JP2017537973A5 - - Google Patents

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Publication number
JP2017537973A5
JP2017537973A5 JP2017540317A JP2017540317A JP2017537973A5 JP 2017537973 A5 JP2017537973 A5 JP 2017537973A5 JP 2017540317 A JP2017540317 A JP 2017540317A JP 2017540317 A JP2017540317 A JP 2017540317A JP 2017537973 A5 JP2017537973 A5 JP 2017537973A5
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JP
Japan
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patient
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composition
item
day
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JP2017540317A
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English (en)
Japanese (ja)
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JP2017537973A (ja
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Priority claimed from PCT/EP2015/074070 external-priority patent/WO2016059243A2/en
Publication of JP2017537973A publication Critical patent/JP2017537973A/ja
Publication of JP2017537973A5 publication Critical patent/JP2017537973A5/ja
Pending legal-status Critical Current

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JP2017540317A 2014-10-17 2015-10-16 バイオマーカーレベルを使用してsmad7アンチセンスオリゴヌクレオチドを投与するおよびモニタリングするための方法 Pending JP2017537973A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201462065586P 2014-10-17 2014-10-17
US201462065596P 2014-10-17 2014-10-17
US62/065,596 2014-10-17
US62/065,586 2014-10-17
US201462085949P 2014-12-01 2014-12-01
US62/085,949 2014-12-01
PCT/EP2015/074070 WO2016059243A2 (en) 2014-10-17 2015-10-16 Methods for dosing and monitoring smad7 antisense oligonucleotide treatment using biomarker levels

Publications (2)

Publication Number Publication Date
JP2017537973A JP2017537973A (ja) 2017-12-21
JP2017537973A5 true JP2017537973A5 (https=) 2018-11-29

Family

ID=54356321

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2017540317A Pending JP2017537973A (ja) 2014-10-17 2015-10-16 バイオマーカーレベルを使用してsmad7アンチセンスオリゴヌクレオチドを投与するおよびモニタリングするための方法

Country Status (5)

Country Link
US (2) US20170233736A1 (https=)
EP (2) EP3693736A3 (https=)
JP (1) JP2017537973A (https=)
CA (1) CA2964673A1 (https=)
WO (1) WO2016059243A2 (https=)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITRM20030149A1 (it) 2003-04-02 2004-10-03 Giuliani Spa Oligonucleotidi (odn) antisenso per smad7 e loro usi in campo medico
ES2627745T3 (es) 2008-11-13 2017-07-31 Nogra Pharma Limited Composiciones antisentido, y procedimientos de fabricación y uso de las mismas
ES2617200T3 (es) 2011-09-15 2017-06-15 Nogra Pharma Limited Procedimientos para supervisar la capacidad de respuesta al tratamiento anti-SMAD7
US10081809B2 (en) 2012-04-18 2018-09-25 University Of Miami Methods of treating diabetes and/or promoting survival of pancreatic islets after transplantation
US10006029B2 (en) 2013-03-15 2018-06-26 Nogra Pharma Limited Methods of treating colorectal cancer
AU2015257589A1 (en) 2014-05-09 2016-11-24 Nogra Pharma Limited Methods for treating inflammatory bowel disease
WO2016059239A1 (en) 2014-10-17 2016-04-21 Nogra Pharma Limited Methods and compositions for treating a subject with a smad7 antisense oligonucleotide
MA41271A (fr) * 2014-12-26 2017-10-31 Celgene Alpine Invest Company Ii Llc Méthodes d'utilisation d'oligonucléotides antisens ciblant smad7
JP2019505598A (ja) 2016-02-23 2019-02-28 セルジーン アルパイン インベストメント カンパニー Ii, エルエルシー Smad7の阻害を用いて、腸線維症を治療する方法
MX2019001249A (es) 2016-08-15 2019-04-25 Intercontinental Great Brands Llc Pelicula de capas multiples y empaque de pelicula que puede volver a cerrarse.
WO2018035044A1 (en) 2016-08-15 2018-02-22 Intercontinental Great Brands Llc Multi-layer film and reclosable film package

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6159697A (en) 2000-01-19 2000-12-12 Isis Pharmaceuticals, Inc. Antisense modulation of Smad7 expression
ITRM20030149A1 (it) * 2003-04-02 2004-10-03 Giuliani Spa Oligonucleotidi (odn) antisenso per smad7 e loro usi in campo medico
US20110212104A1 (en) * 2008-11-03 2011-09-01 Schering Corporation Inflammatory bowel disease biomarkers and related methods of treatment
ES2627745T3 (es) 2008-11-13 2017-07-31 Nogra Pharma Limited Composiciones antisentido, y procedimientos de fabricación y uso de las mismas
ES2617200T3 (es) * 2011-09-15 2017-06-15 Nogra Pharma Limited Procedimientos para supervisar la capacidad de respuesta al tratamiento anti-SMAD7
US20150125398A1 (en) * 2012-05-11 2015-05-07 University Of Iowa Research Foundation Multimodal imaging methods using mesoporous silica nanoparticles
WO2016059239A1 (en) * 2014-10-17 2016-04-21 Nogra Pharma Limited Methods and compositions for treating a subject with a smad7 antisense oligonucleotide

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