JP2018108064A5

JP2018108064A5 -

Info

Publication number: JP2018108064A5
Application number: JP2017000814A
Authority: JP
Filing date: 2017-01-06
Publication date: 2020-02-06
Anticipated expiration: 2037-01-06

Description

上記態様においては、前記表示部が、前記統計解析結果として、各前記継代周期内における前記細胞の増殖曲線を表示することとしてもよい。
継代を繰り返すことにより細胞が劣化して増殖能力が低下してくると、増殖曲線の上昇カーブが緩やかになる。このように構成することで、表示部に表示される増殖曲線の傾きにより、各継代周期の細胞の増殖能力の変化を一見して把握することができる。 In the above embodiments, the display unit, as the statistical analysis result may be displayed intensifying殖曲lines of the cells in each said passage period.
When the cells are deteriorated due to repeated passages and the growth ability is reduced, the rising curve of the growth curve becomes gentle. With such a configuration, it is possible to grasp at a glance the change in the proliferation ability of the cells in each passage cycle by the slope of the proliferation curve displayed on the display unit.

上記態様においては、前記継代周期における前記細胞の増殖率に基づいて、前記細胞の品質を評価する品質評価部を備えることとしてもよい。
このように構成することで、品質評価部により、所望の品質を有する継代周期の細胞と所望の品質を有しない継代周期の細胞とに簡易に分けることができる。
上記態様においては、前記表示部が、複数の前記継代周期の前記増殖曲線を時間軸に沿って直列に表示することとしてもよい。 In the above aspect, a quality evaluation unit that evaluates the quality of the cell based on the proliferation rate of the cell in the passage cycle may be provided.
With such a configuration, the quality evaluation unit can easily divide the cells into cells having the desired quality in the passage cycle and cells having the desired quality in the passage cycle.
In the above aspect, the display unit may display the growth curves of the plurality of passage cycles in series along a time axis.

Claims

An image acquisition unit that acquires an image in a culture vessel for culturing cells over time,
Based on each of the images acquired by the image acquisition unit, an image analysis unit that quantitatively analyzes the culture state of the cells cultured in the culture container,
A statistical analysis unit for statistically analyzing the data analyzed by the image analysis unit,
A display unit for displaying the results of statistical analysis in the culture vessel in a plurality of passage cycles obtained by the statistical analysis unit in a comparable manner.

The display unit, the cell observation system according to claim 1 as the statistical analysis result, to display the increase殖曲lines of the cells in each said passage period.

The cell observation system according to claim 2, wherein the display unit displays the growth curves of the plurality of passage cycles in a superimposed manner.

The cell observation system according to any one of claims 1 to 3, further comprising a comparison unit configured to compare a temporal change in the number of the cells for each of the passage cycles and output a change in the proliferation rate of the cells.

The cell observation system according to any one of claims 1 to 4, further comprising a quality evaluation unit that evaluates the quality of the cell based on a growth rate of the cell in the passage cycle.

The cell observation system according to claim 2, wherein the display unit displays the growth curves of the plurality of passage cycles in series along a time axis.