JP2018164616A - Ophthalmologic apparatus - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide an apparatus including a function for suitably performing positioning between an optical system for acquiring data of an eye to be examined and the eye to be examined.SOLUTION: An ophthalmologic apparatus includes: an optical system including an illumination system for emitting illumination light to an eye to be examined, an anterior eye part observation system which guides light from an anterior eye part of the eye to be examined where the illumination light is emitted by the illumination system to a light field camera, and a measurement system 50 for optically acquiring data of the eye to be examined; a support part for supporting a face of a subject; a driving part for moving the optical system and the support part relatively in an optical axis direction of the optical system; an analysis part 210 for obtaining a movement target position by analyzing image data obtained by the light field camera; and a control part 100 for relatively moving the optical system and the support part by controlling the driving part based on the movement target position.SELECTED DRAWING: Figure 4

Description

  The present invention relates to an ophthalmologic apparatus.

  The ophthalmologic apparatus includes an ophthalmologic photographing apparatus for obtaining an image of the eye to be examined and an ophthalmologic measuring apparatus for measuring the characteristics of the eye to be examined.

  As an example of an ophthalmologic photographing apparatus, an optical coherence tomography (Optical Coherence Tomography, OCT) is used to obtain a tomographic image, a fundus camera for photographing a fundus, and laser scanning using a confocal optical system. There are a scanning laser opthalmoscope (SLO) that obtains an image, a slit lamp that obtains an image by cutting an optical slice of the cornea using slit light, and the like.

  Examples of ophthalmic measuring devices include an ocular refraction examination device (refractometer, keratometer) that measures the refractive characteristics of the eye to be examined, a tonometer, a specular microscope that obtains corneal properties (corneal thickness, cell distribution, etc.), Hartmann There is a wave front analyzer that obtains aberration information of the eye to be examined using a shack sensor.

  In an ophthalmic examination using such an ophthalmologic apparatus, the alignment between the apparatus optical system and the eye to be examined is extremely important from the viewpoint of the accuracy and accuracy of the examination. This alignment is called alignment. The alignment includes an operation of aligning the optical axis of the apparatus optical system with the axis of the eye to be examined (XY alignment), and an operation of adjusting the distance between the eye to be examined and the apparatus optical system to a predetermined distance (Z alignment). Is included.

  Further, the specular microscope is required to perform Z alignment with respect to the apex of the corneal endothelium. However, when the subject's eye is observed from the front, the corneal endothelium cannot be observed and the apex of the corneal endothelium cannot be specified.

  Various methods have been proposed as an alignment method in such an ophthalmologic apparatus. For example, Patent Document 1 discloses a method of performing XY alignment by projecting light onto a cornea and detecting a reflected image (Purkinje image). For example, Patent Document 2 discloses a technique for performing Z alignment by an optical lever method.

  For example, in Patent Document 3, two or more photographed images obtained by photographing the anterior segment from different directions are analyzed to identify the three-dimensional position of the eye to be examined, and XY alignment is performed based on the three-dimensional position. A technique for performing both Z alignments is disclosed.

Japanese Patent Laid-Open No. 10-024019 Japanese Patent Laying-Open No. 2015-146859 JP 2013-248376 A

  However, in the methods disclosed in Patent Literature 1 and Patent Literature 2, the dynamic range representing the detectable range of the relative position between the apparatus optical system and the eye to be examined is narrow. Therefore, if the apparatus optical system and the eye to be examined are not aligned within a certain range, alignment cannot be performed using these methods.

  In contrast, the method disclosed in Patent Document 3 has a wider dynamic range than the methods disclosed in Patent Document 1 and Patent Document 2. However, depending on the shape of a part of the subject's face (for example, the nose), vignetting may occur in the captured image. Therefore, it may become impossible to specify the three-dimensional position of the eye to be examined and perform alignment.

  The present invention has been made in view of such circumstances, and an object of the present invention is to newly perform alignment between an apparatus optical system for acquiring data of an eye to be examined and the eye to be examined. To provide technology.

The first aspect of the ophthalmologic apparatus according to the embodiment includes an illumination system that irradiates an eye to be inspected with illumination light, and a light field camera that emits light from the anterior eye portion of the eye to be inspected that is illuminated by the illumination system An anterior ocular segment observation system, an optical system including a measurement system for optically acquiring data of the eye to be examined, a support unit for supporting the face of the subject, the optical system and the support Based on the movement target position, a drive unit that moves relative to the optical axis direction of the optical system, an analysis unit that obtains a movement target position by analyzing image data obtained by the light field camera, and And a control unit that controls the driving unit to move the optical system and the support unit relative to each other.
Further, in the second aspect of the ophthalmologic apparatus according to the embodiment, in the first aspect, the analysis unit has two or more eye images to be examined corresponding to two or more image plane positions in the optical axis direction based on the image data. And the movement target position may be obtained based on the image quality of the two or more eye images thus generated.
In the third aspect of the ophthalmologic apparatus according to the embodiment, in the second aspect, the two or more subject eye images include a subject eye image corresponding to a current relative position between the optical system and the support unit, The analysis unit may obtain the movement target position based on an image plane position corresponding to an eye image having a higher image quality than the eye image corresponding to the current relative position.
In the fourth aspect of the ophthalmologic apparatus according to the embodiment, in the second aspect or the third aspect, the analysis unit has an image plane position corresponding to the eye image with the highest image quality among the two or more eye images to be examined. The movement target position may be obtained based on the above.
In the fifth aspect of the ophthalmic apparatus according to the embodiment, in any one of the first aspect to the fourth aspect, the drive unit relatively moves the optical system and the support unit in the optical axis direction of the optical system. The analysis unit specifies a feature region corresponding to a feature part of the eye to be examined based on the image data, and the control unit controls the drive unit based on the feature region. Thus, the optical system and the support portion may be relatively moved in a direction intersecting the optical axis direction.
In the sixth aspect of the ophthalmic apparatus according to the embodiment, in the fifth aspect, the control unit intersects the optical axis direction by the drive unit in parallel with the movement control in the optical axis direction by the drive unit. The movement control in the direction to be performed may be performed.
In the seventh aspect of the ophthalmologic apparatus according to the embodiment, in the fifth aspect or the sixth aspect, the optical system is arranged substantially coaxially with the optical path of the anterior ocular segment observation system, and the first alignment is performed on the eye to be examined. A first alignment optical system for projecting light and detecting a first reflected light of the first alignment light from the eye to be examined; and a second alignment from the optical axis of the anterior ocular segment observation system to the eye to be examined. A second alignment optical system for projecting light and detecting a second reflected light of the second alignment light from the eye to be examined, wherein the control unit is configured to control the optical system based on the movement target position. And the support part may be moved relative to each other, and then fine alignment control may be performed to control the driving part based on at least one of the detection result of the first reflected light and the detection result of the second reflected light.
In the eighth aspect of the ophthalmologic apparatus according to the embodiment, in any one of the first to sixth aspects, the optical system is disposed substantially coaxially with the optical path of the anterior ocular segment observation system, and is applied to the eye to be examined. A first alignment optical system configured to project a first alignment light and detect a first reflected light of the first alignment light from the eye to be examined; and the analysis unit is configured to perform the first alignment based on the image data. The size of the alignment bright spot image based on the alignment light may be obtained, and the movement target position may be obtained based on the obtained size.
Further, in the ninth aspect of the ophthalmologic apparatus according to the embodiment, in the eighth aspect, the analysis unit includes two or more eye images corresponding to two or more image plane positions in the optical axis direction based on the image data. And the movement target position may be obtained based on the image plane position corresponding to the eye image having the smallest size of the alignment bright spot image among the generated two or more eye images to be examined.
In the tenth aspect of the ophthalmologic apparatus according to the embodiment, in the eighth aspect or the ninth aspect, the optical system projects second alignment light onto the eye to be examined from outside the optical axis of the anterior ocular segment observation system. A second alignment optical system for detecting a second reflected light of the second alignment light from the eye to be examined, and the control unit includes the optical system and the support unit based on the movement target position. After the relative movement, precise alignment control for controlling the drive unit based on at least one of the detection result of the first reflected light and the detection result of the second reflected light may be performed.
Moreover, the eleventh aspect of the ophthalmic apparatus according to the embodiment may include the light field camera in any one of the first to tenth aspects.
In addition, it is possible to combine arbitrarily the structure which concerns on the above-mentioned several aspect.

  ADVANTAGE OF THE INVENTION According to this invention, it is possible to provide the new technique for suitably performing position alignment between the apparatus optical system for acquiring the data of the eye to be examined, and the eye to be examined.

It is a schematic diagram showing an example of composition of an ophthalmology device concerning an embodiment. It is a schematic diagram showing an example of composition of an ophthalmology device concerning an embodiment. It is the schematic showing an example of the structure of the optical system of the ophthalmologic apparatus which concerns on embodiment. It is a schematic block diagram showing an example of the composition of the control system of the ophthalmic device concerning an embodiment. It is a schematic block diagram showing an example of the composition of the control system of the ophthalmic device concerning an embodiment. It is a flowchart showing the operation example of the ophthalmologic apparatus which concerns on embodiment. It is a flowchart showing the operation example of the ophthalmologic apparatus which concerns on embodiment. It is the schematic for demonstrating the process which the ophthalmologic apparatus which concerns on embodiment performs. It is a schematic block diagram showing an example of the composition of the control system of the ophthalmologic apparatus concerning the modification of an embodiment.

  An example of an embodiment of an ophthalmologic apparatus according to the present invention will be described in detail with reference to the drawings. In addition, it is possible to use the description content of the literature referred in this specification, and arbitrary well-known techniques for the following embodiment.

  The ophthalmologic apparatus according to the present invention is used for optical examination of an eye to be examined. As described above, such an ophthalmologic apparatus includes an ophthalmologic photographing apparatus and an ophthalmologic measurement apparatus. Examples of the ophthalmologic photographing apparatus include an optical coherence tomometer, a fundus camera, a scanning laser ophthalmoscope, and a slit lamp. In addition, examples of the ophthalmologic measurement apparatus include an eye refraction inspection apparatus, a tonometer, a specular microscope, and a wave front analyzer. In the following embodiments, a case where the present invention is applied to an ophthalmologic apparatus provided with an observation system for observing (photographing) an eye to be examined and a measurement system for optically acquiring data of the eye to be examined will be described in detail. However, the present invention can be applied to any other ophthalmic apparatus.

  In the following, the optical axis direction of the device optical system is the Z direction (front-rear direction), the horizontal direction orthogonal to the optical axis of the device optical system is X direction (left-right direction), and the vertical direction is orthogonal to the optical axis of the device optical system. Is the Y direction (vertical direction).

<Configuration>
1 and 2 schematically show an example of a schematic configuration of the ophthalmologic apparatus according to the embodiment. FIG. 1 is a schematic diagram of an external configuration of an ophthalmologic apparatus 1 according to an embodiment as viewed from the subject side. FIG. 2 shows a schematic diagram of the external configuration of the ophthalmologic apparatus 1 as viewed from the side of the subject.

  The ophthalmologic apparatus 1 accommodates an optical system (apparatus optical system) for examining the eye to be examined. As shown in FIGS. 1 and 2, the ophthalmologic apparatus 1 includes a base 410, a housing 420 provided on the base 410, and a lens housing that can move three-dimensionally (in the XYZ directions) relative to the base 410. Part 430. The base 410 stores a drive system such as an optical system drive unit, which will be described later, and an arithmetic control circuit. The housing 420 stores the above optical system. The lens accommodating portion 430 is provided so as to protrude from the front surface of the housing 420 and accommodates an objective lens 24 described later. 1 and FIG. 2 may be provided so as not to protrude from the front surface of the housing 420. At least one of the housing 420 and the lens housing portion 430 may be configured to be movable with respect to the base 410.

  The ophthalmologic apparatus 1 is provided with a chin rest and a forehead pad that are fixed to the base 410 and support the face of the subject. The chin rest and the forehead support correspond to the support portion 440 shown in FIGS. 1 and 2.

[Optical system]
FIG. 3 shows a configuration example of the optical system of the ophthalmologic apparatus 1 according to the embodiment.

  The ophthalmic apparatus 1 includes an optical unit 2 in which an apparatus optical system is accommodated. The optical unit 2 includes an optical system for observing the anterior segment Ea of the eye E. The ophthalmologic apparatus 1 is provided with an arithmetic control unit and a user interface unit. The arithmetic control unit includes a computer that executes various arithmetic processes and control processes. The user interface unit is used to display an observation image or a captured image acquired using the optical unit 2 or to input an instruction to the ophthalmologic apparatus 1.

[Optical unit]
The optical unit 2 is provided with an optical system for acquiring a two-dimensional image (anterior eye image) of the anterior eye portion Ea of the eye E to be examined. The anterior segment image includes an observation image, a captured image, and the like. The observation image is, for example, a monochrome moving image formed at a predetermined frame rate using near infrared light. The captured image may be, for example, a color image obtained by flashing visible light, or a monochrome still image using near infrared light or visible light as illumination light. The optical unit 2 may be configured to be able to acquire images other than these, for example, a fluorescein fluorescent image, an indocyanine green fluorescent image, a spontaneous fluorescent image, and the like.

  The optical unit 2 is provided with an illumination system 10 and an anterior ocular segment observation system 20. The illumination system 10 irradiates illumination light to the anterior eye portion Ea of the subject whose face is fixed to the chin rest and the forehead. The anterior ocular segment observation system 20 guides the reflected light of the illumination light to a light field camera 21 that is an imaging device.

  The illumination system 10 includes an anterior segment illumination light source 11. The anterior segment illumination light source 11 irradiates the anterior segment Ea of the eye E with illumination light. The anterior segment illumination light source 11 irradiates the anterior segment Ea of the eye E with illumination light from outside the optical axis of the anterior segment observation system 20. The anterior segment illumination light source 11 includes, for example, a halogen lamp or an LED. The anterior segment illumination light source 11 emits near infrared light as illumination light. In FIG. 3, a plurality of anterior segment illumination light sources 11 are provided around the optical axis of the anterior segment observation system 20.

  The anterior ocular segment observation system 20 includes a light field camera 21, a relay lens 22, a diaphragm 23, and an objective lens 24. The light field camera 21 may be provided outside the anterior ocular segment observation system 20.

  Between the relay lens 22 and the diaphragm 23, a beam splitter BS1 for combining an optical path of an XY alignment optical system 30 (described later) with an optical path of the anterior ocular segment observation system 20 is provided. Further, between the diaphragm 23 and the objective lens 24, an optical path of the measurement system 50 described later is combined with an optical path of the anterior segment observation system 20, or an optical path of the anterior segment observation system 20 and an optical path of the measurement system 50 are combined. A beam splitter BS2 is provided for separating the optical path of the measurement system 50 from the combined optical path.

  The reflected light from the anterior segment Ea of the eye E to which the illumination light from the anterior segment illumination light source 11 is irradiated enters the objective lens 24. The reflected light is refracted by the objective lens 24, passes through the beam splitter BS 2, passes through the opening of the diaphragm 23, passes through the beam splitter BS 1, passes through the relay lens 22, and forms an image on the light field camera 21. The The light field camera 21 detects reflected light at a predetermined frame rate, for example. On the user interface unit, an anterior eye image (observation image) at an arbitrary image plane position based on the reflected light detected by the light field camera 21 is displayed.

  The light field camera 21 according to the embodiment is a photographing device for acquiring an image (light field image) at an arbitrary image plane position in the optical axis direction (Z direction) of the anterior ocular segment observation system 20 after photographing. Thereby, an image at a desired image plane position can be acquired after shooting. Such a light field camera 21 has, for example, a microlens array type configuration. In this case, the light field camera 21 includes a microlens array and an image sensor. The microlens array is disposed between the eye E and the image sensor. The microlens array includes a plurality of microlenses arranged in a matrix on the focal plane. The plurality of microlenses are arranged such that the optical axis direction substantially coincides with the optical axis direction of the anterior ocular segment observation system 20. The image sensor includes a plurality of pixels arranged in a matrix corresponding to the plurality of microlenses, and is disposed at a position separated by a predetermined distance with respect to the microlens array. The light refracted by each microlens enters a plurality of pixels corresponding to the microlens. Thereby, the plurality of pixels output detection results (image data) corresponding to the passing positions and directions of the light rays incident on the focal plane. If necessary, a main lens may be disposed between the relay lens 22 and the microlens array.

  The arithmetic control unit generates an image at an arbitrary image plane position by performing a known deconvolution process (image restoration process) on the detection results (image data) output from the plurality of pixels of the light field camera 21. It is possible.

  In this embodiment, rough Z alignment is performed using the light field camera 21 as described later.

(XY alignment optical system)
The XY alignment optical system 30 includes an alignment index light source (point light source) 31 including a light emitting diode that emits near infrared light, and a lens 32.

  The alignment light output from the alignment index light source 31 is refracted by the lens 32 and reflected toward the objective lens 24 by the beam splitter BS1. The light beam reflected by the beam splitter BS1 passes through the aperture of the diaphragm 23, passes through the beam splitter BS2, and is guided to the cornea of the eye E as a parallel light beam through the objective lens 24.

  Reflected light from the cornea surface by the parallel light beam guided to the cornea passes through the objective lens 24, passes through the beam splitter BS2, passes through the opening of the diaphragm 23, passes through the beam splitter BS1, and passes through the relay lens 22. An image is formed on the light field camera 21 via the route. The light field camera 21 forms an image based on the Purkinje image (bright spot) of the alignment light. Thereby, the anterior eye part image of the eye E and the bright spot image by the Purkinje image of the alignment light are simultaneously displayed on the user interface part. When performing XY alignment manually, the user performs an operation of moving the optical system so as to guide the bright spot image within the alignment mark. When performing alignment automatically, the arithmetic control unit controls a moving mechanism for moving the optical system so as to cancel the displacement of the bright spot image with respect to the alignment mark.

  The ophthalmologic apparatus 1 is provided with a Z alignment optical system 40 for performing Z alignment.

(Z alignment optical system)
The Z alignment optical system 40 includes a divergent light projection system and a divergent light receiving system. The divergent light projection system includes a light source 41 arranged outside the optical axis of the anterior ocular segment observation system 20. The divergent light receiving system includes a condenser lens 42 and a line sensor 43. The light source 41 outputs divergent light that is near infrared light. The divergent light is projected toward the cornea obliquely with respect to the cornea of the eye E to be examined (obliquely with respect to the optical axis of the anterior segment observation system 20).

  The condenser lens 42 is disposed on an optical axis that is symmetrical with respect to the optical axis of the divergent light projection system with respect to the optical axis of the anterior ocular segment observation system 20. The condensing lens 42 condenses the reflected light of the divergent light projected from the light source 41 toward the cornea onto the light receiving surface (detection surface) of the line sensor 43. The line sensor 43 is disposed at a position optically conjugate with the Purkinje image of the cornea of the light source 41.

  The line sensor 43 is provided with a plurality of light receiving elements (detecting elements) arranged so as to correspond to the optical axis direction (Z direction) of the anterior ocular segment observation system 20. Each light receiving element is assigned a position (address) in advance. When the line sensor 43 receives the reflected light of the diverging light projected from the light source 41 toward the cornea, the line sensor 43 can output a Z alignment signal corresponding to the light receiving position in the line sensor 43. The Z alignment signal includes information indicating that the reflected light has been received and information indicating the light receiving element that has received the reflected light in the line sensor 43 (address, information indicating the light receiving position of the reflected light).

  The barycentric position of the intensity distribution of the reflected light of the divergent light corresponds to the barycentric position of the intensity distribution of the reflected light beam on the surface of the cornea (corneal epithelium). When the optical unit 2 is moved in the Z direction with respect to the eye E, the light receiving position of the reflected light in the line sensor 43 moves. When coarse Z alignment (coarse alignment in the optical axis direction of the anterior ocular segment observation system 20) is completed, the position of the center of gravity is set to be within the detection range of the line sensor 43, for example. Therefore, the position in the front-rear direction (Z direction) of the optical unit 2 with respect to the surface of the cornea can be specified with reference to the light receiving position (address) detected as the barycentric position in the line sensor 43. Thus, precise Z alignment can be performed by moving the optical unit 2 in the front-rear direction so that the center of gravity is positioned at the center of the line sensor 43. Although the center of gravity position of the intensity distribution of the reflected light beam is obtained, the peak position of the intensity distribution of the reflected light beam may be obtained.

(Measurement system)
The measurement system 50 includes a known reflex measurement optical system for performing reflex measurement. For example, the measurement system 50 includes a projection system that projects a measurement pattern light beam onto the eye E and a light receiving system that receives return light from the eye E. The measurement pattern light beam projected by the projection system is reflected by the beam splitter BS2 toward the objective lens 24, refracted by the objective lens 24, and projected onto the eye E. The measurement pattern light beam projected onto the eye E passes through the periphery of the pupil of the eye E and is projected onto the fundus of the eye E. The return light of the measurement pattern light beam reflected from the fundus exits from the center of the pupil, passes through the same path as the measurement pattern light beam, and is received by the image sensor provided in the light receiving system of the measurement system 50. The arithmetic control unit analyzes the image based on the return light based on the detection result of the return light from the eye E by the light receiving system, and calculates the spherical power, the astigmatism power, the astigmatism axis angle, and the like as the refractive power of the eye E. Ask.

  Note that the measurement system 50 may include an optical system for performing another objective measurement such as kerato measurement.

  Such an ophthalmologic apparatus 1 may be provided with a fixation optical system that projects a fixation light beam onto the eye E to be examined. For example, the optical path of the fixation optical system is combined with the optical path of the anterior ocular segment observation system 20 between the beam splitter BS2 and the light field camera 21 in the anterior ocular segment observation system 20. That is, the fixation light flux is guided to the eye E through the optical path of the anterior ocular segment observation system 20. The fixation light beam projected by the fixation optical system is transmitted through the beam splitter BS2, refracted by the objective lens 24, and projected onto the fundus through the pupil of the eye E to be examined. It is possible to give an adjustment stimulus to the eye to be examined by moving the fixation target in the optical axis direction, or to change the fixation position of the eye E by changing the projection position of the fixation light flux on the fundus. is there.

[Calculation control unit]
The configuration of the arithmetic control unit will be described. The arithmetic control unit controls each unit of the optical unit 2 and the user interface unit 300. For example, the arithmetic and control unit causes the user interface unit 300 to display an anterior segment image of the eye E to be examined. The arithmetic control unit includes, for example, a microprocessor, a RAM (Random Access Memory), a ROM (Read Only Memory), a hard disk drive, a communication interface, and the like, as in a conventional computer. A computer program for controlling the ophthalmologic apparatus 1 is stored in a storage device such as a hard disk drive. The arithmetic control unit may include an operation device (input device) such as a keyboard and a mouse, and a display device such as an LCD.

[Control system]
The configuration of the control system of the ophthalmologic apparatus 1 will be described with reference to FIG. In FIG. 4, some components of the ophthalmologic apparatus 1 are omitted, and components particularly necessary for describing this embodiment are selectively shown.

(Control part)
The control system of the ophthalmologic apparatus 1 is configured around the control unit 100. The control unit 100 includes, for example, a microprocessor, RAM, ROM, hard disk drive, communication interface, and the like. The control unit 100 is provided with a main control unit 110 and a storage unit 120.

(Main control unit)
The main control unit 110 performs the various controls described above. For example, the main control unit 110 controls turning on and off the anterior segment illumination light source 11, the alignment index light source 31, and the light source 41, photographing control of the light field camera 21, detection control of the line sensor 43, control of the measurement system 50, and the like. I do. The main control unit 110 controls the optical system driving unit 2A, the data processing unit 200, the user interface unit 300, and the like. The main control unit 110 can also control the diaphragm 23.

  The optical system driving unit 2A drives a moving mechanism that three-dimensionally moves the optical unit 2 (device optical system) shown in FIG. The moving mechanism includes a holding member that holds the optical unit 2, an actuator that generates a driving force for moving the holding member, and a transmission mechanism that transmits the driving force. The actuator is constituted by, for example, a pulse motor. The transmission mechanism is configured by, for example, a combination of gears, a rack and pinion, or the like. The main control unit 110 can move the optical system provided in the ophthalmologic apparatus 1 three-dimensionally by controlling the optical system driving unit 2A. This control is used in alignment and tracking. Tracking refers to moving the apparatus optical system in accordance with the movement of the eye E. When tracking is performed, alignment and focusing are performed in advance. Tracking maintains a suitable positional relationship in which alignment and focus are achieved by moving the apparatus optical system in real time according to the position and orientation of the eye E based on an image obtained by taking a moving image of the eye E. It is a function.

(Memory part)
The storage unit 120 stores various data. Examples of data stored in the storage unit 120 include image data of an anterior segment image, eye information to be examined, and the like. The eye information includes information about the subject such as the patient ID and name, information about the subject's disease name (such as glaucoma and cataract), and information about the eye such as left / right eye identification information. including. The storage unit 120 stores various programs and data for operating the ophthalmologic apparatus 1.

(Data processing part)
The data processing unit 200 performs various data processing (image processing) and analysis processing on the image data obtained by the light field camera 21. For example, the data processing unit 200 executes image brightness correction. In addition, the data processing unit 200 performs various types of image processing and analysis processing on the image (fundus image, anterior eye image, etc.) obtained by the optical unit 2.

  The data processing unit 200 includes an analysis unit 210 and an eye refractive power value calculation unit 220. The analysis unit 210 analyzes the image obtained by the light field camera 21. The eye refractive power value calculation unit 220 analyzes the shape of the image depicted in the image of the eye E on which the measurement pattern light beam is projected by the measurement system 50 to obtain the eye refractive power value.

  As shown in FIG. 5, the analysis unit 210 includes a deconvolution processing unit 211, an image quality evaluation unit 212, a best image extraction unit 213, and a specification unit 214.

  The deconvolution processing unit 211 performs a known deconvolution process on the image data obtained by the light field camera 21. For example, the deconvolution processing unit 211 performs the following processing. First, the deconvolution processing unit 211 forms a plurality of stereo image groups by performing ray tracing processing or the like on the image data according to the image plane position in the Z direction designated by the main control unit 110 or the user. The deconvolution processing unit 211 obtains a parallax from the formed image group using a known algorithm, translates and superimposes the image group according to the obtained parallax, and averages the superimposed image group By performing the processing, an image corresponding to the image plane position is generated. The user can specify an image plane position using the user interface unit 300. The deconvolution processing unit 211 can generate an image corresponding to an arbitrary image plane position in the Z direction.

  The image quality evaluation unit 212 evaluates the image quality of the image generated by the deconvolution processing unit 211. The image quality evaluation unit 212 can obtain an evaluation value representing the image quality of the generated image, and can evaluate the image quality of the image based on the obtained evaluation value. The evaluation value includes, for example, a value corresponding to contrast and luminance unevenness. In this embodiment, the image quality evaluation unit 212 evaluates the image quality of the image based on the contrast of the generated image. For example, the image quality evaluation unit 212 obtains the luminance difference in the luminance distribution of the entire image generated by the deconvolution processing unit 211 or the luminance difference in the luminance distribution of the feature region in the image as an evaluation value, and uses the obtained evaluation value. Based on this, the image quality of the image is evaluated. The characteristic region may be a region including a position corresponding to a characteristic part (boundary of the characteristic part) of the eye E. The feature area may be a predetermined area in the image.

  The best image extraction unit 213 extracts the image with the highest image quality from the images generated by the deconvolution processing unit 211 based on the evaluation result by the image quality evaluation unit 212. For example, the best image extraction unit 213 has the best contrast as the highest quality image among the plurality of anterior ocular segment images corresponding to the plurality of image plane positions in the Z direction generated by the deconvolution processing unit 211. An image (an anterior segment image having the maximum luminance difference) is extracted.

  The analysis unit 210 can specify the image plane position corresponding to the anterior segment image extracted by the best image extraction unit 213, and can specify the movement target position of the coarse Z alignment based on the specified image plane position. It is.

  The specifying unit 214 analyzes the image generated by the deconvolution processing unit 211, thereby specifying a region corresponding to the characteristic part of the eye E drawn in the image. The specifying unit 214 can specify the region by analyzing the pixel value of the image. When the image is a luminance image, the specifying unit 214 specifies an image region (pixel) corresponding to a feature part based on the distribution of luminance values in the image. For example, when the characteristic part is the pupil center, the specifying unit 214 specifies an image region (pupil region) corresponding to the pupil of the eye E based on the distribution of pixel values (such as luminance values) of the image. In general, since the pupil is drawn with lower brightness than other parts, the pupil area can be specified by searching for the low brightness image area. At this time, the pupil region may be specified in consideration of the shape of the pupil. That is, the pupil region can be specified by searching for a substantially circular and low luminance image region. Next, the specifying unit 214 specifies the center position of the specified pupil region. Since the pupil is substantially circular as described above, the contour of the pupil region can be specified, the center position of this contour (approximate circle or approximate ellipse) can be specified, and this can be used as the pupil center. Further, the center of gravity of the pupil region may be obtained, and the center of gravity position may be used as the center of the pupil. Note that even when a feature position corresponding to another feature part is specified, it is possible to specify the feature position based on the distribution of pixel values of the image as described above. The specifying unit 214 may specify a region including a position of a reflected image based on reflected light from the cornea of alignment light projected by the XY alignment optical system 30 as a feature region.

  The eye refractive power value calculation unit 220 analyzes the shape of the image based on the return light from the eye E obtained by the measurement system 50. For example, when the measurement system 50 projects a ring-shaped light beam as a measurement pattern light beam on the eye to be examined, the imaging device or the light field camera 21 in the light receiving system of the measurement system 50 acquires an image in which a ring image is depicted. The eye refractive power value calculation unit 220 obtains the centroid position of the ring image from the luminance distribution in the obtained image, obtains the luminance distribution along a plurality of scanning directions extending radially from the centroid position, and uses the ring image from the luminance distribution. Is identified. Subsequently, the eye refractive power value calculation unit 220 obtains an approximate ellipse of the specified ring image, and substitutes the major axis and minor axis of the approximate ellipse into a known formula to obtain the spherical power, the astigmatic power, and the astigmatic axis angle. Ask. Alternatively, the eye refractive power value calculation unit 220 can obtain the eye refractive power parameter based on the deformation and displacement of the ring image with respect to the reference pattern.

  The data processing unit 200 that functions as described above includes, for example, a microprocessor, a RAM, a ROM, a hard disk drive, a circuit board, and the like. In a storage device such as a hard disk drive, a computer program for causing the microprocessor to execute the above functions is stored in advance.

(User interface part)
The user interface unit 300 includes an operation unit 310 and a display unit 320. The operation unit 310 includes the operation device of the arithmetic control unit described above. The operation unit 310 may include various buttons and keys provided on the housing of the ophthalmologic apparatus 1 or outside. The display unit 320 includes the display device of the arithmetic control unit described above. In addition, the display unit 320 may include various display devices such as a touch panel provided on the housing of the optical unit 2.

  Note that the operation unit 310 and the display unit 320 need not be configured as individual devices. For example, a device in which a display function and an operation function are integrated, such as a touch panel, can be used. In that case, the operation unit 310 includes the touch panel and a computer program. The operation content for the operation unit 310 is input to the control unit 100 as an electrical signal. Further, operations and information input may be performed using a graphical user interface (GUI) displayed on the display unit 320 and the operation unit 310.

  The optical system accommodated in the optical unit 2 is an example of the “optical system” according to the embodiment. The optical system driving unit 2A is an example of the “driving unit” according to the embodiment. The anterior segment image is an example of the “eye image to be examined” according to the embodiment. The Z direction is an example of the “optical axis direction of the anterior ocular segment observation system” according to the embodiment. The X direction and the Y direction are examples of the “direction intersecting the optical axis direction of the anterior ocular segment observation system” according to the embodiment. The XY alignment optical system 30 is an example of a “first alignment optical system” according to the embodiment. The Z alignment optical system 40 is an example of a “second alignment optical system” according to the embodiment.

[Operation example]
6 and 7 show an operation example of the ophthalmologic apparatus 1 according to the embodiment. 6 and 7 show the flow of the alignment operation performed before the measurement by the measurement system 50. FIG. In the following flow, it is assumed that the main control unit 110 controls the anterior segment illumination light source 11 and lights the anterior segment illumination light source 11 at least before the step S1 is performed.

(S1)
The main controller 110 controls the alignment index light source 31 to turn on the alignment index light source 31 as a light source for XY alignment. As described above, the alignment light output from the alignment index light source 31 is reflected by the beam splitter BS 1, passes through the opening of the diaphragm 23, passes through the beam splitter BS 2, and passes through the objective lens 24 and passes through the objective lens 24. Projected to the anterior segment Ea.

(S2)
Subsequently, the main control unit 110 controls the light field camera 21 to photograph the anterior eye portion Ea of the eye E to be examined which is illuminated with the illumination light from the anterior eye portion illumination light source 11 and onto which the alignment light is projected. Let it begin. Thereby, the light field camera 21 acquires image data of the anterior segment Ea.

(S3)
Subsequently, the main control unit 110 causes the deconvolution processing unit 211 to generate a single anterior segment image at a predetermined reference image plane position based on the image data obtained from the light field camera 21 in S2. The predetermined reference image plane position is an image plane position corresponding to a position away from the objective lens 24 by a predetermined distance, and is a position where the microlens array of the light field camera 21 is arranged. Thereby, the ophthalmologic apparatus 1 can acquire an anterior ocular segment image that is optically conjugate with the arrangement position of the microlens array of the light field camera 21.

(S4)
The main control unit 110 causes the analysis unit 210 to specify whether or not there is a bright spot image based on the Purkinje image of the alignment light irradiated in S1 in the single anterior segment image acquired in S3. The analysis unit 210 searches for a bright spot image based on the distribution of pixel values (luminance values) of the anterior segment image. The main control unit 110 determines that a bright spot image has been detected in the anterior segment image when the analysis unit 210 searches for a bright spot image, and when the analysis unit 210 does not search for a bright spot image, the anterior segment It is determined that no bright spot image has been detected in the image.

  When it is determined in S4 that no bright spot image has been detected (S4: N), the operation of the ophthalmologic apparatus 1 proceeds to S11. When it is determined that a bright spot image is detected in S4 (S4: Y), the operation of the ophthalmologic apparatus 1 proceeds to S5.

(S5)
When it is determined that a bright spot image is detected in S4 (S4: Y), the main control unit 110 controls the optical system driving unit 2A so as to cancel the displacement of the bright spot image with respect to a predetermined XY alignment reference position. Accordingly, the optical unit 2 and the eye E to be examined are relatively moved in the X direction and the Y direction (direction orthogonal to (intersects with) the optical axis of the anterior segment observation system 20) (precise XY alignment control).

(S6)
Subsequently, the main control unit 110 controls the light source 41 to turn on the light source 41 as a light source for Z alignment. The divergent light output from the light source 41 is reflected by the cornea of the eye E to be examined.

(S7)
The main control unit 110 detects the presence or absence of a Z alignment signal output from the line sensor 43. When the Z alignment signal is detected, the main control unit 110 determines that the divergent light output from the light source 41 is received by the line sensor 43. When the Z alignment signal is not detected, the main control unit 110 determines that the divergent light output from the light source 41 has not been received by the line sensor 43. When the Z alignment signal is detected (S7: Y), the operation of the ophthalmologic apparatus 1 proceeds to S8. When the Z alignment signal is not detected (S7: N), the operation of the ophthalmologic apparatus 1 proceeds to S11.

(S8)
When the Z alignment signal is detected in S7 (S7: Y), the main control unit 110 specifies the light receiving position of the reflected light in the line sensor 43 based on the Z alignment signal. The main control unit 110 moves the optical unit 2 and the eye E to be relatively moved in the Z direction by controlling the optical system driving unit 2A so as to cancel the displacement of the light receiving position with respect to the center position of the line sensor 43 ( Precision Z alignment control).

(S9)
The main control unit 110 determines whether or not the Z alignment has been completed. The main control unit 110 can determine that the alignment is complete when the difference between the distance between the eye E and the optical unit 2 and the working distance of the objective lens 24 is within a predetermined threshold. For example, the main control unit 110 obtains the difference between the distance between the eye E and the optical unit 2 and the working distance of the objective lens 24 using the control content for the optical system driving unit 2A. When it is determined that the Z alignment is completed (S9: Y), the operation of the ophthalmologic apparatus 1 proceeds to S10. When it is determined that the Z alignment is not completed (S9: N), the operation of the ophthalmologic apparatus 1 proceeds to S2.

(S10)
When it is determined that the Z alignment has been completed in S9 (S9: Y), the main control unit 110 controls the measurement system 50 to execute the reflex measurement. The measurement system 50 projects a measurement pattern light beam onto the eye E, and receives return light of the measurement pattern light beam from the fundus of the eye E. The main control unit 110 causes the eye refractive power value calculation unit 220 to analyze the shape of the image based on the return light of the measurement pattern light beam based on the light reception result by the measurement system 50, and calculates the eye refractive power value. This is the end of the operation of the ophthalmologic apparatus 1 (end).

(S11)
When the bright spot image is not detected in S4 (S4: N), or when the Z alignment signal is not detected in S7 (S7: N), the main control unit 110 uses the single front generated in S3. In the eye image, the specifying unit 214 specifies the pupil region (region including the center of the pupil) of the eye E to be examined. When the specifying unit 214 specifies the pupil region of the eye E in the anterior segment image (S11: Y), the operation of the ophthalmologic apparatus 1 proceeds to S16. When the pupil region of the eye E to be examined is not specified in the anterior segment image by the specifying unit 214 (S11: N), the operation of the ophthalmologic apparatus 1 proceeds to S12.

(S12)
When the pupil region of the eye E is not specified in the anterior segment image by the specifying unit 214 in S11 (S11: N), the main control unit 110 is based on the image data acquired by the light field camera 21 in S2. Then, the deconvolution processing unit 211 generates an anterior segment image at a plurality of image plane positions in the Z direction. The plurality of image plane positions may be determined in advance or may be designated by the user using the operation unit 310.

(S13)
Subsequently, the main control unit 110 causes the specifying unit 214 to specify the pupil region (region including the pupil center) of the eye E for each of the plurality of anterior segment images generated in S12. When the specifying unit 214 specifies the pupil region of the eye E in any one of the anterior segment images (S13: Y), the operation of the ophthalmologic apparatus 1 proceeds to S14. When the specifying unit 214 does not specify the pupil region of the eye E in all the anterior segment images (S13: N), the operation of the ophthalmologic apparatus 1 proceeds to S17.

(S14)
When the pupil region of the eye E is specified in any anterior segment image in S13 (S13: Y), the main control unit 110 moves the displacement target position of XY alignment and Z alignment (coarse Z alignment). Are specified by the analysis unit 210. The analysis unit 210 specifies the displacement of the XY alignment based on the displacement of the pupil center specified in S13 with respect to the predetermined XY alignment reference position.

  Further, the analysis unit 210 can specify the movement target position in the Z direction as follows.

  FIG. 8 illustrates an operation explanatory diagram of the analysis unit 210 according to the embodiment. In FIG. 8, the horizontal axis represents the position in the Z direction, and the vertical axis represents the contrast of the anterior segment image.

  The analysis unit 210 causes the image quality evaluation unit 212 to evaluate the image quality of the anterior segment image corresponding to the current position Z0 in the Z direction. In this embodiment, an evaluation value representing the contrast of the anterior segment image corresponding to the current position Z0 is obtained. In addition, the analysis unit 210 acquires an anterior ocular segment image corresponding to a position Z1 different from the current position Z0 from the multiple anterior ocular segment images generated in S12, and determines the image quality of the acquired anterior ocular segment image. The image quality evaluation unit 212 is evaluated. In this embodiment, an evaluation value representing the contrast of the anterior segment image corresponding to the position Z1 is obtained. When the analysis unit 210 determines that the contrast of the anterior ocular segment image corresponding to the position Z1 is better than the contrast of the anterior ocular segment image corresponding to the current position Z0 based on these evaluation values, the analysis unit 210 moves toward the position Z1. The position moved by a predetermined step is specified as the movement target position. When it is determined that the contrast of the anterior segment image corresponding to the position Z1 is worse than the contrast of the anterior segment image corresponding to the current position Z0, the analysis unit 210 has moved by a predetermined step in a direction away from the position Z1. The position is specified as the movement target position. As described above, the analysis unit 210 has an image plane position corresponding to the anterior ocular segment image having higher image quality than the anterior ocular segment image corresponding to the current relative position between the optical unit 2 and the eye E (supporting unit 440). Based on this, the movement target position can be obtained.

  Further, the analysis unit 210 may cause the image quality evaluation unit 212 to evaluate the image quality of each anterior segment image generated in S12. The main control unit 110 causes the best image extraction unit 213 to extract the highest image quality anterior segment image based on the evaluation result by the image quality evaluation unit 212. The best image extraction unit 213 extracts the anterior ocular segment image having the best contrast among the multiple anterior ocular segment images generated in S12 as the anterior ocular segment image with the highest image quality. The analysis unit 210 can specify the movement target position based on the image plane position corresponding to the anterior segment image extracted by the best image extraction unit 213.

(S15)
The main control unit 110 controls the optical system driving unit 2A so as to cancel the displacement of the XY alignment specified in S14 so that the optical unit 2 and the eye E to be examined are relative to at least one of the X direction and the Y direction. Move (coarse XY alignment control). In parallel with this, the main control unit 110 controls the optical system driving unit 2A based on the movement target position specified in S14 to relatively move the optical unit 2 and the eye E to be examined in the Z direction ( Coarse Z alignment control). Thereafter, the operation of the ophthalmologic apparatus 1 proceeds to S2.

(S16)
When the pupil region of the eye E is identified in the anterior segment image in S11 (S11: Y), the main control unit 110 executes pupil alignment (XY alignment). That is, the main control unit 110 controls the optical system drive unit 2A so as to cancel the displacement of the pupil center specified in S11 with respect to the predetermined XY alignment reference position, thereby controlling the optical unit 2 and the eye E to be examined. Relative movement is performed in at least one of the X direction and the Y direction (coarse XY alignment control). Thereafter, the operation of the ophthalmologic apparatus 1 proceeds to S2.

(S17)
When the pupil region of the eye E is not specified in all anterior segment images in S13 (S13: N), the main control unit 110 executes manual alignment. That is, the main control unit 110 displays the alignment reference position on the display unit 320, and controls the optical system driving unit 2A based on the operation content on the operation unit 310 by the user, thereby causing the optical unit 2 and the eye E to be examined. Move relative. For example, the user performs an operation of moving the optical system so as to guide the bright spot image to the alignment reference position displayed on the display unit 320. Thereafter, the operation of the ophthalmologic apparatus 1 proceeds to S2.

  As described above, according to the embodiment, since the optical system for fine alignment and the light field camera 21 are included and coarse alignment is performed using the light field camera 21, the optical unit has a wide dynamic range. 2 and the eye E can be aligned.

(Modification)
In the above embodiment, the case where the position in the Z direction is specified based on the image quality (contrast) of the image obtained by the deconvolution process has been described, but the configuration according to the embodiment is not limited to this. For example, the position in the Z direction may be specified based on the spot size of the bright spot image based on the reflected light of the alignment light projected on the eye E.

  Below, the ophthalmologic apparatus which concerns on the modification of embodiment is demonstrated centering on difference with the ophthalmologic apparatus 1 which concerns on embodiment.

  The configuration of the optical system of the ophthalmic apparatus according to the modification is the same as the configuration of the optical system of the ophthalmic apparatus 1 according to the embodiment. The configuration of the control system of the ophthalmologic apparatus according to the modification is different from the configuration of the control system of the ophthalmologic apparatus 1 according to the embodiment in that an analysis unit 210a is provided instead of the analysis unit 210.

  FIG. 9 shows a block diagram of a schematic configuration of the analysis unit 210a of the ophthalmologic apparatus according to the modification. 9, parts that are the same as those in FIG. 5 are given the same reference numerals, and descriptions thereof will be omitted as appropriate.

  The difference between the analysis unit 210a and the analysis unit 210 is that a spot size specifying unit 250 is provided instead of the image quality evaluation unit 212. The spot size specifying unit 250 is a spot size of a bright spot image based on a Purkinje image of alignment light projected onto the eye E by the XY alignment optical system 30 with respect to the anterior segment image generated by the deconvolution processing unit 211. Is identified. The spot size specifying unit 250 can specify the size of the bright spot image based on the distribution of pixel values (luminance values) of the anterior segment image. For example, the spot size specifying unit 250 specifies a pixel region having a luminance value equal to or higher than a predetermined threshold as a bright spot image in the anterior segment image, and sets the length or area of at least one of the X direction and the Y direction as the bright spot. Specify as the size of the image.

  The operation of the ophthalmologic apparatus according to the modified example is substantially the same as the operation of the ophthalmologic apparatus 1 according to the embodiment except for the following points. In this modification, for example, in S14 of FIG. The analysis unit 210a causes the spot size specifying unit 250 to specify the spot size of the bright spot image in the anterior segment image corresponding to the current position Z0 in the Z direction as an evaluation value. The analysis unit 210a acquires an anterior ocular segment image corresponding to a position Z1 different from the current position Z0 from the multiple anterior ocular segment images generated in S12, and the bright spot in the acquired anterior ocular segment image. The spot size specifying unit 250 is made to specify the spot size of the image as an evaluation value. Based on these evaluation values, the analysis unit 210a determines that the size of the bright spot image of the anterior segment image corresponding to the position Z1 is smaller than the size of the bright spot image of the anterior segment image corresponding to the current position Z0. At this time, the position moved by a predetermined step in the direction approaching the position Z1 is specified as the movement target position. The analysis unit 210a moves away from the position Z1 when it is determined that the size of the bright spot image of the anterior segment image corresponding to the position Z1 is larger than the size of the bright spot image of the anterior segment image corresponding to the current position Z0. The position moved by a predetermined step is specified as the movement target position.

  Further, the analysis unit 210a may cause the spot size specifying unit 250 to specify the spot size of the bright spot image for each of the anterior segment images generated in S12. The main control unit 110 causes the best image extraction unit 213 to extract the anterior segment image having the highest image quality based on the identification result by the spot size identification unit 250. The best image extraction unit 213 extracts the anterior ocular segment image having the smallest bright spot image size among the plurality of anterior ocular segment images generated in S12 as the highest image quality anterior ocular segment image. The analysis unit 210 can specify the image plane position corresponding to the anterior segment image extracted by the best image extraction unit 213 as the movement target position.

[effect]
The effect of the ophthalmologic apparatus according to the embodiment will be described.

  The ophthalmic apparatus according to the embodiment includes an illumination system (10), an optical system (optical unit 2), a support unit (440), a drive unit (optical system drive unit 2A), and an analysis unit (200, 200a). And a control unit (100). The illumination system irradiates the eye to be examined (E) with illumination light. The optical system includes an anterior ocular segment observation system (20) and a measurement system (50). The anterior ocular segment observation system guides light from the anterior ocular segment (Ea) of the eye to be examined, which is illuminated by the illumination system, to the light field camera (21). The measurement system is used for optically acquiring data of the eye to be examined. The support unit supports the face of the subject. The drive unit relatively moves the optical system and the support unit in the optical axis direction (Z direction) of the optical system. The analysis unit obtains the movement target position by analyzing the image data obtained by the light field camera. The control unit relatively moves the optical system and the support unit by controlling the drive unit based on the movement target position.

  According to such a configuration, since the optical system and the support unit that supports the face of the subject are moved relative to each other based on the image obtained by the light field camera, the optical system can be used with a wide dynamic range. A new technique for performing alignment with the eye to be examined can be provided.

  In the ophthalmologic apparatus according to the embodiment, the analysis unit generates two or more eye images to be examined corresponding to two or more image plane positions in the optical axis direction based on the image data, and the two or more generated eye images are generated. The movement target position may be obtained based on the image quality of the eye image to be examined.

  According to such a configuration, based on the image data obtained by the light field camera, the optimum image quality in the optical axis direction is determined from the image quality of the plurality of eye images corresponding to the plurality of image plane positions in the optical axis direction of the optical system. Since the movement target position is specified, the configuration of the ophthalmologic apparatus that can perform alignment in the optical axis direction with a wide dynamic range can be simplified.

  In the ophthalmologic apparatus according to the embodiment, the two or more eye images to be examined include eye images to be examined corresponding to the current relative positions of the optical system and the support unit, and the analysis unit has a subject corresponding to the current relative positions. The movement target position may be obtained based on the image plane position corresponding to the eye image to be examined having higher image quality than the eye examination image.

  According to such a configuration, since the optical system and the eye to be examined can be aligned in the optical axis direction based on the image quality of the eye image to be examined, it is possible to perform alignment in the optical axis direction with a wide dynamic range. The configuration of a simple ophthalmologic apparatus can be simplified.

  In the ophthalmologic apparatus according to the embodiment, the analysis unit may obtain the movement target position based on the image plane position corresponding to the eye image with the highest image quality among the two or more eye images to be examined.

  According to such a configuration, it is possible to provide an ophthalmologic apparatus capable of aligning the optical system and the eye to be examined in the optical axis direction with high accuracy without providing a dedicated optical system.

  In the ophthalmologic apparatus according to the embodiment, the drive unit moves the optical system and the support unit in a direction (XY direction) relatively intersecting the optical axis direction of the optical system, and the analysis unit is based on the image data. The feature region corresponding to the feature region of the eye to be examined is specified, and the control unit controls the drive unit based on the feature region to move the optical system and the support unit relative to each other in the direction intersecting the optical axis direction. May be.

  According to such a configuration, in addition to the above effects, an ophthalmologic apparatus capable of alignment in a direction intersecting the optical axis of the optical system based on image data obtained by a light field camera can be provided. It becomes like this.

  In the ophthalmologic apparatus according to the embodiment, the control unit may perform movement control in the direction intersecting the optical axis direction by the driving unit in parallel with movement control in the optical axis direction by the driving unit.

  According to such a configuration, it is possible to position the optical system and the eye to be measured with higher accuracy than when the movement control is performed separately in the optical axis direction and the intersecting direction.

  In the ophthalmologic apparatus according to the embodiment, the optical system may include a first alignment optical system (XY alignment optical system 30) and a second alignment optical system (Z alignment optical system 40). The first alignment optical system is arranged substantially coaxially with the optical path of the anterior ocular segment observation system, projects the first alignment light (alignment light) onto the eye to be examined, and receives the first reflected light of the first alignment light from the eye to be examined. Used to detect. The second alignment optical system projects second alignment light (diverging light) from the outside of the optical axis of the anterior ocular segment observation system to the eye to be detected, and detects the second reflected light of the second alignment light from the eye to be examined. Used. The control unit precisely moves the optical system and the support unit based on the movement target position, and then controls the drive unit based on at least one of the detection result of the first reflected light and the detection result of the second reflected light. Alignment control may be performed.

  According to such a configuration, after performing the alignment based on the image data obtained by the light field camera, the precision alignment using the first alignment optical system and the second alignment optical system is executed. High alignment accuracy can be realized.

  In the ophthalmologic apparatus according to the embodiment, the optical system may include a first alignment optical system (XY alignment optical system 30). The first alignment optical system is arranged substantially coaxially with the optical path of the anterior ocular segment observation system, projects the first alignment light (alignment light) onto the eye to be examined, and receives the first reflected light of the first alignment light from the eye to be examined. Used to detect. The analysis unit (210a) may obtain the size of the alignment bright spot image based on the first alignment light based on the image data, and may find the movement target position based on the obtained size.

  According to such a configuration, the optimum movement target position in the optical axis direction is specified from the spot size of the alignment bright spot image in the image generated from the image data obtained by the light field camera. It is possible to simplify the configuration of an ophthalmologic apparatus that can perform alignment in the optical axis direction with a wide dynamic range.

  In the ophthalmologic apparatus according to the embodiment, the analysis unit generates two or more eye images corresponding to two or more image plane positions in the optical axis direction based on the image data, and the two or more generated eye to be examined. The movement target position may be obtained based on the image plane position corresponding to the eye image to be examined that minimizes the size of the alignment bright spot image in the image.

  According to such a configuration, it is possible to provide an ophthalmologic apparatus capable of aligning the optical system and the eye to be examined in the optical axis direction with a wide dynamic range and high accuracy.

  Note that due to restrictions on the arrangement of the optical system, a sufficient NA cannot be secured in the anterior ocular segment observation system, and the depth of focus for securing the necessary alignment resolution may not be obtained. Even in such a case, an alignment optical system with a wide dynamic range (an alignment optical system using a light field camera) and an alignment optical system with a sufficient accuracy but a narrow dynamic range (an alignment optical system using an alignment bright spot image) ) In combination, it is possible to provide an ophthalmologic apparatus capable of alignment with sufficient accuracy over a wide range.

  In the ophthalmologic apparatus according to the embodiment, the optical system may include a second alignment optical system (Z alignment optical system 40). The second alignment optical system projects second alignment light (diverging light) from the outside of the optical axis of the anterior ocular segment observation system to the eye to be detected, and detects the second reflected light of the second alignment light from the eye to be examined. Used. The control unit moves the optical system and the support unit relative to each other based on the movement target position, and then controls the drive unit based on at least one of the detection result of the first reflected light and the detection result of the second reflected light. Precision alignment control may be performed.

  According to such a configuration, after performing the alignment based on the image data obtained by the light field camera, the precision alignment using the first alignment optical system and the second alignment optical system is executed. High alignment accuracy can be realized.

  The ophthalmologic apparatus according to the embodiment may include the above light field camera.

  According to such a configuration, it is possible to provide an ophthalmologic apparatus equipped with a light field camera and capable of aligning the optical system and the eye to be examined with a wide dynamic range.

  The configuration described above is merely an example for favorably implementing the present invention. Therefore, arbitrary modifications (omitted, replacement, addition, etc.) within the scope of the present invention can be made as appropriate. The configuration to be applied is selected according to the purpose, for example. In addition, depending on the configuration to be applied, a function and effect obvious to those skilled in the art and the function and effect described in this specification can be obtained.

  In addition, said embodiment is not limited to the structure of a light field camera, or the processing content of a deconvolution process. In the above-described embodiment, by performing deconvolution processing according to the configuration of the light field camera, an image whose focus is adjusted to one of a plurality of image plane positions in the optical axis direction of the anterior ocular segment observation system is acquired after shooting. You can apply what you can.

DESCRIPTION OF SYMBOLS 1 Ophthalmology apparatus 2 Optical unit 2A Optical system drive part 10 Illumination system 11 Anterior eye part illumination light source 20 Anterior eye part observation system 21 Light field camera 22 Relay lens 23 Diaphragm 24 Objective lens 30 XY alignment optical system 31 Alignment index light source 32 Lens 40 Z alignment optical system 41 Light source 42 Condensing lens 43 Line sensor 50 Measurement system 100 Control unit 110 Main control unit 120 Storage unit 200 Data processing unit 210 Analysis unit 211 Deconvolution processing unit 212 Image quality evaluation unit 213 Best image extraction unit 214 Identification unit 220 Eye refractive power value calculation unit 300 User interface unit 310 Operation unit 320 Display unit 410 Base 420 Case 430 Lens housing unit 440 Support unit BS1, BS2 Beam splitter E Eye to be examined Ea Anterior segment

Claims (11)

An illumination system for irradiating the eye with illumination light;
An anterior ocular segment observation system that guides light from the anterior ocular segment of the subject eye irradiated with the illumination light by the illumination system to a light field camera, and a measurement system for optically acquiring data of the subject eye An optical system with
A support part for supporting the face of the subject;
A drive unit that relatively moves the optical system and the support unit in an optical axis direction of the optical system;
An analysis unit for obtaining a movement target position by analyzing image data obtained by the light field camera;
A control unit that relatively moves the optical system and the support unit by controlling the drive unit based on the movement target position;
Ophthalmic device. The analysis unit generates two or more eye images corresponding to two or more image plane positions in the optical axis direction based on the image data, and based on the image quality of the generated two or more eye images generated. The ophthalmologic apparatus according to claim 1, wherein the movement target position is obtained. The two or more test eye images include a test eye image corresponding to a current relative position between the optical system and the support unit,
The ophthalmologic according to claim 2, wherein the analysis unit obtains the movement target position based on an image plane position corresponding to an eye image to be examined having higher image quality than an eye image to be examined corresponding to the current relative position. apparatus. The said analysis part calculates | requires the said movement target position based on the image surface position corresponding to the to-be-examined eye image of the highest image quality among the said 2 or more to-be-examined eye images. Ophthalmic equipment. The drive unit moves the optical system and the support unit relatively in a direction intersecting the optical axis direction of the optical system,
The analysis unit identifies a feature region corresponding to a feature part of the eye to be examined based on the image data,
The said control part controls the said drive part based on the said characteristic area, and moves the said optical system and the said support part relatively in the direction which cross | intersects the said optical axis direction. The ophthalmic apparatus according to claim 4. The ophthalmologic according to claim 5, wherein the control unit performs movement control in a direction intersecting the optical axis direction by the driving unit in parallel with movement control in the optical axis direction by the driving unit. apparatus. The optical system is
A first alignment is arranged substantially coaxially with the optical path of the anterior ocular segment observation system, projects first alignment light onto the eye to be examined, and detects first reflected light of the first alignment light from the eye to be examined. Optical system,
A second alignment optical system for projecting second alignment light to the eye to be examined from outside the optical axis of the anterior ocular segment observation system, and detecting second reflected light of the second alignment light from the eye to be examined;
Including
The control unit moves the optical system and the support unit relative to each other based on the movement target position, and then based on at least one of the detection result of the first reflected light and the detection result of the second reflected light. The ophthalmic apparatus according to claim 5, wherein fine alignment control for controlling the driving unit is performed. The optical system is disposed substantially coaxially with the optical path of the anterior ocular segment observation system, projects first alignment light onto the eye to be examined, and detects first reflected light of the first alignment light from the eye to be examined. A first alignment optical system for
The said analysis part calculates | requires the size of the alignment bright spot image based on the said 1st alignment light based on the said image data, and calculates | requires the said movement target position based on the calculated | required size. The ophthalmologic apparatus according to claim 6. The analysis unit generates two or more eye images corresponding to two or more image plane positions in the optical axis direction based on the image data, and the alignment brightness among the generated two or more eye images to be examined. The ophthalmologic apparatus according to claim 8, wherein the movement target position is obtained based on an image plane position corresponding to an eye image to be examined with a point image having a minimum size. The optical system projects second alignment light onto the eye to be examined from outside the optical axis of the anterior ocular segment observation system, and detects second reflected light of the second alignment light from the eye to be examined. Including alignment optics,
The control unit moves the optical system and the support unit relative to each other based on the movement target position, and then based on at least one of the detection result of the first reflected light and the detection result of the second reflected light. The ophthalmic apparatus according to claim 8 or 9, wherein precise alignment control for controlling the driving unit is performed. The ophthalmologic apparatus according to claim 1, comprising the light field camera.

Images