JP2018002304A - Package - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide a package at an inexpensive price, having a function which can prevent an infant and an older person to mistakenly drink a package including a content as it is, and damage a canal wall and the like, and allows an older person and a patient handicapped with fingers to easily open.SOLUTION: A package is obtained by welding a film or a sheet in which a recess (pocket) is molded in part with a lid material. Furthermore, the safe package which does not give damage to a canal wall in mistakenly drinking is obtained by making a cut body piece by cutting so as to be at least one pocket in a state that the lid material is welded with the film or sheet, and making a package which does not pierce into an aluminum foil when executing a piercing testing A, and does not cause damage or break in a testing plate when executing a piercing testing B or C.SELECTED DRAWING: Figure 1

Description

The present invention relates to a package that contains pharmaceuticals, cosmetics, and the like as contents, and more specifically, a package that can prevent a child or an elderly person from accidentally swallowing the package and damaging the digestive tract wall or the like. Provided at a low cost is a package body that has a function that can be opened easily even by an elderly person or a handicapped patient.

Conventionally, a package (hereinafter referred to as PTP) using a press-through package or a blister package has been widely used for packaging for storing solid substances such as tablets and capsules.

PTP encloses a film or sheet-like single layer or multilayer laminate in which recesses (pockets) for storing solids such as tablets and capsules are formed by heat, pressure, etc., and solids contained in the pockets. It is the packaging form which consists of a cover material for.

PTP is made into PTP in which the preparation is accommodated by thermally welding a lid material to the peripheral portion in a state where a solid preparation such as a tablet or a capsule is accommodated inside the pocket portion. The stored preparation can be taken out by pushing the pocket portion and tearing the lid part with the contained preparation itself, or by tearing the lid part with a finger.

  Further, the PTP is usually formed with a plurality of storage portions and perforations or slits for cutting the PTP for each predetermined number of storage portions.

  In such a PTP, when a perforation or a slit is formed, the section of the PTP cut body cut at the perforation or the slit is small and becomes a size that can enter the mouth as it is. There is a risk of being swallowed as it is by infants, children and the elderly. When PTP is accidentally swallowed in this way, there is a risk of damage to the digestive tract wall such as the esophagus and the gastrointestinal tract and the airway wall due to the peripheral portion of the accidentally swallowed PTP, which is sometimes broken through. (Perforated) is extremely dangerous because it causes a large amount of bleeding. In addition, for example, when the intestinal mucosa is perforated, peritonitis is caused, and particularly when the large intestine is perforated, fecal juice flows into the abdominal cavity and causes complications such as sepsis.

  Therefore, in order to prevent accidental ingestion of PTP, PTP in which the perforations or slits are formed only in one direction of the sheet has been proposed so that the plurality of storage portions are not separated one by one (Non-Patent Document). 1).

  However, even in such a case, since it easily enters the mouth, damage occurs at the peripheral edge of the PTP cut body. Even in the case of such a PTP in which such perforations or slits are formed in only one direction, perforations or slits are formed in medical sites and homes for reasons such as administration of administration and portability. If the sheet is further cut in a region that is not, the sheet may be cut so as to have one pocket. In this case, there is a possibility that the above-described accidental ingestion may occur. Thus, it is hard to say that the countermeasures against accidental ingestion of PTP are still sufficiently taken. On the other hand, elderly people and the like are weak in fingers, so that it is difficult to take out the contained objects when it is difficult to open the PTP package, and as a result, the medication may not be observed.

Patent Documents 1 and 2 propose a combination package of a paper package and PTP as a packaging form that is difficult for children to swallow. However, such a packaging form is effective in reducing the risk of accidental ingestion, but it can be separated or separated into a small packaging form. This is not preferable because it causes damage to the packaging material, resulting in a high cost of the packaging material and a decrease in productivity.

Patent Document 3 proposes a PTP that can prevent perforation of the digestive tract wall or the like by accidental ingestion. The sheet further includes a plurality of protrusions that reinforce the sheet formed so as to protrude in the same direction as the storage part, and the plurality of protrusions are arranged so as to surround the storage part. A plurality of recesses in between are arranged so as to form a pair on both sides with the accommodating portion interposed therebetween, and project when a cut body of a PTP package body is formed that is cut at the seal portion and has one accommodating portion. The part protrudes at the peripheral edge of the cut body, and the plurality of pairs of recesses constitutes the bent support shaft of the seal part, thereby providing a PTP package that does not perforate, as shown in FIGS. As shown in FIG. 6, it is clear that the cut body has a sharp corner and damages the digestive tract wall. Even if the cut body stops without being perforated, the damaged digestive tract wall Damaged by subsequent digestive tract activity It is considered that wounds of the gastrointestinal tract is widened, it goes without saying Such packaging is inadequate as a drinking measures erroneously aims not to damage the gastrointestinal tract. Even if the sheet has a flexural modulus of 5,000 kgf / cm ² or less, the digestive tract wall cannot be damaged.

  Patent Document 4 discloses a flexible plastic in which a softening agent is blended with a thermoplastic resin that is a base resin of a sheet, and the softening agent is an ester plasticizer, an elastomer, and a thermoplastic resin softer than the base resin. A sheet selected from the group consisting of a base resin made of polyvinyl chloride and polyolefin has been proposed. The tensile modulus of the base resin of the sheet is preferably 100 MPa or more and 1100 MPa or less from the viewpoint of shape retention and flexibility of the sheet. Is not appropriate and is not preferable as an index for aiming at an effect on gastrointestinal damage at the time of accidental ingestion. The packaging form at the time of accidental drinking of PTP is a state in which a blister sheet formed of a sheet and a metal foil such as an aluminum foil as a lid material are welded. In this document, a 300 μm thick sheet and a 20 μm aluminum foil are welded. It is PTP, and the corner of the cut body obtained by cutting the PTP is sufficiently sharp even if the sheet is flexible, and has not yet completely solved the problem as a countermeasure against accidental ingestion to prevent gastrointestinal damage. .

JP 2002-337938 A JP 2004-299724 A JP 2012-246033 A JP 2015-199503 A

“Caution! Accidental accident ingestion of medicine packaging sheets conspicuous to the elderly-swallowed PTP packaging may hurt the throat and esophagus, etc.” [online], published on September 15, 2010, National Life Center [Search on March 1, 2016] Internet <URL: http://www.kokusen.go.jp/news/data/n-20100915_1.html>

In view of the above problems, the present invention can prevent a child or elderly person from accidentally swallowing a PTP package and damaging the digestive tract wall, etc., and even an elderly person or a handicapped patient. The object is to provide a package having a function that can be easily opened at low cost.

In order to achieve the above-mentioned object, the present inventors have conducted intensive studies, and as a result, a film or sheet in which a recess (pocket) is partially molded and a cover material are welded to each other, When the cover material is welded to the film or sheet and cut into at least one pocket, a cut body is created, and when the piercing test A is performed, a package body that does not penetrate a certain standard aluminum foil is obtained. Or, when the piercing test B or C is performed, a safe package that does not damage the digestive tract even when accidentally swallowed is obtained by making the package that does not cause scratches or tears on the test plate of a certain standard. It was possible to solve the above-mentioned problems, and the present invention was made.

That is, the present invention provides the following package. The present invention has the following configuration.
Claim 1:
A package in which a film or sheet in which a recess (pocket) is partially formed and a lid material are welded, and the thickness of the film or sheet and the thickness of the lid material combined is 250 μm or less, A package body in which the total thickness of the film or sheet and the metal foil contained in the lid material is 35 μm or less or no metal foil is used, and the lid material is welded to the film or sheet of the package body Is cut at right angles to form a cut body, and when the following piercing test A is carried out, the package does not penetrate an aluminum foil having a thickness of 25 μm.
<Puncture test A>
The right-angled top of the cut piece cut at right angles is translated at a speed of 30 mm / min in a state where it is pressed against an aluminum foil stretched without wrinkles or slack with a load of 100 g.
Claim 2:
A package in which a film or sheet in which a recess (pocket) is partially formed and a lid material are welded, and the thickness of the film or sheet and the thickness of the lid material combined is 250 μm or less, A package body in which the total thickness of the film or sheet and the metal foil contained in the lid material is 35 μm or less or no metal foil is used, and the lid material is welded to the film or sheet of the package body A package characterized in that when the cut body is cut at right angles to make a cut body and the following piercing test B or C is carried out, the test plate is not damaged or torn.
<Puncture test B>
JIS K5600-5-4 scratch hardness (pencil method) is applied mutatis mutandis to the cut piece cut at a right angle, and fixed to a pencil hardness tester so that the right-angle top of the cut piece is in contact with the test plate instead of the pencil, A biosheet is used as the test plate, a load of 750 g is applied, and the test plate is translated in a horizontal state at a test speed of 1 mm / sec.
<Puncture test C>
JIS K5600-5-4 scratch hardness (pencil method) is applied to the cut piece cut at right angles, and fixed to a pencil hardness tester so that the right-angled top of the cut piece touches the test plate instead of the pencil, A polyethylene terephthalate film is used as the test plate, a load of 750 g is applied, and the test plate is moved in a horizontal state at a test speed of 1 mm / sec.
Claim 3:
In the film or sheet, the layer constituting the outermost layer contains at least one of cellophane, polyester resin, polyamide resin, polyethylene resin, polypropylene resin, and polyvinyl chloride resin as a main component, and the innermost layer The package according to claim 1 or 2, wherein the package is a laminate of at least two layers containing at least one of polyethylene resin, polypropylene resin and polyvinyl chloride resin as a main component. .
Claim 4:
In the cover material, the outermost layer contains at least one of cellophane, polyester resin, and polyamide resin as a main component, and the innermost layer is at least one of polyethylene resin, polypropylene resin, and polyvinyl chloride resin. It is comprised by the laminated body of the at least 2 layer or more comprised by the resin layer which contains one as a main component, or the raw material which expresses an easy peel, Any one of Claim 1 to 3 characterized by the above-mentioned Package according to crab.
Claim 5:
The package according to any one of claims 1 to 3, wherein the lid member is a metal foil coated with a sealing agent having a sealing property.
Claim 6:
The package according to any one of claims 1 to 5, wherein the film or sheet has a softening temperature of an outermost layer lower than a softening temperature of an innermost layer.
Claim 7:
The package according to any one of claims 1 to 6, wherein an opening inducing portion by a blade or a laser is provided on one or both of the film or sheet and the lid.
Claim 8:
8. The laser marking ink is printed between the layers on at least one of a film or sheet laminated in multiple layers or a cover laminated in multiple layers on the package. The package in any one of.
Claim 9:
The package is characterized in that an unwelded portion in which a film or sheet and a lid member are not welded is provided on at least two opposite sides of a cut body obtained by separating and cutting the contents individually. The package in any one of 8-8.
Claim 10:
9. The package according to claim 1, wherein an unwelded portion in which the film or sheet and the lid member are not welded is provided on the entire periphery of the cut body obtained by individually separating and cutting the contents. The package in any one.

The package of the present invention can prevent children and the elderly from accidentally ingesting the PTP package and damaging the digestive tract wall, etc., and can be easily opened even by the elderly or a handicapped patient. For the purpose of providing inexpensively a package having a function that can be performed, a film or sheet in which a recess (pocket) is partially molded and a package formed by welding a lid material, the film or Cut the section where the lid material was welded to the sheet at right angles to make a cut body, and when the piercing test A was carried out, do not penetrate the 25 μm thick aluminum foil, or pierce test B or C As a package characterized in that scratches and tears do not occur on the test plate, it is inexpensive and excellent in practicality.
Details are as follows.
According to the invention of claim 1, in the PTP in which the sheet or film in which the pocket is molded and the lid material are welded, in the medical field or at home, the pocket unit is used for convenience such as administration of administration and portability. In the case where the cut body becomes a size that easily enters the mouth and accidentally swallows, the combined thickness of the film or sheet and the lid material is 250 μm or less. In addition, when the total thickness of the metal foil contained in the film or sheet and the lid member is 35 μm or less or the package does not use the metal foil, the piercing test A does not penetrate the aluminum foil. Since it is so soft, it is possible to obtain a safe package that does not damage the digestive tract at the sharp corners of the cut body.
According to the invention of claim 2, in the PTP in which the sheet or film in which the pocket is formed and the lid material are welded, in the medical field or at home, the pocket unit is used for convenience such as administration and portability. In the case where the cut body becomes a size that easily enters the mouth and accidentally swallows, the combined thickness of the film or sheet and the lid material is 250 μm or less. By making the packaging body in which the total thickness of the metal foil contained in the film or sheet and the cover material is 35 μm or less or not using the metal foil, the test plate is scratched or torn by the piercing test B or C Therefore, it is possible to obtain a safe package that does not damage the digestive tract at the sharp corners of the cut body.
According to invention of Claim 3, the layer which comprises the outermost layer of the film or sheet | seat in which the recessed part (pocket) was shape | molded in part is made of cellophane, polyester resin, polyamide resin, polyethylene resin, polypropylene resin, poly A laminate of at least two or more layers including at least one of polyvinyl chloride resins as a main component, and the innermost layer including at least one of polyethylene resins, polypropylene resins, and polyvinyl chloride resins as a main component. By setting it as a body, it can be set as the sheet | seat or film which has the moldability of a pocket, intensity | strength, and a softness | flexibility.
According to the invention of claim 4, it is possible to have sufficient strength for storing and distributing the contents even when the lid is made thin, and it is easy to impart barrier properties such as water vapor and oxygen. It becomes. When the film or sheet and the lid are welded, the package can be made flexible. Moreover, it becomes easy to give easy peel property, and it can further help to increase the effect of preventing accidental ingestion in children.
According to the invention of claim 5, even when a metal foil such as an aluminum foil is used for the cover material in order to improve the take-out property, the total thickness of the film or sheet and the metal foil contained in the cover material is 35 μm. If it is below, damage to the digestive tract and the like during accidental ingestion can be prevented.
According to invention of Claim 6, since the softening temperature of an outermost layer is lower than the softening temperature of an innermost layer, the moldability at the time of shape | molding a pocket by thermoforming improves, and a molding speed is increased. It becomes possible to manufacture an inexpensive packaging body by improving productivity.
According to the invention of claim 7, conventionally, the contents are taken out by pushing a pocket to break a metal foil such as aluminum or directly breaking a metal foil such as aluminum by hand. Alternatively, by taking out the opening / opening guiding portion by means of a blade or a laser on both sides, it becomes possible to tear the packaging body by hand and take out the contents. Such an opening method is particularly effective for preventing accidental ingestion in children.
According to the invention of claim 8, in the medical field or at home, even if the sheet is cut so as to have one pocket for reasons such as administration of administration and portability, it will be Whether it is a drug product, and the expiration date and expiration date are clear, and it can be helpful for the remaining medicine to be discarded. In addition, since the laser marking ink is applied between the layers of the laminate, it cannot be counterfeited or tampered with, and the safety can be improved at any time.
According to the ninth aspect of the invention, when cut into at least one pocket, an unwelded portion where the film or sheet and the lid member are not welded is exposed at the corner of the cut body, and therefore there is a risk of damaging the digestive tract. It can be further lowered.
According to the invention of claim 10, since the unwelded portion where the film or sheet and the lid material are not welded is exposed on the entire circumference of the cut body when cut into one pocket, the risk of damaging the digestive tract is further increased. It can be lowered.

It is a schematic diagram which illustrates the shape of the package which concerns on embodiment of this invention. It is a side view of the schematic diagram of FIG. It is a schematic diagram which illustrates the shape of the package when the easy opening of this invention is given. (A) is a schematic diagram illustrating the shape of the package when the unwelded portion of the present invention is applied, and (b) and (c) are schematic diagrams illustrating the shape of the package separated into two pockets or one pocket. FIG. It is a schematic diagram of the piercing test A. (A) (d) is a schematic diagram illustrating the shape of a package when an unwelded portion is applied to the entire circumference of the present invention, and (b), (c), (e), and (f) are two packages. It is a schematic diagram which illustrates the shape cut | disconnected in the pocket or 1 pocket. It is a schematic diagram of the piercing tests B and C.

Hereinafter, preferred embodiments of the package according to the present invention will be described. The technical scope of the present invention is not limited only to the following description and drawings.

  In the package of the present invention, the innermost layer refers to a layer that is on the inner surface side of the package of the present invention and is in direct contact with the contents contained in the package.

  In the package of the present invention, the outermost layer is the outer surface side of the package of the present invention, and refers to a layer that becomes the outermost layer of the package and contacts the outside of the package.

The packaging body 1 of the present invention is a packaging body 1 in which a film or sheet 2 in which a recess (pocket 4) is formed in part and a lid material 3 are welded. Such as pharmaceuticals, quasi-drugs, functional foods, health foods, etc. Such a package 1 is often provided with a perforation or slit 5 for separation into one pocket or two pockets for carrying or taking, and the form separated by the perforation or slit 5. As a result, children and elderly people accidentally swallow the entire package, which may damage the digestive tract, which is a social problem. As a countermeasure, a package with enhanced flexibility of the sheet itself has been proposed for a long time, but the package is not a sheet alone, but a lid material is welded. It cannot prevent the digestive tract from being damaged. According to the present invention, when the thickness of the film or sheet 2 and the lid material 3 is 250 μm or less, preferably 220 μm or less, more preferably 170 μm or less, the penetration test A penetrates the aluminum foil 9. The test plate 10 is not scratched or torn by the piercing test B or C. If it exceeds 250 μm, even if a flexible material is used for the package 1, the piercing test A penetrates the aluminum foil 9, and the piercing test B or C causes scratches and tears on the test plate 10. Therefore, the possibility of damaging the digestive tract due to the corners of the cut PTP is undesirable. Further, if the total thickness of the metal foil contained in the film or sheet 2 and the lid 3 is 35 μm or less, preferably 30 μm or less, it cannot penetrate the aluminum foil 9 by the piercing test A. The test B or C is preferable because the test plate 10 is not damaged or torn, and the risk of damaging the digestive tract by the corners of the PTP cut body 8 is reduced. Further, when no metal foil is used, the PTP cut body 8 becomes more flexible and more preferable.
The thickness of the film or sheet 2 alone is preferably 50 μm or more, and if it is less than 50 μm, the moisture resistance and the moldability of the pocket are deteriorated.

In the present invention, the film or sheet 2 in which the recess (pocket 4) is partially formed is composed of cellophane, polyester-based resin, polyamide-based resin, polyethylene-based resin, polypropylene-based resin, and polychlorinated resin. A laminate of at least two or more layers including at least one of vinyl resins as a main component and an innermost layer including at least one of polyethylene resin, polypropylene resin, and polyvinyl chloride resin as a main component. There is no particular limitation other than that, and a laminate of three or more layers may be used. The layers other than the outermost layer and the innermost layer include a layer for imparting flexibility, an adhesive resin layer with each layer, oxygen, Generally used materials such as a barrier layer against moisture can be widely used. In addition, a coating layer for imparting moisture resistance such as a PVDC coating agent to the resin layer constituting the innermost layer is brought into direct contact with the contents so as to be in a coating amount range of 1 to 30 g / m ² or less. May be provided. If it exceeds 30 g / m ² , the film or sheet becomes hard, and it is not preferable, and if it is less than 1 g / m ^2, it is not preferable from the viewpoint of imparting moisture resistance. Although the layer constituting the outermost layer may be unstretched or stretched, if it is composed of a stretched film, the thickness of the film or sheet 2 may be reduced in order to reduce the thickness of the entire package as much as possible. The strength can be maintained, which is preferable. Further, printing can be performed between layers, which is preferable from the viewpoint of the effect of preventing falsification of printing.

As a method for producing the film or sheet 2, a conventionally known method can be used and there is no particular limitation. Multi-layer coextrusion method, extrusion lamination method, coextrusion inflation method such as coextrusion inflation method and coextrusion T-die method, dry lamination method, coextrusion water cooling inflation, heat lamination, etc., conventionally known methods alone or in combination Layers can be configured. As a method for adhering the layers, an adhesive resin (including simply an adhesive resin) may be used, or an anchor agent or an adhesive may be used. Moreover, there is no restriction | limiting in particular in the manufacturing method, and the conventionally well-known method can be used for the resin and film of each layer which comprise.
As the adhesive, organic adhesives such as two-component curable polyester urethane adhesives, polyether urethane adhesives, and epoxy adhesives can be appropriately selected.
As the anchor agent, generally used anchor agents such as polyurethane, polyether, alkyl titanate (organotitanium compound), etc. can be used and can be appropriately selected.

As the layer for imparting flexibility, a conventionally known resin or film for imparting flexibility such as polyethylene resin, polypropylene resin, ethylene elastomer, propylene elastomer, and styrene elastomer can be used. There may be a single layer, a single resin or a blend of a plurality of types with other resins to form a layer, or two or more layers.

As the adhesive resin, a conventionally known resin can be used as long as it has excellent adhesion to different materials, and a single resin or a plurality of resins can be used. Examples thereof include low density polyethylene, linear low density polyethylene, and acid-modified polyolefin resin. The linear low density polyethylene is more preferably a linear low density polyethylene (LLDPE) polymerized using a metallocene catalyst. Specific examples of resins suitable as the acid-modified polyolefin resin include metal-crosslinked polyethylene (ionomer), ethylene-acrylic acid copolymer (EAA), ethylene-methacrylic acid copolymer (EMAA), and ethylene-ethyl acrylate copolymer. Examples include coalesced (EEA), maleic anhydride-modified polyethylene, and maleic anhydride-modified polypropylene. Examples of the unsaturated carboxylic acid graft-polymerized to the raw material of the acid-modified polyolefin resin include acrylic acid, methacrylic acid, maleic acid, fumaric acid, itaconic acid, citraconic acid, or acid anhydrides, esters, amides, imides thereof. And derivatives such as metal salts. In addition, a resin in which epoxidized polybutadiene is blended with low density polyethylene, linear low density polyethylene, polypropyne, or the like may be used.

As the barrier layer, a metal foil layer made of aluminum foil or alloy foil, a PVDC resin or film, a film coated with PVDC, a cyclic olefin resin, EVOH, PVA resin or a coating thereof, MXD nylon, fluorine resin, or the like is used. can do. These films and resins may be used alone or in combination.

Examples of the fluororesin include polytetrafluoroethylene (abbreviation: PTFE), polychlorotrifluoride ethylene (polychlorotrifluoroethylene abbreviation: PCTFE, CTFE), polyvinylidene fluoride (abbreviation: PVDF), and polyvinyl fluoride (abbreviation: PVF), perfluoroalkoxy fluororesin (abbreviation: PFA), tetrafluoroethylene / hexafluoropropylene copolymer (abbreviation: FEP), ethylene and -tetrafluoroethylene copolymer (abbreviation: ETFE), ethylene / chloro Trifluoroethylene copolymer (abbreviation: ECTFE), tetrafluoroethylene / perfluoroalkyl vinyl ether copolymer resin, perfluoroethylene-propene copolymer (FEP), polyvinylidene fluoride (PVdF), perfluoroethylene-pro Rene copolymer, perfluoroethylene propene copolymer, polyvinylidene fluoride, polychlorotrifluoroethine, tetrafluoroethylene-perfluorodioxole copolymer, polyvinyl fluoride, EFEP with improved adhesion, tetra And fluoroethylene / perfluoro (alkyl vinyl ether) / chlorotrifluoroethylene copolymer (CPT). Of these, polychloroethylene trifluoride (PCTFE) is more preferable because it can reduce the thickness for providing a moisture blocking effect.

  The structure of the lid 3 of the present invention is such that the outermost layer contains at least one of cellophane, polyester resin, and polyamide resin as a main component, and the innermost layer includes polyethylene resin, polypropylene resin, and polyvinyl chloride resin. Except that it is composed of a resin layer containing at least one of the above as a main component, or the innermost layer is composed of a material that expresses an easy peel, and is composed of a laminate of at least two layers. There is no restriction | limiting in particular, A laminated body of three or more layers may be sufficient, and generally used materials can be widely used for the layers other than the outermost layer and the innermost layer. The layer constituting the outermost layer may be unstretched or stretched. However, when it is composed of a stretched film, the strength of the cover is reduced even if the thickness of the lid is reduced in order to make the entire package as thin as possible. It is possible to keep and is preferable. Further, printing can be performed between layers, which is preferable from the viewpoint of the effect of preventing falsification of printing.

As a manufacturing method of the said cover material 3, a conventionally well-known method can be used and there is no restriction | limiting in particular. Multi-layer coextrusion method, extrusion laminating method, coextrusion laminating method such as coextrusion inflation method and coextrusion T-die method, dry laminating method, coextrusion water cooling inflation, heat lamination, gravure coating, die coating, Mayer bar coating, comma reverse coating In addition, a layer can be formed by using a known method such as a coating method such as comma direct coating, air knife coating, kiss coating, hot melt coating or the like alone or in combination. As a method of bonding the layers, an adhesive resin may be used, or an anchor agent or an adhesive may be used. Moreover, there is no restriction | limiting in particular in the manufacturing method, and the conventionally well-known method can be used for the resin and film of each layer which comprise.
As the adhesive, organic adhesives such as two-component curable polyester urethane adhesives, polyether urethane adhesives, and epoxy adhesives can be appropriately selected.
As the anchor agent, generally used anchor agents such as polyurethane, polyether, alkyl titanate (organotitanium compound), etc. can be used and can be appropriately selected.

As the layer for imparting flexibility, a conventionally known resin or film for imparting flexibility such as polyethylene resin, polypropylene resin, ethylene elastomer, propylene elastomer, and styrene elastomer can be used. There may be a single layer, a single resin or a blend of a plurality of types with other resins to form a layer, or two or more layers.

As the adhesive resin, a conventionally known resin can be used as long as it has excellent adhesion to different materials, and a single resin or a plurality of resins can be used. Examples thereof include low density polyethylene, linear low density polyethylene, and acid-modified polyolefin resin. The linear low density polyethylene is more preferably a linear low density polyethylene (LLDPE) polymerized using a metallocene catalyst. Specific examples of resins suitable as the acid-modified polyolefin resin include metal-crosslinked polyethylene (ionomer), ethylene-acrylic acid copolymer (EAA), ethylene-methacrylic acid copolymer (EMAA), and ethylene-ethyl acrylate copolymer. Examples include coalesced (EEA), maleic anhydride-modified polyethylene, and maleic anhydride-modified polypropylene. Examples of the unsaturated carboxylic acid graft-polymerized to the raw material of the acid-modified polyolefin resin include acrylic acid, methacrylic acid, maleic acid, fumaric acid, itaconic acid, citraconic acid, or acid anhydrides, esters, amides, imides thereof. And derivatives such as metal salts. In addition, a resin in which epoxidized polybutadiene is blended with low density polyethylene, linear low density polyethylene, polypropyne, or the like may be used.

As the barrier layer, a metal foil layer made of aluminum foil or alloy foil, silica or alumina vapor-deposited PET film or vapor-deposited nylon film, aluminum vapor-deposited PET, aluminum vapor-deposited nylon, organic and / or inorganic nanocomposite resin or organic and / or Alternatively, an inorganic nanocomposite coat film, a film coated with PVDC or PVDC, a cyclic olefin resin, EVOH, PVA resin or a coat thereof, PVDC resin or a coat thereof, MXD nylon, or the like can be used. These films and resins may be used alone or in combination.

In the easy peel layer, the peel strength of the welded portion with a film or sheet in which a recess (pocket) is formed in part is 1 N / 15 mm or more and 15 N / 15 mm or less, preferably 2 N / 15 mm or more and 10 N / 15 mm or less. More preferably. If it is lower than 1 N / 15 mm, it is not preferable because there is a risk of opening in the distribution process, and if it exceeds 15 N / 15 mm, it is difficult to open easily, which is not preferable.

  As such an easy peel layer, a conventionally known film or resin can be used. Moreover, a coating, a hot melt agent, etc. can also be used. Since the thickness of the easy heel layer affects the price of the package, the thicker the package, the more expensive the package, which is not preferable, and it is more preferably 70 μm or less, more preferably 50 μm or less.

As another configuration of the lid member 3 of the present invention, a metal foil coated with a coating agent having a sealing property may be used. As for the thickness of the metal foil, the total thickness of the metal foil used for the film or sheet 2 and the lid 3 may be 35 μm or less, but if it is 20 μm or less, the flexibility of the package 1 will increase. Preferably, the contents can be easily taken out. Conventionally known coating agents can be widely used as the coating agent, and any material can be used as long as it can adhere well to the metal foil when thermally welded to the film or sheet 2. As the coating agent, it is preferable to use a coating agent mainly composed of the same resin as the film or sheet 2 or a mixture of specific resins. For example, when the innermost layer of the film or sheet 2 is composed of a layer containing a polypropylene resin as a main component, an adhesive coating agent for polypropylene is used and the layer is composed of a layer containing a polyethylene resin as a main component. Sometimes an adhesive coating agent for polyethylene is used, and when it is composed of a layer containing a polyvinyl chloride resin as a main component, an adhesive coating agent for polyvinyl chloride resin is used.

  The film or sheet 2 can increase the heating temperature from the outermost layer side even when the pocket 4 is formed at a higher speed than usual by making the softening temperature of the outermost layer lower than the softening temperature of the innermost layer. This makes it possible to improve the moldability when the pocket 4 is formed by thermoforming, to increase the forming speed, and it is possible to manufacture the inexpensive package 1 by improving the productivity. As an index of the softening temperature of the outermost layer and the innermost layer, it is most preferable to compare the melting points, and the melting point of the outermost layer is more preferably 10 ° C. or higher than the melting point of the innermost layer from the viewpoint of high-speed moldability. The next preferred index after the melting point is the softening temperature (JIS K6734). This is used as an index for amorphous materials such as cyclic olefins and polyvinyl chlorides that do not exhibit a melting point.For example, a material that exhibits a melting point is used for the outermost layer, and a material that does not exhibit a melting point is used for the innermost layer. In this case, the high-temperature formability of the pocket can be obtained by simply comparing the temperatures of the melting point and the softening temperature and increasing the outermost layer by 10 ° C. or more.

In order to take out the contents, it has been common in the past to take out the contents by pushing the pocket 4 of the package 1 to break the metal foil such as aluminum or directly breaking the metal foil such as aluminum by hand. However, in the present invention, one or both of the film or sheet 2 and the lid member 3 are provided with the opening guide 6 by a blade or a laser, so that the package itself can be torn by hand to easily take out the contents. Things will be possible. Such an opening method is particularly effective for preventing accidental ingestion in children. As a method for applying the opening guide 6, for example, by a method using a metal blade such as a die cut or a Thomson blade, the outermost layer or an inner layer other than the innermost layer is punched, or the base material layer is irradiated by carbon dioxide laser irradiation. The opening guide 6 can be formed by ablation or the like. The shape of the opening guide portion 6 is not particularly limited, but the cut portion may be provided continuously, but the cut portion (cutting portion) and the non-cut portion (non-cut portion) in a broken line shape. It is more preferable that the cutting portions are alternately and continuously provided, because the effects of both the provision of unsealability and the risk of being unsuccessfully unsealed during distribution before unsealment are most easily exhibited. When cut portions and non-cut portions are alternately and continuously provided, the length is preferably in the range of 0.05 mm or more and 1.5 mm or less, and is preferably 0.1 mm or more and 1.0 mm or less. When it exists, it is more preferable from a viewpoint of linear cut property. The lengths of the cut part and the non-cut part may be different from each other within this range.
The easy-opening guide section 6 may be disposed anywhere in the package as long as it can be opened and the contents can be taken out, preferably in parallel to the long side of the package. More preferably, they are arranged.

Laser marking ink is printed on at least one of the multilayered film or sheet 2 or the multilayered lid material 3, more preferably on the lid material 3 side. Preferably, one laser marking ink is printed on all pockets, so that there is one pocket 4 in the medical field or home for reasons such as administration and portability. In such cases, the expiration date, expiry date, serial number, two-dimensional barcode, etc. are clearly identified. It is easy, and the remaining medicine is not discarded, which can help reduce medical costs. Since the laser king ink is printed between the layers, the laser king ink is not directly exposed to the outside and cannot be tampered with later. There are no particular restrictions on the composition and materials of such laser marking inks, as long as the ink layer applied between the layers can be colored for the first time by irradiating a laser from the outside to identify characters, etc. Conventionally known inks can be used. Further, by printing ink between layers, it is possible not only to prevent tampering but also to prevent the gas generated by laser irradiation from scattering to the outside.

  Since the corners of the cut body 8 become sharp when cut into at least one pocket, in the present invention, the film or sheet 2 and the lid 3 are welded, not the flexibility of the film or sheet 2 having the pocket 4. Even if the cut body 8 is accidentally swallowed, the digestive tract is damaged by focusing on the package 1 itself and defining the total thickness of the package 1 and the thickness of the metal foil used in the packaging bag. A package without a sheet is proposed, but more preferably, when cut into at least one pocket, the film or sheet 2 and the lid are formed on at least two opposite sides of the cut body 8, more preferably on the entire circumference of the cut body. By forming the welded portion so that there is an unwelded portion 7 that is not welded to the material 3, the unwelded portion is always exposed at the corner of the cut body 8. To do It is possible.

  The dimensions of the pocket 4 of the package 1 are as follows: length +2.0 to +20.0 mm, width +2.0 to 20.0 mm, height +0.1 to +3.0 mm with respect to the size of the contents (formulation). It is more preferable to prevent accidental ingestion.

  In the present invention, the main component refers to the case where the content of the component is 50% by weight or more.

  Next, the present invention will be described in more detail with reference to Examples, Comparative Examples, and Test Examples, but the present invention is not limited to these.

[Examples and Comparative Examples]
The detailed configuration of the film and sheet 2 and the lid 3 is specifically shown in Table 1.

In addition, as a material constituting the package, the outermost layer is a to e below, the innermost layer is I to V below, the barrier layer is A to C below, and the layers i to v are used to give adhesiveness and flexibility. did.
a: Biaxially stretched nylon film (Unitika emblem)
b: Biaxially stretched polyester film (Toyobo Ester)
c: Polypropylene (MFR1.6 Mitsubishi Chemical Zelas)
d: Silica vapor-deposited nylon film (Mitsubishi Resin Tech Barrier)
e: Alumina-deposited polyester film (GL film manufactured by Toppan Printing)

I: LLDPE linear low density polyethylene (MFR8 made by Nippon Polyethylene Harmolex)
II: Polypropylene (MFR3.0 Mitsubishi Chemical Zelas)
III: Polyvinyl chloride film (Mitsubishi resin vinyl foil)
IV: Easy peel film (Toray film processable CF film)
V: Easy peel film (CMPS manufactured by Mitsui Chemicals Tosero)

A: Aluminum foil (1N30 made of UACJ foil)
B: PVDC (Asahi Kasei Saran-UB)
C: PCTFE (PCTFE manufactured by Honeywell)

i: Two-component curable polyester urethane adhesive (Takelac / Takenate manufactured by Mitsui Chemicals, Inc.)
ii: Anchor agent two-component solvent type polyurethane (Nippon Soda Chitabond)
iii: LLDPE linear low density polyethylene (MFR8 made by Nippon Polyethylene Harmolex)
iv: 50% by weight of MFR8 polyethylene (Sumitomo Chemical LDPE), 50% by weight of MFR10 styrene elastomer (SEBS KRATON manufactured by Kraton Polymer)
v: MFR20 polypropylene elastomer (Mitsubishi Chemical Zelas) 50% by weight, MFR7 polypropylene (Nippon Polypro Wintech) 30% by weight, MFR8 polyethylene (Nippon Polyethylene Harmolex) 10% by weight, MFR10 styrene elastomer (SEBS KRATON manufactured by Kraton Polymer Co.) 10 wt% blend.

LI: Laser marking ink (Ebima, Toyo Ink)

[Production Method 1]
The films or sheets of Examples 1, 2, 4, 11, and 12 were produced by the extrusion laminating method as the configuration shown in Table 1.
The films or sheets of Examples 3, 5, 7, and 10 and Comparative Example 2 and the lid materials of Examples 1 to 7 and 10 were produced by the dry laminating method as shown in Table 1.
The films or sheets of Examples 6, 8, and 9 and Comparative Example 1 were produced by the multilayer coextrusion method as shown in Table 1.
The lid materials of Examples 8, 9, 11, and 12 and Comparative Examples 1 and 2 were prepared by the gravure coating method as the configuration shown in Table 1.
Then, the film or sheet and the innermost layer side of the cover material are opposed to each other, and a pocket is produced by a molding machine manufactured by CKD Co., Ltd. so as to be inside the pocket, and the cover material is thermally welded and sealed. A package was produced.
[Perforation]
For the films or sheets of Examples 1, 4, and 10, easy opening using a film in which perforations in which a cut portion and a non-cut portion are continuously connected to a biaxially stretched nylon film at intervals of 0.8 mm is put with a die roll. A guide wire was inserted to improve the opening.
In Example 2, the film or sheet is a biaxially stretched polyester film, and the lid is a biaxially stretched nylon film. Using the film put in, an easy-open guide wire was inserted to improve the openability.
[Unwelded part]
In Examples 10, 11, and 12, when the film or sheet and the lid material are welded and sealed, even if the pocket is cut into at least one, the welding is performed so that an unwelded portion appears at all corners. Yes.

[Evaluation method]
The following evaluation was performed about the package of this invention.

<Puncture test A>
The package in a state where the cover material is welded to the film or sheet is cut with a cutter so as to form one pocket, and a cut piece with a corner of the cut piece being 90 degrees is created. This cut piece is set on a Clemens type scratch hardness tester (manufactured by Tester Sangyo) using a special mounting part for gripping the test piece instead of a needle. At this time, the cut piece is set so that the sharp corner is positioned downward so as to hold the position 5 mm from the apex of the corner and to make the angle 45 degrees. On the other hand, a 25 μm aluminum foil (1N30 H18 as defined in JIS H 4160) is set in a hardness tester in a stretched state without wrinkles or slack. It is confirmed that when the test piece is slid at a speed of 30 mm / min with a load of 100 g applied to the aluminum foil, the cut aluminum piece does not penetrate.

<Puncture test B>
The package in a state where the cover material is welded to the film or sheet is cut with a cutter so as to form one pocket, and a cut piece with a corner of the cut piece being 90 degrees is created. The above cut piece is set in a pencil hardness tester (manufactured by Tester Sangyo) instead of the pencil. At this time, the sharp angle is set downward so that the angle is 45 degrees. As a test plate, a bio sheet medium type (HXBNXTB858510MX manufactured by Wetrab) is used, the load is set to 750 g according to JIS K5600-5-4 scratch hardness (pencil method), and the test is performed at a speed of 1 mm / sec in a horizontal state. Do. After the test, visually check the test plate to make sure that there are no scratches or tears.

<Puncture test C>
The test is performed in the same manner as the puncture test B except that a polyethylene terephthalate (PET) film (thickness 20 μm) is used instead of the biosheet as a test plate for the puncture test B. After the test, visually check the test plate to make sure there are no scratches, tears, rub marks, or tears.

DESCRIPTION OF SYMBOLS 1 Package 2 Film or sheet 3 Lid 4 Pocket 5 Perforation or slit 6 Opening guide part 7 Unwelded part 8 Cut body 9 Aluminum foil 10 Test plate

Claims (10)

A package in which a film or sheet in which a recess (pocket) is partially formed and a lid material are welded, and the thickness of the film or sheet and the thickness of the lid material combined is 250 μm or less, A package body in which the total thickness of the film or sheet and the metal foil contained in the lid material is 35 μm or less or no metal foil is used, and the lid material is welded to the film or sheet of the package body Is cut at right angles to form a cut body, and when the following piercing test A is carried out, the package does not penetrate an aluminum foil having a thickness of 25 μm.
<Puncture test A>
The right-angled top of the cut piece cut at right angles is translated at a speed of 30 mm / min in a state where it is pressed against an aluminum foil stretched without wrinkles or slack with a load of 100 g. A package in which a film or sheet in which a recess (pocket) is partially formed and a lid material are welded, and the thickness of the film or sheet and the thickness of the lid material combined is 250 μm or less, A package body in which the total thickness of the film or sheet and the metal foil contained in the lid material is 35 μm or less or no metal foil is used, and the lid material is welded to the film or sheet of the package body A package characterized in that when the cut body is cut at right angles to make a cut body and the following piercing test B or C is carried out, the test plate is not damaged or torn.
<Puncture test B>
JIS K5600-5-4 scratch hardness (pencil method) is applied mutatis mutandis to the cut piece cut at a right angle, and fixed to a pencil hardness tester so that the right-angle top of the cut piece is in contact with the test plate instead of the pencil, A biosheet is used as the test plate, a load of 750 g is applied, and the plate is translated in a horizontal state at a speed of 1 mm / sec.
<Puncture test C>
JIS K5600-5-4 scratch hardness (pencil method) is applied to the cut piece cut at right angles, and fixed to a pencil hardness tester so that the right-angled top of the cut piece touches the test plate instead of the pencil, A polyethylene terephthalate film is used as the test plate, a load of 750 g is applied, and the test plate is translated in a horizontal state at a speed of 1 mm / sec.   In the film or sheet, the layer constituting the outermost layer contains at least one of cellophane, polyester resin, polyamide resin, polyethylene resin, polypropylene resin, and polyvinyl chloride resin as a main component, and the innermost layer The package according to claim 1 or 2, wherein the package is a laminate of at least two layers containing at least one of polyethylene resin, polypropylene resin and polyvinyl chloride resin as a main component. .   In the cover material, the outermost layer contains at least one of cellophane, polyester resin, and polyamide resin as a main component, and the innermost layer is at least one of polyethylene resin, polypropylene resin, and polyvinyl chloride resin. It is comprised by the laminated body of the at least 2 layer or more comprised by the resin layer which contains one as a main component, or the raw material which expresses an easy peel, Any one of Claim 1 to 3 characterized by the above-mentioned Package according to crab. The package according to any one of claims 1 to 3, wherein the lid member is a metal foil coated with a sealing agent having a sealing property. The package according to any one of claims 1 to 5, wherein the film or sheet has a softening temperature of an outermost layer lower than a softening temperature of an innermost layer. The package according to any one of claims 1 to 6, wherein an opening inducing portion by a blade or a laser is provided on one or both of the film or sheet and the lid.   8. The laser marking ink is printed between the layers on at least one of a film or sheet laminated in multiple layers or a cover laminated in multiple layers on the package. The package in any one of.   The package is characterized in that an unwelded portion in which a film or sheet and a lid member are not welded is provided on at least two opposite sides of a cut body obtained by separating and cutting the contents individually. The package in any one of 8-8. 9. The package according to claim 1, wherein an unwelded portion in which the film or sheet and the lid member are not welded is provided on the entire periphery of the cut body obtained by individually separating and cutting the contents. The package in any one.

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