JP2018118936A5 - - Google Patents

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Publication number
JP2018118936A5
JP2018118936A5 JP2017012594A JP2017012594A JP2018118936A5 JP 2018118936 A5 JP2018118936 A5 JP 2018118936A5 JP 2017012594 A JP2017012594 A JP 2017012594A JP 2017012594 A JP2017012594 A JP 2017012594A JP 2018118936 A5 JP2018118936 A5 JP 2018118936A5
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Japan
Prior art keywords
polyethylene glycol
enteric
solid preparation
layer
granule
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JP2017012594A
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Japanese (ja)
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JP7064683B2 (en
JP2018118936A (en
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Priority to JP2017012594A priority Critical patent/JP7064683B2/en
Priority claimed from JP2017012594A external-priority patent/JP7064683B2/en
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Publication of JP2018118936A5 publication Critical patent/JP2018118936A5/ja
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Claims (8)

Ｄ-マンニトール及びポリエチレングリコールを含む、腸溶層の破損防止用組成物。   A composition for preventing damage to an enteric layer, comprising D-mannitol and polyethylene glycol. Ｄ-マンニトール及びポリエチレングリコールの比が、１０：１〜１：１である請求項１記載の組成物。   The composition according to claim 1, wherein the ratio of D-mannitol and polyethylene glycol is from 10: 1 to 1: 1. ポリエチレングリコールが、ポリエチレングリコール４００、ポリエチレングリコール４０００、ポリエチレングリコール６０００から選択される１種又は２種以上である請求項１又は２記載の組成物。   The composition according to claim 1 or 2, wherein the polyethylene glycol is one or more selected from polyethylene glycol 400, polyethylene glycol 4000, and polyethylene glycol 6000. 多層構造を有する腸溶性顆粒において、腸溶層及び／又は腸溶層より外側にある層を請求項１〜３のいずれか１項記載の組成物で被覆することを特徴とする腸溶性顆粒。 An enteric granule having a multilayer structure, wherein the enteric layer and / or a layer outside the enteric layer is coated with the composition according to any one of claims 1 to 3. 腸溶性顆粒に含まれる主薬成分が、プロトンポンプ阻害薬である請求項４記載の腸溶性顆粒。   The enteric granule according to claim 4, wherein the main drug component contained in the enteric granule is a proton pump inhibitor. 請求項４又は５記載の腸溶性顆粒を含有する固形製剤。 A solid preparation comprising the enteric granules according to claim 4. 錠剤である請求項６記載の固形製剤。 The solid preparation according to claim 6, which is a tablet. 口腔内崩壊錠である請求項６記載の固形製剤。 The solid preparation according to claim 6, which is an orally disintegrating tablet.
JP2017012594A 2017-01-27 2017-01-27 Composition for preventing damage to the enteric layer Active JP7064683B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2017012594A JP7064683B2 (en) 2017-01-27 2017-01-27 Composition for preventing damage to the enteric layer

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2017012594A JP7064683B2 (en) 2017-01-27 2017-01-27 Composition for preventing damage to the enteric layer

Publications (3)

Publication Number Publication Date
JP2018118936A JP2018118936A (en) 2018-08-02
JP2018118936A5 true JP2018118936A5 (en) 2020-03-05
JP7064683B2 JP7064683B2 (en) 2022-05-11

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JP2017012594A Active JP7064683B2 (en) 2017-01-27 2017-01-27 Composition for preventing damage to the enteric layer

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Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2020055755A (en) * 2018-09-28 2020-04-09 日本ケミファ株式会社 Enteric preparation
WO2020218517A1 (en) * 2019-04-25 2020-10-29 富士製薬工業株式会社 Medicinal preparation and method for manufacturing same
JP2021046372A (en) * 2019-09-19 2021-03-25 日医工株式会社 Esomeprazole-containing preparation
US20230058473A1 (en) * 2020-01-27 2023-02-23 Towa Pharmaceutical Co., Ltd. Esomeprazole oral preparation and method for producing the same

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2587022A1 (en) * 1998-05-18 1999-11-25 Takeda Pharmaceutical Company Limited Orally disintegrable tablets
US6749867B2 (en) * 2000-11-29 2004-06-15 Joseph R. Robinson Delivery system for omeprazole and its salts
EP1596838A2 (en) * 2003-02-11 2005-11-23 Torrent Pharmaceuticals Ltd Once a day orally administered pharmaceutical compositions comprising a proton pump inhibitor and a prokinetic agent
CN1263450C (en) * 2005-01-20 2006-07-12 北京科信必成医药科技发展有限公司 Disintegration piece of omeprazole and ramification taken through oral cavity and jpreparing technique
CN101646421A (en) * 2007-04-26 2010-02-10 卫材R&D管理有限公司 The preparation method of tablet
WO2008140459A1 (en) * 2007-05-16 2008-11-20 Fmc Corporation Solid form
EP2044932A1 (en) * 2007-10-04 2009-04-08 Laboratorios del Dr. Esteve S.A. Mechanical protective layer for solid dosage forms

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