JP2018158913A - Visceral fat accumulation inhibitor - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide visceral fat accumulation inhibitors or compositions containing chia seed sprouts, safe in eating habits, as an active ingredient.SOLUTION: The present invention provides visceral fat accumulation inhibitors and compositions containing chia seed sprouts as an active ingredient. The present invention further provides pharmaceuticals for preventing or improving visceral fat accumulation, functional food and drink, food and drink material, cosmetics and feed, containing the visceral fat accumulation inhibitors and compositions.SELECTED DRAWING: Figure 1

Description

  The present invention relates to a composition for the purpose of suppressing visceral fat accumulation, and a food, drink, pharmaceutical or feed containing the composition.

  The term metabolic syndrome is generally widespread, but there is still a need for countermeasures for its prevention and improvement. Although it has been clarified that correction of lifestyle habits is important and effective for prevention and improvement of metabolic syndrome, it is difficult to change lifestyle habits, and the current situation is that the number of people with metabolic syndrome will not decrease. As one of the methods for improving the current situation, effective use of functional foods and supplements has attracted attention, and a search for new food materials having an action of suppressing visceral fat accumulation has been demanded.

  Chia seed is an annual plant of the family Lamiaceae, which is a seed of chia (scientific name: Salvia hispanica) cultivated mainly in South America and Australia. Chia seeds are edible and are attracting attention as superfoods because they contain abundant n-3 fatty acids. We focused on chia seed shoots (hereinafter called chia sprout). Chia sprout is an ingredient that is easy to eat as raw foods such as salads without strawberry, but its functionality is unknown, and the visceral fat accumulation inhibitory effect has not yet been reported.

  An object of the present invention is to provide a composition having a visceral fat accumulation-inhibiting action, and thus to provide a pharmaceutical, a functional food, a food, a food, a cosmetic or a feed containing the composition.

As a result of intensive studies to solve the above problems, it was found that thiaprout has a remarkable visceral fat accumulation inhibitory action. That is, the present invention has the following configuration.
(1) A visceral fat accumulation inhibitor characterized by containing a component of thiaprout.
(2) A pharmaceutical, functional food / beverage product, food / beverage product, cosmetic product or feed containing the composition according to (1) above.

  According to the present invention, it is possible to provide a visceral fat accumulation inhibitor containing thia sprout components, and pharmaceuticals, functional foods and drinks, foods and drinks, cosmetics or feeds containing the composition.

  The chia sprout according to the present invention is a sprout cultivated to about 5 cm by hydroponically cultivating chia seeds, and may be used as a raw food or may be used as a dry powder.

In order to produce the visceral fat accumulation-inhibiting agent according to the present invention, the components of thiaprout produced by the above-described method can be used, and may be formulated in combination with a known non-toxic pharmaceutical carrier according to a conventional method. The fat absorption inhibitor according to the present invention can be administered in various dosage forms. For example, oral administration includes solid agents such as tablets, granules, powders, capsules, soft capsules, solutions, suspensions, and the like. Examples thereof include suspensions, liquids such as emulsifiers, freeze-drying agents and the like, and these preparations can be prepared by conventional means in preparation. Examples of the non-toxic pharmaceutical carrier include glucose, lactose, sucrose, starch, mannitol, dextrin, fatty acid glyceride, polyethylene glycol, hydroxyethyl starch, ethylene glycol, polyoxyethylene sorbitan fatty acid ester, amino acid, albumin, water, Examples thereof include physiological saline. In addition, conventional additives such as stabilizers, lubricants, wetting agents, emulsifiers, binders and the like can be appropriately added as necessary. The dose of the visceral fat accumulation-inhibiting component in the visceral fat accumulation-inhibiting agent according to the present invention is appropriately selected and determined according to the patient's age, weight, symptoms, disease level, administration schedule, formulation form, etc. The dry weight of chia sprout per day is about 0.001 mg ^to 1000 mg / kg body weight, and may be divided into several times a day.

Moreover, since it has not been reported that thiaprout has toxicity, it can be taken as a food or drink for the purpose of suppressing visceral fat accumulation. The component of the chia sprout can be positioned as a food for specified health use, a nutritional functional food, a health food, or the like. As functional foods, for example, after adding a suitable auxiliary agent to the ingredients of chia sprout, using conventional means, it is in an edible state, for example, granules, granules, tablets, capsules, soft capsules, What was formed in the paste form etc. can be used. This food and drink may be used for food as it is, and added to various foods (for example, ham, sausage, kamaboko, chikuwa, bread, butter, milk powder, confectionery, etc.), water, alcoholic beverages, fruit juice, It may be used by adding to drinks such as milk and soft drinks. The intake amount of the components of the chia sprout of the present invention in such a food form is appropriately selected and determined according to age, body weight, symptom, degree of disease, food form, etc. The dose is about 001 mg ^to 1000 mg / kg body weight, and may be administered in several divided doses a day.

  Examples are given below to describe the present invention in more detail, but the present invention is not limited by these.

  Example Inhibitory Effect of Chia Sprout on Visceral Fat Accumulation In order to examine the inhibitory effect of chia sprout on visceral fat accumulation, the following experiment was conducted. That is, ICR mice (male) were divided into two groups after one week of preliminary breeding, and were fed with a standard diet (AIN-93M) and a thia sprout powder mixed standard diet, respectively. The animals were reared for 8 weeks and their body weights were measured (drawing A). In addition, the testicular fat weight and perirenal fat weight were measured on the last day of breeding (Drawing B). Numerical values are shown as mean ± standard error, and * indicates a significant difference between the thiaprout group and the control (student T-test, p <0.05).

  This result showed that thiaprout suppresses visceral fat accumulation.

  INDUSTRIAL APPLICABILITY According to the present invention, it is possible to provide a visceral fat accumulation-suppressing composition containing a component of thiaprout and a pharmaceutical, functional food, drink, food, cosmetic or feed containing the composition. It was.

Claims (7)

A visceral fat accumulation inhibitor containing thiaprout as an active ingredient. A visceral fat accumulation inhibitor containing a composition containing thiaprout as an active ingredient. [1] A pharmaceutical product comprising the visceral fat accumulation inhibitor described in [2]. A functional food or drink comprising the visceral fat accumulation inhibitor according to [1] to [2]. A food and drink material comprising the visceral fat accumulation inhibitor according to [1] to [2]. [1] A feed containing the visceral fat accumulation inhibitor according to [2]. Cosmetics containing the visceral fat accumulation inhibitor according to [1] to [2].

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