. 1A to 2. 1A is a perspective view schematically showing a biosensor 100a according to Embodiment 1. FIG. FIG. 1B is a perspective view schematically showing a state in which the biological sensor 100a according to Embodiment 1 is attached to a living body. 1C is a schematic cross-sectional view taken along line IC-IC in FIG. 1B. FIG. 1D is an enlarged view of a part of the schematic cross-sectional view of FIG. 1C. FIG. 2 is a diagram for explaining an example of use of the biosensor according to the first embodiment.

[Biosensor]
As shown in FIG. 1A, a biosensor 100a according to Embodiment 1 includes a band-shaped base substrate 1 that can be wound around the entire circumference of a predetermined part of a living body, and a main surface of the base substrate 1 on the living body side. And at least one detection electrode 2 for detecting a biological signal of the living body, and at least one ground electrode 3 provided at a position different from the detection electrode 2 on the main surface of the base substrate 1.

  In the biosensor according to the present disclosure, the base substrate 1 has at least one of flexibility and stretchability. You may have both flexibility and a stretching property. In the present embodiment, the base substrate 1 has flexibility and stretchability. Specific materials will be described later.

  In addition, as shown in FIG. 1B, in the biosensor 100a according to the present embodiment, the ground electrode 3 covers the detection electrode 2 when the base substrate 1 is wound around the entire circumference of a predetermined part of the living body. The ground electrode 3 is provided on the base substrate 1. More specifically, as shown in FIG. 1C, when the biosensor 100a is wound around a predetermined part of the living body over the entire circumference, the base electrode 3 covers the opposite side of the detection electrode 2 from the living body side. A ground electrode 3 is provided on the substrate 1.

  FIG. 1D is a partial cross-sectional view of the biosensor 100a when the biosensor 100a is wound around the entire circumference of a predetermined part of the living body. As shown in FIG. 1D, the detection electrode 2 and the ground electrode 3 are provided on the same surface of the base substrate 1 and are in contact with the surface of the living body. The ground electrode 3 goes around a predetermined part of the living body and covers the detection electrode 2 from the side opposite to the surface of the detection electrode 2 on the living body side. In this way, the ground electrode 3 covers the detection electrode 2 from the outside, so that external noise can be blocked. That is, the portion of the ground electrode 3 that covers the detection electrode 2 serves as a shield layer. Therefore, the biological sensor 100a according to the present embodiment can stably detect a weak biological signal by having the above configuration.

  In the present embodiment, as described above, the base substrate 1 has flexibility and stretchability. Since the base substrate 1 has flexibility, the biosensor 100a has flexibility. Furthermore, since the base substrate 1 has elasticity, the biosensor 100a can easily follow the shape of the living body surface and easily follow the movement of the living body, so that the connection reliability between the living body surface and the detection electrode 2 is reliable. Can be improved.

  Further, the expansion / contraction direction of the base substrate 1 may be a two-dimensional direction in the plane of the base substrate 1, and may be a three-dimensional direction including a direction perpendicular to the base substrate 1.

  Thus, even if the predetermined part of the living body around which the biosensor 100a is wound has a three-dimensionally complicated shape due to the base substrate 1 having flexibility and stretchability, the biosensor 100a is formed on the surface of the living body. It can be adhered along the shape. The biosensor 100a can expand and contract following a specific location on the surface of the living body where the expansion and contraction occurs due to the movement of the living body. Therefore, the adhesion between the surface of the living body and the detection electrode 2 and the ground electrode 3 provided on the main surface of the base substrate 1 on the living body side is maintained regardless of the shape and movement of the predetermined part where the biological sensor 100a is mounted. can do. Thereby, the position shift of an electrode and generation | occurrence | production of the noise by the adhesion defect between an electrode and a biological body surface can be suppressed. Moreover, the biosensor 100a can ensure favorable comfort without giving a restraint force with respect to a biological body, because the base substrate 1 has flexibility and stretchability as described above. Thereby, the biosensor 100a can be comfortably worn for a relatively long time, and a biosignal can be detected stably.

  The material of the base substrate 1 is not particularly limited as long as it imparts at least one of flexibility and stretchability to the base substrate 1. For example, it may be a fiber cloth or a resin material. Thereby, the living body sensor can follow the deformation of the living body surface due to the complicated shape and body movement of the living body surface.

  Examples of the fiber cloth include a nonwoven fabric, a woven fabric, and a knitted fabric. In addition, you may use the material which impregnated the elastomer in these fiber cloths as the material of a base base material.

  Moreover, as a resin material, an elastomer material, a rubber material, etc. are mentioned, for example. These resin materials may be used alone or in combination of two or more.

  The material of the base substrate may be an elastomer material or a rubber material used for the detection electrode 2, the ground electrode 3, and the wiring (not shown in FIGS. 1A to 1D). However, in that case, the base substrate 1 does not have conductivity and functions as an insulating layer.

  Moreover, the base substrate 1 may have air permeability. Thereby, the stuffiness at the time of mounting | wearing can be relieved and the feeling of wearing of the biosensor 100a, ie, comfort, improves.

  As shown in FIG. 1B, the biosensor 100a has a length that can be wound around the entire circumference of a predetermined part of the living body, and the detection electrode 2 and the ground are formed on the surface of the base substrate 1 in contact with the living body surface. An electrode 3 is arranged. The ground electrode 3 is insulated from the detection electrode 2 and is disposed at a separated position.

  One or more detection electrodes 2 may be provided, but when information is acquired as a differential signal, two detection electrodes 2 may be provided. At this time, the region where the detection electrode 2 is disposed is used as the detection unit 20.

  The detection electrodes 2 may be arranged in series or in an array. For example, by arranging a plurality of detection electrodes 2 in a series or two-dimensional array in the same direction as the direction in which the biosensor 100a is wound around the living body, a predetermined part of the living body, for example, an arm around which the biosensor 100a is wound or Biological signals over the entire circumference of a specific part such as a leg can be acquired. In addition, when the biological sensor 100a is wound around the living body, the propagation of the biological signal can be measured by arranging the detection electrodes 2 so as to be perpendicular to the living body. As described above, by providing multiple measurement points, a plurality of pieces of biological sensing information can be acquired even with a simple mounting method of “wrapping”. Furthermore, using a plurality of biological sensing information acquired in this way, a more accurate and complicated analysis becomes possible. For example, by measuring myoelectricity at multiple points, three-dimensional data analysis can be performed with a wider range of measurements. Thereby, information on the deep part of the living body can be acquired with high accuracy, and the propagation speed of myoelectricity can be analyzed three-dimensionally and with time. By using these pieces of information, it is possible to estimate the balance of muscle activity, the degree of tension, the degree of fatigue, and the like.

  Although not shown, the biosensor 100a according to the present embodiment has a wiring for extracting a signal from the detection electrode 2.

  For example, as shown in FIGS. 1A to 1D, the ground electrode 3 is arranged so as to cover the entire surface excluding the detection electrode 2 on the side in contact with the living body surface of the base substrate 1. And what is necessary is just to be arrange | positioned on the base base material 1 so that it can ground on a biological body surface. Thus, when the ground electrode 3 is in contact with the surface of the living body, the potential of the ground electrode 3 becomes the same as that of the surface of the living body. Hereinafter, this potential is referred to as a biological ground.

  In addition, the ground electrode 3 is arranged on the entire main surface of the base substrate 1 excluding the detection electrode 2 and wiring (not shown), so that a large area to be grounded on the surface of the living body can be secured. Furthermore, since the ground electrode 3 can average the biological signal detected from the ground electrode 3 by covering the entire circumference of the predetermined part of the living body, noise other than the target biological signal is detected from the detection electrode 2. It becomes possible to cancel.

  The pattern shape of the ground electrode 3 is not particularly limited as long as it forms the shield part 30 as described above and can be grounded with the living body surface. For example, as shown in FIG. 1A, it may be formed in a solid shape, or may be formed in a mesh shape, a lattice shape, a dendritic shape, a comb shape, a radial shape, a spiral shape, a wave shape, or the like. Note that these shapes may be combined.

  For example, the pattern shape of the ground electrode 3 may be a meander shape. Depending on the pattern shape of the ground electrode 3, the ground electrode 3 may be formed so that the ground electrode 3 follows deformation due to at least one of flexibility and stretchability of the base substrate 1. Thereby, the biosensor 100a can have at least one of flexibility and stretchability. Further, by arranging a number of meander-shaped ground electrodes 3 meandering in the same direction in the same direction with respect to the base substrate 1, anisotropy is imparted to at least one of the flexibility and the stretchability of the biosensor 100a. It is also possible.

  In addition, as described above, by forming the ground electrode 3 in a pattern shape with a gap, it is possible to improve the air permeability and moisture permeability as compared with the case where the ground electrode 3 is formed in a pattern shape without a gap. Thereby, the comfort of the biosensor 100a is improved.

  As shown in FIG. 1D, when the biosensor 100a according to the present embodiment is mounted on a predetermined part of the living body, the biosensor 100a is wound over the entire circumference of the predetermined part of the living body. At this time, since the ground electrode 3 covers the detection electrode 2, that is, the detection unit 20 where the detection electrode 2 is arranged, a part of the ground electrode 3 that covers the detection unit 20 serves as a shield layer. . In this way, a predetermined region of the biosensor 100a including a part of the ground electrode 3 serving as a shield layer is referred to as a shield portion 30.

  The ground electrode 3 is in contact with the surface of the living body when the living body sensor 100a is wound over the entire circumference of the predetermined part of the living body, and thus has the same potential as the potential of the living body surface. Therefore, the ground electrode 3 corresponding to the shield part 30 is also at the same potential as the biological ground. Thereby, the ground electrode 3 corresponding to the shield part 30 can be blocked to such an extent that electromagnetic noise from the outside (hereinafter simply referred to as “external noise”) can be sufficiently suppressed. In addition, since the shield part 30 has a structure that covers the entire outer peripheral part directly above the detection part 20, a higher shielding effect can be obtained. Therefore, the biosensor 100a according to the present embodiment includes the shield unit 30, and thus can reduce the influence of external noise when detecting a weak signal from the surface of the living body.

  As described above, in the biosensor 100a according to the present embodiment, the detection electrode 2 and the ground electrode 3 are arranged on the same plane, and when the biosensor 100a is attached to a predetermined part of the living body, A shield unit 30 having a common potential is configured to cover the detection unit 20. That is, the biosensor 100a has a configuration in which the detection electrode 2, the base substrate 1, the ground electrode 3, and the base substrate 1 are laminated in order from the living body side. The configuration described above can be realized simply by winding the biological sensor 100a around a predetermined part of the living body. Therefore, in the biosensor 100a, it is usually sufficient even if there is no configuration of an insulating layer that is necessary when the electrodes are multilayered and a conductive member that penetrates the insulating layer in order to electrically connect the electrodes. Demonstrate the function.

  Thus, since the biosensor 100a does not require a complicated multilayer structure, flexibility is not impaired. Therefore, when the living body moves (hereinafter referred to as “body movement”) and the three-dimensional shape of the living body surface can be followed, it becomes possible to maintain the adhesion between the living body surface and the electrode. Accordingly, it is possible to reduce so-called body movement noise due to a displacement between the living body surface and the electrode due to body movement and poor adhesion. Moreover, since the biosensor 100a has flexibility, it does not impair comfort. In addition, a complicated configuration such as a conductive member that penetrates the insulating layer causes stress to concentrate when the biosensor 100a expands and contracts following the body movement and the shape of the surface of the living body, causing connection failure such as disconnection. . However, since the biosensor 100a according to the present embodiment normally performs its function even without the complicated configuration required for multilayering of electrodes, it is poorly connected to a conductive member or the like that penetrates the insulating layer. It does not have a structure that causes Therefore, the biosensor 100a can obtain long-term connection stability as compared with a biosensor having multi-layered electrodes.

  Thus, the biometric sensor 100a according to the present embodiment can reduce the influence of external noise and body movement noise by a simple mounting method of winding around a living body. Moreover, since the biosensor 100a does not have a complicated configuration, it has flexibility to follow the body movement and the shape of the living body surface. Therefore, the biosensor 100a is unlikely to cause a connection failure such as disconnection. Moreover, since the biosensor 100a has flexibility, it is comfortable to wear and can be worn for a relatively long time.

  In addition, the means for winding and fixing the biosensor 100a according to the present embodiment around the living body is not particularly limited as long as it can be fixed at a desired arbitrary position. For example, a fixing member such as a hook-and-loop fastener such as Velcro (registered trademark), a snap button, or a belt that can be fixed by contacting the opposing surfaces may be used.

  Moreover, in the biosensor 100a, the base substrate 1 has a sufficient length that can be wound around the entire circumference of a predetermined part of the living body. Therefore, even if there is an individual difference in the size of the predetermined part of the living body, for example, the thickness of the arm or leg, the biological sensor 100a can be mounted according to the size of the predetermined part. Moreover, since the contact pressure to the living body surface can be adjusted by adjusting the tightening condition at the time of wearing, it can be worn comfortably. Furthermore, the adhesion between the living body surface and the electrode can be maintained.

[Measurement method using biological sensor]
For example, as shown in FIG. 2, the biosensor 100a according to the present embodiment is used by being wound around the entire circumference of a predetermined part of the living body (here, the thigh). In this example, the electromyogram during exercise is measured.

  In the measurement method using the biosensor according to the present embodiment, the above-described biosensor 100a is prepared, and the living body is covered so that the ground electrode 3 covers the detection electrode 2 when wound around the entire circumference of a predetermined part of the living body. The sensor 100a is wound around and the biological signal detected by the detection electrode 2 is measured.

  This makes it possible to stably detect a weak biological signal that is comfortable to wear.

(Embodiment 2)
Hereinafter, a biosensor and a measurement method using the biosensor according to the second embodiment of the present disclosure will be described with reference to FIGS. 3 and 4. FIG. 3 is a perspective view schematically showing a biosensor 100b according to the second embodiment. FIG. 4 is a diagram for explaining an example of use of the biosensor 100b according to the second embodiment. In addition, about the content which overlaps with the structure of the biosensor 100a which concerns on Embodiment 1, and the measuring method using the biosensor 100a, description is abbreviate | omitted here.

[Biosensor]
The biosensor 100b according to the present embodiment further includes a wiring 4 and a signal processing circuit unit 40 in addition to the configuration of the biosensor 100a according to the first embodiment.

  As shown in FIG. 3, the biological sensor 100b according to the present embodiment includes a signal processing circuit unit 40 having an amplification circuit for amplifying a biological signal, and the detection electrode 2 and the signal processing circuit unit 40 are connected to the wiring 4 as shown in FIG. Connected by. The ground electrode 3 is formed on the same surface so as to be insulated from the detection electrode 2 and the wiring 4. The ground electrode 3 is electrically connected to the ground terminal of the amplifier circuit of the signal processing circuit unit 40 by the wiring 4. Although not shown, the wiring 4 has an insulating layer on the surface on the living body side so as to be insulated from the surface of the living body.

  The biometric sensor 100b according to the present embodiment has a shield portion 30 (see FIG. 1D) having a common potential with the biogenic ground, as in the first embodiment, when the biosensor 100b is wound around and mounted on a predetermined part of the living body. ) Is configured to cover the outer peripheral portion directly above the region where the detection electrode 2, the wiring 4, and the signal processing circuit unit 40 are disposed. Therefore, in the biosensor 100b according to the present embodiment, it is possible to remove the influence of external noise not only on the detection electrode 2 but also on the wiring 4.

  The signal processing circuit unit 40 includes an amplification circuit that amplifies a biological signal, a filter that cuts a specific frequency, an AD conversion circuit that performs A / D (analog / digital) conversion on an acquired potential signal, and a personal computer. A communication circuit that transmits a signal to an external terminal may be provided.

  In the case of transmitting a signal by a wireless signal, when the biological sensor 100b is wound around and attached to the living body, an opening may be provided in a portion corresponding to the signal processing circuit unit 40 in a region where the shield portion is disposed. The signal processing circuit unit 40 may be attached or detached, and for example, a snap button may be used as an electrode.

  In addition, when a signal is transmitted to an external terminal by wiring or the like, it is not necessary to have an opening, and wiring for electrically connecting the signal processing circuit unit 40 provided on the base substrate 1 and the external terminal. You may provide a plug in the arbitrary locations of the biosensor 100b.

  Although not shown, in addition to the detection electrode 2 and the ground electrode 3, a reference electrode (reference electrode) is disposed in a region insulated from the detection electrode 2 and the ground electrode 3, and the reference electrode and the signal processing circuit unit 40 are disposed. And may be connected by wiring.

[Measurement method using biological sensor]
In the measurement method using the biosensor 100b according to the present embodiment, for example, the biosensor 100b is wound around the thigh and the myoelectricity is measured as in the case of the biosensor 100a according to the first embodiment. The biosensor 100b may be wound around and mounted on any part of the living body, but FIG. 4 shows an example in which the biosensor 100b is wound around the thigh.

  The biosensor 100b according to the present embodiment includes the wiring 4 and the signal processing circuit unit 40. Here, the signal processing circuit unit 40 includes an amplifier circuit, an AD conversion circuit, and a communication circuit. Therefore, in the measurement method using the biosensor 100b according to the present embodiment, an external terminal such as a tablet terminal is obtained via the wiring 4 and the signal processing circuit unit 40 after obtaining a biosignal from the detection unit 20. The data of the biological signal is transmitted to.

(Embodiment 3)
Hereinafter, a biosensor according to Embodiment 3 of the present disclosure and a measurement method using the biosensor will be described.

  FIG. 5A is a plan view schematically showing biosensor 100c according to Embodiment 3. 5B is a schematic cross-sectional view taken along line VB-VB in FIG. 5A. FIG. 5C is a diagram of the detection unit 20 viewed from the living body side when the biosensor 100c according to Embodiment 3 is attached to the living body. In FIG. 5C, the area corresponding to the shield part 30 is hatched. 5D is a schematic cross-sectional view taken along line VD-VD in FIG. 5C. FIG. 5D is a schematic cross-sectional view of the biosensor 100c shown in FIG. 5C as viewed from above. FIG. 5E is a schematic cross-sectional view taken along the line VD-VD when the signal processing circuit unit 40 is attached to the biosensor 100c according to Embodiment 3.

  In addition, about the content which overlaps with the structure of the biosensors 100a and 100b which concern on Embodiment 1 and 2, and the measuring method using the biosensors 100a and 100b, description is abbreviate | omitted here.

[Biosensor]
As shown in FIGS. 5A and 5B, in the biosensor 100c according to the present embodiment, the ground electrode 3 is a base substrate excluding a region where the detection electrode 2 and the wiring 4 connected to the detection electrode 2 are provided. It arrange | positions so that the whole surface of 1 main surface may be covered. At this time, the detection electrode 2 and the wiring 4 are disposed so as to be insulated from the ground electrode 3. 5C and 5D, in the biosensor 100c, the ground electrode 3 that covers the wiring 4 connected to the detection electrode 2 when the base substrate 1 is wound around the entire circumference of a predetermined portion of the living body. In other words, the opening 5 is provided at the location of the shield portion 30. At this time, a plurality of through holes 6 may be formed along the wiring 4 in the base substrate 1 corresponding to the wiring 4 connected to the detection electrode 2. These through holes 6 may be hollow, or the through holes 6 may be filled with a conductive material. Further, a metal snap button (not shown) may be disposed on the opening 5 side of the through hole 6. Furthermore, as shown in FIG. 5E, the biological sensor 100 c may be attached to the living body, and the signal processing circuit unit 40 may be disposed in the opening 5. At this time, the signal processing circuit unit 40 is fixed in the opening 5 through a metal snap button and can be electrically connected to the detection electrode 2 through the through hole 6. In the signal processing circuit unit 40, the ground terminal of the amplifier circuit is electrically connected to the ground electrode 3.

  The snap button may be fixed to the base substrate 1 so as not to wobble. The snap button may be made of a metal having low electrical resistance and mechanical strength, such as stainless steel. At this time, the snap button is preferably thin from the viewpoint of flexibility and comfort. Furthermore, the snap button may be arranged away from the detection unit 20 from the viewpoint of ensuring the adhesion between the living body surface and the detection electrode 2. Thereby, the influence of the reduction of the contact pressure to the living body surface in the detection part 20 can be disregarded. As described above in the first embodiment, also in the present embodiment, the biosensor 100c can adjust the contact pressure on the surface of the living body by adjusting the tightening condition at the time of wearing.

  Further, the length of the wiring 4 is arbitrary, but it is better not to be long from the viewpoint of reducing the influence of noise. For example, in the biosensor 100c according to the present embodiment, since the through hole 6 and the metal snap button (not shown) are arranged in the base substrate 1 corresponding to the wiring 4, the snap button is in the region of the detection unit 20. The wiring 4 may be formed to a length that does not affect the contact pressure. As described above, the wiring 4 has an insulating layer on the surface on the living body side.

[Measurement method using biological sensor]
In the measurement method using the biosensor 100c according to the present embodiment, for example, as with the biosensor 100a according to the first embodiment, the biosensor 100c is wound around the thigh to measure myoelectricity. The biosensor 100c may be wound around and attached to any part of the living body.

  In the biosensor 100c according to the present embodiment, the signal processing circuit unit 40 is attached to the opening 5 after the biosensor 100c is attached to the living body. Here, the signal processing circuit unit 40 includes an amplifier circuit, an AD conversion circuit, and a communication circuit. Therefore, in the measurement method using the biosensor 100c according to the present embodiment, an external terminal such as a tablet terminal is obtained via the wiring 4 and the signal processing circuit unit 40 after acquiring a biosignal from the detection unit 20. The data of the biological signal is transmitted to. Furthermore, in the biosensor 100c, the signal processing circuit unit 40 may include a display unit. The acquired biological signal is displayed on the display unit. Thereby, the user can confirm the acquired biological signal with a display part.

(Embodiment 4)
Hereinafter, a biosensor and a measurement method using the biosensor according to Embodiment 4 of the present disclosure will be described.

  FIG. 6A is a plan view schematically showing biosensor 100d according to Embodiment 4. 6B is a schematic cross-sectional view taken along line VIB-VIB in FIG. 6A. FIG. 6C is a diagram of the detection unit 20 viewed from the living body side when the living body sensor 100d according to Embodiment 4 is attached to the living body. In FIG. 6C, the area corresponding to the shield part 30 is hatched. 6D is a schematic cross-sectional view taken along line VID-VID in FIG. 6C. FIG. 6D is a schematic cross-sectional view of the biometric sensor 100d shown in FIG. 6C as viewed from above.

  In addition, description is abbreviate | omitted here about the content which overlaps with the structure of the biosensors 100a-100c which concern on Embodiment 1-3, and the measuring method using biosensors 100a-100c.

[Biosensor]
As shown in FIG. 6A, in the biosensor 100d according to Embodiment 4, the wiring 4 connected to the detection electrode 2 extends in the winding direction of the biosensor 100d, that is, in the direction perpendicular to the longitudinal direction. May be formed. Further, as shown in FIG. 6B, in the biosensor 100d, the ground electrode 3 constitutes the shield part 30 (see FIG. 1D) as in the first embodiment, and can be grounded to the surface of the living body. What is necessary is just to be arrange | positioned on the base material 1. FIG. That is, the ground electrode 3 may be referred to as a region (hereinafter, referred to as a “ground region”) that is in contact with a part of the surface of the living body, in addition to a region constituting the shield part 30 (hereinafter, may be referred to as a “shield region”). .). For example, the ground region may have the same area as the detection electrode 2. In this case, the ground electrode 3 a including the ground region and the ground electrode 3 b including the shield region may be connected by the wiring 4. Thereby, the ground electrode 3b including the shield region has the same potential as the ground electrode 3a including the ground region grounded to the living body.

  As shown in FIGS. 6C and 6D, when the biosensor 100d according to the present embodiment is wound around a predetermined part of the living body, the outer peripheral portion directly above the detection unit 20 has the same potential as the bioground. Covered by the shield part 30. Thus, the biosensor 100d has a structure shielded from external noise.

  In the biosensor 100d according to the present embodiment, unlike the other embodiments described above, the ground electrode 3 is not disposed so as to surround the detection electrode 2 and the wiring 4. Moreover, in this Embodiment, the base material 1 may have air permeability. Thereby, when the biosensor 100d is attached to a predetermined part of the living body, the biosensor 100d has improved air permeability in a region in close contact with the surface of the living body, and comfort is improved.

  In biosensor 100d, detection electrode 2 and signal processing circuit unit 40 are electrically connected as described above in the second or third embodiment.

[Measurement method using biological sensor]
As a measurement method using the biosensor 100d according to the present embodiment, any of the measurement methods of the above-described embodiments can be used.

(Embodiment 5)
Hereinafter, a biosensor and a measurement method using the biosensor according to the fifth embodiment of the present disclosure will be described.

  FIG. 7A is a plan view schematically showing biosensor 100e according to Embodiment 5. 7B is a schematic cross-sectional view taken along the line VIIB-VIIB in FIG. 7A when the biological sensor 100e in FIG. 7A is wound around the living body.

  In addition, description is abbreviate | omitted here about the content which overlaps with the measuring method using the biosensors 100a-100d and biosensors 100a-100d which concern on Embodiment 1-4 mentioned above.

[Biosensor]
As shown in FIG. 7A, the biosensor 100e according to the present embodiment includes an antenna pattern 7 provided at a position different from the detection electrode 2 and the ground electrode 3 on the main surface of the base substrate 1. Thus, since the antenna pattern 7 is provided on the main surface of the base substrate 1, it is possible to prevent the antenna pattern 7 from being damaged due to friction with the outside. The type of antenna pattern 7 in the present embodiment is not particularly limited as long as radio waves can be transmitted. For example, a dipole antenna may be used.

  In biosensor 100e, detection electrode 2 and signal processing circuit unit 40 are electrically connected as described above in other embodiments. For example, as shown in FIGS. 7A and 7B, when the signal processing circuit unit 40 is provided on the base substrate 1, the wiring 4 extending from the signal processing circuit unit 40 in the direction of the antenna pattern 7 is provided. A plurality of through holes 6 are arranged in the base substrate 1 along the extended wiring 4. As described above in Embodiment 3, the through-hole 6 may be filled with a conductive material, for example. Further, a metal snap button (not shown) may be disposed in the through hole 6. Thereby, the communication circuit of the signal processing circuit unit 40 is electrically connected to the terminal 8 of the antenna pattern 7 through the through hole 6 filled with the conductive material. Alternatively, it is electrically connected to the terminal 8 of the antenna pattern 7 via a metal snap button (not shown) disposed in the through hole 6.

  In the signal processing circuit unit 40, the ground terminal of the amplifier circuit is electrically connected to the ground electrode 3.

  In the present embodiment, the configuration in which the signal processing circuit unit 40 is provided on the base substrate 1 has been described. However, the signal processing circuit unit 40 may not be provided on the base substrate 1. In this case, for example, the signal processing circuit unit 40 is attached to the opening 5 (FIG. 5E) after the biological sensor 100e is wound around the living body, and the communication circuit of the signal processing circuit unit 40 and the antenna pattern 7 are electrically connected. You may comprise. As described above in the third embodiment, the opening 5 is formed on the ground electrode 3 that covers the wiring 4 connected to the detection electrode 2 when the base substrate 1 is wound around the entire circumference of a predetermined part of the living body. It is provided at the location, that is, at the location of the shield part 30. At this time, the signal processing circuit unit 40 is fixed to a metal snap button (not shown) provided on the opening 5 side of the through hole 6 and is electrically connected to the detection electrode 2 through the through hole 6. Yes. Further, the terminal 8 of the antenna pattern 7 is disposed at the end of the opening 5 on the antenna pattern 7 side. As a result, the communication circuit of the signal processing circuit unit 40 is electrically connected to the antenna pattern 7 via the terminal 8.

[Measurement method using biological sensor]
As the measurement method using the biosensor 100e according to the present embodiment, any of the measurement methods of the above-described embodiments can be used. Furthermore, in the present embodiment, the biological sensor 100e includes an antenna pattern, so that after acquiring a biological signal from the detection unit 20, an external terminal is connected via the wiring 4, the signal processing circuit unit 40, and the antenna pattern 7. For example, biosignal data is wirelessly transmitted to a tablet terminal or the like. Thereby, unlike the case of wired connection, wiring or the like is not necessary when the biometric sensor 100e is connected to an external terminal, and convenience is improved.

  In addition, since biometric sensor 100e according to the present embodiment performs wireless communication with an external terminal as described above, it is not necessary to connect a wiring to be connected to the outside. Therefore, in this embodiment, a plurality of biological sensors 100e may be attached to different predetermined parts of the living body, and biological signals may be measured simultaneously. By using the biological sensing information obtained in this way, more accurate and complicated analysis can be performed.

  As described above, the biosensor and the measurement method using the biosensor according to the present disclosure have been described based on the embodiments. However, the present disclosure is not limited to these embodiments. Unless it deviates from the gist of the present disclosure, various modifications conceived by those skilled in the art and other forms constructed by combining some components in the embodiments are also within the scope of the present disclosure. included.

  Note that the biosensor according to the present disclosure may be wound around a predetermined part of the living body two or more times. Thereby, the shielding effect with respect to external noise can further be improved.

  Moreover, in the said embodiment, although the example which measures one biological signal in the predetermined site | part of a biological body was shown, it is an electrode structure which can measure two or more biological signals, for example, the structure where four or more detection electrodes are arrange | positioned. There may be. As a result, the biological signal can be measured at multiple points, and more accurate and complicated analysis can be performed.

  The biosensor and the measurement method using the biosensor according to the present disclosure are comfortable to wear when the biosensor is mounted, and can detect a weak biosignal stably and with high sensitivity. It can be used to monitor daily biological sensing information. In addition, it is possible to attach a plurality of biosensors to a plurality of measurement parts of a living body and simultaneously measure a biosignal, so that it can be used for more advanced data analysis in academic and medical settings. .

DESCRIPTION OF SYMBOLS 1 Base base material 2 Detection electrode 3, 3a, 3b Ground electrode 4 Wiring 5 Opening 6 Through-hole 7 Antenna pattern 8 Terminal 20 Detection part 30 Shield part 40 Signal processing circuit unit 100a-100e Biosensor

Claims (11)

A belt-like base substrate having at least one of flexibility and stretchability and capable of being wound around the entire circumference of a predetermined part of a living body;
At least one detection electrode provided on a main surface of the base substrate on the living body side for detecting a biological signal of the living body;
At least one ground electrode provided at a position different from the detection electrode on the main surface of the base substrate;
With
The ground electrode is provided on the base substrate so that the ground electrode covers the detection electrode when the base substrate is wound around the entire circumference of the predetermined part of the living body.
Biosensor. Provided with a wiring connected to the detection electrode, the wiring is provided on the main surface of the base substrate,
The biosensor according to claim 1. An opening is provided at the position of the ground electrode that covers the wiring connected to the detection electrode when the base substrate is wound around the entire circumference of the predetermined portion of the living body.
The biosensor according to claim 2. The ground electrode is provided in a region on the base substrate so as to surround a region where the detection electrode and the wiring connected to the detection electrode are provided in a plan view of the main surface.
The biosensor according to any one of claims 1 to 3. A signal processing circuit unit provided on the base substrate and having an amplification circuit for amplifying a biological signal detected by the detection electrode, the signal processing circuit unit being electrically connected to the detection electrode;
The biosensor according to any one of claims 1 to 4. The ground terminal of the amplifier circuit is electrically connected to the ground electrode.
The biological sensor according to claim 5. An antenna pattern provided at a position different from the detection electrode and the ground electrode on the main surface of the base substrate;
The biosensor according to any one of claims 1 to 6. The base substrate is composed of a fiber cloth,
The biosensor according to any one of claims 1 to 7. The base substrate is made of a resin material,
The biosensor according to any one of claims 1 to 7. The base substrate has air permeability;
The biosensor according to any one of claims 1 to 9. A strip-shaped base substrate having at least one of flexibility and stretchability, and capable of being wound around the entire circumference of a predetermined part of a living body, provided on the living body side main surface of the base substrate, A biosensor is provided, comprising: at least one detection electrode that detects a biological signal of a living body; and at least one ground electrode provided at a position different from the detection electrode on the main surface of the base substrate. ,
Wrapping the biological sensor so that the ground electrode covers the detection electrode when wound around the entire circumference of the predetermined part of the living body,
Measuring the biological signal detected by the detection electrode;
Measurement method using a biosensor.

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