JP2018104319A - Hair growth composition - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide a hair growth composition in which white turbidness is inhibited.SOLUTION: A hair growth composition contains (A): Scutellaria root extract, (B): zinc compound, and (C): diester of cyclohexanedicarboxylic acid, and polyoxyethylene monoalkyl ether represented by general formula (1): R-(OCHCH)-OH (1) [where R is a C1-12 alkyl group, n is an integer of 2-11].SELECTED DRAWING: None

Description

  The present invention relates to a hair growth composition.

  Various ingredients such as a peripheral vasodilator, a hair root activator, an anti-inflammatory agent, a sebum secretion inhibitor, and a plant extract are used as active ingredients in the hair growth composition.

  For example, Patent Document 1 proposes a hair-growth composition containing a plant extract such as ougon extract.

Japanese Patent Laid-Open No. 5-97631

  In view of the above-described conventional techniques, the present inventors have developed a hair-growth composition containing an orgon extract, and in addition to the orgon extract, a compound containing a zinc compound as an ingredient for improving the firmness and stiffness of hair. Faced with the problem of white turbidity in the hair growth composition.

  The present invention has been made in view of the above-described problems, and an object of the present invention is to provide a hair-growth composition containing a urgonum extract and a zinc compound, which is suppressed in cloudiness.

  As a result of intensive studies to solve the above-mentioned problems, the present inventors have surprisingly found that the whitening of the composition for hair growth can be achieved by adding a specific diester described later in addition to the ougon extract and the zinc compound. It was found that it can be suppressed. The inventors of the present invention have completed the present invention by repeating further research based on such knowledge.

That is, the present invention includes the hair growth composition described in the following section.
Item 1.
(A): Ougon extract,
(B): a zinc compound, and (C): cyclohexanedicarboxylic acid,
General formula (1):
R— (OCH ₂ CH ₂ ) _n —OH (1)
[In general formula (1), R shows a C1-C12 alkyl group, n shows the integer of 2-11. ]
The composition for hair growth containing the diester with the polyoxyethylene monoalkyl ether represented by these.
Item 2.
Item 2. The hair growth composition according to Item 1, wherein a mass ratio of the C component to the B component (C component / B component) is greater than 3.
Item 3.
The zinc compound is zinc gluconate, zinc chloride, zinc undecylenate, zinc stearate, zinc paraphenolsulfonate, zinc palmitate, zinc myristate, zinc laurate, basic zinc carbonate, zinc sulfate, zinc oxide, and Item 3. The hair growth composition according to Item 1 or 2, which is at least one selected from the group consisting of low-temperature fired zinc oxide.
Item 4.
Item 4. The hair growth composition according to any one of Items 1 to 3, wherein the cyclohexanedicarboxylic acid is 1,4-cyclohexanedicarboxylic acid.
Item 5.
Item 5. The hair growth composition according to any one of Items 1 to 4, wherein the polyoxyethylene monoalkyl ether is diethylene glycol monoethyl ether.
Item 6.
Item 5. The hair growth composition according to any one of Items 1 to 5, comprising 0.1 to 10% by mass of the component B and 0.1 to 10% by mass of the component C.
Item 7.
Item 7. The hair growth composition according to any one of Items 1 to 6, comprising 0.1 to 10% by mass of the component A.

  ADVANTAGE OF THE INVENTION According to this invention, the composition for hair growth which has the outstanding external appearance property by which white turbidity was suppressed can be provided.

It is a photograph which shows the result of a test example. In FIG. 1, it corresponds to Examples 1 to 6 and Comparative Examples 1 to 5 in order from the left.

  Hereinafter, the present invention will be described in detail.

The present invention includes a hair growth composition. The hair growth composition of the present invention comprises:
(A) Ogon extract,
(B) zinc compound and (C) cyclohexanedicarboxylic acid, and general formula (1):
R— (OCH ₂ CH ₂ ) _n —OH (1)
[In general formula (1), R shows a C1-C12 alkyl group, n shows the integer of 2-11. ]
The diester with the polyoxyethylene monoalkyl ether represented by these is included.

  In addition, in this specification, a diester of a polyoxyethylene monoalkyl ether represented by “O component”, “Z component”, zinc compound “B component”, and cyclohexanedicarboxylic acid represented by the general formula (1) is simply “ Sometimes referred to as “diester” or “C component”.

  Ogon extract, which is the component A, is an extract of Ogon, which is the root of Scutella nigra, and has a hair-growing / hair-growing action. The method for producing ougon extract is not particularly limited, and can be produced by a known method. Further, the extraction solvent is not particularly limited, and for example, a known solvent used for normal extraction such as water, alcohol, ether, chloroform and the like can be used. Moreover, a commercial item can be used as an ougon extract.

  The content of Ogon extract contained in the hair restoring composition of the present invention is not particularly limited as long as it is within a range in which the hair restoring action is exhibited. For example, the content is based on the whole hair restoring composition of the present invention (100% by mass). As about 0.1-10 mass%, Preferably it is about 1-10 mass%, More preferably, it is about 2-9 mass%, More preferably, it is about 2-8 mass%, More preferably, it is about 2-7 mass%, Especially preferably, it is about 3-6 mass%, Most preferably, it is about 4-5 mass%.

  The zinc compound as component B has an action of imparting firmness and stiffness to the hair. As a zinc compound, if it is a zinc compound which can be mix | blended with the composition for hair growth, it will not specifically limit, A well-known zinc compound can be used. For example, zinc gluconate, zinc chloride, zinc undecylenate, zinc stearate, zinc paraphenolsulfonate, zinc palmitate, zinc myristate, zinc laurate, basic zinc carbonate, zinc sulfate, zinc oxide, and low temperature firing oxidation Examples include zinc. Among these, zinc gluconate is preferable. Moreover, a zinc compound may be used individually by 1 type, and 2 or more types may be mixed and used for it. When mixing and using 2 or more types, the mixing ratio in particular is not restrict | limited, It can determine suitably.

  The content of the zinc compound contained in the hair growth composition of the present invention is not particularly limited as long as it has an effect of imparting firmness and stiffness to the hair. For example, the whole hair growth composition of the present invention As a reference (100% by mass), about 0.1 to 10% by mass, preferably about 0.1 to 5% by mass, more preferably about 0.1 to 4% by mass, and still more preferably 0.1 to 3% by mass. %, More preferably about 0.1 to 2% by weight, particularly preferably about 0.1 to 1% by weight, and most preferably about 0.1 to 0.75% by weight.

The diester as component C is cyclohexanedicarboxylic acid and general formula (1):
R— (OCH ₂ CH ₂ ) _n —OH (1)
[In general formula (1), R shows a C1-C12 alkyl group, n shows the integer of 2-11. ]
It is a diester with the polyoxyethylene monoalkyl ether represented by these.

  The diester is an ester oil agent having both hydrophilic and lipophilic functions, and has an action of promoting penetration of an active ingredient into hair and skin. Further, although not intended to be limited, the use of the diester can suppress the cloudiness of the composition containing the ougon extract and the zinc compound.

  The cyclohexanedicarboxylic acid constituting the diester is not particularly limited, and examples thereof include 1,2-cyclohexanedicarboxylic acid, 1,3-cyclohexanedicarboxylic acid, 1,4-cyclohexanedicarboxylic acid, and the like. Of these, 1,4-cyclohexanedicarboxylic acid is preferable. Cyclohexanedicarboxylic acid has cis and trans isomers. Cyclohexanedicarboxylic acid constituting the diester is any of cis, trans, or a mixture of cis and trans. Also good.

  The polyoxyethylene monoalkyl ether constituting the diester is a compound represented by the general formula (1). In general formula (1), R shows a C1-C12 alkyl group, n shows the integer of 2-11.

  The alkyl group having 1 to 12 carbon atoms represented by R may be linear, branched or cyclic, and is preferably linear or branched. For example, methyl group, ethyl group, propyl group, isopropyl group, n-butyl group, sec-butyl group, tert-butyl group, isobutyl group, n-pentyl group, n-hexyl group, n-octyl group, n-decyl Group, n-dodecyl group and the like. Among these, R is preferably a methyl group or an ethyl group.

  n is an integer of 2 to 11, preferably an integer of 2 to 9, more preferably an integer of 2 to 7, still more preferably an integer of 2 to 5. Or 3 is particularly preferred.

  Examples of the polyoxyethylene monoalkyl ether represented by the general formula (1) include diethylene glycol monoethyl ether and triethylene glycol monoethyl ether. Of these, diethylene glycol monoethyl ether is preferable.

  The production method of the diester is not particularly limited as long as it is a method in which cyclohexanedicarboxylic acid and the polyoxyethylene monoalkyl ether represented by the general formula (1) are esterified, and a known method can be adopted. For example, it can be produced by the method described in JP2008-127342A. Moreover, a commercial item can be used for diester.

  The content of the diester contained in the hair growth composition of the present invention is not particularly limited as long as the action of promoting the penetration of the active ingredient into the hair and skin is exerted. For example, the hair growth composition of the present invention Based on the total composition (100% by mass), about 0.1 to 10% by mass, preferably about 0.1 to 9% by mass, more preferably about 0.1 to 8% by mass, and still more preferably 0.1 About 7% by mass, more preferably about 0.1-6% by mass, particularly preferably about 0.25-5% by mass, and most preferably about 0.5-5% by mass.

  Further, in the hair growth composition of the present invention, the mass ratio (C component / B component) of the diester that is the C component to the zinc compound that is the B component is preferably greater than 3 and greater than 3 and 20 or less. More preferably, it is more than 3 and more preferably 15 or less, further preferably 4 or more and 15 or less, and particularly preferably 5 or more and 15 or less. Although a limited interpretation is not desired, when the mass ratio of the C component to the B component is within the above-described range, white turbidity of the hair growth composition of the present invention can be further suppressed.

  The hair-restoring composition of the present invention can usually contain components that can be blended in the hair-restoring composition, as long as the effects of the present invention are not impaired, in addition to the A component, the B component, and the C component described above. For example, hair-growth ingredients other than ougon extract, surfactants, greasing agents, moisturizers, polymers, UV absorbers, sequestering agents, solvents, pH adjusters, vitamins, antioxidants, antioxidant aids, Examples include antiseptics, fragrances, and refreshing agents. These components can be used alone or in combination of two or more. Moreover, content of these components in the composition for hair growth of this invention is not specifically limited, According to the compounding purpose of the said component, it can determine suitably.

  As a hair-growth component other than ougon extract, any known component can be used as long as it has a hair-growth effect. For example, peripheral vasodilators, hair root activators, anti-inflammatory agents, sebum secretion inhibitors and the like can be mentioned.

  Examples of the peripheral vasodilator include carpronium chloride, nicotinic acid derivatives (for example, benzyl nicotinate, nicotinic acid amide, dl-α-tocopherol nicotinate), vitamin E derivatives (for example, dl-α-tocopherol, d- α-tocopherol, dl-α-tocopherol acetate, etc.), acetylcholine, diphenhydramine hydrochloride, garlic iodide extract, spironolactone, γ-oryzanol, cephalanthin, nicorandil, minoxidil, diisopropylamine dichloroacetate, assembly extract, carrot extract, ginkgo extract, quina extract , Spruce extract, sophora extract and the like.

  Examples of hair root activators include mononitroguaiacol sodium, placenta extract, N-acetyl-L-methionine, adenosine, adenine, adenosine triphosphate disodium, cephalanthin, potassium aspartate, pentadecanoic acid glyceride, pantothenic acid, pantothenic acid Examples include ethyl, panthenol, yeast extract, garlic extract, royal jelly and the like.

  Examples of the anti-inflammatory agent include glycyrrhizic acid derivatives (such as dipotassium glycyrrhizinate and ammonium glycyrrhizinate), hydrocortisone acetate, azulene, guaiazulene, prednisolone, chamomile extract, kumazasa extract, and birch extract.

  Examples of the sebum secretion inhibitor include resorcin, pyridoxine hydrochloride, estradiol, and the like.

  Examples of the surfactant include an anionic surfactant, a cationic surfactant, an amphoteric surfactant, a lipophilic nonionic surfactant, and a hydrophilic nonionic surfactant.

  Examples of the anionic surfactant include higher alkyl sulfates such as sodium lauryl sulfate and potassium lauryl sulfate, alkyl ether sulfates such as POE-lauryl sulfate triethanolamine, POE-sodium lauryl sulfate, and lauroyl sarcosine sodium. Higher fatty acid amide sulfonates such as N-acyl sarcosine acid, sodium N-myristoyl-N-methyl taurate, coconut oil fatty acid methyl tauride sodium, sodium lauryl methyl tauride, POE oleyl ether sodium phosphate, POE stearyl ether phosphoric acid Phosphate ester salts such as sodium di-2-ethylhexylsulfosuccinate, monolauroyl monoethanolamide sodium polyoxyethylenesulfosuccinate, lauryl poly Sulfosuccinates such as sodium propylene glycol sulfosuccinate, sodium lineardodecylbenzenesulfonate, lineardodecylbenzenesulfonate triethanolamine, alkylbenzenesulfonates such as dodecylbenzenesulfonate, monosodium N-lauroylglutamate, di-N-stearoylglutamate N-acylglutamate such as sodium, monosodium N-myristoyl-L-glutamate, higher fatty acid ester sulfate such as sodium glyceryl sulfate hardened coconut oil fatty acid, POE-alkyl ether carboxylic acid, POE-alkyl allyl ether carboxylate , Α-olefin sulfonate, higher fatty acid ester sulfonate, secondary alcohol sulfate, higher fatty acid alkylolamide sulfate Examples include ester salts, sodium lauroyl monoethanolamide succinate, ditriethanolamine N-palmitoyl aspartate, sodium caseinate and the like.

  Examples of the cationic surfactant include quaternary ammonium salt type cationic surfactants, poly (N, N′-dimethyl-3,5-methylenepiperidinium chloride), alkylisoquinolinium salts, dialkylmoris. Examples thereof include phonium salts, POE-alkylamines, alkylamine salts, polyamine fatty acid derivatives, amyl alcohol fatty acid derivatives, benzalkonium chloride, and benzethonium chloride. Examples of quaternary ammonium salt type cationic surfactants include stearyltrimethylammonium chloride, cetyltrimethylammonium chloride, behenyltrimethylammonium chloride, stearyltrimethylammonium bromide, distearyldimethylammonium chloride, and laurylbenzyldimethylammonium chloride. Can be mentioned.

  Examples of amphoteric surfactants include imidazoline-based amphoteric surfactants such as 2-undecyl-N, N, N- (hydroxyethylcarboxymethyl) -2-imidazoline sodium, 2-heptadecyl-N-carboxymethyl-N- Examples thereof include betaine surfactants such as hydroxyethyl imidazolinium betaine, lauryldimethylaminoacetic acid betaine, alkyl betaine, amide betaine, and sulfobetaine.

  Examples of the lipophilic nonionic surfactant include sorbitan monooleate, sorbitan monoisostearate, sorbitan monolaurate, sorbitan monopalmitate, sorbitan fatty acid esters such as sorbitan monostearate, glyceryl monoerucate, sesquiolein Examples include glycerin fatty acids such as acid glycerin and glyceryl monostearate, propylene glycol fatty acid esters such as propylene glycol monostearate, hydrogenated castor oil derivatives, and glycerin alkyl ether.

  Examples of the hydrophilic nonionic surfactant include POE sorbitans such as POE sorbitan monooleate, POE sorbitan monostearate, POE sorbitan fatty acid esters, POE sorbit monolaurate, POE sorbit monooleate, and the like. Fatty acid esters, POE-glycerin monostearate, POE-glycerin monoisostearate, POE-glycerin fatty acid esters such as POE-glycerin triisostearate, POE-monooleate, POE-distearate, POE- such as POE-monodiolate Fatty acid esters, POE-lauryl ether, POE-oleyl ether, POE-stearyl ether, POE-alkyl ethers such as POE-behenyl ether, POE-octyl fe POE alkylphenyl ethers such as nyl ether, POE-nonylphenyl ether, POE-dinonylphenyl ether, pluronic types such as brulon, POE / POP cetyl ether, POE / POP-2-decyltetradecyl ether, POE / POP- POE / POP-alkyl ethers such as monobutyl ether, POE / POP-hydrogenated lanolin, tetra-POE / tetra-POP-ethylenediamine condensates such as Tetronic, POE-castor oil, POE-hardened castor oil, POE-hardened castor POE-castor oil hardened castor oil derivatives such as oil monoisostearate, POE-beeswax lanolin derivatives such as POE-sorbit beeswax, coconut oil fatty acid diethanolamide, lauric acid monoethanolamide, fatty acid isopate Examples include alkanolamides such as ropanolamide, POE-propylene glycol fatty acid ester, POE-alkylamine, POE-fatty acid amide, sucrose fatty acid ester, POE-nonylphenylformaldehyde condensate, alkylethoxydimethylamine oxide, and the like.

  Examples of the greasing agent include fats and oils, waxes, hydrocarbons, higher fatty acids, higher alcohols, and synthetic ester oils.

  As fats and oils, avocado oil, camellia oil, almond oil, macadamia nut oil, corn oil, grape seed oil, medfoam oil, olive oil, rapeseed oil, egg yolk oil, sesame oil, wheat germ oil, sasanqua oil, castor oil, safflower Oil, cottonseed oil, soybean oil, peanut oil, tea seed oil, kaya oil, rice bran oil, jojoba oil, germ oil, cocoa butter, palm oil, horse fat, hydrogenated palm oil, palm oil, beef tallow, sheep fat, hardened beef tallow, Examples include palm kernel oil, lard, tallow kernel oil, hydrogenated castor oil, and the like.

  The waxes include beeswax, candelilla wax, cotton wax, carnauba wax, moleberry, bayberry wax, ibota wax, whale wax, montan wax, nuka wax, lanolin, kapok wax, lanolin acetate, liquid lanolin, sugarcane wax, reduced lanolin, jojoballow, hard lanolin, shellac wax And POE lanolin alcohol ether.

  Examples of the hydrocarbon include liquid paraffin, ozokerite, squalene, paraffin, ceresin, petrolatum, and microcrystalline wax.

  Examples of the higher fatty acid include lauric acid, myristic acid, palmitic acid, stearic acid, behenic acid, oleic acid, 12-hydroxystearic acid, undecylenic acid, tolic acid, isostearic acid, linoleic acid, linolenic acid, ethyl alcohol Examples include icosapentaenoic acid (EPA) and docosahexaenoic acid (DHA).

  Examples of higher alcohols include linear alcohols such as lauryl alcohol, cetyl alcohol, stearyl alcohol, behenyl alcohol, myristyl alcohol, oleyl alcohol, cetostearyl alcohol, monostearyl glycerol ether (batyl alcohol), 2-decyltetradecinol, and lanolin. Examples thereof include branched chain alcohols such as alcohol, cholesterol, phytosterol, hexyldodecanol, isostearyl alcohol, and octyldodecanol.

Synthetic ester oils include isopropyl myristate, cetyl octanoate, octyldodecyl myristate, isopropyl palmitate, butyl stearate, hexyl laurate, myristyl myristate, decyl oleate, hexyl decyl dimethyloctanoate, cetyl lactate, myristyl lactate Lanolin acetate, isocetyl stearate, isocetyl isostearate, ethylene glycol di-2-ethylhexylate, dipentaerythritol fatty acid ester, N-alkyl glycol monoisostearate, neopentyl glycol dicaprate, diisostearyl malate, di-2 -Glyceryl heptyl undecanoate, trimethylolpropane tri-2-ethylhexylate, trimethylolpropane triisostearate, tetra-2 Pentaneerythritol ethylhexylate, glycerin tri-2-ethylhexylate, trimethylolpropane triisostearate, cetyl 2-ethylhexanoate, 2-ethylhexyl palmitate, glyceryl trimyristate, glyceride tri-2-heptylundecanoate, castor oil Fatty acid methyl ester, oleic oil, cetostearyl alcohol, acetoglyceride, 2-heptylundecyl palmitate, diisobutyl adipate, N-lauroyl-L-glutamic acid-2-octyldodecyl ester, di-2-heptylundecyl adipate , Ethyl laurate, di-2-ethylhexyl sebacate, 2-hexyldecyl myristate, 2-hexyldecyl palmitate, 2-hexyldecyl adipate, seba Phosphate diisopropyl, 2-ethylhexyl succinate, trioctanoate glycerin triisopalmitate glycerin, lanolin fatty acid isopropyl, hexyl laurate.

  Examples of hair protecting agents include chain polysiloxanes such as dimethylpolysiloxane, methylphenylpolysiloxane, and methylhydrogenpolysiloxane, and cyclic polysiloxanes such as decamethylpolysiloxane, dodecamethylpolysiloxane, and tetramethyltetrahydrogenpolysiloxane. Examples thereof include siloxane and silicone resin.

  As the humectant, for example, polyethylene glycol, propylene glycol, glycerin, 1,3-butylene glycol, sorbitol, maltitol, maltotriose, mannitol, sucrose, erythritol, glucose, fructose, amylolytic sugar, maltose, xylitol, Sugar alcohols such as amylolytic sugar-reduced alcohol, amino acids, chondroitin sulfate, hyaluronic acid, mucoitin sulfate, collagen derivatives, cholesteryl-12-hydroxystearate, sodium lactate, bile salts, seawater (including dried solids), ocean Examples include deep water (including dried solids), chitosan derivatives, sodium pyrrolidonecarboxylate, diglycerin / ethylene oxide / propylene oxide adducts, and the like.

  Examples of the polymers include natural water-soluble polymers, semi-synthetic water-soluble polymers, synthetic water-soluble polymers, and inorganic water-based polymers.

  Examples of natural water-soluble polymers include arabia gum, tragacanth gum, galactan, guar gum, carob gum, caraya gum, carrageenan, pectin, agar, quince seed (malmello), alge colloid (gypsum extract), starch (rice, corn, potato, wheat) ), Etc., microbial polymers such as dextran, succinoglucan and pullulan, and animal polymers such as casein, albumin and gelatin.

  Examples of semi-synthetic water-soluble polymers include starch polymers such as carboxymethyl starch and methylhydroxypropyl starch, methylcellulose, ethylcellulose, methylhydroxypropylcellulose, hydroxyethylcellulose, sodium cellulose sulfate, hydroxypropylcellulose, and carboxymethylcellulose sodium. (CMC), cellulose-based polymers such as crystalline cellulose and cellulose powder, and alginic acid-based polymers such as sodium alginate and propylene glycol alginate.

  Examples of the synthetic water-soluble polymer include vinyl polymers such as polyvinyl alcohol, polyvinyl methyl ether, polyvinyl pyrrolidone, and carboxyvinyl polymer, and polyoxyethylene polymers such as polyethylene glycol 20,000, 40,000, and 60,000. Examples thereof include polymers, copolymer polymers such as polyoxyethylene polyoxypropylene copolymer, acrylic polymers such as sodium polyacrylate, polyethyl acrylate, and polyacrylamide, polyethyleneimine, and cationized polymers.

  Examples of the inorganic water-based polymer include bentonite, magnesium aluminum silicate (beegum), laponite, hectorite, and anhydrous silicic acid.

  Examples of the ultraviolet absorber include paraaminobenzoic acid, ethyl paraaminobenzoate, glyceryl paraaminobenzoate, amyl paradimethylaminobenzoate, octyl paradimethylaminobenzoate, 4- [N, N-di (2-hydroxypropyl) Amino] benzoic acid UV absorbers such as ethyl benzoate, anthranilic acid UV absorbers such as homomenthyl-N-acetylanthranylate, ethylene glycol salicylate, phenyl salicylate, octyl salicylate, benzyl salicylate, p-tert-butyl salicylate Salicylic acid UV absorbers such as phenyl and homomenthyl salicylate, benzyl cinnamate, 2-ethoxyethyl paramethoxycinnamate, octyl paramethoxycinnamate, glyceryl mono-2-ethylhexanoate diparamethoxycinnamate Cinnamic acid UV absorbers such as isopropyl paramethoxycinnamate and diisopropyl cinnamate ester, urocanic acid UV absorbers such as urocanic acid and ethyl urocanate, hydroxymethoxybenzophenone, hydroxymethoxybenzophenonesulfonic acid, sodium hydroxymethoxybenzophenonesulfonate Benzophenone ultraviolet absorbers such as dihydroxydimethoxybenzophenone, sodium dihydroxydimethoxybenzophenone disulfonate, dihydroxybenzophenone, tetrahydroxybenzophenone, 4-tert-butyl-4′-methoxy-dibenzoylmethane, 2,4,6-trianilino-p -(Carbo-2'-ethylhexyl-1'-oxy) -1,3,5-triazine, 2- (2-hydroxy-5- Butylphenyl) benzotriazole.

  Examples of the metal sequestering agent include alanine, ethylenediamine hydroxyethyl triacetate, disodium edetate, trisodium edetate, tetrasodium edetate, sodium citrate, sodium polyphosphate, sodium metaphosphate, gluconic acid, tartaric acid, Examples include succinic acid, edetic acid, phytic acid and the like.

  Examples of the solvent include lower alcohols such as methanol, propanol, isopropanol, isobutyl alcohol, and t-butyl alcohol, ethylene glycol, propylene glycol, trimethylene glycol, 1,2-butylene glycol, 1,3-butylene glycol, Divalent alcohol such as glycerin, trimethylolpropane, trivalent alcohol such as 1,2,6-hexanetriol, tetravalent alcohol such as pentaerythritol, pentavalent alcohol such as xylitol, hexavalent such as sorbitol, mannitol, etc. Alcohol, diethylene glycol, dipropylene glycol, triethylene glycol, polypropylene glycol, tetraethylene glycol, diglycerin, polyethylene glycol, triglycerin, tetraglyceride Polyhydric alcohol polymers such as polyglycerin, dihydric alcohol alkyl ethers such as ethylene glycol monomethyl ether, dihydric alcohol alkyl ethers such as diethylene glycol monomethyl ether and diethylene glycol monoethyl ether, ethylene glycol monomethyl ether acetate, etc. Examples thereof include glycerin monoalkyl ethers such as dihydric alcohol ether esters, xyl alcohol, ceralkyl alcohol, and batyl alcohol.

  Examples of the pH adjuster include citric acid, lactic acid, acetic acid, hydrochloric acid, potassium hydroxide, sodium hydroxide, sodium lactate, sodium citrate, sodium lactate and the like. These can be used alone or in combination, and can be used not only for adjusting the pH value but also for the purpose of buffering the adjusted pH value.

  Examples of vitamins include vitamins A, B1, B2, B6, E and derivatives thereof, pantothenic acid and derivatives thereof, and the like.

  Examples of the antioxidant include tocopherols, dibutylhydroxytoluene, butylhydroxyanisole, gallic acid esters and the like.

  Examples of the preservative include organic acids such as benzoic acid, sodium benzoate, undecylenic acid, salicylic acid, sorbic acid, paraoxybenzoate, and derivatives thereof, phenols such as isopropylmethylphenol, phenoxyethanol, 1,2-hexanediol. 1,2-pentanediol and the like.

  Examples of the refreshing agent include l-menthol, menthyl lactate, 3- (menthyloxy) propane-1,2-diol, and the like.

  The form of the hair growth composition of the present invention is not particularly limited as long as it is a form used as a hair growth composition, for example, not only a liquid dosage form such as an aqueous solution (water type), lotion, cream, It may be in the form of a gel, paste, solid stick, powder, granule or the like.

  Moreover, the composition for hair growth of this invention can be used by making it contact with hair or a scalp. The method for contacting hair is not particularly limited, and examples thereof include a method of applying to hair and a method of spraying on hair or scalp.

  EXAMPLES Hereinafter, although an Example is given and this invention is demonstrated further in detail, this invention is not limited to the following example.

Production Example: Preparation of Hair Growth Composition A hair growth composition was prepared by mixing the components in the amounts shown in Examples 1 to 6 and Comparative Examples 1 to 5 in Table 1 below.

Test Example: Examination of Transparency The hair growth compositions of Examples 1 to 6 and Comparative Examples 1 to 5 prepared in the above production examples were allowed to stand for 2 months at −5 ° C., 25 ° C., and 40 ° C., respectively. The appearance of each hair growth composition after standing for 2 months was visually confirmed, and the transparency was evaluated according to the following criteria. The results are shown in the “Table 2 months after standing” column in Table 1 below.

○: Turbidity was not confirmed.
Δ: Some turbidity was confirmed.
X: Cloudiness was confirmed.

  Moreover, the photograph of the hair restoring composition of Examples 1-6 and Comparative Examples 1-5 after leaving for 2 months is shown in FIG. In addition, in FIG. 1, it respond | corresponds to Examples 1-6 and Comparative Examples 1-5 in an order from the left.

  Next, after being left for another month under the same conditions as described above, transmittance (unit:%, optical path length: 1 cm, temperature 25) at a wavelength of 500 nm using an ultraviolet-visible spectrophotometer (UV-2600, manufactured by Shimadzu Corporation). ° C). The results are shown in the column of “Transmittance after standing for 3 months (%)” in Table 1.

  In the hair growth composition (Comparative Examples 4 and 5) containing ougon extract and zinc gluconate, remarkable white turbidity was confirmed, whereas in addition to ougon extract and zinc gluconate, bisethoxydiglycol cyclohexanedicarboxylate was added. In the composition for hair restoration (Examples 1-5) to be included, cloudiness was not confirmed. Moreover, white turbidity was not confirmed by the hair growth composition (Comparative Examples 1-3) containing an orgone extract and cyclohexanedicarboxylic acid bisethoxydiglycol. From the above results, it was found that white turbidity was generated by combining ougon extract and zinc gluconate, and no white turbidity was generated by using bisethoxydiglycol cyclohexanedicarboxylate.

  Further, among Examples 1 to 5, in Examples 3, 5 and 6, slight turbidity was confirmed when left at 40 ° C., whereas in Examples 1, 2 and 4, it was left at 40 ° C. No cloudiness was observed even in the case of the test. From the above results, it is understood that the turbidity of the composition can be further suppressed by setting the ratio of bisethoxydiglycol cyclohexanedicarboxylate to zinc gluconate within a specific range (specifically, a value greater than 3). It was.

Claims (7)

(A): Ougon extract,
(B): a zinc compound, and (C): cyclohexanedicarboxylic acid,
General formula (1):
R— (OCH ₂ CH ₂ ) _n —OH (1)
[In general formula (1), R shows a C1-C12 alkyl group, n shows the integer of 2-11. ]
The composition for hair growth containing the diester with the polyoxyethylene monoalkyl ether represented by these. The hair growth composition according to claim 1, wherein a mass ratio of the C component to the B component (C component / B component) is greater than 3. The zinc compound is zinc gluconate, zinc chloride, zinc undecylenate, zinc stearate, zinc paraphenol sulfonate, zinc palmitate, zinc myristate, zinc laurate, basic zinc carbonate, zinc sulfate, zinc oxide, and The hair restoring composition according to claim 1 or 2, which is at least one selected from the group consisting of low-temperature fired zinc oxide. The hair restoring composition according to any one of claims 1 to 3, wherein the cyclohexanedicarboxylic acid is 1,4-cyclohexanedicarboxylic acid. The hair growth composition according to any one of claims 1 to 4, wherein the polyoxyethylene monoalkyl ether is diethylene glycol monoethyl ether. The hair growth composition according to any one of claims 1 to 5, comprising 0.1 to 10% by mass of the B component and 0.1 to 10% by mass of the C component. The composition for hair growth in any one of Claims 1-6 containing 0.1-10 mass% of said A components.